JP6064186B2 - Tomm34ペプチドおよびそれを含むワクチン - Google Patents

Tomm34ペプチドおよびそれを含むワクチン Download PDF

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JP6064186B2
JP6064186B2 JP2013525055A JP2013525055A JP6064186B2 JP 6064186 B2 JP6064186 B2 JP 6064186B2 JP 2013525055 A JP2013525055 A JP 2013525055A JP 2013525055 A JP2013525055 A JP 2013525055A JP 6064186 B2 JP6064186 B2 JP 6064186B2
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peptide
present
cancer
peptides
tomm34
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JP2014506114A (ja
JP2014506114A5 (OSRAM
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中村 祐輔
祐輔 中村
卓也 角田
卓也 角田
龍司 大沢
龍司 大沢
祥子 吉村
祥子 吉村
朝久 渡辺
朝久 渡辺
岳 中山
岳 中山
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Oncotherapy Science Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0634Cells from the blood or the immune system
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • C12N5/0638Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
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    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
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    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5158Antigen-pulsed cells, e.g. T-cells
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    • A61K2039/53DNA (RNA) vaccination
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
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  • Epidemiology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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JP2013525055A 2010-12-02 2011-11-25 Tomm34ペプチドおよびそれを含むワクチン Active JP6064186B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41918110P 2010-12-02 2010-12-02
US61/419,181 2010-12-02
PCT/JP2011/006551 WO2012073459A1 (en) 2010-12-02 2011-11-25 Tomm34 peptides and vaccines including the same

Related Child Applications (1)

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JP2016121469A Division JP2016222676A (ja) 2010-12-02 2016-06-20 Tomm34ペプチドおよびそれを含むワクチン

Publications (3)

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JP2014506114A JP2014506114A (ja) 2014-03-13
JP2014506114A5 JP2014506114A5 (OSRAM) 2015-01-15
JP6064186B2 true JP6064186B2 (ja) 2017-01-25

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JP2013525055A Active JP6064186B2 (ja) 2010-12-02 2011-11-25 Tomm34ペプチドおよびそれを含むワクチン
JP2016121469A Withdrawn JP2016222676A (ja) 2010-12-02 2016-06-20 Tomm34ペプチドおよびそれを含むワクチン

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US (3) US9125849B2 (OSRAM)
EP (1) EP2646546B1 (OSRAM)
JP (2) JP6064186B2 (OSRAM)
KR (1) KR102004900B1 (OSRAM)
CN (2) CN103339253B (OSRAM)
AR (1) AR084095A1 (OSRAM)
AU (1) AU2011336019B2 (OSRAM)
BR (1) BR112013013158B1 (OSRAM)
CA (1) CA2819463C (OSRAM)
CO (1) CO6862100A2 (OSRAM)
DK (1) DK2646546T3 (OSRAM)
EA (1) EA028216B1 (OSRAM)
ES (1) ES2677118T3 (OSRAM)
IL (1) IL226068B (OSRAM)
MX (1) MX344586B (OSRAM)
MY (1) MY166516A (OSRAM)
NZ (1) NZ611361A (OSRAM)
PH (1) PH12013501105A1 (OSRAM)
SG (2) SG10201509823WA (OSRAM)
TW (1) TWI618541B (OSRAM)
UA (1) UA110119C2 (OSRAM)
WO (1) WO2012073459A1 (OSRAM)
ZA (1) ZA201303886B (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013317194B2 (en) 2012-09-11 2018-07-12 Oncotherapy Science, Inc. UBE2T peptides and vaccines containing the same
JP2015228191A (ja) * 2014-06-03 2015-12-17 カシオ計算機株式会社 コンテンツ出力システム、コンテンツ出力方法、コンテンツ出力プログラム、および通信端末
WO2017150084A1 (ja) * 2016-02-29 2017-09-08 京セラドキュメントソリューションズ株式会社 電子機器およびマーカー処理方法
MX2019008878A (es) 2017-01-25 2020-02-13 Ose Immunotherapeutics Metodo para fabricar una emulsion estable para suministro de peptidos.

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5785973A (en) 1988-02-01 1998-07-28 Praxis Biologics, Inc. Synthetic peptides representing a T-cell epitope as a carrier molecule for conjugate vaccines
US5539084A (en) 1989-02-17 1996-07-23 Coselco Mimotopes Pty. Ltd. Method for the use and synthesis of peptides
CA2158655A1 (en) * 1993-03-19 1994-09-29 Max L. Birnstiel Process for preparing cancer vaccines
US5840839A (en) 1996-02-09 1998-11-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein
AU2926601A (en) 2000-01-03 2001-07-16 Argonex Pharmaceuticals, Inc. C-ski oncogene-derived peptides for prevention, treatment, and diagnosis of cancer
US7700359B2 (en) 2000-06-02 2010-04-20 Novartis Vaccines And Diagnostics, Inc. Gene products differentially expressed in cancerous cells
US20040181344A1 (en) 2002-01-29 2004-09-16 Massachusetts Institute Of Technology Systems and methods for providing diagnostic services
JP4594085B2 (ja) * 2002-06-06 2010-12-08 オンコセラピー・サイエンス株式会社 ヒト結腸癌に関連する遺伝子およびポリペプチド
WO2004018667A1 (ja) 2002-08-26 2004-03-04 Kirin Beer Kabushiki Kaisha ペプチド及びこれを含む医薬
CN101139392B (zh) 2002-09-12 2012-12-26 肿瘤疗法科学股份有限公司 Kdr肽和包括该肽的疫苗
DE602004015064D1 (de) 2003-01-06 2008-08-28 Wyeth Corp Zusammensetzungen und verfahren zur diagnose und behandlung von kolonkrebs
PL1620456T3 (pl) * 2003-04-18 2014-06-30 Ose Pharma Int Sa Peptydy antygenu związanego z nowotworem HLA-A2 i kompozycje
AU2006273192B2 (en) * 2005-07-27 2011-09-01 Oncotherapy Science, Inc. Colon cancer related gene TOM34
SI1760089T1 (sl) * 2005-09-05 2009-12-31 Immatics Biotechnologies Gmbh S tumorjem povezani peptidi, ki se veĹľejo na molekule humanega levkocitnega antigena (HLA) razreda I ali II in ustrezno cepivo proti raku
TWI610939B (zh) * 2007-02-21 2018-01-11 腫瘤療法 科學股份有限公司 表現腫瘤相關抗原之癌症的胜肽疫苗
TW201425333A (zh) * 2007-04-11 2014-07-01 Oncotherapy Science Inc 腫瘤血管內皮標誌8胜肽及包含此胜肽之疫苗
MX2011007963A (es) * 2009-03-18 2011-08-17 Oncotherapy Science Inc Peptidos neil3 y vacunas que incluyen los mismos.

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CA2819463C (en) 2018-10-23
SG190407A1 (en) 2013-06-28
EP2646546A4 (en) 2015-12-23
US9585948B2 (en) 2017-03-07
US20150374810A1 (en) 2015-12-31
EP2646546B1 (en) 2018-05-16
IL226068A0 (en) 2013-06-27
CN103339253A (zh) 2013-10-02
IL226068B (en) 2019-01-31
KR20130121910A (ko) 2013-11-06
ES2677118T3 (es) 2018-07-30
NZ611361A (en) 2014-10-31
EA028216B1 (ru) 2017-10-31
UA110119C2 (xx) 2015-11-25
BR112013013158B1 (pt) 2020-04-28
CO6862100A2 (es) 2014-02-10
US20170198010A1 (en) 2017-07-13
EP2646546A1 (en) 2013-10-09
JP2016222676A (ja) 2016-12-28
PH12013501105A1 (en) 2013-08-05
AR084095A1 (es) 2013-04-17
US20140023671A1 (en) 2014-01-23
AU2011336019A1 (en) 2013-07-04
JP2014506114A (ja) 2014-03-13
MX344586B (es) 2016-12-20
MX2013006014A (es) 2013-07-29
CA2819463A1 (en) 2012-06-07
TWI618541B (zh) 2018-03-21
WO2012073459A1 (en) 2012-06-07
AU2011336019B2 (en) 2016-07-07
US9125849B2 (en) 2015-09-08
SG10201509823WA (en) 2015-12-30
KR102004900B1 (ko) 2019-07-29
CN103339253B (zh) 2015-09-09
BR112013013158A2 (pt) 2017-08-01
CN105111281A (zh) 2015-12-02
MY166516A (en) 2018-07-05
DK2646546T3 (en) 2018-08-06
TW201225973A (en) 2012-07-01
ZA201303886B (en) 2014-03-26
EA201390811A1 (ru) 2013-12-30

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