JP6059211B2 - サイトミックな血管健康プロファイリングのシステムおよび方法 - Google Patents

サイトミックな血管健康プロファイリングのシステムおよび方法 Download PDF

Info

Publication number
JP6059211B2
JP6059211B2 JP2014514915A JP2014514915A JP6059211B2 JP 6059211 B2 JP6059211 B2 JP 6059211B2 JP 2014514915 A JP2014514915 A JP 2014514915A JP 2014514915 A JP2014514915 A JP 2014514915A JP 6059211 B2 JP6059211 B2 JP 6059211B2
Authority
JP
Japan
Prior art keywords
subject
level
risk
progenitor cell
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2014514915A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014517313A5 (enExample
JP2014517313A (ja
Inventor
エミール アール． モーラ
エミール アール． モーラ
ジョニ エス． ムーア
ジョニ エス． ムーア
リフォン チャン
リフォン チャン
ウェイド ロジャース
ウェイド ロジャース
アンドリュー ディー． バントリー
アンドリュー ディー． バントリー
Original Assignee
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア, ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア filed Critical ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
Publication of JP2014517313A publication Critical patent/JP2014517313A/ja
Publication of JP2014517313A5 publication Critical patent/JP2014517313A5/ja
Application granted granted Critical
Publication of JP6059211B2 publication Critical patent/JP6059211B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2014514915A 2011-06-10 2012-06-10 サイトミックな血管健康プロファイリングのシステムおよび方法 Expired - Fee Related JP6059211B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161495955P 2011-06-10 2011-06-10
US61/495,955 2011-06-10
US201261650353P 2012-05-22 2012-05-22
US61/650,353 2012-05-22
PCT/US2012/041792 WO2012170974A1 (en) 2011-06-10 2012-06-10 System and method of cytomic vascular health profiling

Publications (3)

Publication Number Publication Date
JP2014517313A JP2014517313A (ja) 2014-07-17
JP2014517313A5 JP2014517313A5 (enExample) 2015-06-11
JP6059211B2 true JP6059211B2 (ja) 2017-01-11

Family

ID=47296510

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014514915A Expired - Fee Related JP6059211B2 (ja) 2011-06-10 2012-06-10 サイトミックな血管健康プロファイリングのシステムおよび方法

Country Status (7)

Country Link
US (1) US20140357505A1 (enExample)
EP (1) EP2717681A4 (enExample)
JP (1) JP6059211B2 (enExample)
CN (1) CN104039134A (enExample)
AU (1) AU2012267489B2 (enExample)
CA (1) CA2838436A1 (enExample)
WO (1) WO2012170974A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015134791A2 (en) * 2014-03-07 2015-09-11 University Of Washington - Center For Commercialization Non-invasive biomarker of antibody-mediated allograft rejection
JP2015123503A (ja) * 2014-08-21 2015-07-06 千住金属工業株式会社 真空はんだ処理装置及びその制御方法
JP2018505392A (ja) * 2014-12-10 2018-02-22 ネオゲノミクス ラボラトリーズ， インコーポレイテッド 自動化されたフローサイトメトリ分析方法及びシステム
FR3030039B1 (fr) * 2014-12-12 2018-03-16 Commissariat A L'energie Atomique Et Aux Energies Alternatives Caracterisation et reproduction d'un jugement d'expert pour une classification binaire
CA3012985A1 (en) 2015-01-27 2016-08-04 Kardiatonos, Inc. Biomarkers of vascular disease
ES2829235T3 (es) * 2015-05-07 2021-05-31 Oncoimmune Inc Uso de CD24 para disminuir los niveles de colesterol en lipoproteínas de baja densidad
WO2017162722A1 (en) * 2016-03-22 2017-09-28 INSERM (Institut National de la Santé et de la Recherche Médicale) Free functional annexin levels in plasma as a biomarker of cardiovascular risk
JPWO2020138351A1 (enExample) * 2018-12-28 2020-07-02
CN116359488A (zh) * 2021-12-27 2023-06-30 北京积水潭医院 检测血液样本中不同类型微颗粒含量的方法
CN114674729B (zh) * 2022-03-02 2023-11-21 迈克医疗电子有限公司 脉冲识别方法、装置、存储介质、设备及血液细胞分析仪
CN120778688A (zh) * 2025-07-09 2025-10-14 广州市微米生物科技有限公司 一种流式检测试剂在肿瘤疾病的出血风险等级分类产品中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090233999A1 (en) * 1999-09-06 2009-09-17 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
US7708977B2 (en) * 2002-11-15 2010-05-04 The United States Of America As Represented By The Department Of Health And Human Services Method for diagnosis and treatment of vascular disease
WO2005069003A1 (en) * 2003-06-27 2005-07-28 Oklahoma Medical Research Foundation Methods for predicting susceptibility to cardiovascular disease
US20050272098A1 (en) * 2004-04-23 2005-12-08 Tramontano Anthony F Quantitation of endothelial microparticles
US20060078553A1 (en) * 2004-10-07 2006-04-13 Paul Glidden Diverse multi-unit complexes including a tRNA synthetase fragment
US20100203058A1 (en) * 2009-02-11 2010-08-12 Indiana University Research And Technology Corporation Diagnostics and therapeutics based on circulating progenitor cells
WO2011000874A1 (en) * 2009-07-01 2011-01-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting cardiovascular mortality risk

Also Published As

Publication number Publication date
AU2012267489B2 (en) 2017-03-16
CA2838436A1 (en) 2012-12-13
WO2012170974A1 (en) 2012-12-13
JP2014517313A (ja) 2014-07-17
EP2717681A1 (en) 2014-04-16
US20140357505A1 (en) 2014-12-04
EP2717681A4 (en) 2015-01-07
AU2012267489A1 (en) 2014-01-09
CN104039134A (zh) 2014-09-10

Similar Documents

Publication Publication Date Title
JP6059211B2 (ja) サイトミックな血管健康プロファイリングのシステムおよび方法
Urrechaga et al. Role of leucocytes cell population data in the early detection of sepsis
Kim et al. Circulating levels of DNA-histone complex and dsDNA are independent prognostic factors of disseminated intravascular coagulation
Sen et al. Is a complete blood cell count useful in determining the prognosis of pulmonary embolism?
Wekesa et al. Predicting carotid artery disease and plaque instability from cell-derived microparticles
Berezin et al. Pattern of circulating microparticles in chronic heart failure patients with metabolic syndrome: Relevance to neurohumoral and inflammatory activation
Yifan et al. Development and validation of a random forest diagnostic model of acute myocardial infarction based on ferroptosis-related genes in circulating endothelial cells
Wang et al. Differences of inflammatory and non-inflammatory indicators in Coronavirus disease-19 (COVID-19) with different severity
Sciacchitano et al. Gene signature and immune cell profiling by high-dimensional, single-cell analysis in COVID-19 patients, presenting Low T3 syndrome and coexistent hematological malignancies
Forest et al. Circulating microparticles and procoagulant activity in elderly patients
KR102044940B1 (ko) 파종성 혈관 내 응고 증후군 또는 감염성 파종성 혈관 내 응고 증후군을 검출하는 방법
JP7605502B2 (ja) Ｄｍａｒｄに対する患者の応答を予測する方法
Rose et al. Flow cytometric quantification of peripheral blood cell β-adrenergic receptor density and urinary endothelial cell-derived microparticles in pulmonary arterial hypertension
Shteinshnaider et al. Prognostic significance of changes in red cell distribution width in an internal medicine ward
Turgut et al. Differences in platelet–leukocyte aggregates among subtypes of acute cerebral ischemia
Meggyes et al. Can there be calm during a cytokine storm? Immune checkpoint pathways affecting the severity of COVID-19 disease
US20120129708A1 (en) Compositions and methods for predicting cardiovascular events
EP2534491B1 (en) Compositons and methods for predicting cardiovascular events
US20200209242A1 (en) Cancer diagnosis using ki-67
US20200116736A1 (en) Methods for Diagnosing and Treating Subjects for Pulmonary Exacerbation
Chatterjee et al. Biomarkers of Infection and Inflammation
De Simone et al. Circulating endothelial cell levels in psoriatic patients and their modification after an anti‐TNF‐alpha (Etanercept) treatment
FI130377B (en) Procedure for determining whether a subject is at risk of developing an anxiety disorder
Maréchal et al. Neutrophil dynamics in acute coronary syndrome
Wang et al. Mucosal‐associated invariant T cells correlate with myocardial ischaemia and remodelling in coronary artery disease

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140609

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20140609

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150414

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20150414

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20150526

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20160113

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20160118

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20160415

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160526

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20161026

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20161124

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20161208

R150 Certificate of patent or registration of utility model

Ref document number: 6059211

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

LAPS Cancellation because of no payment of annual fees