JP6050805B2 - ステント - Google Patents
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- JP6050805B2 JP6050805B2 JP2014505724A JP2014505724A JP6050805B2 JP 6050805 B2 JP6050805 B2 JP 6050805B2 JP 2014505724 A JP2014505724 A JP 2014505724A JP 2014505724 A JP2014505724 A JP 2014505724A JP 6050805 B2 JP6050805 B2 JP 6050805B2
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- 239000013543 active substance Substances 0.000 claims description 3
- 210000004204 blood vessel Anatomy 0.000 description 24
- 230000003902 lesion Effects 0.000 description 20
- 238000000034 method Methods 0.000 description 13
- 238000002513 implantation Methods 0.000 description 11
- 230000002792 vascular Effects 0.000 description 10
- 210000001367 artery Anatomy 0.000 description 8
- 210000004351 coronary vessel Anatomy 0.000 description 7
- 238000002399 angioplasty Methods 0.000 description 5
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
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- 208000007536 Thrombosis Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001028 anti-proliverative effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127217 antithrombotic drug Drugs 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/91525—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
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- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
- A61F2002/91541—Adjacent bands are arranged out of phase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/9155—Adjacent bands being connected to each other
- A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/0054—V-shaped
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
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- F04C2270/04—Force
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Prostheses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Description
a)Tstrut−径方向のストラット厚さ(押出管の厚さ)
b)Wstrut−周方向のストラット幅
c)lc−第1の中央環6及び第2の中央環6’のそれぞれの山部7、7’間の中央リンク28の半分の長さ
d)llink−隣接し合う環のそれぞれの最大幅の山部と最大幅の谷部との間のリンク11、12、19、22の長さ
e)wlink−11、12、19、22の周方向幅(Wstrutと同様)
f)NoX−軸方向の(すなわち、長手方向軸4に対して平行な)セルの数
g)NoY−周方向のセルの数
h)Lstent−ステント1の総長
i)Rstent−ステント1の予め収縮した内径(押出管の内径)
j)darc−リンク位置における円弧/半円の直径
k)w−第1の中央環6の山部7と谷部8との間の、長手方向軸4に対して平行な距離
l)f−係数であって、この係数だけ、(第1の中央環6以外の)各環9、13、16、17の最小幅がそれらのそれぞれの最大幅よりも小さい、係数
m)rc−第1の中央環6及び第2の中央環6’によって画定されているセルの中央リンク28の円弧の半径。
a)dh−周方向の各セルの四分の一長
b)e−連続した環の長さ(すなわち、最大幅の山部から最大幅の谷部までの、長手方向軸に対して平行な方向の距離)間の比
c)
理論上、Wstrutの下限及び上限はそれぞれゼロ及びdhである。
Claims (14)
- 第1の端部及び第2の端部と、該第1の端部と該第2の端部との間に長手方向軸とを有する、管状ステントであって、該管状ステントは、前記長手方向軸の回りに円筒面を画定する、ストラットの網状構造から形成され、前記ストラットは、前記網状構造内に複数のセルの境界を定め、前記長手方向軸に対して平行なセル列があり、各列内の少なくとも1つのセルが節点セルであり、該少なくとも1つの節点セルから、前記列内の、該管状ステントの前記第1の端部又は前記第2の端部により近い第1の遠位セルにかけてのセルの、前記長手方向軸に対して平行な最大長さが増加しており、前記列内に、前記節点セル及び前記第1の遠位セルとは異なる、前記長手方向軸に対して平行な最大長さを有する第2の遠位セルがあり、ストラットの前記網状構造は、周方向の複数の環を含み、各環は、前記長手方向軸に対して垂直に延び、前記環は、前記円筒面を画定するように前記長手方向軸に対して平行に互いに隣接して位置付けられており、前記周方向の環は波形をなし、各周方向の環は、各波形が、該管状ステントの軸方向中心側に延びる複数の山部と、該管状ステントの前記軸方向中心に面しない側に延びる複数の谷部とを含むように、前記長手方向軸に対して平行な幅を有し、
前記周方向の環は、周方向の節点環と周方向の遠位環とを含み、前記周方向の節点環は、該管状ステントの前記少なくとも1つの節点セルを画定し、隣接し合う周方向の節点環は、該周方向の節点環のそれぞれの山部及び/又は谷部が互いと位置合わせされて互いに結合されるように位置合わせされており、したがって、前記周方向の節点環は各セル列の前記少なくとも1つの節点セルを画定しており、
前記周方向の節点環及び前記周方向の遠位環は、第1の周方向の遠位環が第2の周方向の遠位環又は周方向の節点環に隣接している場合、前記第1の周方向の遠位環の波形の山部の少なくとも幾つかが、前記第2の周方向の遠位環又は前記周方向の節点環の波形の谷部の少なくとも幾つかと位置合わせされるように位置合わせされており、また、隣接し合う周方向の環が前記網状構造内のセルを画定するように互いに結合されており、
各周方向の遠位環は、最大幅の山部及び谷部と最小幅の山部及び谷部とが交互になっている波形を有し、
前記周方向の遠位環の前記最大幅の山部及び谷部の頂点から頂点までの幅は、周方向の節点環に比較的より近い周方向の遠位環から、前記周方向の節点環から比較的より遠い周方向の遠位環にかけて段階的に増加しており、
前記最大幅の山部及び谷部の前記頂点から頂点までの幅は幾何学的に増加していることを特徴とする、管状ステント。 - 請求項1に記載の管状ステントであって、該ステントは収縮性である、請求項1に記載の管状ステント。
- 請求項1又は2に記載の管状ステントであって、該管状ステントの前記節点セルから前記第1の遠位セルにかけてのセルの、前記長手方向軸に対して平行な最大長さの前記増加は、幾何学的増加による成分を含む、請求項1又は2に記載の管状ステント。
- 隣接し合う周方向の遠位環は、前記最大幅の山部及び谷部によってのみ互いに結合される、請求項1〜3のいずれか1項に記載の管状ステント。
- 請求項1〜3のいずれか1項に記載の管状ステントであって、前記隣接し合う周方向の遠位環の少なくとも幾つかは、前記最大幅の山部及び谷部によって、また、前記最小幅の山部及び谷部によって互いに結合される、請求項1〜3のいずれか1項に記載の管状ステント。
- 周方向の節点環に比較的より近い周方向の遠位環から、周方向の節点環から比較的より遠い周方向の遠位環にかけて、前記周方向の遠位環の前記最小幅の山部及び谷部の頂点から頂点までの幅の増加がある、請求項1〜5に記載の管状ステント。
- 前記周方向の遠位環の前記最小幅の山部及び谷部の前記頂点から頂点までの幅は、周方向の節点環に比較的より近い周方向の遠位環から、前記周方向の節点環から比較的より遠い周方向の遠位環にかけて段階的に増加している、請求項6に記載の管状ステント。
- 前記最小幅の山部及び谷部の前記頂点から頂点までの幅は幾何学的に増加している、請求項6又は7に記載の管状ステント。
- 前記少なくとも1つの節点セルは閉じたセルである、請求項1〜8のいずれか1項に記載の管状ステント。
- 請求項1〜9のいずれか1項に記載の管状ステントであって、前記少なくとも1つの節点セルから、該管状ステントの前記第1の端部に比較的より近い遠位セルにかけてのセルの、前記長手方向軸に対して平行な前記最大長さは、前記少なくとも1つの節点セルから、該管状ステントの前記第2の端部に比較的より近い遠位セルにかけてのセルの、前記長手方向軸に対して平行な前記最大長さが増加している割合とは異なる割合で増加している、請求項1〜9のいずれか1項に記載の管状ステント。
- 請求項1〜10のいずれか1項に記載の管状ステントであって、前記第1の節点セルよりも、該管状ステントの前記端部のうちの一方に近い第2の節点セルがあり、前記第1の節点セルと前記第2の節点セルとの間に遠位セルがあり、各節点セルから該節点セル間の前記遠位セルにかけてのセルの、前記長手方向軸に対して平行な前記最大長さは、増加している、請求項1〜10のいずれか1項に記載の管状ステント。
- 前記第1の節点セルと前記第2の節点セルとの間に第3の節点セルがあり、前記第1の節点セルと前記第3の節点セルとの間に第1の中間の遠位セルと、前記第2の節点セルと前記第3の節点セルとの間に第2の中間の遠位セルとがあり、前記第1の節点セル及び前記第3の節点セルのそれぞれから前記第1の中間の遠位セルにかけての、また、前記第2の節点セル及び前記第3の節点セルのそれぞれから前記第2の中間の遠位セルにかけてのセルの、前記長手方向軸に対して平行な前記最大長さは、増加している、請求項1〜11のいずれか1項に記載の管状ステント。
- 請求項1〜12のいずれか1項に記載の管状ステントであって、前記少なくとも1つの節点セルは、該管状ステントの前記軸方向中心に最も近いセル(単数又は複数)である、請求項1〜12のいずれか1項に記載の管状ステント。
- 請求項1〜13のいずれか1項に記載の管状ステントであって、薬学的に活性な作用物質が該管状ステントに放出可能に付随している、請求項1〜13のいずれか1項に記載の管状ステント。
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PCT/GB2012/050882 WO2012143731A1 (en) | 2011-04-20 | 2012-04-20 | A stent |
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US10390977B2 (en) | 2011-06-03 | 2019-08-27 | Intact Vascular, Inc. | Endovascular implant |
WO2013112768A1 (en) | 2012-01-25 | 2013-08-01 | Intact Vascular, Inc. | Endoluminal device and method |
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US9180031B2 (en) | 2013-03-15 | 2015-11-10 | Covidien Lp | Stent with varying radius between struts |
US9433520B2 (en) | 2015-01-29 | 2016-09-06 | Intact Vascular, Inc. | Delivery device and method of delivery |
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US10993824B2 (en) | 2016-01-01 | 2021-05-04 | Intact Vascular, Inc. | Delivery device and method of delivery |
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ES2555478T3 (es) | 2016-01-04 |
WO2012143731A1 (en) | 2012-10-26 |
CA2833216C (en) | 2019-01-22 |
US20160120668A1 (en) | 2016-05-05 |
CN103596524B (zh) | 2016-04-20 |
JP2014514111A (ja) | 2014-06-19 |
EP2699207B1 (en) | 2015-10-07 |
MY168327A (en) | 2018-10-30 |
AU2012246086A1 (en) | 2013-04-18 |
CN103596524A (zh) | 2014-02-19 |
US20140107764A1 (en) | 2014-04-17 |
US9707109B2 (en) | 2017-07-18 |
CA2833216A1 (en) | 2012-10-26 |
GB201106757D0 (en) | 2011-06-01 |
SG194192A1 (en) | 2013-11-29 |
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