JP6049621B2 - 分析物の分離 - Google Patents

分析物の分離 Download PDF

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Publication number
JP6049621B2
JP6049621B2 JP2013530348A JP2013530348A JP6049621B2 JP 6049621 B2 JP6049621 B2 JP 6049621B2 JP 2013530348 A JP2013530348 A JP 2013530348A JP 2013530348 A JP2013530348 A JP 2013530348A JP 6049621 B2 JP6049621 B2 JP 6049621B2
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JP
Japan
Prior art keywords
analyte
liquid
capillary
elongated
channel
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JP2013530348A
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English (en)
Japanese (ja)
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JP2013537980A (ja
JP2013537980A5 (https=
Inventor
オキーフ、ドナルド
Original Assignee
ダ・ユー・エンタープライジズ、エルエルシー
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03B—SEPARATING SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS
    • B03B5/00—Washing granular, powdered or lumpy materials; Wet separating
    • B03B5/48—Washing granular, powdered or lumpy materials; Wet separating by mechanical classifiers
    • B03B5/52—Spiral classifiers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/22—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the construction of the column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34—Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6073—Construction of the column body in open tubular form
    • G01N30/6078—Capillaries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6086—Construction of the column body form designed to optimise dispersion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/80—Aspects related to sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J2220/84—Capillaries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2013530348A 2010-09-26 2011-09-23 分析物の分離 Expired - Fee Related JP6049621B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38651410P 2010-09-26 2010-09-26
US61/386,514 2010-09-26
PCT/US2011/052917 WO2012040555A1 (en) 2010-09-26 2011-09-23 Separation of analytes

Publications (3)

Publication Number Publication Date
JP2013537980A JP2013537980A (ja) 2013-10-07
JP2013537980A5 JP2013537980A5 (https=) 2014-11-06
JP6049621B2 true JP6049621B2 (ja) 2016-12-21

Family

ID=45874179

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013530348A Expired - Fee Related JP6049621B2 (ja) 2010-09-26 2011-09-23 分析物の分離

Country Status (7)

Country Link
US (1) US9821318B2 (https=)
EP (1) EP2618935B1 (https=)
JP (1) JP6049621B2 (https=)
CN (1) CN103108701B (https=)
AU (1) AU2011305254B2 (https=)
CA (1) CA2810805C (https=)
WO (1) WO2012040555A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103575622B (zh) * 2013-10-24 2015-11-25 中国石油大学(北京) 一种蜡分子扩散系数的测试方法
EP3118619A1 (en) * 2015-07-14 2017-01-18 Vrije Universiteit Brussel High-performance liquid chromatography with a vortex flow inducer
JP2018089576A (ja) * 2016-12-02 2018-06-14 東ソー株式会社 粒子分離装置
CN106596692B (zh) * 2017-01-14 2018-12-28 常州大学 一种弯曲毛细管电泳检测抗体多肽相互作用的方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5032283A (en) * 1983-03-03 1991-07-16 The Perkin Elmer Corporation Low dispersion fluid conduit useful in chromatography systems
DE3407065C2 (de) * 1983-03-03 1994-12-22 Perkin Elmer Corp Für Chromatographie-Vorrichtungen verwendbare Gas- oder Flüssigkeitsleitung mit niedriger Dispersion
DE68927019T2 (de) * 1988-04-29 1997-01-23 Beckman Instruments Inc Kassette mit einem kapillaren Detektor für Elektroforese
WO1996010170A1 (en) * 1994-09-29 1996-04-04 The Board Of Trustees Of The Leland Stanford Junior University Capillary-based separation methods for identifying bioactive analytes in a mixture
US5716852A (en) * 1996-03-29 1998-02-10 University Of Washington Microfabricated diffusion-based chemical sensor
US5772874A (en) 1995-11-02 1998-06-30 Cohesive Technologies, Inc. High performance liquid chromatography method and apparatus
US5948684A (en) * 1997-03-31 1999-09-07 University Of Washington Simultaneous analyte determination and reference balancing in reference T-sensor devices
US6063589A (en) * 1997-05-23 2000-05-16 Gamera Bioscience Corporation Devices and methods for using centripetal acceleration to drive fluid movement on a microfluidics system
DE69806499T2 (de) * 1997-11-12 2003-02-27 Pe Corp Ny Foster City Serpentinenförmiger elektroforetischer kanal mit selbstkorrigierenden kurven
CA2320296A1 (en) * 1998-05-18 1999-11-25 University Of Washington Liquid analysis cartridge
NZ511560A (en) * 1998-11-05 2002-11-26 Chemometec As A method for the assessment of particles and a system and a device for use in the method
US7011791B2 (en) * 2000-09-18 2006-03-14 University Of Washington Microfluidic devices for rotational manipulation of the fluidic interface between multiple flow streams
US20040224425A1 (en) 2003-05-08 2004-11-11 Gjerde Douglas T. Biomolecule open channel solid phase extraction systems and methods
US7111501B2 (en) * 2003-10-03 2006-09-26 Agilent Technologies, Inc. Devices and methods for separating constituents
JP2006090806A (ja) * 2004-09-22 2006-04-06 Yamatake Corp クロマトグラフ装置
TWI295730B (en) * 2004-11-25 2008-04-11 Ind Tech Res Inst Microfluidic chip for sample assay and method thereof
CA2505657A1 (en) * 2005-04-28 2006-10-28 York University Method for mixing inside a capillary and device for achieving same
US20070059781A1 (en) * 2005-09-15 2007-03-15 Ravi Kapur System for size based separation and analysis
SE529516C2 (sv) * 2005-10-24 2007-09-04 Alfa Laval Corp Ab Universell flödesmodul
US20070122819A1 (en) * 2005-11-25 2007-05-31 Industrial Technology Research Institute Analyte assay structure in microfluidic chip for quantitative analysis and method for using the same
KR100843339B1 (ko) * 2006-12-07 2008-07-03 한국전자통신연구원 혈액 중의 혈장 분리를 위하여 마이크로채널을 이용한혈장분리기 및 이에 의한 혈장분리방법
WO2009002580A2 (en) * 2007-04-02 2008-12-31 Boston Medical Center Corporation Method for bacterial lysis
WO2008130977A2 (en) * 2007-04-16 2008-10-30 The General Hospital Corporation D/B/A Massachusetts General Hospital Systems and methods for particle focusing in microchannels
WO2009038628A2 (en) * 2007-09-19 2009-03-26 Claros Diagnostics, Inc. Liquid containment for integrated assays
JP2009162664A (ja) * 2008-01-08 2009-07-23 Sony Corp 流路を用いた検出方法及び相互作用検出方法、並びに検出装置
US8641267B2 (en) 2008-04-14 2014-02-04 Agilent Technologies, Inc. Fluidic conduit with repeated disturbance of laminar flow

Also Published As

Publication number Publication date
AU2011305254A1 (en) 2013-03-14
CA2810805C (en) 2014-11-18
CN103108701A (zh) 2013-05-15
CN103108701B (zh) 2015-03-11
EP2618935A4 (en) 2015-10-28
US9821318B2 (en) 2017-11-21
WO2012040555A1 (en) 2012-03-29
US20130180894A1 (en) 2013-07-18
AU2011305254B2 (en) 2014-06-05
EP2618935B1 (en) 2018-11-07
CA2810805A1 (en) 2012-03-29
EP2618935A1 (en) 2013-07-31
JP2013537980A (ja) 2013-10-07

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