JP6040219B2 - 三叉神経因性痛に伴う疼痛の治療用タペンタドール - Google Patents

三叉神経因性痛に伴う疼痛の治療用タペンタドール Download PDF

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JP6040219B2
JP6040219B2 JP2014503020A JP2014503020A JP6040219B2 JP 6040219 B2 JP6040219 B2 JP 6040219B2 JP 2014503020 A JP2014503020 A JP 2014503020A JP 2014503020 A JP2014503020 A JP 2014503020A JP 6040219 B2 JP6040219 B2 JP 6040219B2
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tapentadol
pain
rats
cci
treatment
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Japanese (ja)
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JP2014510760A (ja
Inventor
クリストフ・トーマス
ドゥ・フリィ・ジャン
ツシェントケ・トーマス
ブロムス−フンケ・ペトラ
シーネ・クラウス
アモン・ミシェル
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グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2014503020A 2011-04-05 2012-04-03 三叉神経因性痛に伴う疼痛の治療用タペンタドール Expired - Fee Related JP6040219B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11002810 2011-04-05
EP11002810.7 2011-04-05
PCT/EP2012/001475 WO2012136351A1 (en) 2011-04-05 2012-04-03 Tapentadol for treating pain associated with trigeminal neuralgia

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016215836A Division JP6356763B2 (ja) 2011-04-05 2016-11-04 三叉神経因性痛に伴う疼痛の治療用タペンタドール

Publications (2)

Publication Number Publication Date
JP2014510760A JP2014510760A (ja) 2014-05-01
JP6040219B2 true JP6040219B2 (ja) 2016-12-07

Family

ID=44115674

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2014503020A Expired - Fee Related JP6040219B2 (ja) 2011-04-05 2012-04-03 三叉神経因性痛に伴う疼痛の治療用タペンタドール
JP2016215836A Expired - Fee Related JP6356763B2 (ja) 2011-04-05 2016-11-04 三叉神経因性痛に伴う疼痛の治療用タペンタドール

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016215836A Expired - Fee Related JP6356763B2 (ja) 2011-04-05 2016-11-04 三叉神経因性痛に伴う疼痛の治療用タペンタドール

Country Status (8)

Country Link
US (1) US20120309840A1 (https=)
EP (2) EP3607943B1 (https=)
JP (2) JP6040219B2 (https=)
ES (2) ES2761334T3 (https=)
HU (1) HUE047342T2 (https=)
PL (1) PL2694050T3 (https=)
PT (1) PT2694050T (https=)
WO (1) WO2012136351A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017052778A (ja) * 2011-04-05 2017-03-16 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 三叉神経因性痛に伴う疼痛の治療用タペンタドール

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2869981T3 (es) 2015-05-26 2021-10-26 Technophage Investig E Desenvolvimento Em Biotecnologia Sa Composiciones para su uso en el tratamiento de la enfermedad de parkinson y trastornos relacionados

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4426245A1 (de) 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
PE20030527A1 (es) 2001-10-24 2003-07-26 Gruenenthal Chemie Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen
CA2620202C (en) * 2005-08-26 2016-10-04 The Board Of Trustees Of The Leland Stanford Junior University Therapy procedure for drug delivery for trigeminal pain
DE102007012165A1 (de) 2007-03-12 2008-09-18 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie des Neuropathieschmerzes
EP1985292A1 (en) * 2007-04-23 2008-10-29 Grünenthal GmbH Titration of tapentadol
WO2010100477A2 (en) 2009-03-03 2010-09-10 Shire Llc Amino acid and peptide carbamate prodrugs of tapentadol and uses thereof
US20120309840A1 (en) * 2011-04-05 2012-12-06 Gruenenthal Gmbh Treatment of Pain Associated with Trigeminal Neuralgia

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017052778A (ja) * 2011-04-05 2017-03-16 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 三叉神経因性痛に伴う疼痛の治療用タペンタドール

Also Published As

Publication number Publication date
EP3607943A1 (en) 2020-02-12
PL2694050T3 (pl) 2020-03-31
ES2761334T3 (es) 2020-05-19
JP2014510760A (ja) 2014-05-01
JP2017052778A (ja) 2017-03-16
US20120309840A1 (en) 2012-12-06
JP6356763B2 (ja) 2018-07-11
EP3607943C0 (en) 2024-09-11
WO2012136351A1 (en) 2012-10-11
EP2694050B1 (en) 2019-10-02
EP2694050A1 (en) 2014-02-12
PT2694050T (pt) 2019-11-22
WO2012136351A8 (en) 2013-10-17
EP3607943B1 (en) 2024-09-11
ES2989433T3 (es) 2024-11-26
HUE047342T2 (hu) 2020-04-28

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