JP6031513B2 - 網赤血球の同定および測定 - Google Patents

網赤血球の同定および測定 Download PDF

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JP6031513B2
JP6031513B2 JP2014521678A JP2014521678A JP6031513B2 JP 6031513 B2 JP6031513 B2 JP 6031513B2 JP 2014521678 A JP2014521678 A JP 2014521678A JP 2014521678 A JP2014521678 A JP 2014521678A JP 6031513 B2 JP6031513 B2 JP 6031513B2
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red blood
cell
reticulocyte
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JP2014525040A (ja
JP2014525040A5 (enExample
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ザーニシャー、マイケル
ザーニシャー、ラッセル
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ロッシュ ダイアグノスティクス ヘマトロジー インコーポレイテッド
ロッシュ ダイアグノスティクス ヘマトロジー インコーポレイテッド
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • G01N15/1433Signal processing using image recognition
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/60Analysis of geometric attributes
    • G06T7/62Analysis of geometric attributes of area, perimeter, diameter or volume
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00Scenes; Scene-specific elements
    • G06V20/60Type of objects
    • G06V20/69Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/695Preprocessing, e.g. image segmentation
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04NPICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N7/00Television systems
    • H04N7/18Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012Red blood cells
    • G01N2015/014Reticulocytes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N2015/1472Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle with colour
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10024Color image
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30024Cell structures in vitro; Tissue sections in vitro
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30242Counting objects in image

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Multimedia (AREA)
  • Signal Processing (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Quality & Reliability (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Geometry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Image Processing (AREA)
  • Image Analysis (AREA)
JP2014521678A 2011-07-22 2012-07-13 網赤血球の同定および測定 Active JP6031513B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161510710P 2011-07-22 2011-07-22
US201161510614P 2011-07-22 2011-07-22
US61/510,614 2011-07-22
US61/510,710 2011-07-22
PCT/US2012/046787 WO2013016039A1 (en) 2011-07-22 2012-07-13 Identifying and measuring reticulocytes

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JP2014525040A JP2014525040A (ja) 2014-09-25
JP2014525040A5 JP2014525040A5 (enExample) 2015-05-21
JP6031513B2 true JP6031513B2 (ja) 2016-11-24

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US (2) US8964171B2 (enExample)
EP (1) EP2734828B1 (enExample)
JP (1) JP6031513B2 (enExample)
CN (1) CN103827658B (enExample)
AU (1) AU2012287304B2 (enExample)
CA (1) CA2842699A1 (enExample)
WO (1) WO2013016039A1 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9522396B2 (en) 2010-12-29 2016-12-20 S.D. Sight Diagnostics Ltd. Apparatus and method for automatic detection of pathogens
WO2012142496A1 (en) 2011-04-15 2012-10-18 Constitution Medical, Inc. Measuring volume and constituents of cells
US8792693B2 (en) 2011-07-09 2014-07-29 Gauss Surgical System and method for estimating extracorporeal blood volume in a physical sample
US10426356B2 (en) * 2011-07-09 2019-10-01 Gauss Surgical, Inc. Method for estimating a quantity of a blood component in a fluid receiver and corresponding error
US9870625B2 (en) * 2011-07-09 2018-01-16 Gauss Surgical, Inc. Method for estimating a quantity of a blood component in a fluid receiver and corresponding error
WO2013098821A1 (en) 2011-12-29 2013-07-04 Parasight Ltd. Methods and systems for detecting a pathogen in a biological sample
JP6021237B2 (ja) 2012-05-14 2016-11-09 ガウス サージカルGauss Surgical 患者の失血を管理するシステム
WO2013172874A1 (en) 2012-05-14 2013-11-21 Gauss Surgical System and method for estimating a quantity of a blood component in a fluid canister
JP5771635B2 (ja) * 2013-02-01 2015-09-02 株式会社Screenホールディングス キャリブレーション方法
US11020032B2 (en) * 2013-03-15 2021-06-01 Lars Otto LIEPOLD Fluid sampling apparatus and method
US20210334997A1 (en) * 2013-03-15 2021-10-28 Lars Otto LIEPOLD Fluid sampling apparatus and method
EP3869257B1 (en) 2013-05-23 2024-05-08 S.D. Sight Diagnostics Ltd. Method and system for imaging a cell sample
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for preparing a monolayer of cells, particularly suitable for diagnosis
EP3955042B1 (en) 2013-08-26 2024-08-21 S.D. Sight Diagnostics Ltd. Digital microscopy systems, methods and computer program products
US10482595B2 (en) 2014-08-27 2019-11-19 S.D. Sight Diagnostics Ltd. System and method for calculating focus variation for a digital microscope
WO2016076104A1 (ja) * 2014-11-13 2016-05-19 コニカミノルタ株式会社 画像処理方法、画像処理装置、及びプログラム
US10789710B2 (en) * 2015-05-15 2020-09-29 Gauss Surgical, Inc. Methods and systems for characterizing fluids from a patient
AU2016322966B2 (en) * 2015-09-17 2021-10-14 S.D. Sight Diagnostics Ltd Methods and apparatus for detecting an entity in a bodily sample
CN105572975B (zh) * 2016-03-24 2017-10-13 京东方科技集团股份有限公司 掩模板及光配向方法
WO2017168411A1 (en) 2016-03-30 2017-10-05 S.D. Sight Diagnostics Ltd Image processing device for identifying blood parasites
JP2017198631A (ja) * 2016-04-28 2017-11-02 アズビル株式会社 乾き度測定装置及び乾き度測定装置の測定誤差評価方法
CN109564209B (zh) 2016-05-11 2022-05-31 思迪赛特诊断有限公司 对样品实施的光学测量
US11307196B2 (en) 2016-05-11 2022-04-19 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
EP3532985B1 (en) 2016-10-28 2023-07-12 Beckman Coulter, Inc. Substance preparation evaluation system
CA3044226C (en) * 2016-11-18 2022-07-12 Siemens Healthcare Diagnostics Inc. Multiple sequential wavelength measurement of a liquid assay
EP3432194A1 (en) * 2017-07-16 2019-01-23 IMEC vzw Cell recognition
EP3710810B1 (en) 2017-11-14 2023-09-06 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
CN108469404B (zh) * 2018-02-01 2020-06-02 滨州学院 一种pm2.5浓度估算系统及方法
JP7254916B2 (ja) * 2018-10-26 2023-04-10 アボット ダイアベティス ケア インコーポレイテッド 生理学的パラメータ分析のための方法、デバイスおよびシステム
JP7677972B2 (ja) 2019-12-12 2025-05-15 エス.ディー.サイト ダイアグノスティックス リミテッド カラー血液スミア画像の人工的な生成
AU2020400401A1 (en) 2019-12-12 2022-06-02 S.D. Sight Diagnostics Ltd Analyzing an analyte disposed within a medium
CN111797742B (zh) * 2020-06-28 2024-04-19 扬州大学广陵学院 一种小麦胚乳蛋白体面积的测定方法
EP3978901A1 (en) * 2020-10-01 2022-04-06 Siemens Healthcare GmbH Maturity classification of stained reticulocytes using optical microscopy
CN113283353B (zh) * 2021-05-31 2022-04-01 创芯国际生物科技(广州)有限公司 一种基于显微图像的类器官细胞计数方法及系统
CN113552126A (zh) * 2021-07-23 2021-10-26 福州金域医学检验实验室有限公司 一种网织红细胞检测方法及其系统
CN119630955A (zh) * 2022-08-05 2025-03-14 贝克曼库尔特有限公司 利用成像对未成熟细胞类型的识别

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6040954A (ja) * 1984-04-04 1985-03-04 Hitachi Ltd 網赤血球自動算定装置
JPH02107964A (ja) * 1988-10-17 1990-04-19 Hitachi Ltd 網赤血球自動算定装置
JP3232145B2 (ja) 1991-12-27 2001-11-26 シスメックス株式会社 網赤血球測定方法
IL113805A0 (en) * 1994-05-23 1995-08-31 Coulter Corp Detection of reticulocytes
US6350613B1 (en) 1998-03-07 2002-02-26 Belton Dickinson & Co. Determination of white blood cell differential and reticulocyte counts
US6197593B1 (en) * 1998-10-20 2001-03-06 Coulter International Corp. Method for enumerating blood cells
US6784981B1 (en) 2000-06-02 2004-08-31 Idexx Laboratories, Inc. Flow cytometry-based hematology system
WO2002079749A2 (en) * 2001-03-28 2002-10-10 Inflamet Ltd. System and method for generating a profile of particulate components of a body fluid sample
GB0227160D0 (en) 2002-11-21 2002-12-24 Qinetiq Ltd Histological assessment of pleomorphism
US6955872B2 (en) 2003-03-20 2005-10-18 Coulter International Corp. Dye compositions which provide enhanced differential fluorescence and light scatter characteristics
US7483554B2 (en) 2003-11-17 2009-01-27 Aureon Laboratories, Inc. Pathological tissue mapping
US7689038B2 (en) 2005-01-10 2010-03-30 Cytyc Corporation Method for improved image segmentation
US7361510B2 (en) 2006-01-20 2008-04-22 Beckman Coulter, Inc. Methods of detection of iron deficiency
JP5010443B2 (ja) * 2006-12-20 2012-08-29 シスメックス株式会社 血球分析装置および血球分析方法
EP2147290B1 (en) * 2007-05-11 2017-08-02 CellSolutions, LLC Cell sample preparation method and apparatus
US7936913B2 (en) * 2007-08-07 2011-05-03 Nextslide Imaging Llc Network image review in clinical hematology
US7903241B2 (en) 2008-03-21 2011-03-08 Abbott Point Of Care, Inc. Method and apparatus for determining red blood cell indices of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells
CN102027369B (zh) * 2008-03-21 2018-10-26 艾博特健康公司 单独和在聚合凝块中检测和计数血小板的方法及设备
JP5082010B2 (ja) * 2008-03-21 2012-11-28 アボット ポイント オブ ケア インコーポレイテッド 赤血球中に含まれるヘモグロビンの固有色素を利用して血液試料のヘマトクリットを測定する方法及び装置
JP2012515931A (ja) * 2008-04-25 2012-07-12 ウィンケルマン、ジェイムズ 全血球数及び白血球百分率を決定するシステム及び方法
JP6348020B2 (ja) * 2014-08-29 2018-06-27 株式会社日立製作所 画像処理装置、画像処理方法およびそれを用いた検査方法。

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CA2842699A1 (en) 2013-01-31
CN103827658B (zh) 2016-04-13
US8964171B2 (en) 2015-02-24
US20150339813A1 (en) 2015-11-26
AU2012287304B2 (en) 2015-08-13
JP2014525040A (ja) 2014-09-25
CN103827658A (zh) 2014-05-28
AU2012287304A1 (en) 2013-05-02
EP2734828A1 (en) 2014-05-28
HK1193471A1 (zh) 2014-09-19
EP2734828B1 (en) 2019-12-18
US20130023007A1 (en) 2013-01-24
WO2013016039A1 (en) 2013-01-31

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