JP6018081B2 - 自己免疫および炎症性疾患におけるリンパ系内投与用の脂肪由来間葉系幹細胞 - Google Patents
自己免疫および炎症性疾患におけるリンパ系内投与用の脂肪由来間葉系幹細胞 Download PDFInfo
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- JP6018081B2 JP6018081B2 JP2013548903A JP2013548903A JP6018081B2 JP 6018081 B2 JP6018081 B2 JP 6018081B2 JP 2013548903 A JP2013548903 A JP 2013548903A JP 2013548903 A JP2013548903 A JP 2013548903A JP 6018081 B2 JP6018081 B2 JP 6018081B2
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
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- A—HUMAN NECESSITIES
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- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
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- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Developmental Biology & Embryology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Mycology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11250025 | 2011-01-12 | ||
| EP11250025.1 | 2011-01-12 | ||
| PCT/IB2012/000097 WO2012095743A2 (en) | 2011-01-12 | 2012-01-12 | Methods and compositions for use in intralymphatic cellular therapies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016190665A Division JP2017035094A (ja) | 2011-01-12 | 2016-09-29 | 自己免疫および炎症性疾患におけるリンパ系内投与用の脂肪由来間葉系幹細胞 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014502628A JP2014502628A (ja) | 2014-02-03 |
| JP2014502628A5 JP2014502628A5 (enExample) | 2015-03-05 |
| JP6018081B2 true JP6018081B2 (ja) | 2016-11-02 |
Family
ID=45558792
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013548903A Expired - Fee Related JP6018081B2 (ja) | 2011-01-12 | 2012-01-12 | 自己免疫および炎症性疾患におけるリンパ系内投与用の脂肪由来間葉系幹細胞 |
| JP2016190665A Pending JP2017035094A (ja) | 2011-01-12 | 2016-09-29 | 自己免疫および炎症性疾患におけるリンパ系内投与用の脂肪由来間葉系幹細胞 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016190665A Pending JP2017035094A (ja) | 2011-01-12 | 2016-09-29 | 自己免疫および炎症性疾患におけるリンパ系内投与用の脂肪由来間葉系幹細胞 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140154274A1 (enExample) |
| EP (1) | EP2663316A2 (enExample) |
| JP (2) | JP6018081B2 (enExample) |
| KR (1) | KR101900664B1 (enExample) |
| ES (1) | ES2479544T1 (enExample) |
| WO (1) | WO2012095743A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| SG10202001007TA (en) | 2005-09-23 | 2020-03-30 | Tigenix Sau | Cell populations having immunoregulatory activity, method for isolation and uses |
| US20160120910A1 (en) * | 2013-06-25 | 2016-05-05 | Tigenix S.A.U. | Cell populations having immunoregulatory activity, methods for the preparation and uses thereof |
| US20150104470A1 (en) * | 2013-10-11 | 2015-04-16 | Neil H. Riordan | Immune modulation by peri-lymphatic or intra-lymphatic cell therapy |
| US20170121685A1 (en) * | 2015-11-02 | 2017-05-04 | Tigenix S.A.U. | Mesenchymal stem cell-derived exosomes and their uses |
| GB201604304D0 (en) | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| KR20190018420A (ko) * | 2016-05-06 | 2019-02-22 | 각코우호징 오사카 이카야쿠카 다이가쿠 | 염증성 질환 치료용 줄기세포의 기능 강화를 위한 스타틴 봉입 나노입자 제제, 및 이를 함유하는 염증성 질환 치료용 기능 강화 줄기세포 |
| JP6788003B2 (ja) * | 2016-08-26 | 2020-11-18 | 学校法人大阪医科薬科大学 | スタチン封入ナノ粒子を含有する機能増強幹細胞を含む炎症性疾患治療用細胞製剤 |
| WO2021075525A1 (ja) | 2019-10-17 | 2021-04-22 | テルモ株式会社 | 炎症性疾患を処置するための細胞培養物 |
| WO2021207192A1 (en) * | 2020-04-08 | 2021-10-14 | Figene, Llc | Methods and compositions for allergy and asthma treatment using fibroblasts |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9694038B2 (en) * | 2000-04-06 | 2017-07-04 | Wayne P. Franco | Combination growth factor therapy and cell therapy for treatment of acute and chronic diseases of the organs |
| US20040115216A1 (en) * | 2002-07-12 | 2004-06-17 | The Johns Hopkins University | Reagents and methods for engaging unique clonotypic lymphocyte receptors |
| CA2564679C (en) * | 2004-03-22 | 2015-06-23 | Osiris Therapeutics, Inc. | Mesenchymal stem cells and uses therefor |
| WO2005097147A1 (en) * | 2004-03-30 | 2005-10-20 | Boston Scientific Limited (Incorporated In Ireland) | Restenosis therapy using mesenchymal stem cells |
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| SG10202001007TA (en) * | 2005-09-23 | 2020-03-30 | Tigenix Sau | Cell populations having immunoregulatory activity, method for isolation and uses |
| EP2303293A1 (en) * | 2008-05-27 | 2011-04-06 | Pluristem Ltd. | Methods of treating inflammatory colon diseases |
| GB0814249D0 (en) * | 2008-08-04 | 2008-09-10 | Cellerix Sa | Uses of mesenchymal stem cells |
| CN107090437A (zh) * | 2009-03-06 | 2017-08-25 | 国立大学法人三重大学 | 用于增强t细胞功能的方法 |
| HUE031921T2 (en) * | 2009-07-09 | 2017-08-28 | Tigenix S A U | Methods and preparations for use in cell therapy |
| WO2011047345A2 (en) * | 2009-10-15 | 2011-04-21 | Tai June Yoo | Methods of treating diseases of conditions using mesenchymal stem cells |
-
2012
- 2012-01-12 JP JP2013548903A patent/JP6018081B2/ja not_active Expired - Fee Related
- 2012-01-12 WO PCT/IB2012/000097 patent/WO2012095743A2/en not_active Ceased
- 2012-01-12 KR KR1020137021276A patent/KR101900664B1/ko not_active Expired - Fee Related
- 2012-01-12 US US13/979,308 patent/US20140154274A1/en not_active Abandoned
- 2012-01-12 EP EP12701941.2A patent/EP2663316A2/en not_active Ceased
- 2012-01-12 ES ES12701941.2T patent/ES2479544T1/es active Pending
-
2016
- 2016-09-29 JP JP2016190665A patent/JP2017035094A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR101900664B1 (ko) | 2018-09-21 |
| WO2012095743A3 (en) | 2012-11-01 |
| JP2014502628A (ja) | 2014-02-03 |
| WO2012095743A2 (en) | 2012-07-19 |
| EP2663316A2 (en) | 2013-11-20 |
| ES2479544T1 (es) | 2014-08-20 |
| JP2017035094A (ja) | 2017-02-16 |
| US20140154274A1 (en) | 2014-06-05 |
| KR20140127139A (ko) | 2014-11-03 |
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