JP6017136B2 - Jak2核酸中の変異を検出するための組成物および方法 - Google Patents
Jak2核酸中の変異を検出するための組成物および方法 Download PDFInfo
- Publication number
- JP6017136B2 JP6017136B2 JP2011534635A JP2011534635A JP6017136B2 JP 6017136 B2 JP6017136 B2 JP 6017136B2 JP 2011534635 A JP2011534635 A JP 2011534635A JP 2011534635 A JP2011534635 A JP 2011534635A JP 6017136 B2 JP6017136 B2 JP 6017136B2
- Authority
- JP
- Japan
- Prior art keywords
- jak2
- nucleic acid
- seq
- mutation
- mutations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/10—Protein-tyrosine kinases (2.7.10)
- C12Y207/10001—Receptor protein-tyrosine kinase (2.7.10.1)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/22—Haematology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11050108P | 2008-10-31 | 2008-10-31 | |
| US61/110,501 | 2008-10-31 | ||
| US12/503,318 | 2009-07-15 | ||
| US12/503,318 US20100112571A1 (en) | 2008-10-31 | 2009-07-15 | Compositions and methods for detecting mutations in jak2 nucleic acid |
| PCT/US2009/061691 WO2010051214A1 (en) | 2008-10-31 | 2009-10-22 | Compositions and methods for detecting mutations in jak2 nucleic acid |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014227524A Division JP6145083B2 (ja) | 2008-10-31 | 2014-11-07 | Jak2核酸中の変異を検出するための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012507291A JP2012507291A (ja) | 2012-03-29 |
| JP2012507291A5 JP2012507291A5 (enExample) | 2012-11-29 |
| JP6017136B2 true JP6017136B2 (ja) | 2016-10-26 |
Family
ID=42129212
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011534635A Active JP6017136B2 (ja) | 2008-10-31 | 2009-10-22 | Jak2核酸中の変異を検出するための組成物および方法 |
| JP2014227524A Active JP6145083B2 (ja) | 2008-10-31 | 2014-11-07 | Jak2核酸中の変異を検出するための組成物および方法 |
| JP2016229813A Pending JP2017070296A (ja) | 2008-10-31 | 2016-11-28 | Jak2核酸中の変異を検出するための組成物および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014227524A Active JP6145083B2 (ja) | 2008-10-31 | 2014-11-07 | Jak2核酸中の変異を検出するための組成物および方法 |
| JP2016229813A Pending JP2017070296A (ja) | 2008-10-31 | 2016-11-28 | Jak2核酸中の変異を検出するための組成物および方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20100112571A1 (enExample) |
| EP (4) | EP3093350B1 (enExample) |
| JP (3) | JP6017136B2 (enExample) |
| WO (1) | WO2010051214A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8512948B2 (en) | 2008-10-31 | 2013-08-20 | Quest Diagnostics Investments Incorporated | Compositions and methods for detecting mutations in JAK2 nucleic acid |
| US20100112571A1 (en) * | 2008-10-31 | 2010-05-06 | Quest Diagnostics Investments Incorporated | Compositions and methods for detecting mutations in jak2 nucleic acid |
| WO2014068072A1 (en) * | 2012-10-31 | 2014-05-08 | Institut Gustave-Roussy | Identification, assessment and therapy of essential thrombocythemia with resistance to jak2 inhibitors |
| CN108283013B (zh) * | 2015-07-24 | 2020-10-30 | 公立大学法人名古屋市立大学 | 骨髓纤维症的诊断和预后辅助及治疗效果监测方法及装置 |
| US20220282314A1 (en) * | 2019-08-30 | 2022-09-08 | Toyo Kohan Co., Ltd. | Kit for evaluating a gene mutation related to myeloproliferative neoplasms |
| JP7456739B2 (ja) * | 2019-08-30 | 2024-03-27 | 東洋鋼鈑株式会社 | 骨髄増殖性腫瘍に関連する遺伝子変異評価用キット |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5639611A (en) * | 1988-12-12 | 1997-06-17 | City Of Hope | Allele specific polymerase chain reaction |
| EP1482049A3 (en) * | 1990-11-28 | 2004-12-15 | Ludwig Institute For Cancer Research | A protein tyrosine kinase. |
| US20030092019A1 (en) * | 2001-01-09 | 2003-05-15 | Millennium Pharmaceuticals, Inc. | Methods and compositions for diagnosing and treating neuropsychiatric disorders such as schizophrenia |
| US7447594B2 (en) * | 2001-07-10 | 2008-11-04 | Ocimum Biosolutions, Inc. | Molecular cardiotoxicology modeling |
| CN1477703A (zh) * | 2002-08-02 | 2004-02-25 | ǧס������ҵ��ʽ���� | 焊球组件及其生产方法,形成焊块的方法 |
| WO2007038215A1 (en) * | 2005-09-22 | 2007-04-05 | Incyte Corporation | Tetracyclic inhibitors of janus kinases |
| US20070224598A1 (en) * | 2006-03-15 | 2007-09-27 | The Methodist Hospital Research Institute | System and method for detection of mutations in JAK2 polynucleotides |
| US20070248961A1 (en) * | 2006-04-20 | 2007-10-25 | Maher Albitar | Methods for detecting mutations in JAK2 nucleic acid |
| US20100112571A1 (en) * | 2008-10-31 | 2010-05-06 | Quest Diagnostics Investments Incorporated | Compositions and methods for detecting mutations in jak2 nucleic acid |
-
2009
- 2009-07-15 US US12/503,318 patent/US20100112571A1/en not_active Abandoned
- 2009-10-22 EP EP16158591.4A patent/EP3093350B1/en active Active
- 2009-10-22 EP EP19180822.9A patent/EP3572530B1/en active Active
- 2009-10-22 EP EP09824031.0A patent/EP2340315B1/en active Active
- 2009-10-22 JP JP2011534635A patent/JP6017136B2/ja active Active
- 2009-10-22 WO PCT/US2009/061691 patent/WO2010051214A1/en not_active Ceased
- 2009-10-22 EP EP14161006.3A patent/EP2770066B1/en active Active
-
2014
- 2014-11-07 JP JP2014227524A patent/JP6145083B2/ja active Active
-
2016
- 2016-11-28 JP JP2016229813A patent/JP2017070296A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010051214A1 (en) | 2010-05-06 |
| EP2340315A4 (en) | 2012-04-25 |
| EP3572530B1 (en) | 2023-03-01 |
| EP2340315A1 (en) | 2011-07-06 |
| JP2012507291A (ja) | 2012-03-29 |
| EP2770066B1 (en) | 2016-03-09 |
| EP3093350B1 (en) | 2019-06-19 |
| EP2770066A3 (en) | 2014-09-03 |
| EP2770066A2 (en) | 2014-08-27 |
| EP3093350A3 (en) | 2017-03-15 |
| US20100112571A1 (en) | 2010-05-06 |
| EP2340315B1 (en) | 2014-03-26 |
| JP2015061531A (ja) | 2015-04-02 |
| JP2017070296A (ja) | 2017-04-13 |
| EP3572530A3 (en) | 2020-02-26 |
| WO2010051214A8 (en) | 2013-06-06 |
| EP3572530A2 (en) | 2019-11-27 |
| EP3093350A2 (en) | 2016-11-16 |
| JP6145083B2 (ja) | 2017-06-07 |
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