JP6010037B2 - 腫瘍浸潤全tリンパ球の分析に基づいて、がん患者の生存指標を測定する方法 - Google Patents

腫瘍浸潤全tリンパ球の分析に基づいて、がん患者の生存指標を測定する方法 Download PDF

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JP6010037B2
JP6010037B2 JP2013532230A JP2013532230A JP6010037B2 JP 6010037 B2 JP6010037 B2 JP 6010037B2 JP 2013532230 A JP2013532230 A JP 2013532230A JP 2013532230 A JP2013532230 A JP 2013532230A JP 6010037 B2 JP6010037 B2 JP 6010037B2
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cancer
otl
tumor
cells
analysis
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JP2013544502A (ja
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オレク,スフェン
シュバッハウラ,ティム
バロン,ウド
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エピオンティス ゲーエムベーハー
エピオンティス ゲーエムベーハー
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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JP2013532230A 2010-10-08 2011-10-10 腫瘍浸潤全tリンパ球の分析に基づいて、がん患者の生存指標を測定する方法 Expired - Fee Related JP6010037B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10187046 2010-10-08
EP10187046.7 2010-10-08
PCT/EP2011/067660 WO2012045888A1 (en) 2010-10-08 2011-10-10 Method for determining cancer patient survival based on analyzing tumor-infiltrating overall t-lymphocytes

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JP2013544502A JP2013544502A (ja) 2013-12-19
JP2013544502A5 JP2013544502A5 (enExample) 2014-11-27
JP6010037B2 true JP6010037B2 (ja) 2016-10-19

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US (1) US20130260378A1 (enExample)
EP (1) EP2625288B1 (enExample)
JP (1) JP6010037B2 (enExample)
CA (1) CA2814150A1 (enExample)
WO (1) WO2012045888A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201221133D0 (en) 2012-11-23 2013-01-09 Epiontis Gmbh Epigenetic method for the identification of subpopulations of CD8 and T lympocytes, in particular CD8 alpha and beta T lymphocytes
GB201516971D0 (en) * 2015-09-25 2015-11-11 Epiontis Gmbh MVD as epigenetic marker for the identification of immune cells, in particular CD56+ NK cells
GB201516972D0 (en) * 2015-09-25 2015-11-11 Epiontis Gmbh LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells
DE102016005947B3 (de) * 2016-05-16 2017-06-08 Dimo Dietrich Verfahren zur Abschätzung der Prognose und zur Prädiktion des Ansprechens auf eine Immuntherapie von Patienten mit malignen Erkrankungen
US11685955B2 (en) 2016-05-16 2023-06-27 Dimo Dietrich Method for predicting response of patients with malignant diseases to immunotherapy
JP7061342B2 (ja) * 2018-03-14 2022-04-28 学校法人 愛知医科大学 エフェクター制御性t細胞の検出及び調製
DE102018116353B4 (de) * 2018-07-05 2020-06-10 Epiontis Gmbh Verfahren zum Nachweis und zur Zählung epigenetischer Immunzellen in humanen Blutproben für Immundiagnostik und Neugeborenen-Screening
WO2021077063A1 (en) * 2019-10-18 2021-04-22 Washington University Methods and systems for measuring cell states
WO2024254366A1 (en) 2023-06-09 2024-12-12 Dow Global Technologies Llc Method for producing corrugated laminated panels

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002171973A (ja) 2000-12-07 2002-06-18 Univ Tokyo Dnaメチル化パターンによる細胞の同定法
AU2003285586A1 (en) 2002-12-03 2004-06-23 Medical Research Council Regulatory t-cells
EP1777523A1 (en) * 2005-10-19 2007-04-25 INSERM (Institut National de la Santé et de la Recherche Médicale) An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method
DK1826279T3 (da) 2006-02-28 2011-09-05 Charite Universitaetsmedizin Detektering og kvalitetskontrol af regulatoriske t-celler vha. DNA-metyleringsanalyse af FoxP3--genet
EP2141245A1 (en) * 2008-07-03 2010-01-06 Ivana Türbachova DNA methylation analysis of regulatory T cells through DNA-methylation analysis of the TSDR region of the gene foxP3
DK2199411T3 (en) * 2008-12-16 2015-08-03 Epiontis Gmbh Epigenetic markers for the identification of CD3-positive T lymphocytes

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CA2814150A1 (en) 2012-04-12
EP2625288B1 (en) 2016-05-25
JP2013544502A (ja) 2013-12-19
WO2012045888A1 (en) 2012-04-12
US20130260378A1 (en) 2013-10-03
EP2625288A1 (en) 2013-08-14

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