JP5933451B2 - 組換えｎｄｖ抗原及びその使用 - Google Patents

組換えｎｄｖ抗原及びその使用 Download PDF

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Publication number
JP5933451B2
JP5933451B2 JP2012546255A JP2012546255A JP5933451B2 JP 5933451 B2 JP5933451 B2 JP 5933451B2 JP 2012546255 A JP2012546255 A JP 2012546255A JP 2012546255 A JP2012546255 A JP 2012546255A JP 5933451 B2 JP5933451 B2 JP 5933451B2
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ndv
polypeptide
sequence
antigen
protein
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JP2013515747A5 (enExample
JP2013515747A (ja
Inventor
シュアン グオ
シュアン グオ
カロライン マリー トロウペ
カロライン マリー トロウペ
ブラッドリー ジェイ． フェイルメイヤー
ブラッドリー ジェイ． フェイルメイヤー
ジョイス アニータ プリッチャード
ジョイス アニータ プリッチャード
ジュリオ セルジオ クルズ−コイ
ジュリオ セルジオ クルズ−コイ
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Merial Ltd
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Merial Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/517—Plant cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2012546255A 2009-12-28 2010-12-28 組換えｎｄｖ抗原及びその使用 Active JP5933451B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29029709P 2009-12-28 2009-12-28
US61/290,297 2009-12-28
PCT/US2010/062209 WO2011090708A2 (en) 2009-12-28 2010-12-28 Recombinant ndv antigen and uses thereof

Publications (3)

Publication Number Publication Date
JP2013515747A JP2013515747A (ja) 2013-05-09
JP2013515747A5 JP2013515747A5 (enExample) 2014-01-30
JP5933451B2 true JP5933451B2 (ja) 2016-06-08

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JP2012546255A Active JP5933451B2 (ja) 2009-12-28 2010-12-28 組換えｎｄｖ抗原及びその使用

Country Status (11)

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US (1) US10633667B2 (enExample)
EP (2) EP2519258B1 (enExample)
JP (1) JP5933451B2 (enExample)
KR (1) KR20120101572A (enExample)
CN (1) CN103260643A (enExample)
AR (2) AR079767A1 (enExample)
CA (1) CA2785653C (enExample)
DO (1) DOP2012000187A (enExample)
MX (1) MX351643B (enExample)
PE (1) PE20121685A1 (enExample)
WO (1) WO2011090708A2 (enExample)

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CN107746869A (zh) * 2009-12-28 2018-03-02 赛诺菲疫苗技术公司 微藻中异源多肽的生产，微藻胞外体、组合物及其制备方法和用途
KR20140033096A (ko) * 2011-05-07 2014-03-17 래보래토리오 아비-멕스, 에스.에이. 데 씨.브이. 바이러스성 벡터를 이용한 prrs에 대한 재조합 백신
US9358283B2 (en) 2011-10-28 2016-06-07 The Regents Of The University Of California Diatom-based vaccines
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EP2660323A1 (en) * 2012-05-02 2013-11-06 Algenics Production of secreted therapeutic antibodies in phaeodactylum tricornutum microalgae
EP2671950A1 (de) * 2012-06-06 2013-12-11 Philipps-Universität Marburg Expression und Sekretion von rekombinanten, vollständig assemblierten Proteinkomplexen durch Mikroalgen
CN105695491B (zh) * 2014-05-09 2020-01-10 中国农业科学院生物技术研究所 鸡新城疫糖蛋白病毒抗原的制备方法及其产品
CN105567715B (zh) * 2014-10-17 2021-06-29 丰益(上海)生物技术研发中心有限公司 裂殖壶菌α-微管蛋白相关序列及其应用
WO2016073739A1 (en) * 2014-11-05 2016-05-12 Research Institute At Nationwide Children's Hospital Methods and materials for producing recombinant viruses in eukaryotic microalgae
US10196616B2 (en) * 2017-02-15 2019-02-05 The United States Of America, As Represented By The Secretary Of Agriculture Altered avian virus for in-ovo inoculation and methods of use thereof
CN107099513B (zh) * 2017-06-22 2020-07-14 北京邦卓生物科技有限公司 一种共表达ndv hn和ibdv vp2基因的hvt的构建及其应用
CN113652406B (zh) * 2021-09-01 2023-05-02 青岛易邦生物工程有限公司 一种鸡传染性喉气管炎重组病毒株及其应用
CN119020301A (zh) * 2024-08-14 2024-11-26 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 一种新城疫m1n毒株及改造方法和重组疫苗制备方法

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Publication number Publication date
CA2785653C (en) 2018-05-01
AR122325A2 (es) 2022-08-31
WO2011090708A2 (en) 2011-07-28
CN103260643A (zh) 2013-08-21
KR20120101572A (ko) 2012-09-13
PE20121685A1 (es) 2012-12-28
WO2011090708A3 (en) 2011-12-15
CA2785653A1 (en) 2011-07-28
EP3213766A1 (en) 2017-09-06
US10633667B2 (en) 2020-04-28
MX351643B (es) 2017-10-23
AR079767A1 (es) 2012-02-15
US20110162115A1 (en) 2011-06-30
EP2519258B1 (en) 2017-07-26
MX2012007545A (es) 2012-11-12
DOP2012000187A (es) 2012-12-15
EP2519258A2 (en) 2012-11-07
JP2013515747A (ja) 2013-05-09

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