JP5912218B2 - 抗細菌性細胞外多糖溶媒和系 - Google Patents

抗細菌性細胞外多糖溶媒和系 Download PDF

Info

Publication number
JP5912218B2
JP5912218B2 JP2009510146A JP2009510146A JP5912218B2 JP 5912218 B2 JP5912218 B2 JP 5912218B2 JP 2009510146 A JP2009510146 A JP 2009510146A JP 2009510146 A JP2009510146 A JP 2009510146A JP 5912218 B2 JP5912218 B2 JP 5912218B2
Authority
JP
Japan
Prior art keywords
acid
biofilm
pharmaceutical composition
metal ion
bacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2009510146A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009536666A5 (enExample
JP2009536666A (ja
Inventor
ミュンティ，マシュー・エフ
オリバー，ダナ・エイ
ルイス，セシル・オー
Original Assignee
メドトロニック・ゾーメド・インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/431,495 external-priority patent/US20070264296A1/en
Application filed by メドトロニック・ゾーメド・インコーポレーテッド filed Critical メドトロニック・ゾーメド・インコーポレーテッド
Publication of JP2009536666A publication Critical patent/JP2009536666A/ja
Publication of JP2009536666A5 publication Critical patent/JP2009536666A5/ja
Application granted granted Critical
Publication of JP5912218B2 publication Critical patent/JP5912218B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/22—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/40—Peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009510146A 2006-05-10 2007-05-08 抗細菌性細胞外多糖溶媒和系 Expired - Fee Related JP5912218B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11/431,495 US20070264296A1 (en) 2006-05-10 2006-05-10 Biofilm extracellular polysachharide solvating system
US11/431,495 2006-05-10
US11/739,508 2007-04-24
US11/739,508 US7976873B2 (en) 2006-05-10 2007-04-24 Extracellular polysaccharide solvating system for treatment of bacterial ear conditions
PCT/US2007/068477 WO2007134055A1 (en) 2006-05-10 2007-05-08 Antibacterial extracellular polysaccharide solvating system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014173789A Division JP2014240419A (ja) 2006-05-10 2014-08-28 抗細菌性細胞外多糖溶媒和系

Publications (3)

Publication Number Publication Date
JP2009536666A JP2009536666A (ja) 2009-10-15
JP2009536666A5 JP2009536666A5 (enExample) 2010-06-24
JP5912218B2 true JP5912218B2 (ja) 2016-04-27

Family

ID=38458463

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009510146A Expired - Fee Related JP5912218B2 (ja) 2006-05-10 2007-05-08 抗細菌性細胞外多糖溶媒和系
JP2014173789A Pending JP2014240419A (ja) 2006-05-10 2014-08-28 抗細菌性細胞外多糖溶媒和系

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014173789A Pending JP2014240419A (ja) 2006-05-10 2014-08-28 抗細菌性細胞外多糖溶媒和系

Country Status (9)

Country Link
US (1) US7976873B2 (enExample)
EP (1) EP2029232B1 (enExample)
JP (2) JP5912218B2 (enExample)
KR (1) KR101453011B1 (enExample)
CN (1) CN104815328A (enExample)
AU (1) AU2007249413B2 (enExample)
CA (1) CA2651646C (enExample)
ES (1) ES2650974T3 (enExample)
WO (1) WO2007134055A1 (enExample)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009525284A (ja) * 2006-01-30 2009-07-09 タイタン ファーマシューティカルズ インコーポレイテッド バイオフィルム関連感染を処置するためのガリウムの使用
US7993675B2 (en) 2006-05-10 2011-08-09 Medtronic Xomed, Inc. Solvating system and sealant for medical use in the sinuses and nasal passages
US20070264296A1 (en) 2006-05-10 2007-11-15 Myntti Matthew F Biofilm extracellular polysachharide solvating system
US7959943B2 (en) 2006-05-10 2011-06-14 Medtronics Xomed, Inc. Solvating system and sealant for medical use in the middle or inner ear
US7976873B2 (en) 2006-05-10 2011-07-12 Medtronic Xomed, Inc. Extracellular polysaccharide solvating system for treatment of bacterial ear conditions
US8088095B2 (en) 2007-02-08 2012-01-03 Medtronic Xomed, Inc. Polymeric sealant for medical use
GB2463181B (en) 2007-05-14 2013-03-27 Univ New York State Res Found Induction of a physiological dispersion response in bacterial cells in a biofilm
US20090054881A1 (en) * 2007-06-14 2009-02-26 Yosef Krespi Mammalian biofilm treatment processes and instruments
CA2727432C (en) * 2008-06-12 2016-10-11 Medtronic Xomed, Inc. Method for treating chronic wounds with an extracellular polymeric substance solvating system
US20100086576A1 (en) * 2008-10-06 2010-04-08 Myntti Matthew F Antimicrobial composition and methods of making and using same
DE102008064481A1 (de) * 2008-12-18 2010-08-12 Bode Chemie Gmbh Kombinierte Desinfektions- und Dekontaminationsmittel mit erhöhter Wirksamkeit
EP2706845B1 (en) 2011-05-10 2021-06-23 Next Science IP Holdings Pty Ltd Antimicrobial solid and methods of making and using same
CA3254125A1 (en) 2011-10-08 2025-07-08 Next Science IP Holdings Pty Ltd Antimicrobial compositions and methods employing same
CN103987664B (zh) 2011-12-06 2017-03-08 德尔塔阀门公司 龙头中的臭氧分配
US9707520B2 (en) 2012-01-18 2017-07-18 Nch Corporation Composition, system, and method for treating water systems
EP2807323B1 (en) 2012-01-18 2020-05-13 NCH Corporation Composition and method for treating water systems
US9716253B2 (en) * 2012-03-23 2017-07-25 Lg Chem, Ltd. Battery case for secondary battery
CN103484392A (zh) * 2012-06-13 2014-01-01 中国海洋大学 用Pseudomonas fluorescens PGM37菌株生产葡甘聚糖
JP6430490B2 (ja) 2013-05-02 2018-11-28 ネクスト サイエンス アイピー ホールディングス ピーティワイ エルティーディ １以上の有機溶媒を含む高い浸透性の抗菌性組成物
US9192574B2 (en) 2013-10-24 2015-11-24 Medtronic Xomed, Inc. Chitosan paste wound dressing
US9192692B2 (en) 2013-10-24 2015-11-24 Medtronic Xomed, Inc. Chitosan stenting paste
US9506016B2 (en) 2013-11-06 2016-11-29 Nch Corporation Composition and method for treating water systems
US9441190B2 (en) 2013-11-06 2016-09-13 Nch Corporation Composition and method for treating water systems
US9848604B2 (en) * 2014-07-11 2017-12-26 Medtronic Xomed, Inc. Antimicrobial wash
US9744192B2 (en) 2015-03-16 2017-08-29 Lee A. Flippin Methods of treating chronic rhinosinusitis
CN107920532A (zh) 2015-07-17 2018-04-17 贴近科学Ip控股私人有限公司 具有抗内生孢子功效的抗微生物组合物
BR112018002548A2 (pt) 2015-08-07 2018-09-18 Next Science IP Holdings Pty Ltd composição antimicrobiana com eficácia contra endoesporos
CN115093008B (zh) 2015-12-21 2024-05-14 德尔塔阀门公司 包括消毒装置的流体输送系统
CN105770999B (zh) * 2016-03-03 2019-01-29 宁夏大学 一种消除细菌生物被膜的复合生物材料
CA3029601A1 (en) * 2016-06-30 2018-01-04 Next Science IP Holdings Pty Ltd Antimicrobial compositions and methods employing same
EP3710030A4 (en) 2017-11-19 2020-12-23 Next Science IP Holdings Pty Ltd COMPOSITIONS AND METHODS FOR TREATMENT OF INTERVERTEBRAL DISCS
WO2019213396A1 (en) * 2018-05-03 2019-11-07 Jaim Nulman Formulations and delivery methods for reduction and elimination of pathogen induced inflammations in the human body
US11819229B2 (en) 2019-06-19 2023-11-21 Boston Scientific Scimed, Inc. Balloon surface photoacoustic pressure wave generation to disrupt vascular lesions
US12402946B2 (en) 2019-06-19 2025-09-02 Boston Scientific Scimed, Inc. Breakdown of laser pulse energy for breakup of vascular calcium
US11717139B2 (en) 2019-06-19 2023-08-08 Bolt Medical, Inc. Plasma creation via nonaqueous optical breakdown of laser pulse energy for breakup of vascular calcium
US11660427B2 (en) 2019-06-24 2023-05-30 Boston Scientific Scimed, Inc. Superheating system for inertial impulse generation to disrupt vascular lesions
US12280223B2 (en) 2019-06-26 2025-04-22 Boston Scientific Scimed, Inc. Focusing element for plasma system to disrupt vascular lesions
US11583339B2 (en) 2019-10-31 2023-02-21 Bolt Medical, Inc. Asymmetrical balloon for intravascular lithotripsy device and method
US12102384B2 (en) 2019-11-13 2024-10-01 Bolt Medical, Inc. Dynamic intravascular lithotripsy device with movable energy guide
US12274497B2 (en) 2019-12-18 2025-04-15 Bolt Medical, Inc. Multiplexer for laser-driven intravascular lithotripsy device
CN115426990A (zh) * 2020-01-24 2022-12-02 斯皮拉尔诊疗有限公司 通过鼓膜进入中耳和内耳的微创工具和方法
US12446961B2 (en) 2020-02-10 2025-10-21 Bolt Medical, Inc. System and method for pressure monitoring within a catheter system
US11672599B2 (en) 2020-03-09 2023-06-13 Bolt Medical, Inc. Acoustic performance monitoring system and method within intravascular lithotripsy device
US20210290286A1 (en) 2020-03-18 2021-09-23 Bolt Medical, Inc. Optical analyzer assembly and method for intravascular lithotripsy device
US11707323B2 (en) 2020-04-03 2023-07-25 Bolt Medical, Inc. Electrical analyzer assembly for intravascular lithotripsy device
US12295654B2 (en) 2020-06-03 2025-05-13 Boston Scientific Scimed, Inc. System and method for maintaining balloon integrity within intravascular lithotripsy device with plasma generator
US12207870B2 (en) 2020-06-15 2025-01-28 Boston Scientific Scimed, Inc. Spectroscopic tissue identification for balloon intravascular lithotripsy guidance
CA3198601A1 (en) 2020-10-14 2022-04-21 Next Science IP Holdings Pty Ltd Hard surface disinfecting composition
US12016610B2 (en) 2020-12-11 2024-06-25 Bolt Medical, Inc. Catheter system for valvuloplasty procedure
US11672773B2 (en) 2020-12-13 2023-06-13 Next Science IP Holdings Pty Ltd Methods for treating ciliated cavities
US11672585B2 (en) 2021-01-12 2023-06-13 Bolt Medical, Inc. Balloon assembly for valvuloplasty catheter system
WO2022154954A1 (en) 2021-01-12 2022-07-21 Bolt Medical, Inc. Balloon assembly for valvuloplasty catheter system
US11648057B2 (en) 2021-05-10 2023-05-16 Bolt Medical, Inc. Optical analyzer assembly with safety shutdown system for intravascular lithotripsy device
US11806075B2 (en) 2021-06-07 2023-11-07 Bolt Medical, Inc. Active alignment system and method for laser optical coupling
US11839391B2 (en) 2021-12-14 2023-12-12 Bolt Medical, Inc. Optical emitter housing assembly for intravascular lithotripsy device
EP4580751A2 (en) 2022-09-29 2025-07-09 Adora Animal Health Corporation Storage stable formulations of sulfated glycosaminoglycans and fragments derived therefrom for the treatment of pain and other medical conditions

Family Cites Families (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB983130A (en) * 1962-08-06 1965-02-10 Mundipharma Ag Improvements in preparations for the removal of wax from the ear
US4002775A (en) * 1973-07-09 1977-01-11 Kabara Jon J Fatty acids and derivatives of antimicrobial agents
CA1052273A (en) * 1975-12-18 1979-04-10 Edwin B. Michaels Antimicrobial compositions
SU1128917A1 (ru) 1980-12-24 1984-12-15 Кишиневский государственный медицинский институт Способ лечени пародонтоза
US5166331A (en) 1983-10-10 1992-11-24 Fidia, S.P.A. Hyaluronics acid fractions, methods for the preparation thereof, and pharmaceutical compositions containing same
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
US5208257A (en) * 1986-04-21 1993-05-04 Kabara Jon J Topical antimicrobial pharmaceutical compositions and methods
CA1302280C (en) * 1986-04-21 1992-06-02 Jon Joseph Kabara Topical antimicrobial pharmaceutical compositions and methods
US5017229A (en) * 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US5290552A (en) * 1988-05-02 1994-03-01 Matrix Pharmaceutical, Inc./Project Hear Surgical adhesive material
IT1219587B (it) * 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US5575815A (en) 1988-08-24 1996-11-19 Endoluminal Therapeutics, Inc. Local polymeric gel therapy
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
SU1699430A1 (ru) 1989-03-03 1991-12-23 Кишиневский государственный медицинский институт Способ лечени пародонтита
EP0466397A3 (en) * 1990-07-10 1992-05-06 Kabushikikaisha Ueno Seiyaku Oyo Kenkyujo Treatment of inflammatory diseases with polyoxyethylenesorbitan mono-higher-fatty acid esters
US5662913A (en) * 1991-04-10 1997-09-02 Capelli; Christopher C. Antimicrobial compositions useful for medical applications
EP0580803B1 (en) * 1991-04-10 1999-07-07 CAPELLI, Christopher C. Antimicrobial compositions useful for medical applications
GB9204175D0 (en) * 1992-02-27 1992-04-08 Unilever Plc Cleansing composition
US5229103A (en) * 1992-04-30 1993-07-20 Hydrodent Laboratories, Inc. Antiplaque mouthwash concentrate
IT1260154B (it) * 1992-07-03 1996-03-28 Lanfranco Callegaro Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn)
CN1091315A (zh) 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
US5336163A (en) * 1993-01-06 1994-08-09 Smith & Nephew Richards, Inc. Expandable nasal stent
US5994341A (en) * 1993-07-19 1999-11-30 Angiogenesis Technologies, Inc. Anti-angiogenic Compositions and methods for the treatment of arthritis
US5480658A (en) * 1993-07-23 1996-01-02 Melman; Steven A. Ear and skin cleanser
FR2710529A1 (fr) 1993-09-29 1995-04-07 Zirinis Phedon Gel aqueux à usage nasal, pellets, et leur procédé de préparation.
US6544761B2 (en) * 1994-12-13 2003-04-08 Human Genome Sciences, Inc. Human tissue inhibitor of metalloproteinase-4
US6086921A (en) * 1995-04-25 2000-07-11 Wintrop-University Hospital Metal/thiol biocides
US5817303A (en) 1995-05-05 1998-10-06 Protein Polymer Technologies, Inc. Bonding together tissue with adhesive containing polyfunctional crosslinking agent and protein polymer
US5968542A (en) * 1995-06-07 1999-10-19 Southern Biosystems, Inc. High viscosity liquid controlled delivery system as a device
US6129761A (en) 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
CN1301139C (zh) 1995-08-29 2007-02-21 菲迪亚高级生物聚合物公司 包括透明质酸衍生物的用于预防手术后粘连的生物材料
US5601594A (en) * 1995-09-14 1997-02-11 Best; Barry D. Nasal stent
FI955389A0 (fi) 1995-11-09 1995-11-09 Antti Sakari Aaltonen Tandskyddande profylaktisk preparat och administreringsmedlen emot mellanoerpatogener
US6423694B1 (en) * 1996-02-21 2002-07-23 Inspire Pharmaceuticals, Inc. Method of treating otitis media with uridine triphosphates and related compounds
US5693065A (en) 1996-06-25 1997-12-02 Rains, Iii; B. Manrin Frontal sinus stent
JPH1072342A (ja) * 1996-06-27 1998-03-17 Senju Pharmaceut Co Ltd 界面活性剤の刺激性低下方法及び低刺激性水性組成物
US6541460B2 (en) * 1996-08-07 2003-04-01 George D. Petito Method for use of hyaluronic acid in wound management
US6063061A (en) * 1996-08-27 2000-05-16 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US6203822B1 (en) * 1996-09-03 2001-03-20 University Of Iowa Research Foundation Gallium-containing compounds for the treatment of infections caused by intracellular pathogens and pathogens causing chronic pulmonary infection
CO4910145A1 (es) 1996-10-01 2000-04-24 Smithkline Beecham Corp Uso
AU724070B2 (en) 1996-10-01 2000-09-14 Smithkline Beecham Corporation Use of mupirocin for the manufacture of a medicament for the treatment of bacterial infections associated with colonisation of the nasopharynx by pathogenic organisms
IT1287967B1 (it) * 1996-10-17 1998-09-10 Fidia Spa In Amministrazione S Preparazioni farmaceutiche per uso anestetico locale
ZA9710342B (en) * 1996-11-25 1998-06-10 Alza Corp Directional drug delivery stent and method of use.
US5709546A (en) * 1996-11-27 1998-01-20 Waggoner; Mark B. Water sanitizing system and process
FR2756739B1 (fr) * 1996-12-05 2000-04-28 Astra Ab Nouvelle formulation de budesonide
US6891037B1 (en) * 1997-01-24 2005-05-10 Schweiz. Serum- & Impfinstitut Bern Method for the isolation of polysaccharides
US6869938B1 (en) * 1997-06-17 2005-03-22 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use in reducing adhesions
US5925334A (en) * 1997-08-27 1999-07-20 Rubin; Bruce K. Use of surface active agents to promote mucus clearance
US6638621B2 (en) * 2000-08-16 2003-10-28 Lyotropic Therapeutics, Inc. Coated particles, methods of making and using
AU751182B2 (en) * 1997-12-02 2002-08-08 Archimedes Development Limited Compositions for nasal administration
US5895781A (en) * 1997-12-22 1999-04-20 S. C. Johnson & Son, Inc. Cleaning compositions for ceramic and porcelain surfaces and related methods
EP1054679B1 (en) * 1997-12-24 2003-02-12 Britannia Pharmaceuticals Limited Use of surface active agent for the manufacture of a medicament for treatment of disorders of the middle ear
US6541116B2 (en) * 1998-01-30 2003-04-01 Advanced Cardiovascular Systems, Inc. Superoxide dismutase or superoxide dismutase mimic coating for an intracorporeal medical device
IL123143A (en) * 1998-02-02 2001-08-26 Agis Ind 1983 Ltd Pharmaceutical compositions containing mupirocin
US6623521B2 (en) 1998-02-17 2003-09-23 Md3, Inc. Expandable stent with sliding and locking radial elements
US7691829B2 (en) 1998-03-24 2010-04-06 Petito George D Composition and method for healing tissues
US6824793B1 (en) 1998-06-01 2004-11-30 Chiron Corporation Use of hyaluronic acid polymers for mucosal delivery of vaccine antigens and adjuvants
US20030079758A1 (en) * 1998-06-03 2003-05-01 Siegel Phyllis B. Process and composition for removing biofilm
US20020022588A1 (en) * 1998-06-23 2002-02-21 James Wilkie Methods and compositions for sealing tissue leaks
US6706290B1 (en) * 1998-07-06 2004-03-16 Olvai E. Kajander Methods for eradication of nanobacteria
US6632457B1 (en) 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US6395746B1 (en) * 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
GB9822170D0 (en) 1998-10-13 1998-12-02 Danbioyst Uk Ltd Novel formulations of fexofenadine
WO2000027438A1 (en) * 1998-11-06 2000-05-18 Universite De Montreal Improved bactericidal and non-bactericidal solutions for removing biofilms
US8197461B1 (en) * 1998-12-04 2012-06-12 Durect Corporation Controlled release system for delivering therapeutic agents into the inner ear
US6375963B1 (en) * 1999-06-16 2002-04-23 Michael A. Repka Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof
US20020061281A1 (en) 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6576224B1 (en) 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6372229B1 (en) * 1999-09-15 2002-04-16 Cryolife, Inc. Vascular coating composition
PL201130B1 (pl) * 1999-09-24 2009-03-31 Alcon Inc Kompozycje zawiesinowe zawierające ciprofloksacynę i deksametazon do podawania miejscowego do oczu, uszu lub nosa
US6533749B1 (en) * 1999-09-24 2003-03-18 Medtronic Xomed, Inc. Angled rotary tissue cutting instrument with flexible inner member
US6156294A (en) * 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
US6676930B2 (en) * 1999-11-28 2004-01-13 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
GB0002229D0 (en) * 2000-02-01 2000-03-22 Reckitt & Colman Inc Improvements in or relating to organic compositions
DE60103023T2 (de) * 2000-02-28 2005-01-27 The Procter & Gamble Company, Cincinnati Saure antimikrobielle zusammensetzungen zur behandlung von lebensmitteln und lebensmittel-kontaktflächen und verfahren zu ihrer anwendung
US6379382B1 (en) * 2000-03-13 2002-04-30 Jun Yang Stent having cover with drug delivery capability
US20030009213A1 (en) * 2000-03-13 2003-01-09 Jun Yang Stent having cover with drug delivery capability
CA2410796C (en) 2000-06-05 2007-05-01 S.C. Johnson & Son, Inc. Biocidal cleaning method
US20020029015A1 (en) * 2000-07-04 2002-03-07 Edoardo Camenzind Device for administering a composition in a duct of a human or animal body
US6953772B2 (en) 2000-07-18 2005-10-11 Lopes John A Concentrated sanitizing compositions for cleaning food and food contact surfaces
AUPQ893200A0 (en) * 2000-07-21 2000-08-17 Whiteley, Reginald K. Medical residue treatment
US20030133883A1 (en) * 2001-06-14 2003-07-17 Finnegan Mary Beth Oral care compositions containing grapefruit seed extract
GB0100761D0 (en) * 2001-01-11 2001-02-21 Biocompatibles Ltd Drug delivery from stents
US6623513B2 (en) * 2001-01-19 2003-09-23 Advanced Photodynamic Technologies, Inc. Apparatus and method of photodynamic eradication of organisms utilizing pyrrolnitrin
DE10105592A1 (de) * 2001-02-06 2002-08-08 Achim Goepferich Platzhalter zur Arzneistofffreigabe in der Stirnhöhle
KR100492644B1 (ko) * 2001-02-26 2005-06-02 미쓰비시 지도샤 고교(주) 배기 가스 정화용 촉매
US6610314B2 (en) * 2001-03-12 2003-08-26 Kimberly-Clark Worldwide, Inc. Antimicrobial formulations
US6682695B2 (en) 2001-03-23 2004-01-27 Clearant, Inc. Methods for sterilizing biological materials by multiple rates
WO2002094854A2 (en) 2001-05-21 2002-11-28 The Brigham And Women's Hospital, Inc. P.aeruginosa mucoid exopolysaccharide specific binding peptides
WO2003023074A1 (en) * 2001-09-13 2003-03-20 Ak Properties, Inc. Method of continuously casting electrical steel strip with controlled spray cooling
DK1429780T3 (da) 2001-09-21 2006-02-13 Fremgangsmåde til behandling af mellemoreinfektioner
US20030064000A1 (en) * 2001-09-24 2003-04-03 Wilson Burgess Methods of sterilizing biological mixtures using stabilizer mixtures
WO2003061579A2 (en) 2002-01-18 2003-07-31 Emory University Phthalocyanine and porphyrazine pharmaceutical compositions
US20050042240A1 (en) * 2002-01-28 2005-02-24 Utterberg David S. High viscosity antibacterials
US20030180181A1 (en) 2002-02-01 2003-09-25 Teri Greib Methods for sterilizing tissue
RU2228203C2 (ru) 2002-04-12 2004-05-10 ООО "Наука-Сервис-Центр" Ранозаживляющий материал
EP1499341A4 (en) 2002-04-18 2010-10-27 Univ Iowa Res Found METHOD FOR INHIBITING AND TREATING BACTERIAL BIOFILMS WITH METAL CHELATE IMAGES
US6919348B2 (en) * 2002-05-02 2005-07-19 Edward T. Wei Therapeutic 1,2,3,6-tetrahydropyrimidine-2-one compositions and methods therewith
EP1374856A1 (en) 2002-06-18 2004-01-02 Impetus AG Oily thixotropic nasal spray
US7105175B2 (en) 2002-06-19 2006-09-12 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled delivery of a therapeutic agent
AU2003272517A1 (en) * 2002-09-13 2004-04-30 Zicam, Llc. Compositions to reduce congestion and methods for application thereof to the nasal membrane
US20050064508A1 (en) * 2003-09-22 2005-03-24 Semzyme Peptide mediated synthesis of metallic and magnetic materials
AU2003279067A1 (en) 2002-09-23 2004-04-08 Genta Inc. Tri(alkylcarboxylato) gallium (iii) products and pharmaceutical compositions containing them
US6770729B2 (en) * 2002-09-30 2004-08-03 Medtronic Minimed, Inc. Polymer compositions containing bioactive agents and methods for their use
BR0314952A (pt) * 2002-09-30 2005-08-02 Bausch & Lomb Método para inibir a aderência de bactérias a uma superfìcie de um dispositivo biomédico
EP1567101A4 (en) 2002-10-22 2009-06-03 Nucryst Pharm Corp PROPHYLACTIC TREATMENT METHODS
US20040101506A1 (en) * 2002-11-25 2004-05-27 Fust Charles A. Composition for the prevention and treatment of inflammation of the ear
US7220431B2 (en) * 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
US7491234B2 (en) * 2002-12-03 2009-02-17 Boston Scientific Scimed, Inc. Medical devices for delivery of therapeutic agents
GB2397067B (en) * 2002-12-23 2005-05-11 Destiny Pharma Ltd Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation
CA2518960C (en) * 2003-03-14 2013-08-27 Sinexus, Inc. Sinus delivery of sustained release therapeutics
US20040214753A1 (en) 2003-03-20 2004-10-28 Britten Nancy Jean Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
US20040213758A1 (en) 2003-04-23 2004-10-28 Rimon Therapeutics Ltd. Hydroxyamate-containing materials for the inhibition of matrix metalloproteinases
US7090882B2 (en) 2003-06-12 2006-08-15 Cargill, Incorporated Antimicrobial salt solutions for food safety applications
US20050003007A1 (en) * 2003-07-02 2005-01-06 Michele Boix Method of sterilization of polymeric microparticles
US7341983B2 (en) 2003-08-04 2008-03-11 Ecolab Inc. Antimicrobial compositions including carboxylic acids and alkoxylated amines
CA2535846A1 (en) * 2003-08-15 2005-02-24 Qlt Usa, Inc. Adhesive bioerodible transmucosal drug delivery system
US20050080396A1 (en) 2003-10-03 2005-04-14 Michael Rontal Method and apparatus for the ultrasonic cleaning of biofilm coated surfaces
DE10347994A1 (de) 2003-10-15 2005-06-16 Pari GmbH Spezialisten für effektive Inhalation Wässrige Aerosol-Zubereitung
CN1901801B (zh) * 2003-12-04 2013-01-16 衣阿华大学研究基金会 镓抑制生物膜形成
ZA200605583B (en) 2003-12-17 2009-06-24 Titan Pharmaceuticals Inc Use of gallium to treat inflammatory arthritis
EP2286791B1 (en) * 2003-12-30 2014-03-26 Durect Corporation Polymeric implants, preferably containing a mixture of PEG and PLG, for controlled release of active agents
US7541320B2 (en) * 2004-01-23 2009-06-02 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Mild, viscous cleansing composition with versatile compatibility and enhanced conditioning
US20100016267A1 (en) 2004-03-15 2010-01-21 Felix Theeuwes Pharmaceutical compositions for administraton to a sinus
EP1737378A2 (en) * 2004-04-02 2007-01-03 Baylor College of Medicine Novel modification of medical prostheses
US7803150B2 (en) * 2004-04-21 2010-09-28 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US7410480B2 (en) * 2004-04-21 2008-08-12 Acclarent, Inc. Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders
US20050282722A1 (en) 2004-06-16 2005-12-22 Mcreynolds Kent B Two part cleaning composition
US7494963B2 (en) * 2004-08-11 2009-02-24 Delaval Holding Ab Non-chlorinated concentrated all-in-one acid detergent and method for using the same
US20060045850A1 (en) * 2004-08-30 2006-03-02 Qpharma, Llc Nasal delivery of cyclodextrin complexes of anti-inflammatory steroids
US9028852B2 (en) * 2004-09-07 2015-05-12 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
US20080248558A1 (en) 2004-09-10 2008-10-09 Novozymes A/S Methods For Preventing, Removing, Reducing, or Disrupting Biofilm
US20060079420A1 (en) * 2004-10-08 2006-04-13 Wagner Julie A Multi-phase personal cleansing composition
CN101137359B (zh) * 2005-03-10 2011-01-12 3M创新有限公司 治疗耳感染的方法
WO2006099386A2 (en) 2005-03-11 2006-09-21 Massachusetts Institute Of Technology Synthesis and use of colloidal iii-v nanoparticles
US7959943B2 (en) 2006-05-10 2011-06-14 Medtronics Xomed, Inc. Solvating system and sealant for medical use in the middle or inner ear
US7976873B2 (en) 2006-05-10 2011-07-12 Medtronic Xomed, Inc. Extracellular polysaccharide solvating system for treatment of bacterial ear conditions
US7993675B2 (en) 2006-05-10 2011-08-09 Medtronic Xomed, Inc. Solvating system and sealant for medical use in the sinuses and nasal passages
US7998404B2 (en) * 2006-07-13 2011-08-16 Advanced Cardiovascular Systems, Inc. Reduced temperature sterilization of stents
WO2008097317A1 (en) 2007-02-08 2008-08-14 Medtronic Xomed, Inc. Solvating system and sealant for medical use

Also Published As

Publication number Publication date
EP2029232A1 (en) 2009-03-04
JP2014240419A (ja) 2014-12-25
CA2651646A1 (en) 2007-11-22
AU2007249413A1 (en) 2007-11-22
EP2029232B1 (en) 2017-09-20
US20070264353A1 (en) 2007-11-15
CA2651646C (en) 2015-01-27
ES2650974T3 (es) 2018-01-23
KR20090005162A (ko) 2009-01-12
US7976873B2 (en) 2011-07-12
KR101453011B1 (ko) 2014-10-21
JP2009536666A (ja) 2009-10-15
CN104815328A (zh) 2015-08-05
WO2007134055A1 (en) 2007-11-22
AU2007249413B2 (en) 2012-08-30

Similar Documents

Publication Publication Date Title
JP5912218B2 (ja) 抗細菌性細胞外多糖溶媒和系
CN101626762B (zh) 用于医药用途的溶剂化体系及密封剂
US7959943B2 (en) Solvating system and sealant for medical use in the middle or inner ear
US7993675B2 (en) Solvating system and sealant for medical use in the sinuses and nasal passages
CN101443079A (zh) 抗菌的细胞外多糖溶剂化体系
KR101421765B1 (ko) 의료용 용매화 시스템 및 실런트
Shikani et al. Topical therapy for refractory rhinosinusitis caused by methicillin-resistant Staphylococcus aureus: First report in a prospective series
US9848604B2 (en) Antimicrobial wash
AU2013211488B2 (en) Solvating system and sealant for medical use
RU2418574C2 (ru) Сольватирующая система и герметик для медицинского применения
HK1130717A (en) Antibacterial extracellular polysaccharide solvating system
Zabolotna et al. Bacterial Biofilms in Chronic Rhinosinusitis. Clinical Role and Current Therapeutic Strategies

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100507

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20100507

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20121002

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20121227

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130109

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130131

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130801

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20131101

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20131111

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20131128

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20131205

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140203

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20140203

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20140428

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140828

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20141017

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20141128

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20150310

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20151222

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20160401

R150 Certificate of patent or registration of utility model

Ref document number: 5912218

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees