JP5911514B2 - 脂質低下抗糖尿病薬 - Google Patents
脂質低下抗糖尿病薬 Download PDFInfo
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- JP5911514B2 JP5911514B2 JP2013549539A JP2013549539A JP5911514B2 JP 5911514 B2 JP5911514 B2 JP 5911514B2 JP 2013549539 A JP2013549539 A JP 2013549539A JP 2013549539 A JP2013549539 A JP 2013549539A JP 5911514 B2 JP5911514 B2 JP 5911514B2
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Classifications
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
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- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/52—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing groups, e.g. carboxylic acid amidines
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/04—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C251/06—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton
- C07C251/08—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton being acyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/03—Monocarboxylic acids
Landscapes
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- Cardiology (AREA)
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- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pest Control & Pesticides (AREA)
- Urology & Nephrology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161461113P | 2011-01-12 | 2011-01-12 | |
| US61/461,113 | 2011-01-12 | ||
| US13/348,265 US20120178813A1 (en) | 2011-01-12 | 2012-01-11 | Lipid-lowering antidiabetic agent |
| US13/348,265 | 2012-01-11 | ||
| PCT/US2012/021070 WO2012097144A1 (en) | 2011-01-12 | 2012-01-12 | Lipid-lowering antidiabetic agent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014512333A JP2014512333A (ja) | 2014-05-22 |
| JP2014512333A5 JP2014512333A5 (https=) | 2015-03-12 |
| JP5911514B2 true JP5911514B2 (ja) | 2016-04-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2013549539A Expired - Fee Related JP5911514B2 (ja) | 2011-01-12 | 2012-01-12 | 脂質低下抗糖尿病薬 |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US20120178813A1 (https=) |
| EP (1) | EP2663186A4 (https=) |
| JP (1) | JP5911514B2 (https=) |
| KR (1) | KR20140092228A (https=) |
| CN (1) | CN103533833B (https=) |
| AU (1) | AU2012205547B2 (https=) |
| BR (1) | BR112013017845A2 (https=) |
| CA (1) | CA2824192A1 (https=) |
| EA (1) | EA201391028A1 (https=) |
| IL (1) | IL227346A0 (https=) |
| MX (1) | MX2013008131A (https=) |
| WO (1) | WO2012097144A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120178813A1 (en) | 2011-01-12 | 2012-07-12 | Thetis Pharmaceuticals Llc | Lipid-lowering antidiabetic agent |
| CN104684889A (zh) * | 2012-07-10 | 2015-06-03 | 西蒂斯制药有限责任公司 | 二甲双胍的三盐形式 |
| US8765811B2 (en) | 2012-07-10 | 2014-07-01 | Thetis Pharmaceuticals Llc | Tri-salt form of metformin |
| US9382187B2 (en) | 2012-07-10 | 2016-07-05 | Thetis Pharmaceuticals Llc | Tri-salt form of metformin |
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| CN103533833A (zh) | 2014-01-22 |
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| US8901107B2 (en) | 2014-12-02 |
| WO2012097144A1 (en) | 2012-07-19 |
| US9012507B2 (en) | 2015-04-21 |
| KR20140092228A (ko) | 2014-07-23 |
| EA201391028A1 (ru) | 2013-12-30 |
| EP2663186A1 (en) | 2013-11-20 |
| US20140107360A1 (en) | 2014-04-17 |
| CA2824192A1 (en) | 2012-07-19 |
| EP2663186A4 (en) | 2014-09-24 |
| IL227346A0 (en) | 2013-09-30 |
| JP2014512333A (ja) | 2014-05-22 |
| AU2012205547A1 (en) | 2013-08-01 |
| US20120178813A1 (en) | 2012-07-12 |
| CN103533833B (zh) | 2016-08-31 |
| US20150051284A1 (en) | 2015-02-19 |
| AU2012205547B2 (en) | 2015-08-27 |
| US9216951B2 (en) | 2015-12-22 |
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