JP5888753B2 - 効率的な人工多能性幹細胞の樹立方法 - Google Patents
効率的な人工多能性幹細胞の樹立方法 Download PDFInfo
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- JP5888753B2 JP5888753B2 JP2013512280A JP2013512280A JP5888753B2 JP 5888753 B2 JP5888753 B2 JP 5888753B2 JP 2013512280 A JP2013512280 A JP 2013512280A JP 2013512280 A JP2013512280 A JP 2013512280A JP 5888753 B2 JP5888753 B2 JP 5888753B2
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/604—Klf-4
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/605—Nanog
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Developmental Biology & Embryology (AREA)
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- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41017810P | 2010-11-04 | 2010-11-04 | |
| US61/410,178 | 2010-11-04 | ||
| PCT/JP2011/076017 WO2012060473A1 (en) | 2010-11-04 | 2011-11-04 | Method of efficiently establishing induced pluripotent stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013544069A JP2013544069A (ja) | 2013-12-12 |
| JP2013544069A5 JP2013544069A5 (enExample) | 2014-12-18 |
| JP5888753B2 true JP5888753B2 (ja) | 2016-03-22 |
Family
ID=46024582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013512280A Active JP5888753B2 (ja) | 2010-11-04 | 2011-11-04 | 効率的な人工多能性幹細胞の樹立方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9637732B2 (enExample) |
| EP (1) | EP2635678A4 (enExample) |
| JP (1) | JP5888753B2 (enExample) |
| WO (1) | WO2012060473A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX382822B (es) | 2011-12-05 | 2025-03-13 | Factor Bioscience Inc | Metodos y productos para transfeccion de celulas. |
| US8497124B2 (en) | 2011-12-05 | 2013-07-30 | Factor Bioscience Inc. | Methods and products for reprogramming cells to a less differentiated state |
| BR122019025678B1 (pt) | 2012-11-01 | 2023-04-18 | Factor Bioscience Inc | Composições que compreendem ácido nucleico que codifica uma proteína de edição gênica |
| ES2787198T3 (es) | 2014-01-31 | 2020-10-15 | Factor Bioscience Inc | ARN sintético para su uso en el tratamiento de la epidermólisis ampollosa distrófica |
| CA2976376A1 (en) | 2015-02-13 | 2016-08-18 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| CN116376812A (zh) | 2016-05-25 | 2023-07-04 | 国家医疗保健研究所 | 治疗癌症的方法和组合物 |
| JP2019528284A (ja) | 2016-08-17 | 2019-10-10 | ファクター バイオサイエンス インコーポレイテッド | 核酸産物およびその投与方法 |
| EP3713596A1 (en) | 2017-11-24 | 2020-09-30 | Institut National de la Santé Et de la Recherche Médicale | Methods and compositions for treating cancers |
| US20210236633A1 (en) | 2018-08-06 | 2021-08-05 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and compositions for treating cancers |
| CN114207118A (zh) | 2019-05-14 | 2022-03-18 | 阿利夫农场公司 | 多能细胞聚集体及其用途 |
| CN114450265B (zh) | 2019-07-03 | 2024-12-24 | 菲克特生物科学股份有限公司 | 阳离子脂质及其用途 |
| US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
| EP4251735A4 (en) | 2020-11-24 | 2025-02-26 | Monash University | METHODS AND CELLULAR STRUCTURES |
| EP4251739A4 (en) | 2020-11-24 | 2025-02-26 | Monash University | INDUCED STEM CELLS |
| US20240279612A1 (en) | 2021-04-01 | 2024-08-22 | Institut National de la Santé et de la Recherche Médicale | Liver organoid manufacturing methods, liver organoids obtained with the same, and uses thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ307399A0 (en) | 1999-09-24 | 1999-10-21 | Luminis Pty Limited | Cell cycle control |
| US9567591B2 (en) * | 2003-05-15 | 2017-02-14 | Mello Biotechnology, Inc. | Generation of human embryonic stem-like cells using intronic RNA |
| NZ569530A (en) * | 2005-12-13 | 2011-07-29 | Univ Kyoto | Nuclear reprogramming factor |
| AU2008236629B2 (en) | 2007-04-07 | 2014-03-06 | Whitehead Institute For Biomedical Research | Reprogramming of somatic cells |
| AU2008297024B2 (en) * | 2007-10-31 | 2014-08-28 | Kyoto University | Nuclear reprogramming method |
| CN101970664B (zh) | 2008-01-16 | 2013-08-21 | 林希龙 | 使用可诱导的重组核糖核酸因子生成不含肿瘤的类胚胎干细胞的多能性细胞 |
| JP2011525794A (ja) * | 2008-06-26 | 2011-09-29 | 国立大学法人大阪大学 | iPS細胞の製造方法および製造キット |
| US8530238B2 (en) * | 2008-06-27 | 2013-09-10 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| EP2295538B1 (en) * | 2008-07-07 | 2015-10-21 | Takara Bio Inc. | Method for production of pluripotent stem cell |
-
2011
- 2011-11-04 WO PCT/JP2011/076017 patent/WO2012060473A1/en not_active Ceased
- 2011-11-04 EP EP11838120.1A patent/EP2635678A4/en not_active Withdrawn
- 2011-11-04 US US13/824,087 patent/US9637732B2/en active Active
- 2011-11-04 JP JP2013512280A patent/JP5888753B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20130183757A1 (en) | 2013-07-18 |
| EP2635678A4 (en) | 2014-04-23 |
| US9637732B2 (en) | 2017-05-02 |
| WO2012060473A1 (en) | 2012-05-10 |
| JP2013544069A (ja) | 2013-12-12 |
| EP2635678A1 (en) | 2013-09-11 |
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