JP5883458B2 - ポリ硫酸化多糖類を用いる骨髄浮腫（ｅｄｅｍａ（ｏｅｄｅｍａ））の治療 - Google Patents

ポリ硫酸化多糖類を用いる骨髄浮腫（ｅｄｅｍａ（ｏｅｄｅｍａ））の治療 Download PDF

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JP5883458B2
JP5883458B2 JP2013552065A JP2013552065A JP5883458B2 JP 5883458 B2 JP5883458 B2 JP 5883458B2 JP 2013552065 A JP2013552065 A JP 2013552065A JP 2013552065 A JP2013552065 A JP 2013552065A JP 5883458 B2 JP5883458 B2 JP 5883458B2
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pentosan polysulfate
polysulfate
molecular weight
composition
weight heparin
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JP2014504613A5 (https=
JP2014504613A (ja
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ゴーシュ，ピーター
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パラダイム ヘルス サイエンシズ プロプライエタリー リミテッド
パラダイム ヘルス サイエンシズ プロプライエタリー リミテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2013552065A 2011-02-02 2012-02-02 ポリ硫酸化多糖類を用いる骨髄浮腫（ｅｄｅｍａ（ｏｅｄｅｍａ））の治療 Active JP5883458B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2011900325 2011-02-02
AU2011900325A AU2011900325A0 (en) 2011-02-02 Treatment of bone marrow edema (oedema) with polysulfated polysaccharides
PCT/AU2012/000091 WO2012103588A1 (en) 2011-02-02 2012-02-02 Treatment of bone marrow edema (oedema) with polysulfated polysaccharides

Publications (3)

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JP2014504613A JP2014504613A (ja) 2014-02-24
JP2014504613A5 JP2014504613A5 (https=) 2015-03-19
JP5883458B2 true JP5883458B2 (ja) 2016-03-15

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JP2013552065A Active JP5883458B2 (ja) 2011-02-02 2012-02-02 ポリ硫酸化多糖類を用いる骨髄浮腫（ｅｄｅｍａ（ｏｅｄｅｍａ））の治療

Country Status (15)

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US (6) US9101650B2 (https=)
EP (1) EP2670412B1 (https=)
JP (1) JP5883458B2 (https=)
KR (1) KR101840079B1 (https=)
CN (1) CN103415293B (https=)
AU (1) AU2012212398B2 (https=)
CA (1) CA2826166C (https=)
DK (1) DK2670412T3 (https=)
ES (1) ES2664611T3 (https=)
MY (1) MY164728A (https=)
NO (1) NO2670412T3 (https=)
PT (1) PT2670412T (https=)
SG (1) SG192238A1 (https=)
TW (1) TWI520740B (https=)
WO (1) WO2012103588A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2926888C (en) * 2013-10-22 2020-03-24 Cell Receptor Sa Modulation of the physical interaction between platelets and the cell surface effecting cell proliferation
WO2019023761A1 (en) * 2017-08-04 2019-02-07 Paradigm Biopharmaceuticals Ltd TREATMENT OF MEDICAL PATHOLOGIES WITH POLYSULFATED POLYSACCHARIDES
EP3813849A4 (en) 2018-02-16 2021-12-08 Proteobioactives Pty Limited METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN AND / OR INFLAMMATION
US11701382B2 (en) 2018-02-28 2023-07-18 Paradigm Biopharmaceuticals Ltd Treatment of post-operative joint pain with polysulfated polysaccharides
EP3863647B1 (en) * 2018-10-10 2024-02-14 Paradigm Biopharmaceuticals Limited Treatment of malignant bone pain with pentosan polysulfate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5668116A (en) 1987-03-19 1997-09-16 Anthropharm Pty. Limited Anti-inflammatory compounds and compositions
US6593310B1 (en) 2000-11-21 2003-07-15 Arthropharm Pty. Ltd. Treatment of osteoporosis
US6564083B2 (en) * 2000-12-18 2003-05-13 Hoffmann-La Roche Inc. Bone marrow edema as predictive of susceptibility to developing progressive osteoarthritis
DE10225551A1 (de) * 2002-06-06 2003-12-24 Schering Ag Verwendung von oral verfügbaren Prostacyclinderivaten für die Herstellung eines Arzneimittels zur Behandlung von Krankheiten, die mit Knochenmarködemen assoziiert sind
JP5542686B2 (ja) * 2007-12-04 2014-07-09 プロテオバイオアクティブズ・ピーティーワイ・リミテッド 前駆細胞の保護およびその分化の調節

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Publication number Publication date
EP2670412A4 (en) 2015-07-08
TWI520740B (zh) 2016-02-11
CA2826166A1 (en) 2012-08-09
MY164728A (en) 2018-01-30
DK2670412T3 (en) 2018-03-12
US20180021369A1 (en) 2018-01-25
US20220362284A1 (en) 2022-11-17
AU2012212398A1 (en) 2013-09-19
SG192238A1 (en) 2013-09-30
JP2014504613A (ja) 2014-02-24
EP2670412B1 (en) 2018-01-03
ES2664611T3 (es) 2018-04-20
CA2826166C (en) 2017-05-09
CN103415293B (zh) 2016-08-10
US10610542B2 (en) 2020-04-07
US20140024614A1 (en) 2014-01-23
TW201309307A (zh) 2013-03-01
NO2670412T3 (https=) 2018-06-02
US9861657B2 (en) 2018-01-09
KR101840079B1 (ko) 2018-03-19
US20210015849A1 (en) 2021-01-21
WO2012103588A1 (en) 2012-08-09
US9101650B2 (en) 2015-08-11
EP2670412A1 (en) 2013-12-11
US20150297633A1 (en) 2015-10-22
US20240156858A1 (en) 2024-05-16
US11406660B2 (en) 2022-08-09
AU2012212398B2 (en) 2014-06-05
CN103415293A (zh) 2013-11-27
KR20140012655A (ko) 2014-02-03
PT2670412T (pt) 2018-03-20

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