JP5873332B2 - 新規化合物および方法 - Google Patents

新規化合物および方法 Download PDF

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Publication number
JP5873332B2
JP5873332B2 JP2011519185A JP2011519185A JP5873332B2 JP 5873332 B2 JP5873332 B2 JP 5873332B2 JP 2011519185 A JP2011519185 A JP 2011519185A JP 2011519185 A JP2011519185 A JP 2011519185A JP 5873332 B2 JP5873332 B2 JP 5873332B2
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JP
Japan
Prior art keywords
seq
polypeptide
sequence
rv3616c
tuberculosis
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Expired - Fee Related
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JP2011519185A
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English (en)
Japanese (ja)
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JP2011528895A (ja
JP2011528895A5 (cg-RX-API-DMAC7.html
Inventor
ブラウン，ジェームズ
メッテンス，パスカル
マーフィー，デニス
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Glaxo Group Ltd
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Glaxo Group Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
JP2011519185A 2008-07-25 2009-07-24 新規化合物および方法 Expired - Fee Related JP5873332B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8372008P 2008-07-25 2008-07-25
US61/083,720 2008-07-25
PCT/EP2009/059580 WO2010010177A1 (en) 2008-07-25 2009-07-24 Novel compositions and methods

Publications (3)

Publication Number Publication Date
JP2011528895A JP2011528895A (ja) 2011-12-01
JP2011528895A5 JP2011528895A5 (cg-RX-API-DMAC7.html) 2012-09-06
JP5873332B2 true JP5873332B2 (ja) 2016-03-01

Family

ID=41217660

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011519185A Expired - Fee Related JP5873332B2 (ja) 2008-07-25 2009-07-24 新規化合物および方法

Country Status (24)

Country Link
US (2) US20110117119A1 (cg-RX-API-DMAC7.html)
EP (1) EP2315773B1 (cg-RX-API-DMAC7.html)
JP (1) JP5873332B2 (cg-RX-API-DMAC7.html)
KR (1) KR20110044883A (cg-RX-API-DMAC7.html)
CN (1) CN102164952B (cg-RX-API-DMAC7.html)
AU (1) AU2009273130B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0916703A2 (cg-RX-API-DMAC7.html)
CA (1) CA2731499C (cg-RX-API-DMAC7.html)
CO (1) CO6341637A2 (cg-RX-API-DMAC7.html)
CY (1) CY1118200T1 (cg-RX-API-DMAC7.html)
DK (1) DK2315773T3 (cg-RX-API-DMAC7.html)
EA (1) EA024826B1 (cg-RX-API-DMAC7.html)
ES (1) ES2602430T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20161458T1 (cg-RX-API-DMAC7.html)
HU (1) HUE031044T2 (cg-RX-API-DMAC7.html)
IL (1) IL210559A0 (cg-RX-API-DMAC7.html)
LT (1) LT2315773T (cg-RX-API-DMAC7.html)
MX (1) MX2011000983A (cg-RX-API-DMAC7.html)
PL (1) PL2315773T3 (cg-RX-API-DMAC7.html)
PT (1) PT2315773T (cg-RX-API-DMAC7.html)
SG (1) SG192456A1 (cg-RX-API-DMAC7.html)
SI (1) SI2315773T1 (cg-RX-API-DMAC7.html)
UA (1) UA107330C2 (cg-RX-API-DMAC7.html)
WO (1) WO2010010177A1 (cg-RX-API-DMAC7.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000026248A2 (en) * 1998-11-04 2000-05-11 Isis Innovation Limited Tuberculosis diagnostic test
LT2315834T (lt) 2008-07-25 2018-09-10 Glaxosmithkline Biologicals S.A. Tuberkuliozės rv2386c baltymas, kompozicijos ir jų panaudojimas
ES2647321T3 (es) 2008-07-25 2017-12-20 Glaxosmithkline Biologicals S.A. Composiciones y procedimientos novedosos
EP2156945A1 (en) 2008-08-13 2010-02-24 Novelis Inc. Clad automotive sheet product
EP2421557B1 (en) 2009-04-24 2018-12-05 Statens Serum Institut A tuberculosis tb vaccine to prevent reactivation
HRP20161608T1 (hr) * 2010-01-27 2017-01-13 Glaxosmithkline Biologicals Sa Modificirani tuberkulozni antigeni
JP6857029B2 (ja) 2013-09-27 2021-04-14 コデクシス， インコーポレイテッド 酵素バリアントの自動スクリーニング
HUE048104T2 (hu) * 2013-09-27 2020-05-28 Codexis Inc Szerkezet alapú prediktív modellezés
GB201405921D0 (en) * 2014-04-02 2014-05-14 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response
CN106546737A (zh) * 2016-10-24 2017-03-29 广州迪澳医疗科技有限公司 一种体外检测活动性结核的方法
GB201621686D0 (en) 2016-12-20 2017-02-01 Glaxosmithkline Biologicals Sa Novel methods for inducing an immune response
GB201707700D0 (en) 2017-05-12 2017-06-28 Glaxosmithkline Biologicals Sa Dried composition
GB2600654B (en) 2017-05-30 2022-11-02 Glaxosmithkline Biologicals Sa Novel devices
MX2020005481A (es) 2017-12-01 2020-12-07 Glaxosmithkline Biologicals Sa Purificacion de saponina.
CA3252762A1 (en) 2019-04-12 2025-07-08 C4 Therapeutics, Inc. Tricyclic degraders of ikaros and aiolos
US20220235095A1 (en) 2019-06-05 2022-07-28 Glaxosmithkline Biologicals Sa Saponin purification
CN115073612B (zh) * 2022-06-22 2024-09-27 宁夏大学 一种结核分枝杆菌Zera-71cA蛋白纳米颗粒、制备方法及其用途
GB202318595D0 (en) * 2023-12-05 2024-01-17 Sec Dep For Environment Food And Rural Affairs Acting Through Animal And Plant Health Agency Diagnostic proteins and reagents

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7087713B2 (en) * 2000-02-25 2006-08-08 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
US6613881B1 (en) * 1997-05-20 2003-09-02 Corixa Corporation Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
CN1163602C (zh) * 1998-04-07 2004-08-25 科里克萨公司 结核杆菌抗原融合蛋白及其应用
DK2133100T3 (da) * 2000-06-20 2012-01-23 Corixa Corp MTB32A-Antigen af Mycobacterium tuberculosis med inaktiveret aktivt sted og fusionsproteiner deraf
CZ20031866A3 (cs) * 2001-01-08 2004-03-17 Isis Innovation Limited Způsob pro stanovení účinnosti léčení mykobakteriální infekce
CN1277843C (zh) * 2001-02-22 2006-10-04 巴斯德研究院 分枝杆菌比较基因组学作为鉴定分枝杆菌病的诊断、预防或治疗靶的工具
US20030236393A1 (en) * 2002-03-22 2003-12-25 United States Of America Dept Of Vetrans Affairs Virulence genes of M. marinum and M. tuberculosis
EP1781313A4 (en) * 2004-06-17 2009-08-26 Beckman Coulter Inc MYCOBACTERIUM TUBERCULOSIS EPITOPES AND METHODS OF USE
EP2457926B1 (en) 2005-04-29 2014-09-24 GlaxoSmithKline Biologicals S.A. Novel method for preventing or treating M. tuberculosis infection
EP2380589A3 (en) * 2005-06-23 2012-09-12 Statens Serum Institut Improved tuberculosis vaccines
WO2008007942A1 (en) * 2006-07-10 2008-01-17 Het Nederlands Kanker Instituut Means and methods for manipulating sequential phagolysomal-cytosolic translocation of mycobacteria, and uses thereof
CA2668100C (en) * 2006-11-01 2014-12-23 Immport Therapeutics, Inc. Compositions and methods for immunodominant antigens
EP2421557B1 (en) * 2009-04-24 2018-12-05 Statens Serum Institut A tuberculosis tb vaccine to prevent reactivation
HRP20161608T1 (hr) 2010-01-27 2017-01-13 Glaxosmithkline Biologicals Sa Modificirani tuberkulozni antigeni

Also Published As

Publication number Publication date
IL210559A0 (en) 2011-03-31
AU2009273130B2 (en) 2014-10-16
HUE031044T2 (en) 2017-06-28
CN102164952A (zh) 2011-08-24
PL2315773T3 (pl) 2017-07-31
ES2602430T3 (es) 2017-02-21
CO6341637A2 (es) 2011-11-21
AU2009273130A1 (en) 2010-01-28
UA107330C2 (uk) 2014-12-25
SG192456A1 (en) 2013-08-30
EP2315773B1 (en) 2016-08-24
EA201100072A1 (ru) 2011-10-31
DK2315773T3 (en) 2016-12-12
CA2731499A1 (en) 2010-01-28
HRP20161458T1 (hr) 2016-12-16
CY1118200T1 (el) 2017-06-28
JP2011528895A (ja) 2011-12-01
US20110117119A1 (en) 2011-05-19
CN102164952B (zh) 2016-05-25
EA024826B1 (ru) 2016-10-31
LT2315773T (lt) 2016-11-10
KR20110044883A (ko) 2011-05-02
BRPI0916703A2 (pt) 2019-12-24
PT2315773T (pt) 2016-11-23
MX2011000983A (es) 2011-03-02
EP2315773A1 (en) 2011-05-04
SI2315773T1 (sl) 2016-12-30
US20140178423A1 (en) 2014-06-26
WO2010010177A1 (en) 2010-01-28
US9795663B2 (en) 2017-10-24
CA2731499C (en) 2017-01-10

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