JP5823969B2 - 心臓特異的核酸調節因子ならびにこの方法および使用 - Google Patents
心臓特異的核酸調節因子ならびにこの方法および使用 Download PDFInfo
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| EP09174519.0 | 2009-10-29 | ||
| EP09174519 | 2009-10-29 | ||
| PCT/EP2010/066474 WO2011051450A1 (en) | 2009-10-29 | 2010-10-29 | Cardiac-specific nucleic acid regulatory elements and methods and use thereof |
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| JP2013509168A JP2013509168A (ja) | 2013-03-14 |
| JP2013509168A5 JP2013509168A5 (enExample) | 2013-12-19 |
| JP5823969B2 true JP5823969B2 (ja) | 2015-11-25 |
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| EP (1) | EP2494058B1 (enExample) |
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| CA2778945A1 (en) | 2009-10-29 | 2011-05-05 | Vib Vzw | Cardiac-specific nucleic acid regulatory elements and methods and use thereof |
| US8859517B2 (en) * | 2011-08-08 | 2014-10-14 | Fondazione Salvatore Maugeri Clinica Del Lavoro E Della Riabilitazione | Method of gene transfer for the treatment of recessive catecholaminergic polymorphic ventricular tachycardia (CPVT) |
| US20130136729A1 (en) * | 2011-11-11 | 2013-05-30 | University of Virginia Patent Foundation, d/b/a University of Virginia Licensing & Ventures Group | Compositions and methods for targeting and treating diseases and injuries using adeno-associated virus vectors |
| WO2014077863A1 (en) * | 2012-11-19 | 2014-05-22 | Nature Technology Corporation | Replicative minicircle vectors with improved expression |
| EP3572513B1 (en) | 2013-12-09 | 2025-09-24 | Baylor College of Medicine | Hippo and dystrophin complex signaling in cardiomyocyte renewal |
| PL3097197T3 (pl) * | 2014-01-21 | 2021-06-28 | Vrije Universiteit Brussel | Mięśniowo-specyficzne elementy regulatorowe kwasów nukleinowych oraz sposoby i ich zastosowanie |
| US10570183B2 (en) * | 2016-04-19 | 2020-02-25 | The Board Of Regents Of The University Of Texas System | Use of a small native peptide activator of SERCA pump for treatment of heart failure and other disorders characterized by cytosolic calcium overload |
| AU2018241847A1 (en) | 2017-03-27 | 2019-10-17 | Vrije Universiteit Brussel | Diaphragm-specific nucleic acid regulatory elements and methods and use thereof |
| CN113166767B (zh) * | 2018-09-05 | 2025-03-28 | 马克思-德布鲁克-分子医学中心亥姆霍兹联合会 | 用于工程合成顺式调控dna的方法 |
| WO2020084162A1 (en) | 2018-10-26 | 2020-04-30 | Vrije Universiteit Brussel | Liver-specific nucleic acid regulatory elements and methods and use thereof |
| US20230047424A1 (en) * | 2019-12-09 | 2023-02-16 | Ucl Business Ltd | Gene therapy composition and treatment for myh7-linked cardiomyopathy |
| IL294238A (en) * | 2019-12-24 | 2022-08-01 | Asklepios Biopharmaceutical Inc | Nucleic acid regulatory sequences |
| WO2021165350A1 (en) | 2020-02-18 | 2021-08-26 | Vrije Universiteit Brussel | Novel combination of nucleic acid regulatory elements and methods and uses thereof |
| US20240050591A1 (en) | 2020-12-21 | 2024-02-15 | Vrije Universiteit Brussel | Cardiomyocyte-derived nucleic acid regulatory elements and methods and use thereof |
| AR126407A1 (es) | 2021-07-08 | 2023-10-11 | Tenaya Therapeutics Inc | Casetes de expresión optimizada para genoterapia |
| AR126660A1 (es) | 2021-07-28 | 2023-11-01 | Univ Brussel Vrije | Mejorando la eficacia de la terapia génica dirigida a músculos |
Family Cites Families (11)
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| FR2797273B1 (fr) * | 1999-08-06 | 2004-01-02 | Pasteur Institut | Polynucleotides dirigeant l'activation de l'expression d'un gene dans le coeur et ses applications a la therapie genique |
| CA2396348A1 (en) * | 2000-01-14 | 2001-07-19 | Beth Israel Deaconess Medical Center | Cardiac-cell specific enhancer elements and uses thereof |
| ATE373095T1 (de) * | 2000-07-14 | 2007-09-15 | Univ Michigan | Mutierte muskelspezifische enhancer |
| US20050004058A1 (en) * | 2000-12-07 | 2005-01-06 | Patrick Benoit | Sequences upstream of the carp gene, vectors containing them and uses thereof |
| US7714100B2 (en) * | 2004-01-27 | 2010-05-11 | Compugen Ltd | Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of cardiac disease |
| EP1781776A2 (en) * | 2004-07-29 | 2007-05-09 | Stem Cell Innovations, Inc. | Differentiation of stem cells |
| US20080081354A1 (en) * | 2006-10-02 | 2008-04-03 | Cardiac Pacemakers, Inc. | Devices, vectors and methods for inducible ischemia cardioprotection |
| WO2008054713A2 (en) * | 2006-10-30 | 2008-05-08 | Thomas Jefferson University | Tissue specific gene therapy treatment |
| US20110027234A1 (en) * | 2007-04-11 | 2011-02-03 | Technion Research & Development Foundation Ltd. | Methods for identification and selection of human embryonic stem cell derived cells |
| WO2009130208A1 (en) | 2008-04-22 | 2009-10-29 | Vib Vzw | Liver-specific nucleic acid regulatory elements and methods and use thereof |
| CA2778945A1 (en) | 2009-10-29 | 2011-05-05 | Vib Vzw | Cardiac-specific nucleic acid regulatory elements and methods and use thereof |
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- 2010-10-29 WO PCT/EP2010/066474 patent/WO2011051450A1/en not_active Ceased
- 2010-10-29 AU AU2010311376A patent/AU2010311376B2/en not_active Ceased
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| JP2013509168A (ja) | 2013-03-14 |
| CA2778945A1 (en) | 2011-05-05 |
| US20120252882A1 (en) | 2012-10-04 |
| WO2011051450A1 (en) | 2011-05-05 |
| AU2010311376B2 (en) | 2014-07-03 |
| EP2494058B1 (en) | 2017-04-05 |
| AU2010311376A1 (en) | 2012-05-24 |
| EP2494058A1 (en) | 2012-09-05 |
| AU2010311376A2 (en) | 2012-07-12 |
| US9353164B2 (en) | 2016-05-31 |
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