JP5805190B2 - 療法用モノクローナル抗体に結合する抗体の測定のためのアッセイ - Google Patents

療法用モノクローナル抗体に結合する抗体の測定のためのアッセイ Download PDF

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JP5805190B2
JP5805190B2 JP2013524450A JP2013524450A JP5805190B2 JP 5805190 B2 JP5805190 B2 JP 5805190B2 JP 2013524450 A JP2013524450 A JP 2013524450A JP 2013524450 A JP2013524450 A JP 2013524450A JP 5805190 B2 JP5805190 B2 JP 5805190B2
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tmab
antibody
sample
monoclonal antibody
igg
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JP2013536419A (ja
JP2013536419A5 (https=
Inventor
グルンエルト，ファイト・ペーター
クラウゼ，ウルスラ
クバレック，パヴェル
ロスファス，マティアス
ウプマイヤー，バーバラ
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2013524450A 2010-08-19 2011-08-17 療法用モノクローナル抗体に結合する抗体の測定のためのアッセイ Active JP5805190B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10173408 2010-08-19
EP10173408.5 2010-08-19
PCT/EP2011/064178 WO2012022774A1 (en) 2010-08-19 2011-08-17 An assay for measurement of antibodies binding to a therapeutic monoclonal antibody

Publications (3)

Publication Number Publication Date
JP2013536419A JP2013536419A (ja) 2013-09-19
JP2013536419A5 JP2013536419A5 (https=) 2014-04-24
JP5805190B2 true JP5805190B2 (ja) 2015-11-04

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JP2013524450A Active JP5805190B2 (ja) 2010-08-19 2011-08-17 療法用モノクローナル抗体に結合する抗体の測定のためのアッセイ

Country Status (7)

Country Link
US (1) US9081016B2 (https=)
EP (1) EP2606362B1 (https=)
JP (1) JP5805190B2 (https=)
CN (1) CN103109190B (https=)
CA (1) CA2802278A1 (https=)
ES (1) ES2555864T3 (https=)
WO (1) WO2012022774A1 (https=)

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CN104614535B (zh) * 2015-02-10 2017-11-28 深圳市新产业生物医学工程股份有限公司 甲状腺微粒体抗体检测试剂盒及其制备方法和应用
EP3482199A1 (en) * 2016-07-08 2019-05-15 Atonomics A/S A universal assay for determining the quantity of therapeutic monoclonal antibodies and their corresponding anti-drug-antibodies in samples
CN106093413A (zh) * 2016-07-18 2016-11-09 本·沙朗 一种抗英夫利西抗体elisa检测试剂盒和检测方法
EP3682237A1 (en) * 2017-09-15 2020-07-22 Beckman Coulter, Inc. Flow based assays for therapeutics
CN111971305A (zh) * 2018-03-27 2020-11-20 美国控股实验室公司 用于鉴定可能受益于治疗剂治疗的受试者的夹心酶联免疫吸附测定
JP7570421B2 (ja) * 2020-01-02 2024-10-21 エフ． ホフマン－ラ ロシュ アーゲー Ａｄａ応答特定アッセイ
US12560598B2 (en) 2020-03-11 2026-02-24 Genesis Intelligence, Llc Cartridge-based automated rapid test analyzer
WO2021224360A1 (en) * 2020-05-08 2021-11-11 F. Hoffmann-La Roche Ag High ionic strength dissociation assay for high drug tolerant testing
CN117590002B (zh) * 2023-11-23 2024-10-22 上海领检科技有限公司 一种TNFα抗药抗体的检测方法及检测试剂盒

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Also Published As

Publication number Publication date
ES2555864T3 (es) 2016-01-11
HK1180767A1 (en) 2013-10-25
CN103109190B (zh) 2015-07-22
JP2013536419A (ja) 2013-09-19
EP2606362A1 (en) 2013-06-26
CN103109190A (zh) 2013-05-15
US9081016B2 (en) 2015-07-14
WO2012022774A1 (en) 2012-02-23
CA2802278A1 (en) 2012-02-23
EP2606362B1 (en) 2015-09-30
US20130157892A1 (en) 2013-06-20

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