JP5795165B2 - 慢性虚血における亜硝酸塩の使用 - Google Patents
慢性虚血における亜硝酸塩の使用 Download PDFInfo
- Publication number
- JP5795165B2 JP5795165B2 JP2010534267A JP2010534267A JP5795165B2 JP 5795165 B2 JP5795165 B2 JP 5795165B2 JP 2010534267 A JP2010534267 A JP 2010534267A JP 2010534267 A JP2010534267 A JP 2010534267A JP 5795165 B2 JP5795165 B2 JP 5795165B2
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- nitrite
- ischemic
- pharmaceutical composition
- sodium nitrite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US315007P | 2007-11-15 | 2007-11-15 | |
| US61/003,150 | 2007-11-15 | ||
| PCT/US2008/083830 WO2009065142A2 (en) | 2007-11-15 | 2008-11-17 | Use of nitrite salts in chronic ischemia |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014097072A Division JP5908527B2 (ja) | 2007-11-15 | 2014-05-08 | 慢性虚血における亜硝酸塩の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011503212A JP2011503212A (ja) | 2011-01-27 |
| JP2011503212A5 JP2011503212A5 (enExample) | 2012-02-16 |
| JP5795165B2 true JP5795165B2 (ja) | 2015-10-14 |
Family
ID=40639493
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010534267A Expired - Fee Related JP5795165B2 (ja) | 2007-11-15 | 2008-11-17 | 慢性虚血における亜硝酸塩の使用 |
| JP2014097072A Expired - Fee Related JP5908527B2 (ja) | 2007-11-15 | 2014-05-08 | 慢性虚血における亜硝酸塩の使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014097072A Expired - Fee Related JP5908527B2 (ja) | 2007-11-15 | 2014-05-08 | 慢性虚血における亜硝酸塩の使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9649334B2 (enExample) |
| EP (1) | EP2219657A4 (enExample) |
| JP (2) | JP5795165B2 (enExample) |
| CN (1) | CN101939014B (enExample) |
| AU (1) | AU2008322437B2 (enExample) |
| IL (1) | IL205720A (enExample) |
| WO (1) | WO2009065142A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009065142A2 (en) | 2007-11-15 | 2009-05-22 | Biomedical Research Foundation Of Northwest Louisiana | Use of nitrite salts in chronic ischemia |
| US8568793B2 (en) | 2009-02-11 | 2013-10-29 | Hope Medical Enterprises, Inc. | Sodium nitrite-containing pharmaceutical compositions |
| WO2010147742A2 (en) * | 2009-06-18 | 2010-12-23 | Theravasc Inc. | Use of nitrite salts in treating tissue damage |
| CN107260756A (zh) | 2009-10-14 | 2017-10-20 | 瑟阿瓦斯克有限公司 | 亚硝酸盐/酯的药物制剂以及其应用 |
| US20130209584A1 (en) * | 2009-10-14 | 2013-08-15 | Theravasc Inc. | Pharmaceutical formulations of nitrite and uses thereof |
| CN105358160A (zh) | 2013-02-20 | 2016-02-24 | 瑟阿瓦斯克公司 | 亚硝酸盐的药物制剂及其用途 |
| US10517817B2 (en) | 2013-05-09 | 2019-12-31 | Syk Technologies, Llc | Deep topical systemic nitric oxide therapy apparatus and method |
| WO2017132275A1 (en) | 2016-01-27 | 2017-08-03 | Syk Technologies, Llc | Nitric oxide topical application apparatus and methods |
| KR20200083974A (ko) * | 2017-09-05 | 2020-07-09 | 엑셀 메드, 엘엘씨 | 허혈 치료용 헤파린 조성물 |
| WO2020141546A1 (en) | 2019-01-02 | 2020-07-09 | Celagenex Research (India) Pvt. Ltd. | Synergistic nutritional compositions for pain management |
| US12459820B2 (en) | 2020-06-11 | 2025-11-04 | J. W. Randolph Miller | Stabilized and NO2-inhibited nitric oxide generating gels for inhaled nitric oxide therapy |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2914446A (en) | 1958-06-26 | 1959-11-24 | Upjohn Co | Nitrite stabilized ascorbic acid-cyanocobalamin compositions |
| US4650484A (en) | 1983-02-03 | 1987-03-17 | Alza Corporation | Method for treating ischemic conditions |
| IE64726B1 (en) | 1987-11-20 | 1995-08-23 | Elan Corp Plc | Pharmaceutical formulations for preventing drug tolerance |
| US5122384A (en) | 1989-05-05 | 1992-06-16 | Kv Pharmaceutical Company | Oral once-per-day organic nitrate formulation which does not induce tolerance |
| US5278192A (en) | 1992-07-02 | 1994-01-11 | The Research Foundation Of State University Of New York | Method of vasodilator therapy for treating a patient with a condition |
| US6709681B2 (en) | 1995-02-17 | 2004-03-23 | Aberdeen University | Acidified nitrite as an antimicrobial agent |
| US20110196039A9 (en) | 1994-10-05 | 2011-08-11 | Kaesemeyer Wayne H | Controlled release arginine formulations |
| US5648101A (en) * | 1994-11-14 | 1997-07-15 | Tawashi; Rashad | Drug delivery of nitric oxide |
| US5770645A (en) | 1996-08-02 | 1998-06-23 | Duke University Medical Center | Polymers for delivering nitric oxide in vivo |
| US5994444A (en) | 1997-10-16 | 1999-11-30 | Medtronic, Inc. | Polymeric material that releases nitric oxide |
| US7371415B1 (en) | 1998-04-03 | 2008-05-13 | The Daily Wellness Company | Method and composition for improving sexual fitness |
| US7015876B1 (en) | 1998-06-03 | 2006-03-21 | Lear Corporation | Heads-up display with improved contrast |
| US6103275A (en) * | 1998-06-10 | 2000-08-15 | Nitric Oxide Solutions | Systems and methods for topical treatment with nitric oxide |
| WO2000003725A1 (en) | 1998-07-14 | 2000-01-27 | Paracelsian, Inc. | Method for identifying and confirming consistent bio-functionality of natural compositions |
| JP2002535353A (ja) | 1999-01-29 | 2002-10-22 | ロザン ファルマ ゲゼルシャフトミットベシュレンクテルハフツンク | 医薬品組成物 |
| GB9905425D0 (en) | 1999-03-09 | 1999-05-05 | Queen Mary & Westfield College | Pharmaceutical composition |
| US6314956B1 (en) | 1999-09-08 | 2001-11-13 | Duke University | Pulmonary delivery of NO group-containing compound in gas form to treat respiratory, cardiac and blood disorders |
| JP2004505056A (ja) * | 2000-07-28 | 2004-02-19 | バイオエナジー インコーポレイティド | 心血管の機能を向上する為の組成物及び方法 |
| GB0119011D0 (en) | 2001-08-03 | 2001-09-26 | Univ Aberdeen | Treatment of nail infections |
| EP1492509A1 (en) | 2001-12-18 | 2005-01-05 | ALZA Corporation | Dosage form providing time-varying patterns of drug delivery |
| EP1336602A1 (en) | 2002-02-13 | 2003-08-20 | Giovanni Scaramuzzino | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases |
| CA2379211A1 (fr) | 2002-03-28 | 2003-09-28 | Institut De Cardiologie De Montreal | Utilisation du bleu de methylene pour renverser la reaction hemodynamique exageree induite par la combinaison d'un derive nitre et du sildenafil ou d'une molecule de meme classe (inhibiteur de la phosphodiesterase) |
| WO2005004884A2 (en) | 2003-07-09 | 2005-01-20 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Use of nitrite salts for the treatment of cardiovascular conditions |
| JP2007502831A (ja) | 2003-08-20 | 2007-02-15 | ニトロメッド インコーポレーティッド | ニトロソ化およびニトロシル化心血管化合物、組成物、ならびに使用方法 |
| WO2005023189A2 (en) * | 2003-09-03 | 2005-03-17 | Pharmacia Corporation | Method of cox-2 selective inhibitor and nitric oxide-donating agent |
| US7362274B1 (en) * | 2004-07-09 | 2008-04-22 | Huan-Cheng Lien | Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna |
| US20060083824A1 (en) | 2004-10-20 | 2006-04-20 | Pbm Products Llc | Nutritional supplements for glucose intolerant individuals |
| CA2608651A1 (en) | 2005-05-24 | 2006-11-30 | Wellgen, Inc. | Compositions and methods for the prevention and treatment of conditions associated with inflammation |
| CA2641950A1 (en) | 2006-02-10 | 2007-08-23 | Mannatech, Inc. | All natural multivitamin and multimineral dietary supplement formulations for enhanced absorption and biological utilization |
| GB0607402D0 (en) | 2006-04-12 | 2006-05-24 | Barts & London Nhs Trust | Therapeutic composition and use |
| WO2007149520A2 (en) * | 2006-06-21 | 2007-12-27 | Albert Einstein College Of Medicine Of Yeshiva University | Compositions for sustained release of nitric oxide, methods of preparing same and uses thereof |
| CA2678093C (en) | 2007-02-26 | 2017-10-24 | Jon Lundberg | Performance enhancing composition and use thereof |
| KR20100014853A (ko) | 2007-02-26 | 2010-02-11 | 존 런드버그 | 아질산염 및 질산염의 신규 용도 및 이를 함유하는 조성물 |
| WO2008153762A2 (en) | 2007-05-25 | 2008-12-18 | N30 Pharmaceuticals, Llc | S-nitrosothiol formulations and storage systems |
| WO2009065142A2 (en) | 2007-11-15 | 2009-05-22 | Biomedical Research Foundation Of Northwest Louisiana | Use of nitrite salts in chronic ischemia |
| US20090196930A1 (en) | 2007-12-27 | 2009-08-06 | Aires Pharmaceuticals, Inc. | Aerosolized nitrite and nitric oxide -donating compounds and uses thereof |
| WO2010036236A1 (en) | 2008-09-23 | 2010-04-01 | Baker Hughes Incorporated | Anchor assembly |
| US8568793B2 (en) | 2009-02-11 | 2013-10-29 | Hope Medical Enterprises, Inc. | Sodium nitrite-containing pharmaceutical compositions |
| WO2010147742A2 (en) | 2009-06-18 | 2010-12-23 | Theravasc Inc. | Use of nitrite salts in treating tissue damage |
| CN107260756A (zh) * | 2009-10-14 | 2017-10-20 | 瑟阿瓦斯克有限公司 | 亚硝酸盐/酯的药物制剂以及其应用 |
| US20130209584A1 (en) | 2009-10-14 | 2013-08-15 | Theravasc Inc. | Pharmaceutical formulations of nitrite and uses thereof |
| WO2012135623A1 (en) | 2011-03-31 | 2012-10-04 | Theravasc Inc. | Use of nitrites for the treatment of cerebral amyloid angiopathy, age associated dementia, and cognitive decline |
| US20140112983A1 (en) | 2011-04-14 | 2014-04-24 | Theravasc Inc. | Nitrite compositions and uses thereof |
| US9294956B2 (en) | 2011-12-29 | 2016-03-22 | Qualcomm Incorporated | Application-server-assisted preemptive multicast bearer establishment for real-time low-latency applications |
| CN105358160A (zh) * | 2013-02-20 | 2016-02-24 | 瑟阿瓦斯克公司 | 亚硝酸盐的药物制剂及其用途 |
-
2008
- 2008-11-17 WO PCT/US2008/083830 patent/WO2009065142A2/en not_active Ceased
- 2008-11-17 US US12/741,436 patent/US9649334B2/en active Active
- 2008-11-17 EP EP08849380.4A patent/EP2219657A4/en not_active Withdrawn
- 2008-11-17 AU AU2008322437A patent/AU2008322437B2/en not_active Ceased
- 2008-11-17 CN CN200880116483.4A patent/CN101939014B/zh not_active Expired - Fee Related
- 2008-11-17 JP JP2010534267A patent/JP5795165B2/ja not_active Expired - Fee Related
-
2010
- 2010-05-12 IL IL205720A patent/IL205720A/en active IP Right Grant
-
2014
- 2014-05-08 JP JP2014097072A patent/JP5908527B2/ja not_active Expired - Fee Related
-
2017
- 2017-04-10 US US15/483,187 patent/US10864229B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014139255A (ja) | 2014-07-31 |
| CN101939014A (zh) | 2011-01-05 |
| JP5908527B2 (ja) | 2016-04-26 |
| US10864229B2 (en) | 2020-12-15 |
| US20110311653A1 (en) | 2011-12-22 |
| IL205720A0 (en) | 2010-11-30 |
| IL205720A (en) | 2015-08-31 |
| WO2009065142A2 (en) | 2009-05-22 |
| JP2011503212A (ja) | 2011-01-27 |
| AU2008322437B2 (en) | 2013-11-07 |
| EP2219657A4 (en) | 2020-01-08 |
| EP2219657A2 (en) | 2010-08-25 |
| US20170312310A1 (en) | 2017-11-02 |
| AU2008322437A1 (en) | 2009-05-22 |
| US9649334B2 (en) | 2017-05-16 |
| CN101939014B (zh) | 2016-04-27 |
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