AU2008322437B2 - Use of nitrite salts in chronic ischemia - Google Patents

Use of nitrite salts in chronic ischemia Download PDF

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Publication number
AU2008322437B2
AU2008322437B2 AU2008322437A AU2008322437A AU2008322437B2 AU 2008322437 B2 AU2008322437 B2 AU 2008322437B2 AU 2008322437 A AU2008322437 A AU 2008322437A AU 2008322437 A AU2008322437 A AU 2008322437A AU 2008322437 B2 AU2008322437 B2 AU 2008322437B2
Authority
AU
Australia
Prior art keywords
tissue
nitrite
ischemic
chronic
ischemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2008322437A
Other languages
English (en)
Other versions
AU2008322437A1 (en
Inventor
Christopher Kevil
David Lefer
Rakesh Patel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UAB Research Foundation
Louisiana State University
Original Assignee
UAB Research Foundation
Louisiana State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UAB Research Foundation, Louisiana State University filed Critical UAB Research Foundation
Publication of AU2008322437A1 publication Critical patent/AU2008322437A1/en
Assigned to THE UAB RESEARCH FOUNDATION, LOUISIANA STATE UNIVERSITY reassignment THE UAB RESEARCH FOUNDATION Amend patent request/document other than specification (104) Assignors: BIOMEDICAL RESEARCH FOUNDATION OF NORTHWEST LOUISIANA, LOUISIANA STATE UNIVERSITY, The UAB Research Foundation\
Application granted granted Critical
Publication of AU2008322437B2 publication Critical patent/AU2008322437B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2008322437A 2007-11-15 2008-11-17 Use of nitrite salts in chronic ischemia Ceased AU2008322437B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US315007P 2007-11-15 2007-11-15
US61/003,150 2007-11-15
PCT/US2008/083830 WO2009065142A2 (en) 2007-11-15 2008-11-17 Use of nitrite salts in chronic ischemia

Publications (2)

Publication Number Publication Date
AU2008322437A1 AU2008322437A1 (en) 2009-05-22
AU2008322437B2 true AU2008322437B2 (en) 2013-11-07

Family

ID=40639493

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008322437A Ceased AU2008322437B2 (en) 2007-11-15 2008-11-17 Use of nitrite salts in chronic ischemia

Country Status (7)

Country Link
US (2) US9649334B2 (enExample)
EP (1) EP2219657A4 (enExample)
JP (2) JP5795165B2 (enExample)
CN (1) CN101939014B (enExample)
AU (1) AU2008322437B2 (enExample)
IL (1) IL205720A (enExample)
WO (1) WO2009065142A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009065142A2 (en) 2007-11-15 2009-05-22 Biomedical Research Foundation Of Northwest Louisiana Use of nitrite salts in chronic ischemia
US8568793B2 (en) * 2009-02-11 2013-10-29 Hope Medical Enterprises, Inc. Sodium nitrite-containing pharmaceutical compositions
WO2010147742A2 (en) * 2009-06-18 2010-12-23 Theravasc Inc. Use of nitrite salts in treating tissue damage
US20130209584A1 (en) * 2009-10-14 2013-08-15 Theravasc Inc. Pharmaceutical formulations of nitrite and uses thereof
EP2488035B1 (en) * 2009-10-14 2017-04-26 Theravasc Inc. Pharmaceutical formulations of nitrite and uses thereof
WO2014130691A2 (en) * 2013-02-20 2014-08-28 Theravasc Inc. Pharmaceutical formulations of nitrite and uses thereof
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
FI3407900T3 (fi) 2016-01-27 2024-03-21 Syk Tech Llc Laitteisto typpioksidin paikalliseksi levittämiseksi ja menetelmiä
AU2018330051B2 (en) 2017-09-05 2025-03-06 National Cheng Kung University Heparin composition for treating ischemia
CA3123524C (en) 2019-01-02 2024-01-23 Celagenex Research (India) Pvt. Ltd. Synergistic nutritional compositions for pain management
US12459820B2 (en) 2020-06-11 2025-11-04 J. W. Randolph Miller Stabilized and NO2-inhibited nitric oxide generating gels for inhaled nitric oxide therapy

Citations (1)

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Publication number Priority date Publication date Assignee Title
US20060182815A1 (en) * 2004-07-09 2006-08-17 Use of nitrite salts for the treatment of cardiovascular conditions

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US4650484A (en) 1983-02-03 1987-03-17 Alza Corporation Method for treating ischemic conditions
IE64726B1 (en) 1987-11-20 1995-08-23 Elan Corp Plc Pharmaceutical formulations for preventing drug tolerance
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US6709681B2 (en) 1995-02-17 2004-03-23 Aberdeen University Acidified nitrite as an antimicrobial agent
US20110196039A9 (en) 1994-10-05 2011-08-11 Kaesemeyer Wayne H Controlled release arginine formulations
US5648101A (en) * 1994-11-14 1997-07-15 Tawashi; Rashad Drug delivery of nitric oxide
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CA2379211A1 (fr) 2002-03-28 2003-09-28 Institut De Cardiologie De Montreal Utilisation du bleu de methylene pour renverser la reaction hemodynamique exageree induite par la combinaison d'un derive nitre et du sildenafil ou d'une molecule de meme classe (inhibiteur de la phosphodiesterase)
AU2004257693B8 (en) * 2003-07-09 2009-08-13 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of nitrite salts for the treatment of cardiovascular conditions
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WO2010147742A2 (en) 2009-06-18 2010-12-23 Theravasc Inc. Use of nitrite salts in treating tissue damage
EP2488035B1 (en) 2009-10-14 2017-04-26 Theravasc Inc. Pharmaceutical formulations of nitrite and uses thereof
US20130209584A1 (en) 2009-10-14 2013-08-15 Theravasc Inc. Pharmaceutical formulations of nitrite and uses thereof
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Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060182815A1 (en) * 2004-07-09 2006-08-17 Use of nitrite salts for the treatment of cardiovascular conditions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Jung, KH et al (2006) Stroke. Volume 37. Pages 27442750 *

Also Published As

Publication number Publication date
US9649334B2 (en) 2017-05-16
JP2011503212A (ja) 2011-01-27
US10864229B2 (en) 2020-12-15
US20170312310A1 (en) 2017-11-02
JP5795165B2 (ja) 2015-10-14
JP5908527B2 (ja) 2016-04-26
EP2219657A2 (en) 2010-08-25
CN101939014A (zh) 2011-01-05
AU2008322437A1 (en) 2009-05-22
JP2014139255A (ja) 2014-07-31
CN101939014B (zh) 2016-04-27
IL205720A (en) 2015-08-31
WO2009065142A2 (en) 2009-05-22
US20110311653A1 (en) 2011-12-22
EP2219657A4 (en) 2020-01-08
IL205720A0 (en) 2010-11-30

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