JP5785085B2 - 癒着を処置又は防止するためのポリペプチド - Google Patents
癒着を処置又は防止するためのポリペプチド Download PDFInfo
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- JP5785085B2 JP5785085B2 JP2011533273A JP2011533273A JP5785085B2 JP 5785085 B2 JP5785085 B2 JP 5785085B2 JP 2011533273 A JP2011533273 A JP 2011533273A JP 2011533273 A JP2011533273 A JP 2011533273A JP 5785085 B2 JP5785085 B2 JP 5785085B2
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| PCT/US2009/061345 WO2010065206A1 (en) | 2008-10-20 | 2009-10-20 | Polypeptide for treating or preventing adhesions |
Publications (3)
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| JP2012506442A JP2012506442A (ja) | 2012-03-15 |
| JP2012506442A5 JP2012506442A5 (enExample) | 2012-12-06 |
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| EP2617431B1 (en) | 2007-01-10 | 2017-04-12 | Purdue Research Foundation | Polypeptide inhibitors of HSP27 kinase and uses therefor |
| JP5703466B2 (ja) | 2007-08-07 | 2015-04-22 | パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ | キナーゼ阻害薬およびその使用 |
| BRPI0922448A2 (pt) | 2008-12-10 | 2021-02-17 | Purdue Research Foundation | inibidor com base em peptídeo penetrante celular de quinases |
| WO2011017132A2 (en) | 2009-07-27 | 2011-02-10 | Purdue Research, Foundation | Mk2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration |
| US20110288036A1 (en) * | 2010-05-24 | 2011-11-24 | Cynthia Lander | Methods for Treating or Preventing Vascular Graft Failure |
| US9890200B2 (en) | 2011-04-12 | 2018-02-13 | Moerae Matrix, Inc. | Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition |
| ES2711670T3 (es) | 2011-04-12 | 2019-05-06 | Moerae Matrix Inc | Composiciones y métodos para la prevención o tratamiento de la fibrosis pulmonar |
| US9452218B2 (en) | 2012-03-09 | 2016-09-27 | Purdue Research Foundation | Compositions and methods for delivery of kinase inhibiting peptides |
| WO2013142374A1 (en) | 2012-03-23 | 2013-09-26 | Amirobe, Inc. | Compositions and uses of antimicrobial materials with tissue-compatible properties |
| US20140072613A1 (en) * | 2012-09-10 | 2014-03-13 | Cynthia Lander | Compositions and Methods for Treating Cutaneous Scarring |
| WO2016061145A1 (en) * | 2014-10-13 | 2016-04-21 | Symic Biomedical, Inc. | Synthetic proteoglycans for preventing tissue adhesion |
| BR112017010238A2 (pt) * | 2014-11-17 | 2018-02-06 | Moerae Matrix, Inc. | composições e métodos para prevenir ou tratar doenças, condições ou processos caracterizados por proliferação de fibroblastos e a deposição aberrante de matriz extracelular |
| MX2017008994A (es) * | 2015-01-08 | 2018-09-18 | Moerae Matrix Inc | Formulacion de peptidos inhibidores mk2. |
| BR112017019343A2 (pt) | 2015-03-12 | 2018-05-02 | Moerae Matrix Inc | uso de composições contendo peptídeo inibidor de mk2 para tratamento de câncer de pulmão de células não pequenas com as mesmas |
| KR20200018400A (ko) | 2017-04-06 | 2020-02-19 | 아미크로베, 인코포레이티드. | 개선된 성능 및 안전성을 가진 국소적으로 적용된 항균제의 조성물 및 용도 |
| RU2741247C1 (ru) * | 2020-10-13 | 2021-01-22 | федеральное государственное бюджетное образовательное учреждение высшего образования "Ростовский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РостГМУ Минздрава России) | Способ профилактики перитонеальных спаек женского таза |
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| GB1521000A (en) | 1975-06-13 | 1978-08-09 | Syntex Puerto Rico Inc | Inhalation device |
| US4227522A (en) | 1978-09-05 | 1980-10-14 | Syntex Puerto Rico, Inc. | Inhalation device |
| US4192309A (en) | 1978-09-05 | 1980-03-11 | Syntex Puerto Rico, Inc. | Inhalation device with capsule opener |
| US4778054A (en) | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| ES286422Y (es) | 1982-10-08 | 1986-09-16 | Glaxo Group Limited | Dispositivo para administrar medicamentos a pacientes |
| AT396872B (de) | 1985-07-30 | 1993-12-27 | Glaxo Group Ltd | Gerät zur verabreichung von medikamenten in pulverform |
| JPH05963A (ja) | 1990-04-13 | 1993-01-08 | Toray Ind Inc | ポリペプチド類組成物 |
| WO1993022443A1 (en) | 1992-04-24 | 1993-11-11 | Sri International | In vivo homologous sequence targeting in eukaryotic cells |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| KR100386337B1 (ko) | 1993-12-09 | 2004-03-24 | 토마스 제퍼슨 대학교 | 진핵세포에서부위-특이적돌연변이를위한화합물과그방법 |
| AU2003260668A1 (en) | 2002-04-01 | 2003-10-20 | Arizona Board Of Regents, A Body Corporate Acting On Behalf Of Arizona State University | Biological affinity based delivery systems |
| US8008093B2 (en) * | 2004-12-02 | 2011-08-30 | The University Of North Carolina At Chapel Hill | Inhibition of Hsp27 phosphorylation for the treatment of blistering disorders |
| AU2006236441B2 (en) * | 2005-04-15 | 2011-09-01 | Arizona Cancer Therapeutics, Llc | Therapeutic peptides for the treatment of metastatic cancer |
| EP2617431B1 (en) * | 2007-01-10 | 2017-04-12 | Purdue Research Foundation | Polypeptide inhibitors of HSP27 kinase and uses therefor |
| US20080293640A1 (en) * | 2007-01-10 | 2008-11-27 | Arizona Board of Regents, A body Corporate, of the State of Arizona, acting for and on behalf of | Polypeptide inhibitors of HSP27 kinase and uses therefor |
| WO2008109794A2 (en) * | 2007-03-08 | 2008-09-12 | Tufts Medical Center | The role of the mk2 pathway in treating fibrosis and scarring |
| JP5703466B2 (ja) * | 2007-08-07 | 2015-04-22 | パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ | キナーゼ阻害薬およびその使用 |
| WO2009123759A2 (en) * | 2008-04-02 | 2009-10-08 | Moerae Matrix, Inc. | Therapeutic uses of biocompatible biogel compositions |
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2009
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- 2009-10-20 JP JP2011533273A patent/JP5785085B2/ja not_active Expired - Fee Related
- 2009-10-20 US US12/582,516 patent/US9034815B2/en not_active Expired - Fee Related
- 2009-10-20 KR KR1020167036610A patent/KR20170001756A/ko not_active Ceased
- 2009-10-20 AU AU2009322865A patent/AU2009322865B2/en not_active Ceased
- 2009-10-20 EP EP09830789.5A patent/EP2349310B1/en not_active Not-in-force
- 2009-10-20 WO PCT/US2009/061345 patent/WO2010065206A1/en not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| KR20170001756A (ko) | 2017-01-04 |
| KR20110095867A (ko) | 2011-08-25 |
| US20130101671A9 (en) | 2013-04-25 |
| EP2349310B1 (en) | 2014-07-23 |
| BRPI0919759A2 (pt) | 2017-03-21 |
| KR101884616B1 (ko) | 2018-08-06 |
| CN102256613B (zh) | 2014-09-10 |
| ES2507496T3 (es) | 2014-10-15 |
| DK2349310T3 (da) | 2014-08-11 |
| EP2349310A1 (en) | 2011-08-03 |
| AU2009322865A1 (en) | 2010-06-10 |
| US20100098760A1 (en) | 2010-04-22 |
| WO2010065206A1 (en) | 2010-06-10 |
| AU2009322865B2 (en) | 2013-07-18 |
| JP2012506442A (ja) | 2012-03-15 |
| CA2741302A1 (en) | 2010-06-10 |
| EP2349310A4 (en) | 2012-11-21 |
| CA2741302C (en) | 2017-02-28 |
| CN102256613A (zh) | 2011-11-23 |
| US9034815B2 (en) | 2015-05-19 |
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| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
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| LAPS | Cancellation because of no payment of annual fees |