JP5774990B2 - 蛍光標識及び可溶性消光体を使用する標的変異体の検出 - Google Patents

蛍光標識及び可溶性消光体を使用する標的変異体の検出 Download PDF

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JP5774990B2
JP5774990B2 JP2011527239A JP2011527239A JP5774990B2 JP 5774990 B2 JP5774990 B2 JP 5774990B2 JP 2011527239 A JP2011527239 A JP 2011527239A JP 2011527239 A JP2011527239 A JP 2011527239A JP 5774990 B2 JP5774990 B2 JP 5774990B2
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nucleic acid
label
labeled oligonucleotide
target nucleic
labeled
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JP2012502638A5 (enExample
JP2012502638A (ja
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ゴードン ウィル，スティーブン
ゴードン ウィル，スティーブン
ピー． グプタ，アマル
ピー． グプタ，アマル
ゲイヤー，ローラ
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP2011527239A 2008-09-18 2009-09-16 蛍光標識及び可溶性消光体を使用する標的変異体の検出 Active JP5774990B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9818608P 2008-09-18 2008-09-18
US61/098,186 2008-09-18
PCT/EP2009/006688 WO2010031539A1 (en) 2008-09-18 2009-09-16 Detection of target variants using a fluorescent labeland and a soluble quencher

Publications (3)

Publication Number Publication Date
JP2012502638A JP2012502638A (ja) 2012-02-02
JP2012502638A5 JP2012502638A5 (enExample) 2012-06-07
JP5774990B2 true JP5774990B2 (ja) 2015-09-09

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ID=41256038

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JP2011527239A Active JP5774990B2 (ja) 2008-09-18 2009-09-16 蛍光標識及び可溶性消光体を使用する標的変異体の検出

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US (1) US8658366B2 (enExample)
EP (1) EP2347012B1 (enExample)
JP (1) JP5774990B2 (enExample)
CA (1) CA2733653C (enExample)
ES (1) ES2629460T3 (enExample)
WO (1) WO2010031539A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2971169A1 (en) * 2014-12-30 2016-07-07 Telomere Diagnostics, Inc. Multiplex quantitative pcr
CN114250274A (zh) 2015-04-24 2022-03-29 阿提拉生物系统公司 利用有限核苷酸组成的引物扩增

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9918237D0 (en) 1999-08-04 1999-10-06 Secr Defence Detection system
GB0112868D0 (en) 2001-05-25 2001-07-18 Secr Defence Detection system
GB0223563D0 (en) 2002-10-10 2002-11-20 Secr Defence Detection system
US8067208B2 (en) * 2005-06-30 2011-11-29 Roche Molecular Systems, Inc. Probes and methods for hepatitis C virus typing using multidimensional probe analysis
US7785786B2 (en) 2006-01-23 2010-08-31 Quest Diagnostics Investments Incorporated Methods for detecting nucleic acids using multiple signals
GB0603190D0 (en) 2006-02-16 2006-03-29 Enigma Diagnostics Ltd Detection system

Also Published As

Publication number Publication date
ES2629460T3 (es) 2017-08-09
EP2347012A1 (en) 2011-07-27
US20100124744A1 (en) 2010-05-20
CA2733653C (en) 2016-04-26
CA2733653A1 (en) 2010-03-25
JP2012502638A (ja) 2012-02-02
WO2010031539A1 (en) 2010-03-25
EP2347012B1 (en) 2017-04-19
US8658366B2 (en) 2014-02-25

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