JP5770690B2 - 無菌乳およびその組成物を得る方法 - Google Patents
無菌乳およびその組成物を得る方法 Download PDFInfo
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- JP5770690B2 JP5770690B2 JP2012162801A JP2012162801A JP5770690B2 JP 5770690 B2 JP5770690 B2 JP 5770690B2 JP 2012162801 A JP2012162801 A JP 2012162801A JP 2012162801 A JP2012162801 A JP 2012162801A JP 5770690 B2 JP5770690 B2 JP 5770690B2
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- 108700012359 toxins Proteins 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 235000019163 vitamin B12 Nutrition 0.000 description 1
- 239000011715 vitamin B12 Substances 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 238000003260 vortexing Methods 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- 239000002478 γ-tocopherol Substances 0.000 description 1
- QUEDXNHFTDJVIY-DQCZWYHMSA-N γ-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-DQCZWYHMSA-N 0.000 description 1
- 239000002446 δ-tocopherol Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
- A23C9/206—Colostrum; Human milk
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
- A23B11/00—Preservation of milk or dairy products
- A23B11/10—Preservation of milk or milk preparations
- A23B11/12—Preservation of milk or milk preparations by heating
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
- A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
- A23C9/1422—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by ultrafiltration, microfiltration or diafiltration of milk, e.g. for separating protein and lactose; Treatment of the UF permeate
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C2210/00—Physical treatment of dairy products
- A23C2210/25—Separating and blending
- A23C2210/252—Separating a milk product in at least two fractions followed by treatment of at least one of the fractions and remixing at least part of the two fractions
Landscapes
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Water Supply & Treatment (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Dairy Products (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Description
カロリー 8.5
脂肪合計 0.44g
ナトリウム 2.3mg
カリウム 6.3mg
合計 炭水化物 0.79g
糖類 0.64g
タンパク質 0.31g
ビタミンA 21.1IU
ビタミンC <0.10mg
カルシウム 8.0mg
鉄 13.3μg
リン 3.8mg
マグネシウム 0.74mg
塩素 5.0mg
亜鉛 0.12μg
銅 17.3μg
マンガン <6.2μg
オスモル濃度 −322mOsm/Kg H2O
カロリー 2.7
脂肪合計 0.15g
ナトリウム 1.2mg
カリウム 2.3mg
合計 炭水化物 0.21g
糖類 0.15g
タンパク質 0.10g
ビタミンA 5.5IU
ビタミンC <0.02mg
カルシウム 8.9mg
鉄 0.01mg
リン 3.6mg
マグネシウム 0.38mg
塩素 0.4mg
亜鉛 0.05mg
銅 2.7μg
マンガン <1.3μg
オスモル濃度 −343mOsm/Kg H2O(生乳との混合時)
Claims (15)
- 20〜70mg/mlのヒト乳タンパク質成分と、
35〜85mg/mlのヒト乳脂肪成分と、
70〜115mg/mlのヒト乳炭水化物成分と
を含むヒト乳強化剤組成物であって、ヒトIgAを含むヒト乳強化剤組成物。 - 50mg/mlのヒト乳タンパク質成分と、
75mg/mlのヒト乳脂肪成分と、
105mg/mlのヒト乳炭水化物成分と
を含む、請求項1に記載のヒト乳強化剤組成物。 - 31mg/mlのヒト乳タンパク質成分と、
44mg/mlのヒト乳脂肪成分と、
79mg/mlのヒト乳炭水化物成分と
を含む、請求項1に記載のヒト乳強化剤組成物。 - ビタミンA、ビタミンC、カルシウム、鉄、リン、マグネシウム、塩素、亜鉛、銅、マンガン、ナトリウム、カリウム、リゾチーム、ラクトフェリン、ビタミンB6、およびこれらの任意の組合せからなる群より選択される成分をさらに含む、請求項1に記載のヒト乳強化剤組成物。
- 前記ヒトIgAが、分泌型IgAを含む、請求項1に記載のヒト乳強化剤組成物。
- 前記IgAが、100〜600mg/mlである、請求項1に記載のヒト乳強化剤組成物。
- 前記IgAが、230mg/mlである、請求項1に記載のヒト乳強化剤組成物。
- 前記リゾチームが、22,000IU/mlである、請求項4に記載のヒト乳強化剤組成物。
- 前記ラクトフェリンが、0.33mg/mlである、請求項4に記載のヒト乳強化剤組成物。
- 請求項1に記載のヒト乳強化剤組成物、および前記ヒト乳強化剤組成物を生ヒト乳と混合して混合配合物を得るための計量ボトルを含み、前記混合配合物は前記ヒト乳強化剤組成物を含まない生乳よりも4cal/オンス多く含む、キット。
- 生ヒト乳の栄養含有量を測定することと、
請求項1に記載のヒト乳強化剤組成物を生乳に添加して生乳の栄養価を4カロリー/オンス増加させること
とを含む、栄養乳組成物を得る方法。 - 少なくとも2.1g/dLのヒト乳タンパク質、およびヒト乳脂肪を含む、ドナーの自己生乳および同種異系乳組成物を含むヒト乳強化剤組成物。
- 前記ヒト乳タンパク質が、凍結乾燥されていないヒト乳タンパク質である、請求項12に記載のヒト乳強化剤組成物。
- 2.1g/dL(21mg/ml)〜3.75g/dL(37.5mg/ml)のヒト乳タンパク質を含む、請求項12に記載のヒト乳強化剤組成物。
- 2.1%〜3.75%のヒト乳タンパク質を含む、請求項12に記載のヒト乳強化剤組成物。
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US84137106P | 2006-08-30 | 2006-08-30 | |
US60/841,371 | 2006-08-30 | ||
US86774806P | 2006-11-29 | 2006-11-29 | |
US60/867,748 | 2006-11-29 |
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US (8) | US9149052B2 (ja) |
EP (1) | EP2063722B1 (ja) |
JP (2) | JP5448819B2 (ja) |
ES (1) | ES2634613T3 (ja) |
PT (1) | PT2099321T (ja) |
WO (1) | WO2008027572A1 (ja) |
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CN101626697A (zh) | 2006-11-29 | 2010-01-13 | 普罗莱克塔生物科学公司 | 人乳组合物及其制备和使用方法 |
ES2396571T3 (es) | 2006-12-08 | 2013-02-22 | Prolacta Bioscience, Inc. | Composiciones de lípidos humanos y procedimientos de preparación y utilización de los mismos |
WO2010065652A1 (en) * | 2008-12-02 | 2010-06-10 | Prolacta Bioscience, Inc. | Human milk permeate compositions and methods of making and using same |
US10820604B2 (en) | 2011-08-03 | 2020-11-03 | Prolacta Bioscience, Inc. | Microfiltration of human milk to reduce bacterial contamination |
CN103906435B (zh) * | 2011-10-18 | 2016-11-23 | 雀巢产品技术援助有限公司 | 用于促进镁吸收和/或镁保留的组合物 |
US9458230B2 (en) * | 2013-01-04 | 2016-10-04 | Wisconsin Alumni Research Foundation | Secretory IGA compositions, methods of making and methods of use thereof |
US20140271980A1 (en) * | 2013-03-13 | 2014-09-18 | Prolacta Bioscience | Adulteration testing of human milk |
CN105246342A (zh) | 2013-03-13 | 2016-01-13 | 普罗莱克塔生物科学公司 | 高脂人乳产品 |
ITMI20131690A1 (it) * | 2013-10-14 | 2015-04-15 | Consiglio Nazionale Ricerche | Composizione alimentare. |
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IL260327B2 (en) | 2015-12-30 | 2023-10-01 | Prolacta Bioscience Inc | Human milk products useful in pre- and post-operative care |
CN109952031A (zh) * | 2016-10-04 | 2019-06-28 | Imb公司 | 用于产生灭菌的人乳产品的方法和系统 |
WO2020123121A1 (en) * | 2018-12-11 | 2020-06-18 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Methods of screening antibodies for treating and/or preventing necrotizing enterocolitis (nec) |
MX2021010118A (es) | 2019-02-22 | 2021-11-12 | Aquero Canada Ltd | Composiciones lacteas fortificadas y sus procesos de preparacion. |
MX2022002949A (es) | 2019-09-24 | 2022-04-06 | Prolacta Bioscience Inc | Composiciones y metodos para el tratamiento de enfermedades inflamatorias e inmunes. |
WO2022148549A1 (en) | 2020-01-14 | 2022-07-14 | Babylat Gmbh | Apparatus and method for obtaining protein-enriched fractions from breast milk |
WO2021146561A1 (en) | 2020-01-17 | 2021-07-22 | Prolacta Bioscience, Inc. | Feeding protocol for optimal growth of preterm infants |
CN116322371A (zh) | 2020-08-14 | 2023-06-23 | 普罗莱克塔生物科学公司 | 与细菌疗法一起使用的人乳寡糖组合物 |
KR20230131228A (ko) | 2021-01-12 | 2023-09-12 | 프롤랙타 바이오사이언스, 인코포레이티드 | 신바이오틱 치료 요법 |
US20240122952A1 (en) | 2021-01-22 | 2024-04-18 | Prolacta Bioscience, Inc. | Topical human milk formulations |
WO2024130119A2 (en) | 2022-12-16 | 2024-06-20 | Prolacta Bioscience, Inc. | Synbiotic compositions for short chain fatty acid production |
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PT2099321T (pt) | 2017-07-21 |
US20170347675A1 (en) | 2017-12-07 |
US20190327994A1 (en) | 2019-10-31 |
US20190075809A1 (en) | 2019-03-14 |
EP2063722A1 (en) | 2009-06-03 |
WO2008027572A1 (en) | 2008-03-06 |
EP2063722A4 (en) | 2011-05-18 |
US20250185679A1 (en) | 2025-06-12 |
JP5448819B2 (ja) | 2014-03-19 |
US20110256269A1 (en) | 2011-10-20 |
US20160050949A1 (en) | 2016-02-25 |
US20220232844A1 (en) | 2022-07-28 |
US20190053508A1 (en) | 2019-02-21 |
JP2010502186A (ja) | 2010-01-28 |
ES2634613T3 (es) | 2017-09-28 |
JP2012231793A (ja) | 2012-11-29 |
EP2063722B1 (en) | 2017-05-03 |
US9149052B2 (en) | 2015-10-06 |
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