JP5769036B2 - 空間選択的迷走神経刺激のためのシステム - Google Patents

空間選択的迷走神経刺激のためのシステム Download PDF

Info

Publication number
JP5769036B2
JP5769036B2 JP2013513215A JP2013513215A JP5769036B2 JP 5769036 B2 JP5769036 B2 JP 5769036B2 JP 2013513215 A JP2013513215 A JP 2013513215A JP 2013513215 A JP2013513215 A JP 2013513215A JP 5769036 B2 JP5769036 B2 JP 5769036B2
Authority
JP
Japan
Prior art keywords
stimulation
pulse
electrical stimulation
electrode
vagus nerve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2013513215A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013530747A (ja
JP2013530747A5 (https=
Inventor
ポール ビー ヨー
ポール ビー ヨー
ウォーレン エム グリル
ウォーレン エム グリル
オルドニェス ファン ガブリエル ヒンカピー
オルドニェス ファン ガブリエル ヒンカピー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardiac Pacemakers Inc
Duke University
Original Assignee
Cardiac Pacemakers Inc
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiac Pacemakers Inc, Duke University filed Critical Cardiac Pacemakers Inc
Publication of JP2013530747A publication Critical patent/JP2013530747A/ja
Publication of JP2013530747A5 publication Critical patent/JP2013530747A5/ja
Application granted granted Critical
Publication of JP5769036B2 publication Critical patent/JP5769036B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114Cardiac control, e.g. by vagal stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128Control systems
    • A61N1/36146Control systems specified by the stimulation parameters
    • A61N1/36167Timing, e.g. stimulation onset
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/388Nerve conduction study, e.g. detecting action potential of peripheral nerves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/389Electromyography [EMG]
    • A61B5/395Details of stimulation, e.g. nerve stimulation to elicit EMG response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4029Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551Spinal or peripheral nerve electrodes
    • A61N1/0556Cuff electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Electrotherapy Devices (AREA)
JP2013513215A 2010-06-03 2011-05-24 空間選択的迷走神経刺激のためのシステム Expired - Fee Related JP5769036B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35118110P 2010-06-03 2010-06-03
US61/351,181 2010-06-03
PCT/US2011/037726 WO2011153024A1 (en) 2010-06-03 2011-05-24 System for spatially selective vagus nerve stimulation

Publications (3)

Publication Number Publication Date
JP2013530747A JP2013530747A (ja) 2013-08-01
JP2013530747A5 JP2013530747A5 (https=) 2014-07-10
JP5769036B2 true JP5769036B2 (ja) 2015-08-26

Family

ID=44627009

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013513215A Expired - Fee Related JP5769036B2 (ja) 2010-06-03 2011-05-24 空間選択的迷走神経刺激のためのシステム

Country Status (4)

Country Link
US (2) US8509919B2 (https=)
EP (1) EP2575961B1 (https=)
JP (1) JP5769036B2 (https=)
WO (1) WO2011153024A1 (https=)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8862243B2 (en) 2005-07-25 2014-10-14 Rainbow Medical Ltd. Electrical stimulation of blood vessels
ES2430613T3 (es) 2007-01-29 2013-11-21 Simon Fraser University Aparato de neuroestimulación transvascular
EP2185237A1 (en) 2007-09-13 2010-05-19 Cardiac Pacemakers, Inc. Systems for avoiding neural stimulation habituation
US8538535B2 (en) 2010-08-05 2013-09-17 Rainbow Medical Ltd. Enhancing perfusion by contraction
US9005106B2 (en) 2008-01-31 2015-04-14 Enopace Biomedical Ltd Intra-aortic electrical counterpulsation
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
WO2010144578A2 (en) 2009-06-09 2010-12-16 Setpoint Medical Corporation Nerve cuff with pocket for leadless stimulator
WO2014169145A1 (en) 2013-04-10 2014-10-16 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
CN105126248B (zh) 2009-12-23 2018-06-12 赛博恩特医疗器械公司 用于治疗慢性炎症的神经刺激设备和系统
EP2575961B1 (en) 2010-06-03 2018-08-29 Cardiac Pacemakers, Inc. System for spatially selective vagus nerve stimulation
US12172017B2 (en) 2011-05-09 2024-12-24 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
US9980645B1 (en) * 2011-06-21 2018-05-29 Case Western Reserve University High-contact density electrode and fabrication technique for an implantable cuff design
EP2872070B1 (en) 2011-09-09 2018-02-07 Enopace Biomedical Ltd. Wireless endovascular stent-based electrodes
CN104271195B (zh) 2012-03-05 2017-04-19 西蒙·弗雷瑟大学 经血管神经刺激设备及方法
JP6133393B2 (ja) * 2012-03-19 2017-05-24 カーディアック ペースメイカーズ, インコーポレイテッド 神経損傷をモニタするためのシステム及び方法
WO2013188965A1 (en) 2012-06-21 2013-12-27 Simon Fraser University Transvascular diaphragm pacing systems and methods of use
CN105899166B (zh) 2013-11-06 2018-07-06 伊诺佩斯生医有限公司 无线型血管内基于支架的电极
CN105873630B (zh) 2013-11-22 2020-01-03 隆佩瑟尔医疗公司 用于通过经血管神经刺激辅助呼吸的装置和方法
EP3096835B1 (en) 2014-01-21 2019-08-07 Lungpacer Medical Inc. Systems for optimization of multi-electrode nerve pacing
US9974597B2 (en) 2014-03-19 2018-05-22 Boston Scientific Scimed, Inc. Systems and methods for assessing and treating tissue
EP2946806B1 (fr) 2014-05-19 2016-07-27 Sorin CRM SAS Dispositif médical implantable actif à optimisation automatique de la configuration d'une sonde de stimulation multi-électrode, notamment d'une sonde de stimulation sélective du nerf vague
US9782584B2 (en) 2014-06-13 2017-10-10 Nervana, LLC Transcutaneous electrostimulator and methods for electric stimulation
US10130809B2 (en) 2014-06-13 2018-11-20 Nervana, LLC Transcutaneous electrostimulator and methods for electric stimulation
US10646715B2 (en) 2014-07-23 2020-05-12 United States Government As Represented By The Department Of Veterans Affairs Parasympathetic activation by vagus nerve stimulation
CN107073258B (zh) 2014-08-15 2020-02-21 艾克索尼克斯调制技术股份有限公司 用于基于神经定位来进行神经刺激电极配置的系统和方法
CN106999709B (zh) 2014-08-15 2021-07-09 艾克索尼克斯股份有限公司 用于与可植入神经刺激器一起使用的集成肌电图临床医生程控器
WO2016025913A1 (en) 2014-08-15 2016-02-18 Axonics Modulation Technologies, Inc. Electromyographic lead positioning and stimulation titration in a nerve stimulation system for treatment of overactive bladder
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
CN107847180A (zh) * 2015-05-08 2018-03-27 杜克大学 脊髓刺激系统及方法
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
CN108882885A (zh) 2016-01-20 2018-11-23 赛博恩特医疗器械公司 迷走神经刺激的控制
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
US10293164B2 (en) 2017-05-26 2019-05-21 Lungpacer Medical Inc. Apparatus and methods for assisted breathing by transvascular nerve stimulation
JP7184370B2 (ja) 2017-06-30 2022-12-06 ラングペーサー メディカル インコーポレイテッド 認知障害の予防、緩和、及び/または治療のための装置
US10195429B1 (en) 2017-08-02 2019-02-05 Lungpacer Medical Inc. Systems and methods for intravascular catheter positioning and/or nerve stimulation
US10940308B2 (en) 2017-08-04 2021-03-09 Lungpacer Medical Inc. Systems and methods for trans-esophageal sympathetic ganglion recruitment
US11173307B2 (en) 2017-08-14 2021-11-16 Setpoint Medical Corporation Vagus nerve stimulation pre-screening test
US20190175908A1 (en) 2017-12-11 2019-06-13 Lungpacer Medical Inc. Systems and methods for strengthening a respiratory muscle
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
WO2020097331A1 (en) 2018-11-08 2020-05-14 Lungpacer Medical Inc. Stimulation systems and related user interfaces
US12343535B2 (en) 2019-04-12 2025-07-01 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
US11357979B2 (en) 2019-05-16 2022-06-14 Lungpacer Medical Inc. Systems and methods for sensing and stimulation
US11439829B2 (en) 2019-05-24 2022-09-13 Axonics, Inc. Clinician programmer methods and systems for maintaining target operating temperatures
WO2020242900A1 (en) 2019-05-24 2020-12-03 Axonics Modulation Technologies, Inc. Trainer device for a neurostimulator programmer and associated methods of use with a neurostimulation system
WO2020252037A1 (en) 2019-06-12 2020-12-17 Lungpacer Medical Inc. Circuitry for medical stimulation systems
AU2021207815B2 (en) 2020-01-13 2026-03-26 The Feinstein Institutes For Medical Research Treating bleeding and bleeding disorders via high intensity focused ultrasound stimulation of the spleen
US12551702B2 (en) 2020-02-21 2026-02-17 Boston Scientific Neuromodulation Corporation Selective stimulation of peripheral nerves
US11938324B2 (en) 2020-05-21 2024-03-26 The Feinstein Institutes For Medical Research Systems and methods for vagus nerve stimulation
WO2022077439A1 (zh) * 2020-10-16 2022-04-21 深圳先进技术研究院 穿戴式红外导航超声刺激系统
WO2022236078A1 (en) * 2021-05-07 2022-11-10 Battelle Memorial Institute Distributed device control and wearable system for vagus nerve stimulation
WO2022245878A1 (en) 2021-05-17 2022-11-24 Setpoint Medical Corporation Neurostimulation parameter authentication and expiration system for neurostimulation
WO2023014735A1 (en) 2021-08-03 2023-02-09 Ronald Sahyouni Systems and methods for inducing muscle contraction
US11400299B1 (en) 2021-09-14 2022-08-02 Rainbow Medical Ltd. Flexible antenna for stimulator
US12515046B2 (en) * 2021-10-01 2026-01-06 Washington University Systems and methods for detecting motoneuron excitability
US20250229086A1 (en) 2022-01-20 2025-07-17 Setpoint Medical Corporation Treatment of inflammatory disorders
CN117679639A (zh) * 2023-12-28 2024-03-12 浙江强脑科技有限公司 基于肌电信号刺激迷走神经的方法及装置

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700282A (en) * 1995-10-13 1997-12-23 Zabara; Jacob Heart rhythm stabilization using a neurocybernetic prosthesis
AU3304997A (en) 1996-05-31 1998-01-05 Southern Illinois University Methods of modulating aspects of brain neural plasticity by vagus nerve stimulation
US6341236B1 (en) 1999-04-30 2002-01-22 Ivan Osorio Vagal nerve stimulation techniques for treatment of epileptic seizures
US6466822B1 (en) 2000-04-05 2002-10-15 Neuropace, Inc. Multimodal neurostimulator and process of using it
US6892098B2 (en) * 2001-04-26 2005-05-10 Biocontrol Medical Ltd. Nerve stimulation for treating spasticity, tremor, muscle weakness, and other motor disorders
GB2388966A (en) 2002-05-24 2003-11-26 Cbs Products Ltd Cable blowing machine
US7203548B2 (en) * 2002-06-20 2007-04-10 Advanced Bionics Corporation Cavernous nerve stimulation via unidirectional propagation of action potentials
US7174218B1 (en) * 2003-08-12 2007-02-06 Advanced Bionics Corporation Lead extension system for use with a microstimulator
US20050137645A1 (en) 2003-12-05 2005-06-23 Juha Voipio Novel method for the adjustment of human and animal vagus nerve stimulation
US7805195B2 (en) * 2005-03-24 2010-09-28 Vanderbilt University Respiratory triggered, bilateral laryngeal stimulator to restore normal ventilation in vocal fold paralysis
US8036750B2 (en) * 2005-06-13 2011-10-11 Cardiac Pacemakers, Inc. System for neural control of respiration
US7672728B2 (en) * 2005-12-28 2010-03-02 Cardiac Pacemakers, Inc. Neural stimulator to treat sleep disordered breathing
US8103341B2 (en) * 2006-08-25 2012-01-24 Cardiac Pacemakers, Inc. System for abating neural stimulation side effects
US8050765B2 (en) 2006-08-30 2011-11-01 Cardiac Pacemakers, Inc. Method and apparatus for controlling neural stimulation during disordered breathing
US8121692B2 (en) 2006-08-30 2012-02-21 Cardiac Pacemakers, Inc. Method and apparatus for neural stimulation with respiratory feedback
US7801603B2 (en) * 2006-09-01 2010-09-21 Cardiac Pacemakers, Inc. Method and apparatus for optimizing vagal nerve stimulation using laryngeal activity
US8233982B2 (en) * 2007-02-21 2012-07-31 Cardiac Pacemakers, Inc. Systems and methods for treating supraventricular arrhythmias
JP5189654B2 (ja) * 2007-12-12 2013-04-24 カーディアック ペースメイカーズ, インコーポレイテッド 肺動脈から神経刺激を伝達する刺激システム
CN101939051B (zh) * 2008-02-14 2013-07-10 心脏起搏器公司 用于膈刺激检测的方法和装置
EP2334372A1 (en) 2008-07-08 2011-06-22 Cardiac Pacemakers, Inc. Systems for delivering vagal nerve stimulation
EP2355698B1 (en) * 2008-09-19 2012-12-19 Aalborg Universitet Cardiac related neural activity
US9026206B2 (en) * 2008-10-31 2015-05-05 Medtronic, Inc. Therapy system including cardiac rhythm therapy and neurostimulation capabilities
EP2575961B1 (en) 2010-06-03 2018-08-29 Cardiac Pacemakers, Inc. System for spatially selective vagus nerve stimulation

Also Published As

Publication number Publication date
JP2013530747A (ja) 2013-08-01
EP2575961A1 (en) 2013-04-10
US20110301658A1 (en) 2011-12-08
US8509919B2 (en) 2013-08-13
EP2575961B1 (en) 2018-08-29
US20130310893A1 (en) 2013-11-21
WO2011153024A1 (en) 2011-12-08
US8942824B2 (en) 2015-01-27

Similar Documents

Publication Publication Date Title
JP5769036B2 (ja) 空間選択的迷走神経刺激のためのシステム
JP5776111B2 (ja) 時間的パラメータを使用して神経刺激のターゲットを制御するためのシステム
US11857783B2 (en) Implantable and non-invasive stimulators for gastrointestinal therapeutics
US11752334B2 (en) Method for treating a patient having a pelvic floor dysfunction
US12290681B1 (en) Electrical neurostimulation treatment of overactive bladder
US8594805B2 (en) Systems to detect vagus capture
WO2014164421A1 (en) Systems and methods for treating autonomic instability and medical conditions associated therewith
US20160136432A1 (en) System and method for mapping baroreceptors
US12097365B2 (en) Electrical stimulator for the treatment of back pain and methods of use
WO2012027734A1 (en) System and method for electric diuresis
US20250135201A1 (en) Selective neurostimulation of peripheral nerves with reduced off-target activation
US20250001164A1 (en) Electrical stimulator for the treatment of back pain and methods of use

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140523

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20140523

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20141017

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20141020

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20150120

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20150220

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150319

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20150413

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20150512

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20150526

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20150522

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20150526

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20150610

R150 Certificate of patent or registration of utility model

Ref document number: 5769036

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees