JP5769036B2 - 空間選択的迷走神経刺激のためのシステム - Google Patents

空間選択的迷走神経刺激のためのシステム Download PDF

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Publication number
JP5769036B2
JP5769036B2 JP2013513215A JP2013513215A JP5769036B2 JP 5769036 B2 JP5769036 B2 JP 5769036B2 JP 2013513215 A JP2013513215 A JP 2013513215A JP 2013513215 A JP2013513215 A JP 2013513215A JP 5769036 B2 JP5769036 B2 JP 5769036B2
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JP
Japan
Prior art keywords
stimulation
pulse
electrical stimulation
electrode
vagus nerve
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Expired - Fee Related
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JP2013513215A
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English (en)
Japanese (ja)
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JP2013530747A5 (enExample
JP2013530747A (ja
Inventor
ポール ビー ヨー
ポール ビー ヨー
ウォーレン エム グリル
ウォーレン エム グリル
オルドニェス ファン ガブリエル ヒンカピー
オルドニェス ファン ガブリエル ヒンカピー
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Cardiac Pacemakers Inc
Duke University
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Cardiac Pacemakers Inc
Duke University
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Publication of JP2013530747A publication Critical patent/JP2013530747A/ja
Publication of JP2013530747A5 publication Critical patent/JP2013530747A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114Cardiac control, e.g. by vagal stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128Control systems
    • A61N1/36146Control systems specified by the stimulation parameters
    • A61N1/36167Timing, e.g. stimulation onset
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/388Nerve conduction study, e.g. detecting action potential of peripheral nerves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/389Electromyography [EMG]
    • A61B5/395Details of stimulation, e.g. nerve stimulation to elicit EMG response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4029Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551Spinal or peripheral nerve electrodes
    • A61N1/0556Cuff electrodes

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  • Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Electrotherapy Devices (AREA)
JP2013513215A 2010-06-03 2011-05-24 空間選択的迷走神経刺激のためのシステム Expired - Fee Related JP5769036B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35118110P 2010-06-03 2010-06-03
US61/351,181 2010-06-03
PCT/US2011/037726 WO2011153024A1 (en) 2010-06-03 2011-05-24 System for spatially selective vagus nerve stimulation

Publications (3)

Publication Number Publication Date
JP2013530747A JP2013530747A (ja) 2013-08-01
JP2013530747A5 JP2013530747A5 (enExample) 2014-07-10
JP5769036B2 true JP5769036B2 (ja) 2015-08-26

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Family Applications (1)

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JP2013513215A Expired - Fee Related JP5769036B2 (ja) 2010-06-03 2011-05-24 空間選択的迷走神経刺激のためのシステム

Country Status (4)

Country Link
US (2) US8509919B2 (enExample)
EP (1) EP2575961B1 (enExample)
JP (1) JP5769036B2 (enExample)
WO (1) WO2011153024A1 (enExample)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1909694B1 (en) 2005-07-25 2014-06-11 Rainbow Medical Ltd. Electrical stimulation of blood vessels
DK2107920T3 (da) 2007-01-29 2013-10-21 Univ Fraser Simon Transvaskulært nervestimulationsapparat
EP2185237A1 (en) 2007-09-13 2010-05-19 Cardiac Pacemakers, Inc. Systems for avoiding neural stimulation habituation
US8538535B2 (en) 2010-08-05 2013-09-17 Rainbow Medical Ltd. Enhancing perfusion by contraction
US9005106B2 (en) 2008-01-31 2015-04-14 Enopace Biomedical Ltd Intra-aortic electrical counterpulsation
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
CN102573986B (zh) 2009-06-09 2016-01-20 赛博恩特医疗器械公司 用于无导线刺激器的具有袋部的神经封套
US11051744B2 (en) 2009-11-17 2021-07-06 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
CN102821814B (zh) 2009-12-23 2015-07-15 赛博恩特医疗器械公司 用于治疗慢性炎症的神经刺激设备和系统
US8509919B2 (en) 2010-06-03 2013-08-13 Cardiac Pacemakers, Inc. Spatially selective vagus nerve stimulation
US12172017B2 (en) 2011-05-09 2024-12-24 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
US9980645B1 (en) * 2011-06-21 2018-05-29 Case Western Reserve University High-contact density electrode and fabrication technique for an implantable cuff design
US9526637B2 (en) 2011-09-09 2016-12-27 Enopace Biomedical Ltd. Wireless endovascular stent-based electrodes
AU2013230648B2 (en) 2012-03-05 2017-06-15 Lungpacer Medical Inc. Transvascular nerve stimulation apparatus and methods
US9855431B2 (en) 2012-03-19 2018-01-02 Cardiac Pacemakers, Inc. Systems and methods for monitoring for nerve damage
BR112014032002A2 (pt) 2012-06-21 2017-06-27 Univ Fraser Simon sistemas de estimulação de diafragma transvascular e métodos de utilização
CN108836586B (zh) 2013-11-06 2021-04-06 伊诺佩斯生医有限公司 无线型血管内基于支架的电极
CA2930809A1 (en) 2013-11-22 2015-05-28 Simon Fraser University Apparatus and methods for assisted breathing by transvascular nerve stimulation
EP3824949B1 (en) 2014-01-21 2023-12-20 Lungpacer Medical Inc. Systems for optimization of multi-electrode nerve pacing
US9974597B2 (en) 2014-03-19 2018-05-22 Boston Scientific Scimed, Inc. Systems and methods for assessing and treating tissue
EP2946806B1 (fr) 2014-05-19 2016-07-27 Sorin CRM SAS Dispositif médical implantable actif à optimisation automatique de la configuration d'une sonde de stimulation multi-électrode, notamment d'une sonde de stimulation sélective du nerf vague
US10130809B2 (en) 2014-06-13 2018-11-20 Nervana, LLC Transcutaneous electrostimulator and methods for electric stimulation
US9782584B2 (en) 2014-06-13 2017-10-10 Nervana, LLC Transcutaneous electrostimulator and methods for electric stimulation
US10646715B2 (en) 2014-07-23 2020-05-12 United States Government As Represented By The Department Of Veterans Affairs Parasympathetic activation by vagus nerve stimulation
EP3180072B1 (en) 2014-08-15 2018-11-28 Axonics Modulation Technologies Inc. Electromyographic lead positioning and stimulation titration in a nerve stimulation system for treatment of overactive bladder
WO2016025915A1 (en) 2014-08-15 2016-02-18 Axonics Modulation Technologies, Inc. Integrated electromyographic clinician programmer for use with an implantable neurostimulator
US9855423B2 (en) 2014-08-15 2018-01-02 Axonics Modulation Technologies, Inc. Systems and methods for neurostimulation electrode configurations based on neural localization
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
WO2016182894A1 (en) * 2015-05-08 2016-11-17 Duke University Systems and methods for spinal cord stimulation
EP3405107B1 (en) 2016-01-20 2023-04-12 Setpoint Medical Corporation Control of vagal stimulation
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
US10293164B2 (en) 2017-05-26 2019-05-21 Lungpacer Medical Inc. Apparatus and methods for assisted breathing by transvascular nerve stimulation
US12029901B2 (en) 2017-06-30 2024-07-09 Lungpacer Medical Inc. Devices and methods for prevention, moderation, and/or treatment of cognitive injury
US10195429B1 (en) 2017-08-02 2019-02-05 Lungpacer Medical Inc. Systems and methods for intravascular catheter positioning and/or nerve stimulation
US10940308B2 (en) 2017-08-04 2021-03-09 Lungpacer Medical Inc. Systems and methods for trans-esophageal sympathetic ganglion recruitment
WO2019036470A1 (en) 2017-08-14 2019-02-21 Setpoint Medical Corporation TESTING TEST FOR STIMULATION OF NERVE WAVE
US20190175908A1 (en) 2017-12-11 2019-06-13 Lungpacer Medical Inc. Systems and methods for strengthening a respiratory muscle
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
WO2020097331A1 (en) 2018-11-08 2020-05-14 Lungpacer Medical Inc. Stimulation systems and related user interfaces
AU2020272128B9 (en) 2019-04-12 2025-11-20 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
WO2020232333A1 (en) 2019-05-16 2020-11-19 Lungpacer Medical Inc. Systems and methods for sensing and stimulation
US11848090B2 (en) 2019-05-24 2023-12-19 Axonics, Inc. Trainer for a neurostimulator programmer and associated methods of use with a neurostimulation system
US11439829B2 (en) 2019-05-24 2022-09-13 Axonics, Inc. Clinician programmer methods and systems for maintaining target operating temperatures
EP3983057B1 (en) 2019-06-12 2026-04-08 Lungpacer Medical Inc. Circuitry for medical stimulation systems
JP2023512447A (ja) 2020-01-13 2023-03-27 ザ ファインスタイン インスティチューツ フォー メディカル リサーチ 脾臓への高密度集束超音波刺激による出血及び出血性疾患の治療
US12551702B2 (en) 2020-02-21 2026-02-17 Boston Scientific Neuromodulation Corporation Selective stimulation of peripheral nerves
WO2021236977A1 (en) 2020-05-21 2021-11-25 The Feinstein Institutes For Medical Research Systems and methods for vagus nerve stimulation
WO2022077439A1 (zh) * 2020-10-16 2022-04-21 深圳先进技术研究院 穿戴式红外导航超声刺激系统
US20220355113A1 (en) * 2021-05-07 2022-11-10 Battelle Memorial Institute Distributed device control and wearable system for vagus nerve stimulation
WO2022245878A1 (en) 2021-05-17 2022-11-24 Setpoint Medical Corporation Neurostimulation parameter authentication and expiration system for neurostimulation
EP4380676A4 (en) 2021-08-03 2025-03-19 Ronald Sahyouni SYSTEMS AND METHODS FOR INDUCING MUSCLE CONTRACTION
US11400299B1 (en) 2021-09-14 2022-08-02 Rainbow Medical Ltd. Flexible antenna for stimulator
US12515046B2 (en) * 2021-10-01 2026-01-06 Washington University Systems and methods for detecting motoneuron excitability
US20250229086A1 (en) 2022-01-20 2025-07-17 Setpoint Medical Corporation Treatment of inflammatory disorders
CN117679639A (zh) * 2023-12-28 2024-03-12 浙江强脑科技有限公司 基于肌电信号刺激迷走神经的方法及装置

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700282A (en) * 1995-10-13 1997-12-23 Zabara; Jacob Heart rhythm stabilization using a neurocybernetic prosthesis
AU3304997A (en) 1996-05-31 1998-01-05 Southern Illinois University Methods of modulating aspects of brain neural plasticity by vagus nerve stimulation
US6341236B1 (en) 1999-04-30 2002-01-22 Ivan Osorio Vagal nerve stimulation techniques for treatment of epileptic seizures
US6466822B1 (en) 2000-04-05 2002-10-15 Neuropace, Inc. Multimodal neurostimulator and process of using it
US6892098B2 (en) * 2001-04-26 2005-05-10 Biocontrol Medical Ltd. Nerve stimulation for treating spasticity, tremor, muscle weakness, and other motor disorders
GB2388966A (en) 2002-05-24 2003-11-26 Cbs Products Ltd Cable blowing machine
US7203548B2 (en) * 2002-06-20 2007-04-10 Advanced Bionics Corporation Cavernous nerve stimulation via unidirectional propagation of action potentials
US7174218B1 (en) * 2003-08-12 2007-02-06 Advanced Bionics Corporation Lead extension system for use with a microstimulator
US20050137645A1 (en) 2003-12-05 2005-06-23 Juha Voipio Novel method for the adjustment of human and animal vagus nerve stimulation
WO2006102591A2 (en) 2005-03-24 2006-09-28 Vanderbilt University Respiratory triggered, bilateral laryngeal stimulator to restore normal ventilation in vocal fold paralysis
US8036750B2 (en) * 2005-06-13 2011-10-11 Cardiac Pacemakers, Inc. System for neural control of respiration
US7672728B2 (en) * 2005-12-28 2010-03-02 Cardiac Pacemakers, Inc. Neural stimulator to treat sleep disordered breathing
US8103341B2 (en) * 2006-08-25 2012-01-24 Cardiac Pacemakers, Inc. System for abating neural stimulation side effects
US8121692B2 (en) 2006-08-30 2012-02-21 Cardiac Pacemakers, Inc. Method and apparatus for neural stimulation with respiratory feedback
US8050765B2 (en) 2006-08-30 2011-11-01 Cardiac Pacemakers, Inc. Method and apparatus for controlling neural stimulation during disordered breathing
US7801603B2 (en) * 2006-09-01 2010-09-21 Cardiac Pacemakers, Inc. Method and apparatus for optimizing vagal nerve stimulation using laryngeal activity
US8233982B2 (en) * 2007-02-21 2012-07-31 Cardiac Pacemakers, Inc. Systems and methods for treating supraventricular arrhythmias
WO2009075750A2 (en) * 2007-12-12 2009-06-18 Cardiac Pacemakers, Inc. System for delivering neurostimulation from pulmonary artery
CN101939051B (zh) * 2008-02-14 2013-07-10 心脏起搏器公司 用于膈刺激检测的方法和装置
JP5427233B2 (ja) 2008-07-08 2014-02-26 カーディアック ペースメイカーズ, インコーポレイテッド 迷走神経刺激を送達する医療システム
WO2010031406A1 (en) 2008-09-19 2010-03-25 Aalborg Universitet Cardiac related neural activity
WO2010051500A1 (en) 2008-10-31 2010-05-06 Medtronic, Inc. Therapy system including cardiac rhythm therapy and neurostimulation capabilities
US8509919B2 (en) 2010-06-03 2013-08-13 Cardiac Pacemakers, Inc. Spatially selective vagus nerve stimulation

Also Published As

Publication number Publication date
US20130310893A1 (en) 2013-11-21
WO2011153024A1 (en) 2011-12-08
US8509919B2 (en) 2013-08-13
EP2575961B1 (en) 2018-08-29
US8942824B2 (en) 2015-01-27
US20110301658A1 (en) 2011-12-08
EP2575961A1 (en) 2013-04-10
JP2013530747A (ja) 2013-08-01

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