JP5763631B2 - Ｍｐｉ誘導による薬物送達のための刺激応答性キャリア - Google Patents

Ｍｐｉ誘導による薬物送達のための刺激応答性キャリア Download PDF

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JP5763631B2
JP5763631B2 JP2012518140A JP2012518140A JP5763631B2 JP 5763631 B2 JP5763631 B2 JP 5763631B2 JP 2012518140 A JP2012518140 A JP 2012518140A JP 2012518140 A JP2012518140 A JP 2012518140A JP 5763631 B2 JP5763631 B2 JP 5763631B2
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shell structure
composition
drug
contrast agent
magnetic
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JP2012532120A (ja
JP2012532120A5 (enExample
Inventor
ダーク ブルディンスキ
ダーク ブルディンスキ
ジェロエン アー ピッケマート
ジェロエン アー ピッケマート
バートランド シュミット
バートランド シュミット
ホルガー グルエル
ホルガー グルエル
サンダー ランゲレイス
サンダー ランゲレイス
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Koninklijke Philips NV
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Koninklijke Philips NV
Koninklijke Philips Electronics NV
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2012518140A 2009-07-01 2010-06-25 Ｍｐｉ誘導による薬物送達のための刺激応答性キャリア Expired - Fee Related JP5763631B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09164301 2009-07-01
EP09164301.5 2009-07-01
PCT/IB2010/052918 WO2011001351A1 (en) 2009-07-01 2010-06-25 Stimuli-responsive carriers for mpi-guided drug delivery

Publications (3)

Publication Number Publication Date
JP2012532120A JP2012532120A (ja) 2012-12-13
JP2012532120A5 JP2012532120A5 (enExample) 2013-08-08
JP5763631B2 true JP5763631B2 (ja) 2015-08-12

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US (1) US20120100079A1 (enExample)
EP (1) EP2448557A1 (enExample)
JP (1) JP5763631B2 (enExample)
CN (1) CN102470098A (enExample)
RU (1) RU2561035C2 (enExample)
WO (1) WO2011001351A1 (enExample)

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US9393198B2 (en) 2010-03-22 2016-07-19 Signpath Pharma Inc. Intravenous curcumin and derivatives for treatment of neurodegenerative and stress disorders
EP2714011B1 (en) * 2011-06-03 2018-01-31 Signpath Pharma Inc. Liposomal mitigation of drug-induced long qt syndrome and potassium delayed-rectifier current
US10117881B2 (en) 2011-06-03 2018-11-06 Signpath Pharma, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, LYSOPG and LYSOPC against drugs that cause channelopathies
US10238602B2 (en) 2011-06-03 2019-03-26 Signpath Pharma, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, LysoPG and LysoPC against drugs that cause channelopathies
US12004868B2 (en) 2011-06-03 2024-06-11 Signpath Pharma Inc. Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel
US10449193B2 (en) 2011-06-03 2019-10-22 Signpath Pharma Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, lysoPG and lysoPC against drugs that cause channelopathies
US10349884B2 (en) 2011-06-03 2019-07-16 Sighpath Pharma Inc. Liposomal mitigation of drug-induced inhibition of the cardiac ikr channel
WO2012169973A1 (en) * 2011-06-09 2012-12-13 Agency For Science, Technology And Research A core-shell nanoparticle
ITRM20120169A1 (it) 2012-04-19 2013-10-20 Consiglio Nazionale Ricerche Dispositivo di rilascio di specie chimiche a controllo ottico
CA2882978A1 (en) 2012-08-31 2014-03-06 University Of North Texas Health Science Center Curcumin-er, a liposomal-plga sustained release nanocurcumin for minimizing qt prolongation for cancer therapy
WO2014090313A1 (en) * 2012-12-13 2014-06-19 Universitaet Ulm Nanoparticle with a molecularly imprinted coating
JP2016509032A (ja) * 2013-02-20 2016-03-24 トパス ゲーエムベーハー Ｍｐｉを用いた消化管の診断検査用経口造影剤
CN103357027B (zh) * 2013-08-01 2016-02-10 孙博 一种具有mri示踪效应的纳米微囊
KR20150026613A (ko) * 2013-09-03 2015-03-11 삼성전자주식회사 소수성 물질 및 조영제를 포함하는 리포좀 및 그의 용도
JP6895252B2 (ja) 2013-12-18 2021-06-30 サインパス ファルマ, インク.Signpath Pharma, Inc. 心筋ｉｋｒチャネルの薬剤誘発性阻害のリポソームによる軽減
GB201509934D0 (en) * 2015-06-08 2015-07-22 King S College London Nanoparticles
AU2017257496B2 (en) 2016-04-27 2020-05-07 Signpath Pharma, Inc. Prevention of drug-induced atrio-ventricular block
US10775452B2 (en) 2016-07-12 2020-09-15 Magnetic Insight, Inc. Magnetic particle imaging
IL268600B2 (en) * 2017-03-03 2025-09-01 Baxalta Inc Methods for determining potency of adeno-associated virus preparations
KR102024273B1 (ko) 2017-03-27 2019-11-04 주식회사 피에프디 약물 작용 관리 장치 및 방법
US11045552B2 (en) 2017-04-04 2021-06-29 International Business Machines Corporation Stimulus-responsive micellar carrier
CN107320738B (zh) * 2017-07-12 2020-06-12 福州大学 一种四氧化三锰-乳白蛋白纳米球及其制备与应用
JP6934833B2 (ja) 2018-03-30 2021-09-15 三菱パワー株式会社 水質モニタリングシステムとそれを備えた蒸気タービンシステム、並びに水質モニタリング方法
WO2020186185A1 (en) 2019-03-13 2020-09-17 Magnetic Insight, Inc. Magnetic particle actuation
CN112043682B (zh) * 2020-09-19 2022-03-11 新乡医学院 一种基于多孔钆掺杂氧化铁纳米簇的磁性纳米药物载体及其制备方法
US11839458B2 (en) 2021-02-08 2023-12-12 Vanberbilt University Magnetic particle imaging using an ultrasonic driving field

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US5534499A (en) 1994-05-19 1996-07-09 The University Of British Columbia Lipophilic drug derivatives for use in liposomes
US6726925B1 (en) 1998-06-18 2004-04-27 Duke University Temperature-sensitive liposomal formulation
US6835394B1 (en) 1999-12-14 2004-12-28 The Trustees Of The University Of Pennsylvania Polymersomes and related encapsulating membranes
AU2003272341A1 (en) * 2002-09-11 2004-04-30 Duke University Methods and compositions for blood pool identification, drug distribution quantification and drug release verification
EP1718282A4 (en) * 2004-01-15 2010-07-14 Sinai School Medicine PROCESS AND COMPOSITIONS FOR IMAGE PRESENTATION
WO2005077330A1 (en) * 2004-02-17 2005-08-25 The University Of Melbourne Electromagnetic radiation addressable materials
EP1738773A1 (de) * 2005-06-29 2007-01-03 Schering AG Magnetische Eisenoxidpartikel enthaltende Zusammensetzung und deren Vervendung in bildgebenden Verfahren
TWI314465B (en) * 2005-12-30 2009-09-11 Ind Tech Res Inst Thermosensitive nanostructure for hyperthermia treatment
CZ301067B6 (cs) * 2006-02-24 2009-10-29 Ústav makromolekulární chemie AV CR Superparamagnetické nanocástice na bázi oxidu železa s modifikovaným povrchem, zpusob jejich prípravy a použití
KR20080035926A (ko) * 2006-10-20 2008-04-24 재단법인서울대학교산학협력재단 자성체 나노입자를 함유한 코어-외각 구조의 금 나노입자의자기공명영상의 티2 조영제, 암 진단제 및 암치료제로서의 용도
EP2112957A1 (en) * 2007-02-16 2009-11-04 Koninklijke Philips Electronics N.V. Method and separator system for separating magnetic particles, separator column for use in a separator system
JP2009051752A (ja) * 2007-08-24 2009-03-12 Hitachi Ltd 磁性粒子含有薬剤キャリア及びそれを用いた治療装置
WO2009126441A1 (en) * 2008-04-10 2009-10-15 Board Of Regents, The University Of Texas System Compositions and methods for thermo-sensitive nanoparticles and magnetic nanoparticles
TWI374761B (en) * 2008-05-13 2012-10-21 Univ Nat Chiao Tung Method for forming a drug container having the magnetic nano single-crystalline capsule

Also Published As

Publication number Publication date
JP2012532120A (ja) 2012-12-13
WO2011001351A1 (en) 2011-01-06
RU2561035C2 (ru) 2015-08-20
RU2012103347A (ru) 2013-08-10
US20120100079A1 (en) 2012-04-26
CN102470098A (zh) 2012-05-23
EP2448557A1 (en) 2012-05-09

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