JP5762282B2 - 変形性関節症に関連する状態に対する遺伝的素因の検出 - Google Patents

変形性関節症に関連する状態に対する遺伝的素因の検出 Download PDF

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JP5762282B2
JP5762282B2 JP2011507714A JP2011507714A JP5762282B2 JP 5762282 B2 JP5762282 B2 JP 5762282B2 JP 2011507714 A JP2011507714 A JP 2011507714A JP 2011507714 A JP2011507714 A JP 2011507714A JP 5762282 B2 JP5762282 B2 JP 5762282B2
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osteoarthritis
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genotype
il1rn
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JP2011520433A5 (OSRAM
JP2011520433A (ja
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ジャック エフ． ブコウスキー，
ジャック エフ． ブコウスキー，
ナズニーン アジズ，
ナズニーン アジズ，
ファ−イン ワン，
ファ−イン ワン，
ケネス ハットナー，
ケネス ハットナー，
ムクンダン アッター
ムクンダン アッター
スティーブン ビー アブラムソン
スティーブン ビー アブラムソン
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インタールーキン ジェネティクス， インコーポレイテッド
インタールーキン ジェネティクス， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2011507714A 2008-05-02 2009-05-04 変形性関節症に関連する状態に対する遺伝的素因の検出 Active JP5762282B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4999208P 2008-05-02 2008-05-02
US61/049,992 2008-05-02
US11874408P 2008-12-01 2008-12-01
US61/118,744 2008-12-01
PCT/US2009/042746 WO2009135218A2 (en) 2008-05-02 2009-05-04 Detecting genetic predisposition to osteoarthritis associated conditions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015116397A Division JP6263499B2 (ja) 2008-05-02 2015-06-09 変形性関節症に関連する状態に対する遺伝的素因の検出

Publications (3)

Publication Number Publication Date
JP2011520433A JP2011520433A (ja) 2011-07-21
JP2011520433A5 JP2011520433A5 (OSRAM) 2013-04-18
JP5762282B2 true JP5762282B2 (ja) 2015-08-12

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JP2011507714A Active JP5762282B2 (ja) 2008-05-02 2009-05-04 変形性関節症に関連する状態に対する遺伝的素因の検出
JP2015116397A Active JP6263499B2 (ja) 2008-05-02 2015-06-09 変形性関節症に関連する状態に対する遺伝的素因の検出
JP2017241315A Withdrawn JP2018038436A (ja) 2008-05-02 2017-12-18 変形性関節症に関連する状態に対する遺伝的素因の検出

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JP2015116397A Active JP6263499B2 (ja) 2008-05-02 2015-06-09 変形性関節症に関連する状態に対する遺伝的素因の検出
JP2017241315A Withdrawn JP2018038436A (ja) 2008-05-02 2017-12-18 変形性関節症に関連する状態に対する遺伝的素因の検出

Country Status (9)

Country Link
US (2) US20100098775A1 (OSRAM)
EP (3) EP3467126A1 (OSRAM)
JP (3) JP5762282B2 (OSRAM)
AU (1) AU2009242490B2 (OSRAM)
CA (1) CA2723239C (OSRAM)
DK (2) DK2283156T3 (OSRAM)
ES (2) ES2708826T3 (OSRAM)
NZ (1) NZ589034A (OSRAM)
WO (1) WO2009135218A2 (OSRAM)

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US20100098775A1 (en) * 2008-05-02 2010-04-22 Interleukin Genetics, Inc. Detecting genetic predisposition to osteoarthritis associated conditions
US20120115137A1 (en) * 2010-08-31 2012-05-10 Kornman Kenneth S Methods of Predicting Osteoarthritis
WO2014023704A1 (en) * 2012-08-06 2014-02-13 xARES TRADING S.A. Prognosis biomarkers in cartilage disorders
US10221456B2 (en) * 2012-08-06 2019-03-05 Merck Patent Gmbh Genetic markers for predicting responsiveness to FPG-18 compound
WO2017123696A1 (en) 2016-01-12 2017-07-20 Interleukin Genetics, Inc. Methods for predicting response to treatment
US10337070B2 (en) 2017-01-12 2019-07-02 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
CN111163791A (zh) 2017-09-29 2020-05-15 默克专利有限公司 预测对fgf-18化合物反应性的代谢生物标志物
CN111164429B (zh) 2017-09-29 2024-08-09 默克专利有限公司 预测对fgf-18化合物反应性的炎性生物标志物
HRP20240665T1 (hr) * 2018-09-10 2024-08-16 Merck Patent Gmbh Markeri korisni u strategijama obogaćivanja za liječenje osteoartritisa
WO2020112853A1 (en) 2018-11-28 2020-06-04 Genascence Corporation Methods and compositions for treating osteoarthritis
CA3142662A1 (en) 2019-06-06 2020-12-10 Sitokine Limited Compositions and methods for treating lung, colorectal and breast cancer
EP4007819A4 (en) * 2019-08-02 2023-08-09 New York University METHODS AND COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS
WO2021028469A1 (en) 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
WO2021205013A1 (en) 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19

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US4998617A (en) 1986-09-15 1991-03-12 Laura Lupton Inc Facial cosmetic liquid make up kit
US4968607A (en) 1987-11-25 1990-11-06 Immunex Corporation Interleukin-1 receptors
US5459039A (en) 1989-05-12 1995-10-17 Duke University Methods for mapping genetic mutations
FR2650840B1 (fr) 1989-08-11 1991-11-29 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
US6004744A (en) 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
DE69433811T2 (de) 1993-01-07 2005-06-23 Sequenom, Inc., San Diego Dns - sequenzierung durch massenspektronomie
US5593826A (en) * 1993-03-22 1997-01-14 Perkin-Elmer Corporation, Applied Biosystems, Inc. Enzymatic ligation of 3'amino-substituted oligonucleotides
US5686246A (en) * 1995-08-03 1997-11-11 Kornman; Kenneth S. Detecting genetic predisposition to periodontal disease
US5942390A (en) 1996-01-12 1999-08-24 Cedars-Sinai Medical Center Method of diagnosing predisposition for ulcerative colitis in Jewish population by detection of interleukin-1 receptor antagonist polymorphism
US5698399A (en) * 1996-04-05 1997-12-16 Duff; Gordon W. Detecting genetic predisposition for osteoporosis
GB9621129D0 (en) * 1996-10-10 1996-11-27 Duff Gordon W Detecting genetic predisposition to sight-threatening diabetic retinopathy
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GB9711040D0 (en) * 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
TWI346700B (en) * 2002-01-25 2011-08-11 Interleukin Genetics Inc The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes
JP5649263B2 (ja) * 2003-11-26 2015-01-07 セレラ コーポレーション 心臓血管障害および薬物応答に関連した遺伝子多型、それらの検出方法および用途
EP1951910A4 (en) * 2005-11-30 2010-02-03 Univ North Carolina IDENTIFICATION OF SOMATOSENSORY SUFFERED ASSOCIATED GENETIC POLYMORPHIC VARIANTS AND METHOD OF USE THEREOF
US20100098775A1 (en) * 2008-05-02 2010-04-22 Interleukin Genetics, Inc. Detecting genetic predisposition to osteoarthritis associated conditions
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Also Published As

Publication number Publication date
AU2009242490B2 (en) 2015-01-22
ES2708826T3 (es) 2019-04-11
EP2283156A2 (en) 2011-02-16
AU2009242490A1 (en) 2009-11-05
DK2283156T3 (en) 2016-02-15
NZ589034A (en) 2012-10-26
US20100098775A1 (en) 2010-04-22
ES2561316T3 (es) 2016-02-25
EP2283156B1 (en) 2015-11-11
JP6263499B2 (ja) 2018-01-17
JP2018038436A (ja) 2018-03-15
EP3467126A1 (en) 2019-04-10
CA2723239C (en) 2020-07-21
US20160340734A1 (en) 2016-11-24
EP3059323A1 (en) 2016-08-24
WO2009135218A3 (en) 2010-04-01
CA2723239A1 (en) 2009-11-05
WO2009135218A2 (en) 2009-11-05
EP3059323B1 (en) 2018-12-12
JP2015211677A (ja) 2015-11-26
DK3059323T3 (en) 2019-03-04
JP2011520433A (ja) 2011-07-21

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