JP5758904B2 - ニトライトの医薬製剤及びそれらの使用 - Google Patents

ニトライトの医薬製剤及びそれらの使用 Download PDF

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Publication number
JP5758904B2
JP5758904B2 JP2012534359A JP2012534359A JP5758904B2 JP 5758904 B2 JP5758904 B2 JP 5758904B2 JP 2012534359 A JP2012534359 A JP 2012534359A JP 2012534359 A JP2012534359 A JP 2012534359A JP 5758904 B2 JP5758904 B2 JP 5758904B2
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Prior art keywords
nitrite
pharmaceutical composition
composition according
pharmaceutically acceptable
formulation
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Expired - Fee Related
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JP2012534359A
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Japanese (ja)
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JP2013508289A5 (https=
JP2013508289A (ja
Inventor
ケビル，クリストファー
ジョルダーノ，アンソニー
フラナガン，ダグラス，アール．
コンスタンティニデス，パナイオティス，ピー．
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セラバスク インコーポレーテッド
セラバスク インコーポレーテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012534359A 2009-10-14 2010-10-14 ニトライトの医薬製剤及びそれらの使用 Expired - Fee Related JP5758904B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25148309P 2009-10-14 2009-10-14
US61/251,483 2009-10-14
PCT/US2010/052683 WO2011047161A1 (en) 2009-10-14 2010-10-14 Pharmaceutical formulations of nitrite and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015113882A Division JP6125567B2 (ja) 2009-10-14 2015-06-04 ニトライトの医薬製剤及びそれらの使用

Publications (3)

Publication Number Publication Date
JP2013508289A JP2013508289A (ja) 2013-03-07
JP2013508289A5 JP2013508289A5 (https=) 2013-10-31
JP5758904B2 true JP5758904B2 (ja) 2015-08-05

Family

ID=43855036

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2012534359A Expired - Fee Related JP5758904B2 (ja) 2009-10-14 2010-10-14 ニトライトの医薬製剤及びそれらの使用
JP2015113882A Expired - Fee Related JP6125567B2 (ja) 2009-10-14 2015-06-04 ニトライトの医薬製剤及びそれらの使用
JP2017074888A Pending JP2017141275A (ja) 2009-10-14 2017-04-05 ニトライトの医薬製剤及びそれらの使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015113882A Expired - Fee Related JP6125567B2 (ja) 2009-10-14 2015-06-04 ニトライトの医薬製剤及びそれらの使用
JP2017074888A Pending JP2017141275A (ja) 2009-10-14 2017-04-05 ニトライトの医薬製剤及びそれらの使用

Country Status (10)

Country Link
US (4) US10463689B2 (https=)
EP (1) EP2488035B1 (https=)
JP (3) JP5758904B2 (https=)
CN (2) CN107260756A (https=)
AU (1) AU2010306755B2 (https=)
CA (1) CA2777066C (https=)
ES (1) ES2633618T3 (https=)
IL (1) IL219155A0 (https=)
IN (1) IN2012DN03428A (https=)
WO (1) WO2011047161A1 (https=)

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US8627204B2 (en) * 2011-10-18 2014-01-07 Microsoft Corporation Custom optimization of web pages
WO2014130691A2 (en) 2013-02-20 2014-08-28 Theravasc Inc. Pharmaceutical formulations of nitrite and uses thereof
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US20170349438A1 (en) 2016-06-06 2017-12-07 Theravasc Inc. Pharmaceutical formulations of nitrite and uses thereof
WO2018152509A1 (en) * 2017-02-20 2018-08-23 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Hydrogen sulfide and/or nitrite in the treatment and prevention of atrial fibrillation
US11850271B1 (en) * 2023-05-16 2023-12-26 King Faisal University Topical skin cream
WO2026006722A1 (en) 2024-06-28 2026-01-02 The Regents Of The University Of Michigan Nitric oxide generating medical devices and methods

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Also Published As

Publication number Publication date
US20200085861A1 (en) 2020-03-19
WO2011047161A1 (en) 2011-04-21
EP2488035A4 (en) 2013-07-31
JP2015180674A (ja) 2015-10-15
EP2488035A1 (en) 2012-08-22
CN107260756A (zh) 2017-10-20
AU2010306755B2 (en) 2015-12-24
US10307441B2 (en) 2019-06-04
ES2633618T3 (es) 2017-09-22
US10463689B2 (en) 2019-11-05
CA2777066A1 (en) 2011-04-21
IN2012DN03428A (https=) 2015-10-23
EP2488035B1 (en) 2017-04-26
US20160067279A1 (en) 2016-03-10
CA2777066C (en) 2020-02-18
US20110086069A1 (en) 2011-04-14
AU2010306755A1 (en) 2012-05-03
JP2017141275A (ja) 2017-08-17
IL219155A0 (en) 2012-06-28
JP6125567B2 (ja) 2017-05-10
JP2013508289A (ja) 2013-03-07
US20200297756A1 (en) 2020-09-24
CN102686111A (zh) 2012-09-19

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