JP5728717B2 - Foxm1ペプチドおよびそれを含むワクチン - Google Patents

Foxm1ペプチドおよびそれを含むワクチン Download PDF

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JP5728717B2
JP5728717B2 JP2011535341A JP2011535341A JP5728717B2 JP 5728717 B2 JP5728717 B2 JP 5728717B2 JP 2011535341 A JP2011535341 A JP 2011535341A JP 2011535341 A JP2011535341 A JP 2011535341A JP 5728717 B2 JP5728717 B2 JP 5728717B2
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peptide
seq
cancer
amino acid
foxm1
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Japanese (ja)
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JP2012517799A (ja
JP2012517799A5 (enExample
Inventor
卓也 角田
卓也 角田
龍司 大沢
龍司 大沢
祥子 吉村
祥子 吉村
朝久 渡辺
朝久 渡辺
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Oncotherapy Science Inc
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Oncotherapy Science Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4242Transcription factors, e.g. SOX or c-MYC
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2011535341A 2009-02-18 2010-02-17 Foxm1ペプチドおよびそれを含むワクチン Active JP5728717B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15340809P 2009-02-18 2009-02-18
US61/153,408 2009-02-18
PCT/JP2010/001005 WO2010095428A1 (en) 2009-02-18 2010-02-17 Foxm1 peptides and vaccines containing the same

Publications (3)

Publication Number Publication Date
JP2012517799A JP2012517799A (ja) 2012-08-09
JP2012517799A5 JP2012517799A5 (enExample) 2013-03-28
JP5728717B2 true JP5728717B2 (ja) 2015-06-03

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JP2011535341A Active JP5728717B2 (ja) 2009-02-18 2010-02-17 Foxm1ペプチドおよびそれを含むワクチン

Country Status (15)

Country Link
US (1) US8617562B2 (enExample)
EP (1) EP2408912B1 (enExample)
JP (1) JP5728717B2 (enExample)
KR (1) KR101713586B1 (enExample)
CN (1) CN102405285B (enExample)
BR (1) BRPI1008887A2 (enExample)
CA (1) CA2752560C (enExample)
DK (1) DK2408912T3 (enExample)
ES (1) ES2618896T3 (enExample)
IL (1) IL214435A0 (enExample)
MX (1) MX2011008763A (enExample)
RU (1) RU2560431C2 (enExample)
SG (1) SG173751A1 (enExample)
TW (1) TWI469791B (enExample)
WO (1) WO2010095428A1 (enExample)

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EP4032899A1 (en) 2007-08-20 2022-07-27 Oncotherapy Science, Inc. Foxm1 peptide and medicinal agent comprising the same
JP6159996B2 (ja) * 2012-03-09 2017-07-12 株式会社富士薬品 ペプチドを含む医薬組成物
GB201410686D0 (en) * 2014-06-16 2014-07-30 Immunocore Ltd & Adaptimmune Ltd Peptides
BR112018005581A2 (pt) * 2015-10-08 2018-10-16 Oncotherapy Science, Inc. peptídeo derivado de foxm1 e vacina incluindo o mesmo
CN105524159B (zh) * 2015-11-16 2021-04-09 西南交通大学 具有癌细胞选择性杀伤和迁移抑制作用的多肽分子与用途
CN105999227B (zh) * 2016-08-12 2019-08-06 湖南大学 FOXM1蛋白氮端(1-234 aa)的表达及其用途
CA3039541A1 (en) 2016-10-07 2018-04-12 Board Of Regents,The University Of Texas System Hla-restricted vgll1 peptides and use thereof
CN111787930B (zh) * 2017-10-06 2024-12-20 芝加哥大学 针对癌症特异性抗原对t淋巴细胞的筛选
ES2935702T3 (es) * 2018-04-11 2023-03-09 Enterome S A Péptidos antigénicos para la prevención y el tratamiento del cáncer
CN109055327B (zh) * 2018-07-23 2021-04-06 浙江工业大学 醛酮还原酶突变体及其应用
TW202023581A (zh) 2018-08-02 2020-07-01 日商腫瘤療法 科學股份有限公司 來自cdca1的胜肽及含有此的疫苗
CN114591400B (zh) * 2022-03-29 2022-10-21 西南交通大学 一组靶向FoxM1-DBD多肽及其应用

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US5679647A (en) 1993-08-26 1997-10-21 The Regents Of The University Of California Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
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Also Published As

Publication number Publication date
EP2408912B1 (en) 2017-01-18
EP2408912A1 (en) 2012-01-25
US8617562B2 (en) 2013-12-31
BRPI1008887A2 (pt) 2016-03-01
WO2010095428A1 (en) 2010-08-26
TWI469791B (zh) 2015-01-21
EP2408912A4 (en) 2013-04-17
IL214435A0 (en) 2011-09-27
KR20110117241A (ko) 2011-10-26
MX2011008763A (es) 2011-09-09
TW201032821A (en) 2010-09-16
RU2560431C2 (ru) 2015-08-20
SG173751A1 (en) 2011-09-29
RU2011138160A (ru) 2013-03-27
CA2752560A1 (en) 2010-08-26
ES2618896T3 (es) 2017-06-22
CN102405285A (zh) 2012-04-04
CA2752560C (en) 2017-01-24
KR101713586B1 (ko) 2017-03-08
AU2010216980A1 (en) 2011-08-25
CN102405285B (zh) 2015-04-22
US20120156231A1 (en) 2012-06-21
DK2408912T3 (en) 2017-03-20
JP2012517799A (ja) 2012-08-09

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