JP5715605B2 - Ｎ−アシル環状アミン誘導体またはその医薬上許容される塩からなる医薬 - Google Patents
Ｎ−アシル環状アミン誘導体またはその医薬上許容される塩からなる医薬 Download PDFInfo
- Publication number
- JP5715605B2 JP5715605B2 JP2012202153A JP2012202153A JP5715605B2 JP 5715605 B2 JP5715605 B2 JP 5715605B2 JP 2012202153 A JP2012202153 A JP 2012202153A JP 2012202153 A JP2012202153 A JP 2012202153A JP 5715605 B2 JP5715605 B2 JP 5715605B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- optionally substituted
- substituted
- saturated heterocyclic
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 CC(CCC1)CC*1NC Chemical compound CC(CCC1)CC*1NC 0.000 description 5
- HJNTWRBRIHMCRG-UHFFFAOYSA-N C(CN(CC1)CCC1c1c[nH]c2c1cccc2)C1NCCC1 Chemical compound C(CN(CC1)CCC1c1c[nH]c2c1cccc2)C1NCCC1 HJNTWRBRIHMCRG-UHFFFAOYSA-N 0.000 description 1
- OXBPNQAZPUKLTF-KRWDZBQOSA-N C(CN(CC1)CCC1c1c[nH]c2c1cccc2)[C@H]1NCCCC1 Chemical compound C(CN(CC1)CCC1c1c[nH]c2c1cccc2)[C@H]1NCCCC1 OXBPNQAZPUKLTF-KRWDZBQOSA-N 0.000 description 1
- QTIKWXQBUWGSCP-FCHUYYIVSA-N CC(C)(C)OC(N(C1)[C@H](CC(N(CC2)CCC2c2c[n](C(OC(C)(C)C)=O)c3c2cccc3)=O)C[C@H]1OC)=O Chemical compound CC(C)(C)OC(N(C1)[C@H](CC(N(CC2)CCC2c2c[n](C(OC(C)(C)C)=O)c3c2cccc3)=O)C[C@H]1OC)=O QTIKWXQBUWGSCP-FCHUYYIVSA-N 0.000 description 1
- ISQYKHGGGYDEKA-SECBINFHSA-N CC(C)(C)OC(N1[C@H](CCO)COCC1)=O Chemical compound CC(C)(C)OC(N1[C@H](CCO)COCC1)=O ISQYKHGGGYDEKA-SECBINFHSA-N 0.000 description 1
- UTHWIOICGCUXQD-SANMLTNESA-N CC(C)c1cc([nH]c(C(N2[C@H](CCN(CC3)CCC3C(c(cc3)ccc3F)=O)CCC2)=O)c2)c2cc1 Chemical compound CC(C)c1cc([nH]c(C(N2[C@H](CCN(CC3)CCC3C(c(cc3)ccc3F)=O)CCC2)=O)c2)c2cc1 UTHWIOICGCUXQD-SANMLTNESA-N 0.000 description 1
- QJFGPBJMAWBKKA-UHFFFAOYSA-O CC(c1ccccc1N)=[NH2+] Chemical compound CC(c1ccccc1N)=[NH2+] QJFGPBJMAWBKKA-UHFFFAOYSA-O 0.000 description 1
- BFQARNDIMKOOQQ-UHFFFAOYSA-N CC1c2ccccc2NC1 Chemical compound CC1c2ccccc2NC1 BFQARNDIMKOOQQ-UHFFFAOYSA-N 0.000 description 1
- XYNJJGBBTYTHJE-ZDUSSCGKSA-N CCOC([C@H](CCC(c1cccnc1)=O)NC(OC(C)(C)C)=O)=O Chemical compound CCOC([C@H](CCC(c1cccnc1)=O)NC(OC(C)(C)C)=O)=O XYNJJGBBTYTHJE-ZDUSSCGKSA-N 0.000 description 1
- WAJGLXUGRSSHLA-LUVFDKCISA-N CCOCCO[C@H](C[C@H]1CC(N(CC2)CCC2C(C2)c(cccc3)c3N2C(OC(C)(C)C)=O)O)CN1C(OC(C)(C)C)=O Chemical compound CCOCCO[C@H](C[C@H]1CC(N(CC2)CCC2C(C2)c(cccc3)c3N2C(OC(C)(C)C)=O)O)CN1C(OC(C)(C)C)=O WAJGLXUGRSSHLA-LUVFDKCISA-N 0.000 description 1
- YXZDEYTVUWBBOJ-WOJBJXKFSA-N CCOCCO[C@H]1CN[C@H](CCN(CC2)CCC2c2c[nH]c3c2cccc3)C1 Chemical compound CCOCCO[C@H]1CN[C@H](CCN(CC2)CCC2c2c[nH]c3c2cccc3)C1 YXZDEYTVUWBBOJ-WOJBJXKFSA-N 0.000 description 1
- QYEMNJMSULGQRD-UHFFFAOYSA-N CN(c1ccccc1C=C1)C1=O Chemical compound CN(c1ccccc1C=C1)C1=O QYEMNJMSULGQRD-UHFFFAOYSA-N 0.000 description 1
- RSQUAQMIGSMNNE-UHFFFAOYSA-N CN1c2ccccc2CC1=O Chemical compound CN1c2ccccc2CC1=O RSQUAQMIGSMNNE-UHFFFAOYSA-N 0.000 description 1
- GRDNENMVSPDQBD-UHFFFAOYSA-N CN1c2ccccc2CCC1=O Chemical compound CN1c2ccccc2CCC1=O GRDNENMVSPDQBD-UHFFFAOYSA-N 0.000 description 1
- ZRXHLJNBNWVNIM-UHFFFAOYSA-N Cc1c[o]c2ccccc12 Chemical compound Cc1c[o]c2ccccc12 ZRXHLJNBNWVNIM-UHFFFAOYSA-N 0.000 description 1
- GAUKCDPSYQUYQL-UHFFFAOYSA-N Cc1n[o]c2ccccc12 Chemical compound Cc1n[o]c2ccccc12 GAUKCDPSYQUYQL-UHFFFAOYSA-N 0.000 description 1
- DAEGDNYLKMKZRG-UHFFFAOYSA-N Cc1n[s]c2ccccc12 Chemical compound Cc1n[s]c2ccccc12 DAEGDNYLKMKZRG-UHFFFAOYSA-N 0.000 description 1
- GKYQNIKCDAVPKL-HNNXBMFYSA-N Fc(cc1)cc2c1c(C1CCN(CC[C@H]3NCCC3)CC1)n[nH]2 Chemical compound Fc(cc1)cc2c1c(C1CCN(CC[C@H]3NCCC3)CC1)n[nH]2 GKYQNIKCDAVPKL-HNNXBMFYSA-N 0.000 description 1
- LXLZFQZQRGBWHW-NRFANRHFSA-N O=C(C1CCN(CC[C@H](CCC2)N2C(c([nH]c2c3cccc2)c3F)=O)CC1)c(cc1)ccc1F Chemical compound O=C(C1CCN(CC[C@H](CCC2)N2C(c([nH]c2c3cccc2)c3F)=O)CC1)c(cc1)ccc1F LXLZFQZQRGBWHW-NRFANRHFSA-N 0.000 description 1
- DXOJFDOBOZJGDA-HZPDHXFCSA-N O[C@H]1CN[C@H](CCN(CC2)CCC2c2c[nH]c3c2cccc3)C1 Chemical compound O[C@H]1CN[C@H](CCN(CC2)CCC2c2c[nH]c3c2cccc3)C1 DXOJFDOBOZJGDA-HZPDHXFCSA-N 0.000 description 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012202153A JP5715605B2 (ja) | 2011-09-14 | 2012-09-14 | Ｎ−アシル環状アミン誘導体またはその医薬上許容される塩からなる医薬 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011200374 | 2011-09-14 | ||
| JP2011200374 | 2011-09-14 | ||
| JP2012202153A JP5715605B2 (ja) | 2011-09-14 | 2012-09-14 | Ｎ−アシル環状アミン誘導体またはその医薬上許容される塩からなる医薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013075894A JP2013075894A (ja) | 2013-04-25 |
| JP2013075894A5 JP2013075894A5 (enExample) | 2014-03-13 |
| JP5715605B2 true JP5715605B2 (ja) | 2015-05-07 |
Family
ID=48479653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012202153A Expired - Fee Related JP5715605B2 (ja) | 2011-09-14 | 2012-09-14 | Ｎ−アシル環状アミン誘導体またはその医薬上許容される塩からなる医薬 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP5715605B2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000032987A (ja) * | 1998-07-16 | 2000-02-02 | Dai Ichi Seiyaku Co Ltd | Ｄｎａ |
| CN104140421B (zh) * | 2013-05-08 | 2017-04-05 | 上海医药工业研究院 | 苯并异噻唑类化合物及在制备抗精神分裂症药物中的应用 |
| CN105315267B (zh) * | 2014-07-30 | 2019-06-04 | 江苏恩华药业股份有限公司 | 一种酰胺类衍生物及其应用 |
| JP2019059672A (ja) * | 2015-12-28 | 2019-04-18 | 大日本住友製薬株式会社 | 治療抵抗性うつ病等の治療薬 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3133061A (en) * | 1962-11-13 | 1964-05-12 | Sterling Drug Inc | Piperidine carboxamides and derivatives thereof |
| FR2285883A1 (fr) * | 1974-09-30 | 1976-04-23 | Cerm Cent Europ Rech Mauvernay | Nouveaux composes chimiques a activite bronchospasmolytique et antitussive, et procede pour leur obtention |
| WO1994007496A1 (en) * | 1992-10-07 | 1994-04-14 | Merck & Co., Inc. | Tocolytic oxytocin receptor antagonists |
| MXPA04005988A (es) * | 2001-12-19 | 2004-09-27 | Lundbeck & Co As H | 3,4-dihidro-1h-isoquinolin-2-il-derivados. |
| BRPI0418255A (pt) * | 2003-12-31 | 2007-04-17 | Warner Lambert Co | derivados de piperazina e piperidina n-substituìdos |
-
2012
- 2012-09-14 JP JP2012202153A patent/JP5715605B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013075894A (ja) | 2013-04-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3728238B1 (en) | Sulphonyl urea derivatives as nlrp3 inflammasome modulators | |
| JP5661791B2 (ja) | Ｎ−アシル環状アミン誘導体またはその医薬上許容される塩 | |
| TW201311674A (zh) | 吲唑－及吡咯并吡啶－衍生物及其醫藥用途 | |
| CN102239168B (zh) | 作为h3调节剂的取代的哌啶螺吡咯烷酮和哌啶酮 | |
| JP7253086B2 (ja) | アミノピリジン誘導体およびそれらの選択的ａｌｋ－２阻害剤としての使用 | |
| WO2001070689A1 (en) | DIPHENYLALKYLAMINE DERIVATIVES USEFUL AS OPIOID δ RECEPTOR AGONISTS | |
| BR112021004310A2 (pt) | indazolcarboxamidas como inibidores de cinase | |
| WO2022207935A1 (en) | 2-(3-ethynylbenzyl)-substituted heterocycle derivatives as orexin-2 agonists | |
| CA3234429A1 (en) | Ras inhibitors, compositions and methods of use thereof | |
| JP5715605B2 (ja) | Ｎ−アシル環状アミン誘導体またはその医薬上許容される塩からなる医薬 | |
| CA2555800C (en) | Piperidinylcarbonyl-pyrrolidines and their use as melanocortin agonists | |
| IL303942A (en) | An aromatic heterocyclic substance, a pharmaceutical composition comprising the same, and their use | |
| JP2014506905A (ja) | 新規なベンゾジオキソールピペリジン化合物 | |
| JP2014133739A (ja) | インダゾール誘導体またはピロロピリジン誘導体からなる医薬 | |
| KR101575703B1 (ko) | 모틸린 수용체에 대해 작용제 활성을 가진 옥시인돌 유도체 | |
| JP2022553282A (ja) | Ｔｒｅｋ（ｔｗｉｋ関連ｋ＋チャネル）チャネル機能のモジュレータ | |
| JP2009523747A (ja) | α７ニコチン性アセチルコリン受容体のモジュレーターおよびその治療上の使用 | |
| WO2019129025A1 (zh) | 四氢吡咯类化合物、其制备方法、药物组合物及用途 | |
| JP2013523806A (ja) | スルタム化合物 | |
| AU2006306497A1 (en) | 3-piperidin-4-yl-indole ORL-1 receptor modulators | |
| CN118076599A (zh) | 二噁嗪类及其在治疗gba相关疾病中的用途 | |
| CN120112526A (zh) | 一种egfr降解剂及其制备方法和用途 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140123 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20140123 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20141104 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20141226 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20141226 |
|
| RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20150128 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20150303 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20150313 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 5715605 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: R3D04 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |