JP5711918B2 - Veterinary shampoo - Google Patents

Description

  The present invention relates to an animal shampoo.

  In recent years, lifestyles spent with pets such as dogs, cats, rabbits, ferrets and the like have increased, and the need for technology related to pets has also increased. For example, animal shampoos for keeping pets clean have been developed.

  In general, a preservative is added to an animal shampoo in order to give the animal shampoo an antiseptic effect that prevents the growth of microorganisms in the animal shampoo. A commonly used preservative is paraoxybenzoate.

  In addition, since animal shampoos are intended for animals that move against the will of the owner, the fact that they can be easily removed from the container and easy to handle after being taken out is Unlike, it is an important property for animal shampoos. Animal shampoos are difficult to remove from containers if their viscosity is too high. On the other hand, if the viscosity of the shampoo for animals is too low, it cannot be said that the handling is easy, and the shampoo taken out from the container to the owner's hand will fall down from the hand before being applied to the animal. In addition, even after being applied to an animal, the animal shampoo hangs down from the animal's body or enters the animal's eyes. As described above, it is important that the animal shampoo has an appropriate viscosity in order to be easily taken out from the container and to be easily handled after being taken out.

  In order to adjust the viscosity of the animal shampoo to an appropriate range, a thickener is added to the animal shampoo. A commonly used thickener is a water-soluble polymer. Further, “compounds having an oxyalkylene unit” obtained by adding an alkylene oxide to a diol are known as compounds having a thickening effect (see Patent Documents 1 and 2). The compound having an oxyalkylene unit is added to an external composition and a liquid detergent composition in order to impart an appropriate viscosity (see Patent Documents 1 and 2, respectively).

JP 2008-88063 A (published April 17, 2008) JP 2008-208323 A (published on September 11, 2008)

  As mentioned above, animal shampoos need to have a suitable preservative effect and a suitable viscosity. However, an example in which these effects are exhibited by a single compound has not been known so far. For example, paraoxybenzoic acid ester has a preservative effect but does not have a thickening effect. Moreover, although the water-soluble polymer as a thickener has a thickening effect, it does not have a preservative effect. In the first place, paraoxybenzoic acid esters and many water-soluble polymers are powders. The handling property of the powder deteriorates as the ambient humidity increases. Further, when handling the powder, it is necessary to be careful so that dust does not occur and dust explosion caused by this dust does not occur.

  Since two different components, preservatives and thickeners, must be added, the constituents of animal shampoos are increased. When there are many components, the process in a manufacturing process will become complicated. That is, since the number of times each component contained in the product is weighed or mixed is increased, the number of components constituting the shampoo increases and the shampoo manufacturing process becomes complicated.

  This invention is made | formed in view of said problem, The objective is to provide the technique which manufactures the shampoo for animals safely with few processes.

  The present inventor has found that a specific compound having an oxyalkylene unit has not only a thickening effect but also an antiseptic effect, and has completed the present invention.

  As described above, Patent Documents 1 and 2 disclose that a compound having an oxyalkylene unit has a thickening effect. However, there is no disclosure or suggestion in Patent Documents 1 and 2 that there is a specific compound having a preservative effect as well as a thickening effect. In addition, Patent Documents 1 and 2 include compounds having an oxyalkylene unit in the compounds having an oxyalkylene unit so that a preservative is added to the disclosed external composition and liquid detergent composition. There is no disclosure or suggestion of the technical idea that there is an antiseptic effect.

  That is, the animal shampoo according to the present invention includes an oxyalkylene glycol, a cleaning agent, and a solvent. The oxyalkylene glycol is obtained by adding an alkylene oxide to the hydroxyl group of 1,2-alkylene glycol and / or by addition polymerization. An average value of the number of moles of alkylene oxide bonded to the hydroxyl group is 0.5 to 5.

  Moreover, in the animal shampoo according to the present invention, the average value of the number of moles of bonded alkylene oxide is preferably 1 to 3.

  In the animal shampoo according to the present invention, the alkylene oxide is preferably ethylene oxide.

  Further, in the animal shampoo according to the present invention, 1,2-alkylene glycol is 1,2-octylene glycol, 1,2-nonylene glycol, 1,2-decylene glycol, 1,2-undecylene glycol, Selected from the group consisting of 1,2-dodecylene glycol, 1,2-tridecylene glycol, 1,2-tetradecylene glycol, 1,2-pentadecylene glycol, and 1,2-hexadecylene glycol It is preferable that it is at least one kind.

  According to the present invention, since both a preservative effect and a thickening effect can be imparted to a veterinary shampoo using a single compound, the veterinary shampoo can be easily produced. In addition, the above compound is liquid or paste at normal temperature, so there is no difficulty in handling. That is, this invention provides the shampoo for animals which can be manufactured safely.

  The animal shampoo according to the present invention is an animal shampoo that can be produced by mixing an oxyalkylene glycol, a cleaning agent, and a solvent using a known method. In this oxyalkylene glycol, alkylene oxide is bonded to the hydroxyl group of 1,2-alkylene glycol by at least one of addition and addition polymerization, and the average number of moles of alkylene oxide bonded to the hydroxyl group is 0.5 to 5 It is.

  The “oxyalkylene glycol” used in the present invention is a compound produced by bonding alkylene oxide to the hydroxyl group of 1,2-alkylene glycol by at least one of addition and addition polymerization. The product resulting from at least one of the addition reaction and the addition polymerization reaction is not usually produced as a collection of a single kind of compound, but is usually produced as a collection (ie, a mixture) of a plurality of compounds. That is, as used herein, the term “oxyalkylene glycol” is intended to include a mixture comprising various reaction products based on 1,2-alkylene glycol and alkylene oxide.

  Since 1,2-alkylene glycol has two hydroxyl groups, the compound to be contained in the mixture as described above includes “a plurality of one or both of the two hydroxyl groups of 1,2-alkylene glycol”. Polyoxyalkylene glycols obtained by addition polymerization of alkylene oxides ”,“ oxyalkylene glycols in which one alkylene oxide is added to one or both of the two hydroxyl groups of 1,2-alkylene glycol ”,“ 1,2-alkylene glycols ” Reaction products such as "polyoxyalkylene glycol in which multiple alkylene oxides are added to one hydroxyl group and one alkylene oxide is added to the other hydroxyl group", and alkylene oxide is added to the hydroxyl group of 1,2-alkylene glycol Not done (ie 1, - alkylene glycol itself) "can be mentioned. The oxyalkylene glycol is usually used as a mixture in which these are arbitrarily combined.

  The term “number of moles of alkylene oxide” is intended to mean the number of moles of alkylene oxide linked by at least one of addition and addition polymerization per molecule of 1,2-alkylene glycol constituting the skeleton of “compound having an oxyalkylene unit”. Is done. As described above, “oxyalkylene glycol” is an assembly of a plurality of compounds, and the number of moles of alkylene oxide bonded by at least one of addition and addition polymerization is different for each compound. The term "average number of moles of alkylene oxide" is defined by the number of moles of alkylene oxide contained in the whole mixture and the number of moles of 1,2-alkylene glycol contained in the whole mixture. Specifically, the total number of moles of alkylene oxide used in at least one of the addition reaction and the addition polymerization reaction is the same as the mole of 1,2-alkylene glycol used in at least one of the addition reaction and the addition polymerization reaction. It means a value obtained by dividing by a number (also referred to herein as “average number of moles of alkylene oxide added”).

  The closer the average added mole number of this alkylene oxide is to 1, the stronger the preservative effect of oxyalkylene glycol. For this reason, the average added mole number of alkylene oxide is, for example, 0.5 to 5, preferably 0.8 to 3, and more preferably 1.

  The 1,2-alkylene glycol may be linear or branched. 1,2-alkylene glycol is, for example, 1,2-alkylene glycol having 8 to 16 carbons, specifically, 1,2-octylene glycol, 1,2-nonylene glycol, 1, 2-decylene glycol, 1,2-undecylene glycol, 1,2-dodecylene glycol, 1,2-tridecylene glycol, 1,2-tetradecylene glycol, 1,2-pentadecylene glycol, and 1 , 2-hexadecylene glycol is preferably at least one selected from the group consisting of 1,2-dodecylene glycol, and more preferably 1,2-dodecylene glycol.

  The alkylene oxide may be linear or branched. The alkylene oxide is, for example, ethylene oxide, propylene oxide, butylene oxide, pentylene oxide, hexylene oxide, etc., preferably ethylene oxide and / or propylene oxide, and more preferably ethylene oxide.

  Suitable oxyalkylene glycols are “1,2-alkylene glycol is 1,2-dodecylene glycol, the alkylene oxide is ethylene oxide, and the average added mole number of ethylene oxide is 1” polyoxyethylene dodecylene Glycol.

  Such oxyalkylene glycols are known. For example, polyoxyethylene dodecylene glycol having an average added mole number of ethylene oxide of 1 is “New Pole DDE-10” (manufactured by Sanyo Chemical Industries, Ltd.). Can be obtained as

  An oxyalkylene glycol having an average added mole number of alkylene oxide within the above-described range exhibits not only an antiseptic effect but also a thickening effect. That is, the oxyalkylene glycol used in the present invention serves as both a preservative and a thickener. By using such an oxyalkylene glycol, the number of components of the animal shampoo can be reduced, and as a result, the production of the animal shampoo can be simplified. In addition, since the oxyalkylene glycol used in the present invention is liquid or paste at room temperature, there is no need to pay attention to humidity during handling, dusting and dust explosion, so it is safer to manufacture animal shampoos. Make things.

  The amount of oxyalkylene glycol contained in the animal shampoo according to the present invention is preferably 1 to 5%, more preferably 2 to 3%, based on the total mass of the shampoo to be produced. If the oxyalkylene glycol within this range is contained, an appropriate viscosity and antiseptic effect of the animal shampoo according to the present invention can be realized. Appropriate viscosity is preferably 200 to 2000 mPas, preferably 300 to 1500 mPas when measured at 30 rpm or 12 rpm using a B type viscometer (rotor No. 2) manufactured by Toki Sangyo Co., Ltd. More preferred. The antiseptic effect is that which prevents the growth of microorganisms and suppresses the decay of the product in the product containing the preservative. Whether or not the animal shampoo has such an antiseptic effect can be examined, for example, by inoculating the animal shampoo with a microorganism and observing whether or not the microorganism grows.

  The cleaning agent contained in the animal shampoo according to the present invention is not particularly limited as long as it is a known cleaning agent. Examples of the cleaning agent include anionic surfactants, nonionic surfactants, cationic surfactants, and amphoteric surfactants.

  Examples of the anionic surfactant include sodium polyoxyethylene lauryl ether sulfate, sodium polyoxyethylene lauryl ether acetate, N-coconut oil fatty acid acyl-L-glutamic acid triethanolamine, lauroylmethyl-β-alanine sodium, polyoxy Examples thereof include disodium lauryl ethylenesulfosuccinate and lauroyl hydrolyzed silk sodium. Examples of nonionic surfactants include coconut oil fatty acid diethanolamide, glyceryl monostearate, and polyethylene glycol distearate. Examples of the cationic surfactant include cetyltrimethylammonium chloride, dimethylaminopropylamide stearate, and behenyltrimethylammonium chloride. Examples of amphoteric surfactants include coconut oil fatty acid amidopropyl betaine, sodium lauroyl-β-alanine, sodium β-laurylaminopropionate, amidopropyl betaine laurate, and the like.

  The amount of the detergent to be included in the animal shampoo according to the present invention varies depending on the type thereof, but is preferably 3 to 40%, preferably 5 to 30%, based on the total mass of the shampoo to be produced. More preferably.

  Although the solvent contained in the animal shampoo according to the present invention is not particularly limited, it is water or a hydrophilic solvent, and when each component such as a cleaning agent is a solution diluted with these solvents, it is contained in the solution. Including the solvent to be used. The amount of the solvent (including the solvent) contained in the animal shampoo according to the present invention is preferably 50 to 95%, preferably 60 to 90%, based on the total mass of the shampoo to be produced. More preferred.

  Moreover, the animal shampoo according to the present invention may optionally contain additives other than the above-described oxyalkylene glycol, detergent and solvent depending on the purpose.

  Examples of additives include cleaning aids, humectants, pH adjusters, ultraviolet absorbers, pearlizing agents, silicone agents, fungicides, insecticides, fragrances, plant extracts, colorants, and the like. Examples of the cleaning aid include chelating agents such as ethylenediaminetetraacetate (EDTA), citrate, and phosphonate. Examples of the humectant include glycerin, concentrated glycerin, sorbitol, propylene glycol, and 1,3-butylene glycol. Examples of the pH adjuster include triethanolamine and citric acid. Examples of the ultraviolet absorber include benzophenone derivatives, p-aminobenzoic acid derivatives, salicylic acid derivatives, and the like. Examples of the pearling agent include ethylene glycol distearate. Examples of the silicone agent include dimethyl polysiloxane, methyl hydrogen polysiloxane, and methylphenyl polysiloxane. Examples of the insecticide include allethrin, phenothrin, pyrethrin, etofenprox and the like. Examples of bactericides include salicylic acid, alkyldiaminoethylglycine hydrochloride, chloroxylenol and the like. Examples of the plant extract include licorice extract powder, aloe extract, kawara mugwort extract and the like. Examples of the colorant include tar dyes.

  When the animal shampoo according to the present invention contains an additive, the total amount of the additive to be included is 20% or less based on the total mass of the shampoo to be produced.

  The pH of the animal shampoo according to the present invention is not particularly limited, but is preferably 4 to 9 from the viewpoint of animal safety.

  The dosage form of the animal shampoo according to the present invention is not particularly limited, and for example, it can be a dosage form according to the purpose such as liquid, gel or cream. Examples of the container filled with the animal shampoo according to the present invention include a bottle, a container with a pump, a tube, and a pump former.

  In addition, although it is preferable that this invention is provided as an aspect (namely, composition) in which the component which comprises the animal shampoo which concerns on this invention is contained in one substance, these separated components are put together. It may be provided as a packaged form (ie a kit). The kit which concerns on this invention should just be equipped with the oxyalkylene glycol, the cleaning agent, and the solvent, and these may be filled into the separate container and may be filled into the same container.

  The animal shampoo according to the present invention is intended to be applied to non-human animals. That is, unless otherwise stated, as used herein, the term “animal” is intended to be a “non-human animal”. Examples of the “non-human animal” include mammals other than humans and birds. Mammals other than humans are not particularly limited. For example, cattle, wild boars, pigs, sheep, goats, etc., hoofs, horses, etc. And rabbits such as rabbits, and meat such as dogs, cats, ferrets, and the like. Moreover, it does not specifically limit as birds, For example, a duck, a chicken, a pigeon, a parakeet etc. can be mentioned. Further, these non-human animals are not limited to domestic animals or companion animals (companion animals), and may be wild animals. In a preferred embodiment, the animal shampoo according to the present invention is applied to small animals. The non-human animal to which the animal shampoo according to the present invention is applied may be any of small animals to large animals. Good. Here, “small animals” are intended to be animals such as dogs, cats, rabbits, chickens, hamsters, ferrets, etc., and “large animals” are, for example, cows, horses, pigs, sheep, goats, etc. Such animals are intended.

  The present invention is not limited to the above-described embodiments, and various modifications are possible within the scope shown in the claims, and embodiments obtained by appropriately combining technical means disclosed in different embodiments. Is also included in the technical scope of the present invention.

  EXAMPLES Hereinafter, although an Example demonstrates this invention further in detail, this invention is not limited to this.

  First, formulation examples of animal shampoos according to the present invention or comparative formulation examples (comparative examples) are shown. In addition, in the polyoxyethylene dodecylene glycol shown in these examples, “New Pole DDE-10” manufactured by Sanyo Chemical Industries with an average addition mole number of ethylene oxide of 1 was used.

  In addition,% in the following manufacture example represents the mass%.

[Production Example 1]
Polyoxyethylene dodecylene glycol, polyoxyethylene lauryl ether sodium sulfate (25% solution) (Sanyo Kasei Kogyo Co., Ltd.), coconut oil fatty acid amidopropyl betaine (29% solution) ) (Sanyo Chemical Industry Co., Ltd.), concentrated glycerin (Kao Chemical Co., Ltd.), and water were mixed to prepare an animal shampoo.

[Production Example 2]
As in Production Example 1, polyoxyethylene dodecylene glycol, polyoxyethylene lauryl ether sodium sulfate (25% solution), polyoxyethylene sulfosuccinate disodium lauryl (30%) so as to have the blending amounts shown in Table 1. Solution), lauric acid amidopropyl betaine solution (30% solution), coconut oil fatty acid diethanolamide, ethylene glycol distearate, glycerin, citric acid, aloe extract, Chinese mugwort extract, fragrance, and water to prepare an animal shampoo did.

[Production Example 3]
In the same manner as in Production Example 1, polyoxyethylene dodecylene glycol, polyoxyethylene lauryl ether sodium sulfate (25% solution), N-coconut oil fatty acid acyl-L-glutamic acid tri so as to have the blending amounts shown in Table 1. Ethanolamine solution (30% solution), dimethylaminopropylamide stearate, amidopropylbetaine laurate solution (30% solution), coconut oil fatty acid diethanolamide, concentrated glycerin, citric acid, alkyldiaminoethylglycine hydrochloride (40% solution) A shampoo for animals was prepared by mixing fragrance, water, and water.

[Production Example 4]
As in Production Example 1, polyoxyethylene dodecylene glycol, polyoxyethylene lauryl ether sodium acetate (28% solution), lauroylmethyl-β-alanine sodium (30% solution) ), Cetyltrimethylammonium chloride (30% solution), amidopropyl betaine laurate solution (30% solution), ethylene glycol distearate, lauroyl hydrolyzed silk sodium solution (20% solution), concentrated glycerin, citric acid and water An animal shampoo was prepared.

[Production Example 5]
As in Production Example 1, polyoxyethylene dodecylene glycol, polyoxyethylene lauryl ether sodium acetate (28% solution), N-coconut oil fatty acid acyl-L-glutamic acid triethanol so as to have the blending amounts shown in Table 1. Mix amine solution (30% solution), cetyltrimethylammonium chloride (30% solution), coconut oil fatty acid amide propylbetaine solution (29% solution), coconut oil fatty acid diethanolamide, concentrated glycerin, citric acid, allethrin, fragrance and water. An animal shampoo was prepared.

[Comparative Example 1]
Animal shampoos were prepared so as to have the blending amounts shown in Table 1 in the same manner as in Production Example 1 except that methyl paraoxybenzoate (Ueno Pharmaceutical Co., Ltd.) was used instead of polyoxyethylene dodecylene glycol.

[Comparative Example 2]
An animal shampoo was prepared so as to have the blending amounts shown in Table 1 in the same manner as in Production Example 1, except that purified water was used instead of polyoxyethylene dodecylene glycol.

[Contrast of production example and comparative example]
The viscosity of the animal shampoo prepared in Production Example 1 was measured at 25 ° C. at 30 rpm or 12 rpm using a B-type viscose watch (rotor No. 2) manufactured by Toki Sangyo Co., Ltd. The measured viscosity was 1190 (mPas), and it was found to have an appropriate viscosity as an animal shampoo. Similarly, when the viscosities of the animal shampoos prepared in Comparative Examples 1 and 2 were measured, they were 20 (mPas) and 4 (mPas), respectively.

  The antiseptic effect of the animal shampoo prepared in Production Example 1 was examined as follows. That is, the petri dish containing the agar medium was left open for 3 hours, and then the lid was closed, and the bacteria were cultured in an environment of 25 ° C. and 98% humidity. Next, for the bacteria considered to be the same, the agar medium was cut to 5 × 5 mm so that the mycelia with the same extended state contained the tip of the mycelium. Separately, 1 g of the animal shampoo prepared in Production Example 1 was applied on an agar medium prepared and spread over the entire surface of the agar medium. Thereafter, one piece of the agar medium containing the test bacteria cut to 5 × 5 mm was inoculated into the agar medium.

  After inoculation, the cells were cultured for 2 days under the aforementioned culture conditions, and the growth state of the bacteria was observed with the naked eye. The results of bacterial growth by visual observation were determined in three stages as follows.

  +: The growth of bacteria was clearly observed.

  ±: Slight growth of bacteria was observed.

  -: No growth of bacteria was observed.

  As shown in Table 2, when the animal shampoo prepared in Production Example 1 was used, no bacterial growth was observed. From this result, the antiseptic effect of the animal shampoo prepared in Production Example 1 was recognized, and it was found that the animal shampoo had a sufficient antiseptic effect. Moreover, when the antiseptic effect of the animal shampoo prepared in Comparative Example 1 was examined in the same manner as the animal shampoo prepared in Production Example 1, the antiseptic effect was observed. Moreover, when the antiseptic effect of the animal shampoo prepared in Comparative Example 2 was examined in the same manner as the animal shampoo prepared in Production Example 1, the antiseptic effect was not exhibited.

  Table 2 below shows the viscosities of the animal shampoos prepared in Production Example 1 and Comparative Examples 1 and 2, results of bacterial growth, and antiseptic effects.

  In Production Example 1, the same amount of polyoxyethylene dodecylene glycol is used instead of methyl paraoxybenzoate used in Comparative Example 1. The viscosity in Comparative Example 1 is significantly lower than that in Production Example 1. Thus, although polyoxyethylene dodecylene glycol has a thickening effect, it cannot be said that methyl paraoxybenzoate has a thickening effect.

  In Comparative Example 2, the polyoxyethylene dodecylene glycol of Production Example 1 is not used, and purified water is substituted for the amount. From the comparison between the two, it can be seen that the preservative effect is exhibited only in Production Example 1. Thus, polyoxyethylene dodecylene glycol has an antiseptic effect.

  The present invention can be suitably used for keeping an animal clean by washing the body surface of an animal (including body hair).

Claims (3)

An animal shampoo containing oxyalkylene glycol, a detergent, and a solvent,
In the oxyalkylene glycol, ethylene oxide is bonded to the hydroxyl group of 1,2-alkylene glycol by at least one of addition and addition polymerization, and the average value of the number of moles of the ethylene oxide bonded to the hydroxyl group is 1 to 3. The
The 1,2-alkylene glycol is 1,2-undecylene glycol, 1,2-dodecylene glycol, 1,2-tridecylene glycol, 1,2-tetradecylene glycol, 1,2-pentadecylene glycol. And at least one selected from the group consisting of 1,2-hexadecylene glycol,
Animal shampoo viscosity wherein 300~1500mPas der Rukoto. The animal shampoo according to claim 1, wherein the animal shampoo contains no thickener and preservative other than the oxyalkylene glycol . The animal shampoo according to claim 1 or 2, comprising 2 to 3% by mass of the oxyalkylene glycol .