JP5680110B2 - 体外サンプルの断端評価 - Google Patents
体外サンプルの断端評価 Download PDFInfo
- Publication number
- JP5680110B2 JP5680110B2 JP2012551362A JP2012551362A JP5680110B2 JP 5680110 B2 JP5680110 B2 JP 5680110B2 JP 2012551362 A JP2012551362 A JP 2012551362A JP 2012551362 A JP2012551362 A JP 2012551362A JP 5680110 B2 JP5680110 B2 JP 5680110B2
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- sample holder
- stump
- magnet
- coil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 238000011156 evaluation Methods 0.000 title claims description 8
- 238000000338 in vitro Methods 0.000 title description 2
- 206010028980 Neoplasm Diseases 0.000 claims description 36
- 238000000034 method Methods 0.000 claims description 13
- 238000003384 imaging method Methods 0.000 claims description 12
- 239000011159 matrix material Substances 0.000 claims description 11
- 230000003068 static effect Effects 0.000 claims description 8
- 238000005259 measurement Methods 0.000 claims description 6
- 230000002093 peripheral effect Effects 0.000 claims description 4
- 238000002595 magnetic resonance imaging Methods 0.000 description 35
- 210000001519 tissue Anatomy 0.000 description 32
- 238000010586 diagram Methods 0.000 description 20
- 201000011510 cancer Diseases 0.000 description 8
- 238000001208 nuclear magnetic resonance pulse sequence Methods 0.000 description 7
- 238000009792 diffusion process Methods 0.000 description 6
- 210000000481 breast Anatomy 0.000 description 5
- 238000001356 surgical procedure Methods 0.000 description 5
- 230000005540 biological transmission Effects 0.000 description 4
- 230000035945 sensitivity Effects 0.000 description 4
- 230000001575 pathological effect Effects 0.000 description 3
- 238000002604 ultrasonography Methods 0.000 description 3
- 230000002238 attenuated effect Effects 0.000 description 2
- 238000002405 diagnostic procedure Methods 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- 230000005415 magnetization Effects 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 230000002123 temporal effect Effects 0.000 description 2
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 238000004435 EPR spectroscopy Methods 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000004624 confocal microscopy Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 238000002597 diffusion-weighted imaging Methods 0.000 description 1
- 210000001165 lymph node Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012014 optical coherence tomography Methods 0.000 description 1
- 238000010827 pathological analysis Methods 0.000 description 1
- 238000012335 pathological evaluation Methods 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 238000001931 thermography Methods 0.000 description 1
- 239000000439 tumor marker Substances 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/30—Sample handling arrangements, e.g. sample cells, spinning mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
- G01R33/56375—Intentional motion of the sample during MR, e.g. moving table imaging
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
- G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
- G01R33/341—Constructional details, e.g. resonators, specially adapted to MR comprising surface coils
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
- G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
- G01R33/341—Constructional details, e.g. resonators, specially adapted to MR comprising surface coils
- G01R33/3415—Constructional details, e.g. resonators, specially adapted to MR comprising surface coils comprising arrays of sub-coils, i.e. phased-array coils with flexible receiver channels
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Health & Medical Sciences (AREA)
- High Energy & Nuclear Physics (AREA)
- General Health & Medical Sciences (AREA)
- Signal Processing (AREA)
- Engineering & Computer Science (AREA)
- Radiology & Medical Imaging (AREA)
- Vascular Medicine (AREA)
- Optics & Photonics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30015610P | 2010-02-01 | 2010-02-01 | |
| US61/300,156 | 2010-02-01 | ||
| PCT/US2011/023101 WO2011094659A2 (en) | 2010-02-01 | 2011-01-31 | Tumor margin assessment of ex -vivo sample |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013519073A JP2013519073A (ja) | 2013-05-23 |
| JP2013519073A5 JP2013519073A5 (enExample) | 2014-02-27 |
| JP5680110B2 true JP5680110B2 (ja) | 2015-03-04 |
Family
ID=44010151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012551362A Active JP5680110B2 (ja) | 2010-02-01 | 2011-01-31 | 体外サンプルの断端評価 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9310450B2 (enExample) |
| EP (1) | EP2565663B1 (enExample) |
| JP (1) | JP5680110B2 (enExample) |
| WO (1) | WO2011094659A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10204415B2 (en) | 2012-01-16 | 2019-02-12 | Koninklijke Philips N.V. | Imaging apparatus |
| ES2878548T3 (es) * | 2012-02-26 | 2021-11-19 | Caliber Imaging & Diagnostics Inc | Platina para muestras de tejido para un microscopio de seccionamiento óptico |
| US9689817B2 (en) * | 2012-03-21 | 2017-06-27 | Clear-Cut Medical Ltd. | MRI system for margin assessment of ex-vivo sample |
| US9677869B2 (en) | 2012-12-05 | 2017-06-13 | Perimeter Medical Imaging, Inc. | System and method for generating a wide-field OCT image of a portion of a sample |
| JP2019512083A (ja) * | 2016-02-04 | 2019-05-09 | クリア−カット メディカル リミテッド | 永続磁石配列を使用したmri画像化システム |
| WO2018134793A1 (en) * | 2017-01-23 | 2018-07-26 | Clear-Cut Medical Ltd. | System for ex-vivo nmr inspection of removed tissue |
| EP3655748B1 (en) | 2017-07-18 | 2023-08-09 | Perimeter Medical Imaging, Inc. | Sample container for stabilizing and aligning excised biological tissue samples for ex vivo analysis |
| WO2019222194A1 (en) * | 2018-05-15 | 2019-11-21 | Intuitive Surgical Operations, Inc. | Systems and methods for determining an arrangement of explanted tissue and for displaying tissue information |
| WO2021191748A1 (en) | 2020-03-22 | 2021-09-30 | Clear-Cut Medical Ltd. | Method for extracting multiple t2* values from single set of cpmg data |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63270037A (ja) * | 1987-04-28 | 1988-11-08 | Olympus Optical Co Ltd | 内視鏡 |
| JPH0435645A (ja) * | 1990-05-31 | 1992-02-06 | Toshiba Corp | 磁気共鳴イメージング装置 |
| US5162103A (en) | 1992-01-17 | 1992-11-10 | Auburn International, Inc. | Sample holder compactor for industrial NMR analysis |
| DE4225001C1 (de) * | 1992-07-29 | 1993-11-18 | Siemens Ag | Stereotaktische Zusatzeinrichtung für Kernspintomographen |
| US6032068A (en) * | 1998-02-19 | 2000-02-29 | The Board Of Trustees Of The Leland Stanford Junior University | Non-invasive measurement of frozen tissue temperature using MRI signal |
| WO2000015021A2 (en) * | 1998-09-14 | 2000-03-23 | Lucid, Inc. | Imaging of surgical biopsies |
| US7227630B1 (en) | 1998-09-14 | 2007-06-05 | Lucid, Inc. | Imaging of surgical biopsies |
| EP1169630B1 (en) | 1999-02-17 | 2017-02-01 | Lucid, Inc. | Cassette for facilitating optical sectioning of a retained tissue specimen |
| US6289682B1 (en) * | 1999-08-25 | 2001-09-18 | David C. Rada | Specimen preparation apparatus |
| US8068896B2 (en) * | 2005-02-25 | 2011-11-29 | Intramedical Imaging, Llc | Detection of radiation labeled sites using a radiation detection probe or camera incorporating a solid state photo-multiplier |
| JP2006247113A (ja) * | 2005-03-10 | 2006-09-21 | Gunma Univ | 腫瘍検出のための画像形成方法及び画像形成ソフトウェア |
| US8038595B2 (en) * | 2006-01-25 | 2011-10-18 | Beth Israel Deaconess Medical Center | Devices and methods for tissue transplant and regeneration |
| WO2007142678A1 (en) | 2006-06-05 | 2007-12-13 | The Johns Hopkins University | Compression device for enhancing normal/abnormal tissue contrast in mri including devices and methods related thereto |
| JP5170686B2 (ja) * | 2006-09-29 | 2013-03-27 | 学校法人慶應義塾 | 核磁気共鳴法を用いた測定装置および測定方法 |
| JP4718410B2 (ja) * | 2006-10-16 | 2011-07-06 | サクラファインテックジャパン株式会社 | 摘出生体組織形状保持材及び生体組織の固定方法 |
| JP5170617B2 (ja) * | 2007-04-24 | 2013-03-27 | 独立行政法人産業技術総合研究所 | 片側開放型磁気回路 |
| US8463361B2 (en) * | 2007-05-24 | 2013-06-11 | Lifewave, Inc. | System and method for non-invasive instantaneous and continuous measurement of cardiac chamber volume |
| US8983580B2 (en) * | 2008-01-18 | 2015-03-17 | The Board Of Trustees Of The University Of Illinois | Low-coherence interferometry and optical coherence tomography for image-guided surgical treatment of solid tumors |
| US8208709B2 (en) * | 2008-04-17 | 2012-06-26 | The Ohio State University Research Foundation | System and method for improved real-time cine imaging |
| JP5335280B2 (ja) * | 2008-05-13 | 2013-11-06 | キヤノン株式会社 | 位置合わせ処理装置、位置合わせ方法、プログラム、及び記憶媒体 |
| US8688193B2 (en) * | 2008-06-26 | 2014-04-01 | Allegheny-Singer Research Institute | Magnetic resonance imager, method and program which continuously applies steady-state free precession to k-space |
-
2011
- 2011-01-31 EP EP12181943.7A patent/EP2565663B1/en active Active
- 2011-01-31 JP JP2012551362A patent/JP5680110B2/ja active Active
- 2011-01-31 US US13/522,353 patent/US9310450B2/en active Active
- 2011-01-31 WO PCT/US2011/023101 patent/WO2011094659A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011094659A2 (en) | 2011-08-04 |
| EP2565663A1 (en) | 2013-03-06 |
| US20120299591A1 (en) | 2012-11-29 |
| JP2013519073A (ja) | 2013-05-23 |
| EP2565663B1 (en) | 2016-12-14 |
| US9310450B2 (en) | 2016-04-12 |
| WO2011094659A3 (en) | 2012-01-05 |
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