JP5677855B2 - 新規抗感染誘導体、それらの製造方法、それらを含有する医薬組成物、及び治療におけるその誘導体の使用 - Google Patents

新規抗感染誘導体、それらの製造方法、それらを含有する医薬組成物、及び治療におけるその誘導体の使用 Download PDF

Info

Publication number
JP5677855B2
JP5677855B2 JP2010545538A JP2010545538A JP5677855B2 JP 5677855 B2 JP5677855 B2 JP 5677855B2 JP 2010545538 A JP2010545538 A JP 2010545538A JP 2010545538 A JP2010545538 A JP 2010545538A JP 5677855 B2 JP5677855 B2 JP 5677855B2
Authority
JP
Japan
Prior art keywords
group
compound
general formula
alkyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2010545538A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011511050A5 (https=
JP2011511050A (ja
Inventor
ブルナドゥ,ジャン
ベルナルデス−ジェニッソン,バニア
ドゥレヌ,タマラ
ケマル,アネック
Original Assignee
サントル ナシオナル ドゥ ラ ルシェルシェサイアンティフィク(セエヌエールエス)
サントル ナシオナル ドゥ ラ ルシェルシェサイアンティフィク(セエヌエールエス)
ユニベルシテ ポール サバティエ トゥールーズ トロワズィエーム
ユニベルシテ ポール サバティエ トゥールーズ トロワズィエーム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by サントル ナシオナル ドゥ ラ ルシェルシェサイアンティフィク(セエヌエールエス), サントル ナシオナル ドゥ ラ ルシェルシェサイアンティフィク(セエヌエールエス), ユニベルシテ ポール サバティエ トゥールーズ トロワズィエーム, ユニベルシテ ポール サバティエ トゥールーズ トロワズィエーム filed Critical サントル ナシオナル ドゥ ラ ルシェルシェサイアンティフィク(セエヌエールエス)
Publication of JP2011511050A publication Critical patent/JP2011511050A/ja
Publication of JP2011511050A5 publication Critical patent/JP2011511050A5/ja
Application granted granted Critical
Publication of JP5677855B2 publication Critical patent/JP5677855B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/08Antibacterial agents for leprosy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2010545538A 2008-02-07 2009-02-06 新規抗感染誘導体、それらの製造方法、それらを含有する医薬組成物、及び治療におけるその誘導体の使用 Expired - Fee Related JP5677855B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0850778A FR2927331B1 (fr) 2008-02-07 2008-02-07 Nouveaux derives anti-infectieux, leur procede de preparation, compositions pharmaceutiques les contenant et leurs utilisations en therapeutique.
FR0850778 2008-02-07
PCT/FR2009/050195 WO2009101345A1 (fr) 2008-02-07 2009-02-06 Nouveaux dérivés anti-infectieux, leur procédé de préparation, compositions pharmaceutiques les contenant et leurs utilisations en thérapeutique

Publications (3)

Publication Number Publication Date
JP2011511050A JP2011511050A (ja) 2011-04-07
JP2011511050A5 JP2011511050A5 (https=) 2014-03-06
JP5677855B2 true JP5677855B2 (ja) 2015-02-25

Family

ID=39745633

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010545538A Expired - Fee Related JP5677855B2 (ja) 2008-02-07 2009-02-06 新規抗感染誘導体、それらの製造方法、それらを含有する医薬組成物、及び治療におけるその誘導体の使用

Country Status (6)

Country Link
US (1) US8710073B2 (https=)
EP (1) EP2240449B1 (https=)
JP (1) JP5677855B2 (https=)
CA (1) CA2715138A1 (https=)
FR (1) FR2927331B1 (https=)
WO (1) WO2009101345A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR102012033811A8 (pt) * 2012-12-28 2019-12-24 Uniao Brasileira De Educacao E Assistencia Mantenedora Da Puc Rs compostos, uso, composição farmacêutica inibidora de redutase em microorganismos, ligante de inha, e, método para obtenção de ligantes de inha
BR102013006007A2 (pt) * 2013-03-13 2014-11-11 Ubea Compostos, uso, composição farmacêutica inibidora de redutase em microorganismos, ligante de inha, e, método para obtenção de ligantes de inha a partir de derivados de acetamida, ureia, fenol e carboxamida
GB201322334D0 (en) * 2013-12-17 2014-01-29 Agency Science Tech & Res Maleimide derivatives as modulators of WNT pathway

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6291586B2 (en) 1996-05-03 2001-09-18 3M Innovative Properties Company Amide functional ultraviolet light absorbers for polyurethanes and polyureas
US6328793B1 (en) * 2000-08-03 2001-12-11 Xerox Corporation Phase change inks
CN101534808A (zh) * 2005-06-27 2009-09-16 拜维尔实验室国际有限公司 丁氨苯丙酮盐的改良释放配制品
EP2687533B1 (en) * 2006-07-20 2017-07-19 Debiopharm International SA Acrylamide derivatives as FAB I inhibitors

Also Published As

Publication number Publication date
US8710073B2 (en) 2014-04-29
US20110092536A1 (en) 2011-04-21
FR2927331B1 (fr) 2011-05-20
CA2715138A1 (fr) 2009-08-20
JP2011511050A (ja) 2011-04-07
WO2009101345A1 (fr) 2009-08-20
EP2240449A1 (fr) 2010-10-20
FR2927331A1 (fr) 2009-08-14
EP2240449B1 (fr) 2016-01-06

Similar Documents

Publication Publication Date Title
EP1765795B1 (en) Alkynyl derivatives as modulators of metabotropic glutamate receptors
JP4812745B2 (ja) アリール及びヘテロアリールピペリジンカルボン酸誘導体、その製造並びにfaah酵素阻害剤としてのその使用
CN113195053A (zh) 氨基酸化合物和使用方法
EP2158201B1 (fr) Derives de 7-alkynyl-1,8-naphthyridones, leur preparation et leur application en therapeutique
JP2017501236A (ja) RORγ調節因子としてのピロリジニルスルホン誘導体およびその使用
TW200813010A (en) Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors
TW200906401A (en) Triazolopyridine carboxamide derivatives, preparation thereof and therapeutic use thereof
JP2017509689A (ja) シクロヘキシルスルホンRORγ調節因子
JP2017508782A (ja) 炭素環式スルホンRORγ調節因子
TW200930703A (en) Quinolone derivative
CN113226462B (zh) 作为vanin抑制剂的杂芳族化合物
JP3465825B2 (ja) Pde▲iv▼阻害剤としてのトリアリールエタン誘導体
US6627767B2 (en) Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors
JPH01500834A (ja) アザインドール及びインドリジン誘導体、その製造方法及び薬剤としてのその用途
KR20230024886A (ko) 항바이러스 1,3-다이-옥소-인덴 화합물
JPS63275561A (ja) 置換ピロール類
AU2018358642A1 (en) Anti-infective heterocyclic compounds and uses thereof
JP2712107B2 (ja) 二置換ピリジン類
JP2007513120A (ja) ピロール化合物
US6977262B2 (en) Dihydropyrazolopyridine compounds and pharmaceutical use thereof
JP5677855B2 (ja) 新規抗感染誘導体、それらの製造方法、それらを含有する医薬組成物、及び治療におけるその誘導体の使用
JP2005501800A (ja) ジヒドロピラゾロピリジン化合物およびその医薬用途
US12297193B2 (en) PTPN2/PTP1B degrader and therapeutic method thereof
CN102858748B (zh) 阿尔茨海默病的治疗剂或预防剂
JP5291721B2 (ja) 置換3−ヒドロキシピリジン及びその医薬組成物

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20120202

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20131010

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20131022

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20140120

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140722

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20141021

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20141202

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20150105

R150 Certificate of patent or registration of utility model

Ref document number: 5677855

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

LAPS Cancellation because of no payment of annual fees