JP5658566B2 - 計装ピペット先端 - Google Patents

計装ピペット先端 Download PDF

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Publication number
JP5658566B2
JP5658566B2 JP2010526963A JP2010526963A JP5658566B2 JP 5658566 B2 JP5658566 B2 JP 5658566B2 JP 2010526963 A JP2010526963 A JP 2010526963A JP 2010526963 A JP2010526963 A JP 2010526963A JP 5658566 B2 JP5658566 B2 JP 5658566B2
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Japan
Prior art keywords
pipette tip
fluid
pipette
sample
fluid path
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Japanese (ja)
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JP2010540226A (ja
JP2010540226A5 (enExample
Inventor
アイリフェ,ハロルド・イー
キング,カーティス・エス
Original Assignee
イーアイ・スペクトラ・エルエルシー
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Publication of JP2010540226A5 publication Critical patent/JP2010540226A5/ja
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0275Interchangeable or disposable dispensing tips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016Control of the volume dispensed or introduced
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0645Electrodes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/1048General features of the devices using the transfer device for another function
    • G01N2035/1062General features of the devices using the transfer device for another function for testing the liquid while it is in the transfer device

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
JP2010526963A 2007-09-29 2008-09-26 計装ピペット先端 Active JP5658566B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99575207P 2007-09-29 2007-09-29
US60/995,752 2007-09-29
PCT/US2008/011205 WO2009045343A1 (en) 2007-09-29 2008-09-26 Instrumented pipette tip

Publications (3)

Publication Number Publication Date
JP2010540226A JP2010540226A (ja) 2010-12-24
JP2010540226A5 JP2010540226A5 (enExample) 2011-05-26
JP5658566B2 true JP5658566B2 (ja) 2015-01-28

Family

ID=40526505

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010526963A Active JP5658566B2 (ja) 2007-09-29 2008-09-26 計装ピペット先端

Country Status (6)

Country Link
US (1) US8015887B2 (enExample)
EP (1) EP2195114B1 (enExample)
JP (1) JP5658566B2 (enExample)
CN (1) CN102316988B (enExample)
ES (1) ES2624930T3 (enExample)
WO (1) WO2009045343A1 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009070246A1 (en) * 2007-11-27 2009-06-04 E.I Spectra, Llc Fluorescence-based pipette instrument
SG175303A1 (en) 2009-04-27 2011-11-28 Ei Spectra Llc Pipette instrument
US8602644B2 (en) * 2009-05-08 2013-12-10 University Of North Texas Multifunctional micropipette biological sensor
AU2010295250A1 (en) * 2009-09-18 2012-04-05 Minifab (Australia) Pty Ltd Instrumented pipette
DE102009049783A1 (de) * 2009-10-19 2011-04-21 Eppendorf Ag Elektrisch leitfähige Pipettenspitze
US20120019270A1 (en) * 2010-07-21 2012-01-26 Amodei Dario G Microfabricated pipette and method of manufacture
US20130035660A1 (en) 2011-08-01 2013-02-07 Alcyone Lifesciences, Inc. Multidirectional microfluidic drug delivery devices with conformable balloons
DK2809782T3 (da) 2012-01-31 2017-11-20 The Rogosin Inst Inc Forbedret fremgangsmåde til fremstilling af makrokugler
US9333502B1 (en) 2012-09-13 2016-05-10 E. I. Spectra, Llc Sample-acquiring microfluidic tester
EP2934627B1 (en) 2012-12-18 2021-04-07 Alcyone Lifesciences, Inc. Devices and methods for reducing or preventing backflow in a delivery system
CN110215595B (zh) 2013-06-17 2022-04-12 亚克安娜治疗学有限公司 导管末梢保护系统和立体定向固定装置
ES2738298T3 (es) 2013-07-31 2020-01-21 Alcyone Lifesciences Inc Sistemas y métodos de suministro de fármacos, tratamiento y monitoreo
EP3058337B1 (en) 2013-10-15 2019-02-20 Ecole Polytechnique Federale de Lausanne (EPFL) Sensing tip with electrical impedance sensor
US10806396B2 (en) 2015-01-26 2020-10-20 Alcyone Lifesciences, Inc. Drug delivery methods with tracer
DE102015214566A1 (de) * 2015-07-30 2017-02-02 Hamilton Bonaduz Ag Pipettiervorrichtung zur Pipettierung kleiner Flüssigkeitsvolumina
WO2017120167A1 (en) 2016-01-04 2017-07-13 Alcyone Lifesciences, Inc. Methods and devices for treating stroke
DE102016201181B3 (de) * 2016-01-27 2017-05-04 Albert-Ludwigs-Universität Freiburg Röhre mit einer mikrofluidischen Struktur
JP6842242B2 (ja) * 2016-03-22 2021-03-17 株式会社アイカムス・ラボ 分注システム
US10480979B2 (en) * 2016-05-25 2019-11-19 Agilent Technologies, Inc. Flow meters, flow meter cartridges, and related methods
PL3335795T3 (pl) * 2016-12-16 2019-09-30 Eppendorf Ag Sposób dozowania cieczy za pomocą pipety i strzykawki oraz pipeta do uruchamiania strzykawki do dozowania cieczy
US10910749B2 (en) 2017-04-11 2021-02-02 Ecole Polytechnique Federale De Lausanne (Epfl) Tip connector for fluidic and electrical connection
US10739295B2 (en) * 2017-04-28 2020-08-11 Taiwan Semiconductor Manufacturing Co., Ltd. Integrated reference electrode and fluid dispenser
US11583847B2 (en) 2017-11-30 2023-02-21 Corning Incorporated Pipette with encapsulated or integral filter, and method and apparatus for forming same
US12216083B2 (en) 2018-12-27 2025-02-04 Shimadzu Corporation Method for detecting presence/absence of liquid suctioned by syringe pump, and device with syringe pump
US11331660B2 (en) 2019-01-04 2022-05-17 Funai Electric Co. Ltd. Digital dispense system
US20200217764A1 (en) * 2019-01-04 2020-07-09 Funai Electric Co., Ltd. Digital dispense system
US11768215B2 (en) 2019-01-04 2023-09-26 Funai Electric Co., Ltd. Digital dispense system cartridge
US11474007B2 (en) 2019-01-04 2022-10-18 Funai Electric Co., Ltd. Digital dispense system
US20240085443A1 (en) * 2021-01-20 2024-03-14 Enplas Corporation Liquid handling device, liquid handling system, and liquid handling method

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2656508A (en) 1949-08-27 1953-10-20 Wallace H Coulter Means for counting particles suspended in a fluid
US3910702A (en) * 1974-02-12 1975-10-07 Particle Technology Inc Apparatus for detecting particles employing apertured light emitting device
US4130754A (en) * 1977-06-16 1978-12-19 Cortex Research Corporation Particle counting
US4164870A (en) * 1978-04-10 1979-08-21 Medical Laboratory Automation, Inc. Pipettes
US4488814A (en) * 1981-09-28 1984-12-18 Miles Laboratories, Inc. Apparatus for and method of optical absorbance and fluorescent radiation measurement
US4873875A (en) * 1986-06-27 1989-10-17 Prism Technology, Inc. System for optically interrogating liquid samples and for withdrawing selected sample portions
JPS6396457U (enExample) * 1986-12-13 1988-06-22
AT391634B (de) * 1988-05-04 1990-11-12 Avl Verbrennungskraft Messtech Analysengeraet
US5376878A (en) 1991-12-12 1994-12-27 Fisher; Timothy C. Multiple-aperture particle counting sizing and deformability-measuring apparatus
US5516564A (en) * 1993-04-28 1996-05-14 Costar Corporation Sterile irradiated hydrophobic pipette tip
DE4427725C2 (de) * 1994-08-05 1996-10-24 Inst Chemo Biosensorik Meßeinrichtung zur Analyse von Flüssigkeiten
US6454945B1 (en) 1995-06-16 2002-09-24 University Of Washington Microfabricated devices and methods
US5695092A (en) * 1996-01-03 1997-12-09 Betzdearborn Inc. Fluid flow measuring system
DE69839709D1 (de) * 1997-12-24 2008-08-21 Cepheid Vorrichtung und Verfahren zur Lyse
CA2229528A1 (en) 1998-02-13 1999-08-13 Shailesh Mehta Apparatus and method for analyzing particles
FR2777086B3 (fr) * 1998-04-01 2000-06-09 Bio Merieux Procede de prelevement et de detection de surface d'un echantillon biologique par l'intermediaire d'un appareil d'aspiration-refoulement
EP1046032A4 (en) * 1998-05-18 2002-05-29 Univ Washington LIQUID ANALYSIS CARTRIDGE
US6169394B1 (en) 1998-09-18 2001-01-02 University Of The Utah Research Foundation Electrical detector for micro-analysis systems
US6285807B1 (en) * 1998-11-16 2001-09-04 Trustees Of Tufts College Fiber optic sensor for long-term analyte measurements in fluids
EP1054250B1 (en) * 1999-01-25 2002-09-04 Hamamatsu Photonics K.K. Pipette adaptor, pipette for absorbance measurement, method and apparatus for absorbance measurement
DE19933458B4 (de) * 1999-07-15 2015-08-20 Eppendorf Ag Einrichtungen und Systeme zum Handhaben von Flüssigkeitsproben
US6437551B1 (en) 1999-11-02 2002-08-20 The Regents Of The University Of California Microfabricated AC impedance sensor
JP2001183382A (ja) * 1999-12-28 2001-07-06 Roche Diagnostics Gmbh 分注機の動作確認装置および確認方法
JP2001221824A (ja) * 2000-02-10 2001-08-17 Oht Inc 検査装置及び検査方法、検査ユニット
AU2001245365B8 (en) * 2000-02-29 2005-11-03 Gen-Probe Incorporated Fluid dispense and liquid surface verification system and method
JP2001242185A (ja) * 2000-02-29 2001-09-07 Hitachi Ltd 分注装置、及び、これに用いるノズルチップ
AU2001249176A1 (en) 2000-03-14 2001-09-24 Micronics, Inc. Microfluidic analysis cartridge
US6370942B1 (en) * 2000-05-15 2002-04-16 Dade Behring Inc. Method for verifying the integrity of a fluid transfer
US6382228B1 (en) * 2000-08-02 2002-05-07 Honeywell International Inc. Fluid driving system for flow cytometry
US20020086431A1 (en) * 2000-08-21 2002-07-04 Markham Walter Bruce Sample preparation and slide plating apparatus and method
DE10052819B4 (de) * 2000-10-24 2004-02-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Pipettensystem und Pipettenarray sowie Verfahren zum Befüllen eines Pipettensystems
WO2002060582A2 (en) * 2000-11-16 2002-08-08 Fluidigm Corporation Microfluidic devices for introducing and dispensing fluids from microfluidic systems
US6461808B1 (en) * 2001-06-12 2002-10-08 Signature Bioscience, Inc. Pipette-loaded bioassay assembly for detecting molecular or cellular events
JP2005528081A (ja) * 2001-11-30 2005-09-22 ブリストル−マイヤーズ スクイブ カンパニー 細胞電気特性計測用のピペット形態及びそのアレイ
US6703819B2 (en) * 2001-12-03 2004-03-09 Board Of Regents, The University Of Texas System Particle impedance sensor
US7223371B2 (en) * 2002-03-14 2007-05-29 Micronics, Inc. Microfluidic channel network device
US20030180965A1 (en) * 2002-03-25 2003-09-25 Levent Yobas Micro-fluidic device and method of manufacturing and using the same
US6794877B2 (en) 2002-07-31 2004-09-21 International Technidyne Corporation Apparatus and method for analytical determinations
EP1420255B1 (en) * 2002-11-18 2007-10-17 Sysmex Corporation Sample analyzer and its components
US7338637B2 (en) * 2003-01-31 2008-03-04 Hewlett-Packard Development Company, L.P. Microfluidic device with thin-film electronic devices
US7682833B2 (en) * 2003-09-10 2010-03-23 Abbott Point Of Care Inc. Immunoassay device with improved sample closure
US20050118705A1 (en) * 2003-11-07 2005-06-02 Rabbitt Richard D. Electrical detectors for microanalysis
WO2005121780A2 (en) 2003-12-09 2005-12-22 Board Of Regents, The University Of Texas System Methods and apparatus for characterizing, measuring, and dispensing fluids
FI20040292A0 (fi) * 2004-02-25 2004-02-25 Thermo Electron Oy Kalibroitava pipetti
EP1643254A3 (en) * 2004-10-04 2006-09-13 Fuji Photo Film Co., Ltd. Sample supplying method and device
US8171778B2 (en) * 2006-05-05 2012-05-08 E I Spectra, LLC Thin film particle sensor

Also Published As

Publication number Publication date
CN102316988B (zh) 2014-02-19
EP2195114A1 (en) 2010-06-16
CN102316988A (zh) 2012-01-11
ES2624930T3 (es) 2017-07-18
EP2195114A4 (en) 2011-08-31
EP2195114B1 (en) 2017-03-22
US20100199788A1 (en) 2010-08-12
JP2010540226A (ja) 2010-12-24
US8015887B2 (en) 2011-09-13
WO2009045343A1 (en) 2009-04-09

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