ES2624930T3 - Punta de pipeta instrumentada - Google Patents
Punta de pipeta instrumentada Download PDFInfo
- Publication number
- ES2624930T3 ES2624930T3 ES08835264.6T ES08835264T ES2624930T3 ES 2624930 T3 ES2624930 T3 ES 2624930T3 ES 08835264 T ES08835264 T ES 08835264T ES 2624930 T3 ES2624930 T3 ES 2624930T3
- Authority
- ES
- Spain
- Prior art keywords
- fluid
- pipette tip
- fluid path
- pipette
- trace
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000012530 fluid Substances 0.000 claims abstract description 134
- 239000002245 particle Substances 0.000 claims description 19
- 239000000523 sample Substances 0.000 description 34
- 239000000758 substrate Substances 0.000 description 24
- 239000011573 trace mineral Substances 0.000 description 24
- 235000013619 trace mineral Nutrition 0.000 description 24
- 238000001514 detection method Methods 0.000 description 11
- 238000004891 communication Methods 0.000 description 10
- 238000000034 method Methods 0.000 description 10
- 210000004027 cell Anatomy 0.000 description 9
- 238000004458 analytical method Methods 0.000 description 8
- 239000000976 ink Substances 0.000 description 8
- 238000012360 testing method Methods 0.000 description 7
- 239000007788 liquid Substances 0.000 description 5
- 230000008878 coupling Effects 0.000 description 4
- 238000010168 coupling process Methods 0.000 description 4
- 238000005859 coupling reaction Methods 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 3
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- 239000003792 electrolyte Substances 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 229920000728 polyester Polymers 0.000 description 3
- 229920006267 polyester film Polymers 0.000 description 3
- 238000007639 printing Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 239000004020 conductor Substances 0.000 description 2
- 238000000151 deposition Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000010408 film Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 238000007650 screen-printing Methods 0.000 description 2
- 229910052709 silver Inorganic materials 0.000 description 2
- 239000004332 silver Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 230000036962 time dependent Effects 0.000 description 2
- 229920002799 BoPET Polymers 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 244000261422 Lysimachia clethroides Species 0.000 description 1
- 239000005041 Mylar™ Substances 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 229910021607 Silver chloride Inorganic materials 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 230000003833 cell viability Effects 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000011651 chromium Substances 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000004070 electrodeposition Methods 0.000 description 1
- 238000009713 electroplating Methods 0.000 description 1
- 229920002457 flexible plastic Polymers 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000000873 masking effect Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910001092 metal group alloy Inorganic materials 0.000 description 1
- 238000005459 micromachining Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 238000011192 particle characterization Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920003223 poly(pyromellitimide-1,4-diphenyl ether) Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0275—Interchangeable or disposable dispensing tips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1048—General features of the devices using the transfer device for another function
- G01N2035/1062—General features of the devices using the transfer device for another function for testing the liquid while it is in the transfer device
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99575207P | 2007-09-29 | 2007-09-29 | |
| US995752P | 2007-09-29 | ||
| PCT/US2008/011205 WO2009045343A1 (en) | 2007-09-29 | 2008-09-26 | Instrumented pipette tip |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2624930T3 true ES2624930T3 (es) | 2017-07-18 |
Family
ID=40526505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES08835264.6T Active ES2624930T3 (es) | 2007-09-29 | 2008-09-26 | Punta de pipeta instrumentada |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8015887B2 (enExample) |
| EP (1) | EP2195114B1 (enExample) |
| JP (1) | JP5658566B2 (enExample) |
| CN (1) | CN102316988B (enExample) |
| ES (1) | ES2624930T3 (enExample) |
| WO (1) | WO2009045343A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009070246A1 (en) * | 2007-11-27 | 2009-06-04 | E.I Spectra, Llc | Fluorescence-based pipette instrument |
| SG175303A1 (en) | 2009-04-27 | 2011-11-28 | Ei Spectra Llc | Pipette instrument |
| US8602644B2 (en) * | 2009-05-08 | 2013-12-10 | University Of North Texas | Multifunctional micropipette biological sensor |
| AU2010295250A1 (en) * | 2009-09-18 | 2012-04-05 | Minifab (Australia) Pty Ltd | Instrumented pipette |
| DE102009049783A1 (de) * | 2009-10-19 | 2011-04-21 | Eppendorf Ag | Elektrisch leitfähige Pipettenspitze |
| US20120019270A1 (en) * | 2010-07-21 | 2012-01-26 | Amodei Dario G | Microfabricated pipette and method of manufacture |
| US20130035660A1 (en) | 2011-08-01 | 2013-02-07 | Alcyone Lifesciences, Inc. | Multidirectional microfluidic drug delivery devices with conformable balloons |
| DK2809782T3 (da) | 2012-01-31 | 2017-11-20 | The Rogosin Inst Inc | Forbedret fremgangsmåde til fremstilling af makrokugler |
| US9333502B1 (en) | 2012-09-13 | 2016-05-10 | E. I. Spectra, Llc | Sample-acquiring microfluidic tester |
| EP2934627B1 (en) | 2012-12-18 | 2021-04-07 | Alcyone Lifesciences, Inc. | Devices and methods for reducing or preventing backflow in a delivery system |
| CN110215595B (zh) | 2013-06-17 | 2022-04-12 | 亚克安娜治疗学有限公司 | 导管末梢保护系统和立体定向固定装置 |
| ES2738298T3 (es) | 2013-07-31 | 2020-01-21 | Alcyone Lifesciences Inc | Sistemas y métodos de suministro de fármacos, tratamiento y monitoreo |
| EP3058337B1 (en) | 2013-10-15 | 2019-02-20 | Ecole Polytechnique Federale de Lausanne (EPFL) | Sensing tip with electrical impedance sensor |
| US10806396B2 (en) | 2015-01-26 | 2020-10-20 | Alcyone Lifesciences, Inc. | Drug delivery methods with tracer |
| DE102015214566A1 (de) * | 2015-07-30 | 2017-02-02 | Hamilton Bonaduz Ag | Pipettiervorrichtung zur Pipettierung kleiner Flüssigkeitsvolumina |
| WO2017120167A1 (en) | 2016-01-04 | 2017-07-13 | Alcyone Lifesciences, Inc. | Methods and devices for treating stroke |
| DE102016201181B3 (de) * | 2016-01-27 | 2017-05-04 | Albert-Ludwigs-Universität Freiburg | Röhre mit einer mikrofluidischen Struktur |
| JP6842242B2 (ja) * | 2016-03-22 | 2021-03-17 | 株式会社アイカムス・ラボ | 分注システム |
| US10480979B2 (en) * | 2016-05-25 | 2019-11-19 | Agilent Technologies, Inc. | Flow meters, flow meter cartridges, and related methods |
| PL3335795T3 (pl) * | 2016-12-16 | 2019-09-30 | Eppendorf Ag | Sposób dozowania cieczy za pomocą pipety i strzykawki oraz pipeta do uruchamiania strzykawki do dozowania cieczy |
| US10910749B2 (en) | 2017-04-11 | 2021-02-02 | Ecole Polytechnique Federale De Lausanne (Epfl) | Tip connector for fluidic and electrical connection |
| US10739295B2 (en) * | 2017-04-28 | 2020-08-11 | Taiwan Semiconductor Manufacturing Co., Ltd. | Integrated reference electrode and fluid dispenser |
| US11583847B2 (en) | 2017-11-30 | 2023-02-21 | Corning Incorporated | Pipette with encapsulated or integral filter, and method and apparatus for forming same |
| US12216083B2 (en) | 2018-12-27 | 2025-02-04 | Shimadzu Corporation | Method for detecting presence/absence of liquid suctioned by syringe pump, and device with syringe pump |
| US11331660B2 (en) | 2019-01-04 | 2022-05-17 | Funai Electric Co. Ltd. | Digital dispense system |
| US20200217764A1 (en) * | 2019-01-04 | 2020-07-09 | Funai Electric Co., Ltd. | Digital dispense system |
| US11768215B2 (en) | 2019-01-04 | 2023-09-26 | Funai Electric Co., Ltd. | Digital dispense system cartridge |
| US11474007B2 (en) | 2019-01-04 | 2022-10-18 | Funai Electric Co., Ltd. | Digital dispense system |
| US20240085443A1 (en) * | 2021-01-20 | 2024-03-14 | Enplas Corporation | Liquid handling device, liquid handling system, and liquid handling method |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2656508A (en) | 1949-08-27 | 1953-10-20 | Wallace H Coulter | Means for counting particles suspended in a fluid |
| US3910702A (en) * | 1974-02-12 | 1975-10-07 | Particle Technology Inc | Apparatus for detecting particles employing apertured light emitting device |
| US4130754A (en) * | 1977-06-16 | 1978-12-19 | Cortex Research Corporation | Particle counting |
| US4164870A (en) * | 1978-04-10 | 1979-08-21 | Medical Laboratory Automation, Inc. | Pipettes |
| US4488814A (en) * | 1981-09-28 | 1984-12-18 | Miles Laboratories, Inc. | Apparatus for and method of optical absorbance and fluorescent radiation measurement |
| US4873875A (en) * | 1986-06-27 | 1989-10-17 | Prism Technology, Inc. | System for optically interrogating liquid samples and for withdrawing selected sample portions |
| JPS6396457U (enExample) * | 1986-12-13 | 1988-06-22 | ||
| AT391634B (de) * | 1988-05-04 | 1990-11-12 | Avl Verbrennungskraft Messtech | Analysengeraet |
| US5376878A (en) | 1991-12-12 | 1994-12-27 | Fisher; Timothy C. | Multiple-aperture particle counting sizing and deformability-measuring apparatus |
| US5516564A (en) * | 1993-04-28 | 1996-05-14 | Costar Corporation | Sterile irradiated hydrophobic pipette tip |
| DE4427725C2 (de) * | 1994-08-05 | 1996-10-24 | Inst Chemo Biosensorik | Meßeinrichtung zur Analyse von Flüssigkeiten |
| US6454945B1 (en) | 1995-06-16 | 2002-09-24 | University Of Washington | Microfabricated devices and methods |
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| DE69839709D1 (de) * | 1997-12-24 | 2008-08-21 | Cepheid | Vorrichtung und Verfahren zur Lyse |
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| FR2777086B3 (fr) * | 1998-04-01 | 2000-06-09 | Bio Merieux | Procede de prelevement et de detection de surface d'un echantillon biologique par l'intermediaire d'un appareil d'aspiration-refoulement |
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| US6169394B1 (en) | 1998-09-18 | 2001-01-02 | University Of The Utah Research Foundation | Electrical detector for micro-analysis systems |
| US6285807B1 (en) * | 1998-11-16 | 2001-09-04 | Trustees Of Tufts College | Fiber optic sensor for long-term analyte measurements in fluids |
| EP1054250B1 (en) * | 1999-01-25 | 2002-09-04 | Hamamatsu Photonics K.K. | Pipette adaptor, pipette for absorbance measurement, method and apparatus for absorbance measurement |
| DE19933458B4 (de) * | 1999-07-15 | 2015-08-20 | Eppendorf Ag | Einrichtungen und Systeme zum Handhaben von Flüssigkeitsproben |
| US6437551B1 (en) | 1999-11-02 | 2002-08-20 | The Regents Of The University Of California | Microfabricated AC impedance sensor |
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| AU2001245365B8 (en) * | 2000-02-29 | 2005-11-03 | Gen-Probe Incorporated | Fluid dispense and liquid surface verification system and method |
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| EP1420255B1 (en) * | 2002-11-18 | 2007-10-17 | Sysmex Corporation | Sample analyzer and its components |
| US7338637B2 (en) * | 2003-01-31 | 2008-03-04 | Hewlett-Packard Development Company, L.P. | Microfluidic device with thin-film electronic devices |
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| WO2005121780A2 (en) | 2003-12-09 | 2005-12-22 | Board Of Regents, The University Of Texas System | Methods and apparatus for characterizing, measuring, and dispensing fluids |
| FI20040292A0 (fi) * | 2004-02-25 | 2004-02-25 | Thermo Electron Oy | Kalibroitava pipetti |
| EP1643254A3 (en) * | 2004-10-04 | 2006-09-13 | Fuji Photo Film Co., Ltd. | Sample supplying method and device |
| US8171778B2 (en) * | 2006-05-05 | 2012-05-08 | E I Spectra, LLC | Thin film particle sensor |
-
2008
- 2008-09-26 ES ES08835264.6T patent/ES2624930T3/es active Active
- 2008-09-26 JP JP2010526963A patent/JP5658566B2/ja active Active
- 2008-09-26 EP EP08835264.6A patent/EP2195114B1/en active Active
- 2008-09-26 WO PCT/US2008/011205 patent/WO2009045343A1/en not_active Ceased
- 2008-09-26 US US12/679,548 patent/US8015887B2/en active Active
- 2008-09-26 CN CN200880109435.2A patent/CN102316988B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP5658566B2 (ja) | 2015-01-28 |
| CN102316988B (zh) | 2014-02-19 |
| EP2195114A1 (en) | 2010-06-16 |
| CN102316988A (zh) | 2012-01-11 |
| EP2195114A4 (en) | 2011-08-31 |
| EP2195114B1 (en) | 2017-03-22 |
| US20100199788A1 (en) | 2010-08-12 |
| JP2010540226A (ja) | 2010-12-24 |
| US8015887B2 (en) | 2011-09-13 |
| WO2009045343A1 (en) | 2009-04-09 |
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