JP5657394B2 - 疼痛の治療又は予防方法 - Google Patents

疼痛の治療又は予防方法 Download PDF

Info

Publication number
JP5657394B2
JP5657394B2 JP2010549209A JP2010549209A JP5657394B2 JP 5657394 B2 JP5657394 B2 JP 5657394B2 JP 2010549209 A JP2010549209 A JP 2010549209A JP 2010549209 A JP2010549209 A JP 2010549209A JP 5657394 B2 JP5657394 B2 JP 5657394B2
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
compounds
compound
pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2010549209A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011513377A5 (enExample
JP2011513377A (ja
Inventor
エリアフ カプラン
エリアフ カプラン
Original Assignee
ノヴァレメッド リミテッド
ノヴァレメッド リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノヴァレメッド リミテッド, ノヴァレメッド リミテッド filed Critical ノヴァレメッド リミテッド
Publication of JP2011513377A publication Critical patent/JP2011513377A/ja
Publication of JP2011513377A5 publication Critical patent/JP2011513377A5/ja
Application granted granted Critical
Publication of JP5657394B2 publication Critical patent/JP5657394B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/90Carboxylic acid amides having nitrogen atoms of carboxamide groups further acylated
    • C07C233/91Carboxylic acid amides having nitrogen atoms of carboxamide groups further acylated with carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/003Compounds containing elements of Groups 2 or 12 of the Periodic Table without C-Metal linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyethers (AREA)
JP2010549209A 2008-03-06 2009-03-06 疼痛の治療又は予防方法 Expired - Fee Related JP5657394B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0804213.7 2008-03-06
GBGB0804213.7A GB0804213D0 (en) 2008-03-06 2008-03-06 A method of printing or preventing pain
PCT/IB2009/000448 WO2009109850A2 (en) 2008-03-06 2009-03-06 A method of treating or preventing pain

Publications (3)

Publication Number Publication Date
JP2011513377A JP2011513377A (ja) 2011-04-28
JP2011513377A5 JP2011513377A5 (enExample) 2013-04-11
JP5657394B2 true JP5657394B2 (ja) 2015-01-21

Family

ID=39327664

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010549209A Expired - Fee Related JP5657394B2 (ja) 2008-03-06 2009-03-06 疼痛の治療又は予防方法

Country Status (12)

Country Link
US (2) US8883853B2 (enExample)
EP (1) EP2323644B1 (enExample)
JP (1) JP5657394B2 (enExample)
AU (1) AU2009220931B2 (enExample)
CA (1) CA2717692C (enExample)
DK (1) DK2323644T3 (enExample)
ES (1) ES2505325T3 (enExample)
GB (1) GB0804213D0 (enExample)
IL (1) IL207965A (enExample)
PL (1) PL2323644T3 (enExample)
PT (1) PT2323644E (enExample)
WO (1) WO2009109850A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013504555A (ja) * 2009-09-09 2013-02-07 ノヴァレメッド リミテッド 疼痛の治療又は予防方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4939396B2 (ja) 2004-03-26 2012-05-23 ノヴァレメッド リミテッド Aids及び他のウイルス性疾患及びhiv関連感染症の改善又はその治療用化合物及びそのような化合物を含む組成物、そのような疾患及び感染症の治療方法及びそのような化合物及び組成物の製造方法
GB0804213D0 (en) 2008-03-06 2008-04-16 New Era Biotech Ltd A method of printing or preventing pain
US8802734B2 (en) 2009-09-09 2014-08-12 Novaremed Limited Method of treating or preventing pain
GB201116335D0 (en) * 2011-09-21 2011-11-02 Novaremed Ltd A method of treating or preventing affective disorders
AU2012348529B2 (en) * 2011-12-08 2017-03-30 Novaremed Ltd. Isolated stereoisomeric forms of (S) 2-N (3-O-(propan 2-ol) -1-propyl-4-hydroxybenzene) -3-phenylpropylamide
SG11202111773QA (en) 2019-01-23 2021-11-29 Novaremed Ltd Compounds for use in the treatment or prophylaxis of pain, inflammation and/or autoimmunity
EP3939578A1 (en) 2020-07-13 2022-01-19 Novaremed Ltd. Compounds for treatment or prevention of an infection resulting from a coronavirus and/or a coronavirus-induced disease

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2908691A (en) * 1958-07-14 1959-10-13 Searle & Co Hydroxyphenalkylaminoalkylindoles and ethers corresponding thereto
GB1037655A (en) * 1964-05-20 1966-08-03 Koninklijke Pharma Fab Nv Di(aralkyl)amines
ZA732136B (en) 1972-04-12 1974-03-27 Lilly Co Eli Dopamine derivatives
JPS5236606A (en) 1975-09-12 1977-03-22 Tanabe Seiyaku Co Ltd Process for preparation of amino compounds
US4766106A (en) * 1985-06-26 1988-08-23 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polymer conjugation
US4908322A (en) * 1985-09-06 1990-03-13 The United States Of America As Represented By The Department Of Health And Human Services Derivatization of amines for electrochemical detection
US5696270A (en) * 1989-05-23 1997-12-09 Abbott Laboratories Intermediate for making retroviral protease inhibiting compounds
IS2334B (is) * 1992-09-08 2008-02-15 Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) Aspartyl próteasi hemjari af nýjum flokki súlfonamíða
JP2848232B2 (ja) 1993-02-19 1999-01-20 武田薬品工業株式会社 アルデヒド誘導体
AU1463997A (en) * 1995-12-22 1997-07-17 Acea Pharmaceuticals, Inc. Subtype-selective nmda receptor ligands and the use thereof
WO1997029079A1 (en) 1996-02-06 1997-08-14 Japan Tobacco Inc. Novel compounds and pharmaceutical use thereof
JP2941230B2 (ja) * 1997-05-06 1999-08-25 コナミ株式会社 画像表示処理装置,画像表示処理方法,及びコンピュータプログラムを記録した機械読取り可能な記録媒体
AU2002224139A1 (en) 2000-12-05 2002-06-18 Nippon Chemiphar Co. Ltd. Ppar (peroxisome proliferator activated receptor) activators
JP4667870B2 (ja) * 2002-10-03 2011-04-13 ノヴァレメッド リミテッド 自己免疫疾患、免疫−アレルギー疾患及び臓器又は組織移植拒絶反応の治療において使用する新規な化合物
WO2004047743A2 (en) * 2002-11-22 2004-06-10 Bristol-Myers Squibb Company 1-aryl-2-hydroxyethyl amides as potassium channel openers
JP4939396B2 (ja) * 2004-03-26 2012-05-23 ノヴァレメッド リミテッド Aids及び他のウイルス性疾患及びhiv関連感染症の改善又はその治療用化合物及びそのような化合物を含む組成物、そのような疾患及び感染症の治療方法及びそのような化合物及び組成物の製造方法
DE102004039373A1 (de) * 2004-08-12 2006-02-23 Grünenthal GmbH Para-Alkyl-substituierte N-(4-Hydroxy-3-methoxy-benzyl)-zimtsäureamide und deren Verwendung zur Herstellung von Arzneimitteln
RU2309144C2 (ru) * 2005-03-25 2007-10-27 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Фенилсодержащие n-ацильные производные аминов, способ их получения, фармацевтическая композиция и их применение в качестве противовоспалительных и анальгетических средств
PL2026775T3 (pl) 2006-05-09 2015-12-31 Novaremed Ltd Zastosowanie inhibitorów kinazy tyrozynowej Syk w leczeniu komórkowych zaburzeń proliferacyjnych
WO2009039218A2 (en) 2007-09-17 2009-03-26 Chi-Huey Wong Compositions and methods for treating inflammation and inflammation-related disorders by plectranthus amboinicus extracts
GB0804213D0 (en) 2008-03-06 2008-04-16 New Era Biotech Ltd A method of printing or preventing pain
CN101503370B (zh) 2009-03-02 2012-08-22 上海应用技术学院 一种n-环丙基-反-2-顺-6-壬二烯酸酰胺的合成方法
CN101503373B (zh) 2009-03-13 2013-07-24 山东大学 2-氨基-1-(4-硝基苯基)-1-乙醇类金属蛋白酶抑制剂及其制备方法和用途
US8802734B2 (en) * 2009-09-09 2014-08-12 Novaremed Limited Method of treating or preventing pain

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013504555A (ja) * 2009-09-09 2013-02-07 ノヴァレメッド リミテッド 疼痛の治療又は予防方法

Also Published As

Publication number Publication date
US8883853B2 (en) 2014-11-11
AU2009220931A1 (en) 2009-09-11
EP2323644A2 (en) 2011-05-25
PL2323644T3 (pl) 2014-10-31
IL207965A0 (en) 2010-12-30
AU2009220931B2 (en) 2014-11-13
WO2009109850A2 (en) 2009-09-11
GB0804213D0 (en) 2008-04-16
CA2717692A1 (en) 2009-09-11
PT2323644E (pt) 2014-07-25
DK2323644T3 (da) 2014-07-21
US20110039936A1 (en) 2011-02-17
WO2009109850A3 (en) 2009-12-10
CA2717692C (en) 2016-06-07
US9199917B2 (en) 2015-12-01
JP2011513377A (ja) 2011-04-28
IL207965A (en) 2015-10-29
EP2323644B1 (en) 2014-04-23
ES2505325T3 (es) 2014-10-09
US20150080473A1 (en) 2015-03-19

Similar Documents

Publication Publication Date Title
JP5657394B2 (ja) 疼痛の治療又は予防方法
KR101677126B1 (ko) 탄산염 프로드러그 및 그것의 사용 방법
KR101698028B1 (ko) 수용성 아세트아미노펜 유사체
AU2002305816B2 (en) Sustained-release analgesic compounds
KR101589846B1 (ko) 히드로모르폰의 벤조산, 벤조산 유도체 및 헤테로아릴 카르복실산 컨쥬게이트, 전구약물, 이의 제조 방법 및 용도
AU2002305816A1 (en) Sustained-release analgesic compounds
AU2006241176A1 (en) TRPV1 agonist compounds and methods for making and using the same
JP6016179B2 (ja) 疼痛の治療又は予防用医薬組成物
US20160317479A1 (en) Method of treating or preventing pain
CN100356913C (zh) 左旋(r)班布特罗及其药物用途
ES2983998T3 (es) Compuesto de indol para tratar la cistitis intersticial
US11891350B2 (en) Compounds for use in the treatment or prophylaxis of pain, inflammation and/or autoimmunity
HK1179523B (en) N-substituted benzenepropanamide or benzenepropenamide for use in the treatment of pain and inflammation
WO2005016331A1 (ja) N−(ベンゾイル)アミノ酸誘導体を有効成分とするニューロパシー性疼痛治療剤
HK40061961B (en) Compounds for use in the treatment or prophylaxis of pain, inflammation and/or autoimmunity
HK40061961A (en) Compounds for use in the treatment or prophylaxis of pain, inflammation and/or autoimmunity
WO2015128697A1 (en) Novel compounds having anti-allodynic and antihyperalgesic activity

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120306

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20120306

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130219

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20131010

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20140205

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20140213

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140507

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20141027

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20141126

R150 Certificate of patent or registration of utility model

Ref document number: 5657394

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees