JP5650639B2 - 腫瘍疾患の治療 - Google Patents
腫瘍疾患の治療 Download PDFInfo
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- JP5650639B2 JP5650639B2 JP2011503304A JP2011503304A JP5650639B2 JP 5650639 B2 JP5650639 B2 JP 5650639B2 JP 2011503304 A JP2011503304 A JP 2011503304A JP 2011503304 A JP2011503304 A JP 2011503304A JP 5650639 B2 JP5650639 B2 JP 5650639B2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4813—Exopeptidases (3.4.11. to 3.4.19)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/17—Metallocarboxypeptidases (3.4.17)
- C12Y304/17023—Angiotensin-converting enzyme 2 (3.4.17.23)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ATA566/2008 | 2008-04-09 | ||
| AT0056608A AT506632A1 (de) | 2008-04-09 | 2008-04-09 | Behandlung von tumorerkrankungen |
| PCT/AT2009/000136 WO2009124330A2 (de) | 2008-04-09 | 2009-04-07 | Behandlung von tumorerkrankungen |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011516501A JP2011516501A (ja) | 2011-05-26 |
| JP2011516501A5 JP2011516501A5 (enExample) | 2012-05-31 |
| JP5650639B2 true JP5650639B2 (ja) | 2015-01-07 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011503304A Active JP5650639B2 (ja) | 2008-04-09 | 2009-04-07 | 腫瘍疾患の治療 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8946162B2 (enExample) |
| EP (2) | EP2274005B1 (enExample) |
| JP (1) | JP5650639B2 (enExample) |
| AT (1) | AT506632A1 (enExample) |
| AU (1) | AU2009235931B2 (enExample) |
| CA (1) | CA2720616C (enExample) |
| DK (1) | DK2274005T3 (enExample) |
| ES (1) | ES2425308T3 (enExample) |
| NZ (1) | NZ588435A (enExample) |
| PL (1) | PL2274005T3 (enExample) |
| PT (1) | PT2274005E (enExample) |
| WO (1) | WO2009124330A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT505262A1 (de) * | 2007-06-12 | 2008-12-15 | Apeiron Biolog Forschungs Und | Rekombinantes ace2 polypeptid |
| PL2859343T3 (pl) * | 2012-06-06 | 2020-05-18 | Attoquant Diagnostics Gmbh | Sposób pomiaru peptydowych produktów degradacji kaskady proteolitycznej w próbkach krwi |
| US8557958B1 (en) | 2012-06-18 | 2013-10-15 | Tarix Pharmaceuticals Ltd. | Compositions and methods for treatment of diabetes |
| US8633158B1 (en) | 2012-10-02 | 2014-01-21 | Tarix Pharmaceuticals Ltd. | Angiotensin in treating brain conditions |
| EP2943216B1 (en) * | 2013-01-14 | 2019-05-01 | Apeiron Biologics AG | Modified ace2 polypeptides |
| US9839668B2 (en) * | 2013-12-11 | 2017-12-12 | Attoquant Diagnostics Gmbh | Compositions and methods for the treatment of diseases related to the renin-angiotensin-system |
| US9333233B2 (en) | 2014-02-25 | 2016-05-10 | Tarix Pharmaceuticals Ltd. | Methods and compositions for the delayed treatment of stroke |
| US20200188473A1 (en) * | 2017-05-02 | 2020-06-18 | Beth Israel Deaconess Medical Center, Inc. | Combination therapy for cancer |
| US11337909B2 (en) | 2017-11-29 | 2022-05-24 | Max-Delbrück-Centrum Für Molekulare Medizin In Der Helmholtz-Gemeinschaft | Methods for modulating pigmentation by angiotensin-converting enzyme 2 modulation |
| WO2021190980A1 (en) | 2020-03-22 | 2021-09-30 | Quadrucept Bio Limited | Multimers for viral strain evolution |
| WO2021202912A1 (en) * | 2020-04-01 | 2021-10-07 | Washington University | Compositions for treatment of viral respiratory infections and methods of use thereof |
| CN112626099A (zh) * | 2020-09-29 | 2021-04-09 | 清华大学 | 使用原核细胞发酵表达血管紧张素转化酶2的方法 |
| WO2022184659A1 (en) | 2021-03-01 | 2022-09-09 | Quadrucept Bio Limited | Antibody domains & multimers |
| US20250009853A1 (en) | 2021-12-03 | 2025-01-09 | Wisconsin Alumni Research Foundation | Mutant ace2 proteins and methods of using same |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6989363B1 (en) | 1997-12-11 | 2006-01-24 | Millennium Pharmaceuticals, Inc. | Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor |
| US6610497B1 (en) | 1997-12-11 | 2003-08-26 | Millennium Pharmaceuticals, Inc. | Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor |
| US6194556B1 (en) | 1997-12-11 | 2001-02-27 | Millennium Pharmaceuticals, Inc. | Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therfor |
| US7375073B2 (en) * | 2002-02-27 | 2008-05-20 | Wake Forest University Health Sciences | Angiotensin-(1-7) and angiotensin-(1-7) agonists for inhibition of cancer cell growth |
| ES2318137T3 (es) | 2002-06-19 | 2009-05-01 | University Health Network | Activacion de ace2 para el tratamiento de enfermedades cardiacas, pulmonares y renales e hipertension. |
| EP1374907A3 (en) | 2002-06-24 | 2004-01-07 | Ghanem Elias c/o Institut Jules Bordet Ghanem | Drug transport and delivery system |
| EP1723962A1 (en) * | 2005-05-19 | 2006-11-22 | IMBA-Institut für Molekulare Biotechnologie GmbH | Use of inhibitors of the renin-angiotensin system for the treatment of lung injuries |
| AT505262A1 (de) * | 2007-06-12 | 2008-12-15 | Apeiron Biolog Forschungs Und | Rekombinantes ace2 polypeptid |
-
2008
- 2008-04-09 AT AT0056608A patent/AT506632A1/de not_active Application Discontinuation
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2009
- 2009-04-07 PL PL09730771T patent/PL2274005T3/pl unknown
- 2009-04-07 WO PCT/AT2009/000136 patent/WO2009124330A2/de not_active Ceased
- 2009-04-07 NZ NZ588435A patent/NZ588435A/xx unknown
- 2009-04-07 DK DK09730771.4T patent/DK2274005T3/da active
- 2009-04-07 AU AU2009235931A patent/AU2009235931B2/en active Active
- 2009-04-07 PT PT97307714T patent/PT2274005E/pt unknown
- 2009-04-07 CA CA2720616A patent/CA2720616C/en active Active
- 2009-04-07 JP JP2011503304A patent/JP5650639B2/ja active Active
- 2009-04-07 ES ES09730771T patent/ES2425308T3/es active Active
- 2009-04-07 EP EP09730771.4A patent/EP2274005B1/de active Active
- 2009-04-07 EP EP13162709.3A patent/EP2644203A1/de not_active Withdrawn
- 2009-04-07 US US12/937,029 patent/US8946162B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AT506632A1 (de) | 2009-10-15 |
| WO2009124330A2 (de) | 2009-10-15 |
| EP2644203A1 (de) | 2013-10-02 |
| CA2720616C (en) | 2016-08-09 |
| EP2274005A2 (de) | 2011-01-19 |
| US20110033524A1 (en) | 2011-02-10 |
| WO2009124330A3 (de) | 2009-12-10 |
| JP2011516501A (ja) | 2011-05-26 |
| US8946162B2 (en) | 2015-02-03 |
| EP2274005B1 (de) | 2013-05-29 |
| AU2009235931B2 (en) | 2015-07-23 |
| PL2274005T3 (pl) | 2013-12-31 |
| DK2274005T3 (da) | 2013-08-19 |
| AU2009235931A1 (en) | 2009-10-15 |
| CA2720616A1 (en) | 2009-10-15 |
| ES2425308T3 (es) | 2013-10-14 |
| NZ588435A (en) | 2012-10-26 |
| PT2274005E (pt) | 2013-08-27 |
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