JP5643514B2 - ポリシクロ染料およびその使用 - Google Patents
ポリシクロ染料およびその使用 Download PDFInfo
- Publication number
- JP5643514B2 JP5643514B2 JP2009549253A JP2009549253A JP5643514B2 JP 5643514 B2 JP5643514 B2 JP 5643514B2 JP 2009549253 A JP2009549253 A JP 2009549253A JP 2009549253 A JP2009549253 A JP 2009549253A JP 5643514 B2 JP5643514 B2 JP 5643514B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- fluorescent dye
- alkyl
- compound
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/0075—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of an heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/0008—Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain
- C09B23/0033—Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain the substituent being bound through a sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/0008—Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain
- C09B23/005—Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain the substituent being a COOH and/or a functional derivative thereof
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/0066—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of a carbocyclic ring,(e.g. benzene, naphtalene, cyclohexene, cyclobutenene-quadratic acid)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88906607P | 2007-02-09 | 2007-02-09 | |
| US60/889,066 | 2007-02-09 | ||
| PCT/US2008/053399 WO2008100817A2 (en) | 2007-02-09 | 2008-02-08 | Polycyclo dyes and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014071365A Division JP2014167119A (ja) | 2007-02-09 | 2014-03-31 | ポリシクロ染料およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010518236A JP2010518236A (ja) | 2010-05-27 |
| JP2010518236A5 JP2010518236A5 (enExample) | 2012-03-22 |
| JP5643514B2 true JP5643514B2 (ja) | 2014-12-17 |
Family
ID=39690741
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009549253A Active JP5643514B2 (ja) | 2007-02-09 | 2008-02-08 | ポリシクロ染料およびその使用 |
| JP2014071365A Withdrawn JP2014167119A (ja) | 2007-02-09 | 2014-03-31 | ポリシクロ染料およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014071365A Withdrawn JP2014167119A (ja) | 2007-02-09 | 2014-03-31 | ポリシクロ染料およびその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8221721B2 (enExample) |
| EP (1) | EP2118206B9 (enExample) |
| JP (2) | JP5643514B2 (enExample) |
| DK (1) | DK2118206T3 (enExample) |
| ES (1) | ES2670852T3 (enExample) |
| WO (1) | WO2008100817A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002038190A2 (en) * | 2000-10-27 | 2002-05-16 | Beth Israel Deaconess Medical Center | Non-isotopic detection of osteoblastic activity in vivo using modified bisphosphonates |
| ES2612738T3 (es) * | 2005-09-02 | 2017-05-18 | Visen Medical, Inc. | Agentes de formación de imágenes fluorescentes biocompatibles |
| WO2007028118A2 (en) | 2005-09-02 | 2007-03-08 | Visen Medical, Inc. | Nicotinic acid and picolinic acid derived near-infrared fluorophores |
| DK1934211T3 (en) | 2005-09-02 | 2017-04-10 | Visen Medical Inc | Biocompatible N, N-disubstituted sulfonamide-containing fluorescent color markers |
| US9913917B2 (en) | 2005-12-22 | 2018-03-13 | Visen Medical, Inc. | Biocompatible fluorescent metal oxide nanoparticles |
| JP5643514B2 (ja) | 2007-02-09 | 2014-12-17 | ビセン メディカル, インコーポレイテッド | ポリシクロ染料およびその使用 |
| WO2008109832A2 (en) * | 2007-03-08 | 2008-09-12 | Visen Medical, Inc. | Viable near-infrared fluorochrome labeled cells and methods of making and using same |
| EP2732826B1 (en) | 2008-01-18 | 2017-11-08 | Visen Medical, Inc. | Fluorescent imaging agents |
| SG10201706428XA (en) * | 2009-02-06 | 2017-09-28 | Beth Israel Deaconess Medical Ct Inc | Charge-balanced imaging agents |
| EP2707102B1 (en) | 2011-05-09 | 2019-11-13 | Visen Medical, Inc. | Carbonic anhydrase targeting agents and methods of using same |
| WO2013148319A1 (en) | 2012-03-30 | 2013-10-03 | Visen Medical, Inc. | Bacterial imaging agents and methods of using same |
| CA2882019C (en) | 2012-08-15 | 2021-02-09 | Visen Medical, Inc. | Prostate specific antigen agents and methods of using same for prostate cancer imaging |
| IL221489A0 (en) * | 2012-08-15 | 2012-12-31 | Aspect Imaging Ltd | Imaging system for generating a rendered image |
| US20140051973A1 (en) * | 2012-08-15 | 2014-02-20 | Aspect Imaging Ltd | Mri imaging system for generating a rendered image |
| US20140051975A1 (en) * | 2012-08-15 | 2014-02-20 | Aspect Imaging Ltd. | Multiple heterogeneous imaging systems for clinical and preclinical diagnosis |
| AU2014228504C1 (en) | 2013-03-15 | 2019-10-03 | Visen Medical, Inc. | Substituted silaxanthenium red to near-infrared fluorochromes for in vitro and in vivo imaging and detection |
| CN105339436B (zh) | 2013-03-15 | 2018-05-25 | 文森医学公司 | 4,4-二取代环己基桥连七甲川花菁染料及其应用 |
| EP3165153A1 (en) * | 2015-11-05 | 2017-05-10 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | System for fluorescence aided surgery |
| WO2019067180A1 (en) | 2017-09-29 | 2019-04-04 | Perkinelmer Health Sciences, Inc. | NIR-SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION |
| EA202092228A1 (ru) * | 2018-03-21 | 2021-07-19 | Эколь Политекник Федераль Де Лозанн (Эпфл) | Азацианиновые красители и их применение |
| US10633542B2 (en) | 2018-03-21 | 2020-04-28 | Ecole polytechnique fédérale de Lausanne (EPFL) | Azacyanine dyes and use thereof |
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| US4219335A (en) | 1978-09-18 | 1980-08-26 | E. I. Du Pont De Nemours And Company | Immunochemical testing using tagged reagents |
| US6086737A (en) | 1984-03-29 | 2000-07-11 | Li-Cor, Inc. | Sequencing near infrared and infrared fluorescence labeled DNA for detecting using laser diodes and suitable labels therefor |
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| JPH08501097A (ja) | 1992-09-04 | 1996-02-06 | ザ ゼネラル ホスピタル コーポレーション | 臨床診断及び治療用部分を含む生体適合性ポリマー |
| DE69434016T2 (de) | 1993-03-04 | 2005-02-10 | Fuji Photo Film Co., Ltd., Minami-Ashigara | Photographisches Silberhalogenidmaterial |
| JPH0862763A (ja) | 1994-08-17 | 1996-03-08 | Fuji Photo Film Co Ltd | ハロゲン化銀写真感光材料 |
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| IT1276833B1 (it) | 1995-10-09 | 1997-11-03 | Sorin Biomedica Cardio Spa | Coloranti fluorescenti della famiglia della solfo benz e indocianina |
| JP3794793B2 (ja) * | 1996-07-24 | 2006-07-12 | アグフア−ゲヴエルト,ナームローゼ・フエンノートシヤツプ | 増感色素を含むフオトサーモグラフイ記録材料及びそのための記録法 |
| US5876915A (en) * | 1996-07-24 | 1999-03-02 | Agfa-Gevaert | Photothermographic recording material comprising sensitizing dyes and a recording process therefor |
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| WO2002038190A2 (en) | 2000-10-27 | 2002-05-16 | Beth Israel Deaconess Medical Center | Non-isotopic detection of osteoblastic activity in vivo using modified bisphosphonates |
| US6615063B1 (en) | 2000-11-27 | 2003-09-02 | The General Hospital Corporation | Fluorescence-mediated molecular tomography |
| EP1209205A1 (en) | 2000-11-28 | 2002-05-29 | Innosense S.r.l. | Improved process and method for the preparation of asymetric monofunctionalised indocyanine labelling reagents and obtained compounds |
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| TNSN03146A1 (fr) | 2001-06-28 | 2005-12-23 | Pfizer Prod Inc | Indoles, benzofurannes et benzothiophenes a substituant triamide, utiles comme inhibiteurs de secretion de la proteine de transfert des triglycerides microsomaux et/ou de l'apolipo-proteine b (apo b). |
| AU2003207438A1 (en) | 2002-01-02 | 2003-07-24 | Visen Medical, Inc. | Amine functionalized superparamagnetic nanoparticles for the synthesis of bioconjugates and uses therefor |
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| JP5643514B2 (ja) | 2007-02-09 | 2014-12-17 | ビセン メディカル, インコーポレイテッド | ポリシクロ染料およびその使用 |
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| US20090037114A1 (en) | 2007-07-30 | 2009-02-05 | Chengbin Peng | 4d+ prestack seismic data structure, and methods and apparatus for processing 4d+ prestack seismic data |
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| CA2715034C (en) | 2008-03-14 | 2016-12-06 | Visen Medical, Inc. | Integrin targeting agents and in-vivo and in-vitro imaging methods using the same |
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-
2008
- 2008-02-08 JP JP2009549253A patent/JP5643514B2/ja active Active
- 2008-02-08 DK DK08729371.8T patent/DK2118206T3/en active
- 2008-02-08 WO PCT/US2008/053399 patent/WO2008100817A2/en not_active Ceased
- 2008-02-08 EP EP08729371.8A patent/EP2118206B9/en active Active
- 2008-02-08 US US12/028,209 patent/US8221721B2/en not_active Expired - Fee Related
- 2008-02-08 ES ES08729371.8T patent/ES2670852T3/es active Active
-
2012
- 2012-07-13 US US13/548,451 patent/US9365721B2/en active Active
-
2014
- 2014-03-31 JP JP2014071365A patent/JP2014167119A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP2118206B9 (en) | 2018-08-29 |
| US8221721B2 (en) | 2012-07-17 |
| WO2008100817A3 (en) | 2009-04-09 |
| JP2014167119A (ja) | 2014-09-11 |
| US20130137873A1 (en) | 2013-05-30 |
| WO2008100817A2 (en) | 2008-08-21 |
| JP2010518236A (ja) | 2010-05-27 |
| US20080286207A1 (en) | 2008-11-20 |
| DK2118206T3 (en) | 2018-06-18 |
| EP2118206A2 (en) | 2009-11-18 |
| ES2670852T3 (es) | 2018-06-01 |
| US9365721B2 (en) | 2016-06-14 |
| EP2118206B1 (en) | 2018-04-11 |
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