JP5632580B2 - 脈管アクセスを改善するための方法および組成物 - Google Patents
脈管アクセスを改善するための方法および組成物 Download PDFInfo
- Publication number
- JP5632580B2 JP5632580B2 JP2008518189A JP2008518189A JP5632580B2 JP 5632580 B2 JP5632580 B2 JP 5632580B2 JP 2008518189 A JP2008518189 A JP 2008518189A JP 2008518189 A JP2008518189 A JP 2008518189A JP 5632580 B2 JP5632580 B2 JP 5632580B2
- Authority
- JP
- Japan
- Prior art keywords
- cells
- implantable material
- graft
- cell
- transport medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title claims 18
- 238000000034 method Methods 0.000 title claims 11
- 230000002792 vascular Effects 0.000 title 1
- 239000006163 transport media Substances 0.000 claims 17
- 210000004027 cell Anatomy 0.000 claims 13
- 230000002401 inhibitory effect Effects 0.000 claims 6
- 239000000463 material Substances 0.000 claims 6
- 238000004113 cell culture Methods 0.000 claims 5
- 230000003833 cell viability Effects 0.000 claims 5
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 4
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 4
- 229920002971 Heparan sulfate Polymers 0.000 claims 2
- 102000004887 Transforming Growth Factor beta Human genes 0.000 claims 2
- 108090001012 Transforming Growth Factor beta Proteins 0.000 claims 2
- 230000007774 longterm Effects 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 claims 2
- 210000003556 vascular endothelial cell Anatomy 0.000 claims 2
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3808—Endothelial cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Botany (AREA)
- Transplantation (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69270805P | 2005-06-21 | 2005-06-21 | |
| US60/692,708 | 2005-06-21 | ||
| USPCT/US2005/043967 | 2005-12-06 | ||
| PCT/US2005/043967 WO2006062909A2 (en) | 2004-12-08 | 2005-12-06 | Methods and compositions for enhancing vascular access |
| PCT/US2006/021755 WO2007001744A2 (en) | 2005-06-21 | 2006-06-05 | Methods and compositions for enhancing vascular access |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012133043A Division JP2012166084A (ja) | 2005-06-21 | 2012-06-12 | 脈管アクセスを改善するための方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008546406A JP2008546406A (ja) | 2008-12-25 |
| JP2008546406A5 JP2008546406A5 (enExample) | 2009-07-16 |
| JP5632580B2 true JP5632580B2 (ja) | 2014-11-26 |
Family
ID=39892157
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008518189A Expired - Fee Related JP5632580B2 (ja) | 2005-06-21 | 2006-06-05 | 脈管アクセスを改善するための方法および組成物 |
| JP2012133043A Withdrawn JP2012166084A (ja) | 2005-06-21 | 2012-06-12 | 脈管アクセスを改善するための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012133043A Withdrawn JP2012166084A (ja) | 2005-06-21 | 2012-06-12 | 脈管アクセスを改善するための方法および組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20090035346A1 (enExample) |
| EP (2) | EP2361591A3 (enExample) |
| JP (2) | JP5632580B2 (enExample) |
| CN (3) | CN101257861B (enExample) |
| AU (1) | AU2006262682B2 (enExample) |
| CA (2) | CA2612751A1 (enExample) |
| ES (1) | ES2541684T3 (enExample) |
| IL (2) | IL188263A (enExample) |
| SG (2) | SG161258A1 (enExample) |
| WO (1) | WO2007001744A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2926510B2 (ja) | 1990-08-09 | 1999-07-28 | 京都電子工業株式会社 | アンモニア濃度測定装置 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006238892B2 (en) | 2005-04-21 | 2011-01-27 | Massachusetts Institute Of Technology | Materials and methods for altering an immune response to exogenous and endogenous immunogens, including syngeneic and non-syngeneic cells, tissues or organs |
| US20090035346A1 (en) | 2005-06-21 | 2009-02-05 | Pervasis Therpeutics, Inc. | Methods and Compositions for Enhancing Vascular Access |
| WO2008057590A2 (en) * | 2006-11-07 | 2008-05-15 | Pervasis Therapeutics, Inc. | Methods and compositions for modulating tissue modeling |
| US20100092532A1 (en) * | 2006-11-07 | 2010-04-15 | Helen Marie Nugent | Materials and Methods for Treating and Managing Angiogenesis-Mediated Diseases |
| JP5806466B2 (ja) * | 2008-01-28 | 2015-11-10 | バイオメット・3アイ・エルエルシー | 親水性を向上させたインプラント表面 |
| WO2012149451A1 (en) * | 2011-04-28 | 2012-11-01 | Abraxis Bioscience, Llc | Intravascular delivery of nanoparticle compositions and uses thereof |
| CN102763642B (zh) * | 2012-08-14 | 2014-04-02 | 郑州赛英科干细胞技术有限公司 | 一种冷冻保护液以及冷冻保存人胎盘羊膜和绒毛膜的方法 |
| CN107670109A (zh) * | 2014-05-27 | 2018-02-09 | 诺瓦赫普有限公司 | 经生物工程改造的同种异体瓣膜 |
| AU2016228986B2 (en) * | 2015-03-10 | 2021-02-04 | Stent Tek Limited | Surgical system, device and methods of use thereof for the percutaneous creation of an arteriovenous fistula (AVF) |
| US12017032B1 (en) | 2017-11-13 | 2024-06-25 | Sbr Innovations, Llc | Arteriovenous graft and method of using thereof |
| US11389622B1 (en) * | 2017-11-13 | 2022-07-19 | Simon B. Rayhanabad | Patch for providing dialysis |
| US11918223B2 (en) | 2018-02-02 | 2024-03-05 | University Of Louisville Research Foundation, Inc. | Sutureless graft anastomotic quick connect system |
| IL311092B2 (en) * | 2018-08-31 | 2025-05-01 | Wisconsin Alumni Res Found | Fabrication of vascular grafts seeded with arterial endothelial cells |
| US12310836B2 (en) | 2020-03-03 | 2025-05-27 | Akeo Hagiwara | Vein cover |
| CN115376392B (zh) * | 2022-08-18 | 2024-04-26 | 昆明理工大学 | 主动脉老化对血管生物力学影响的模拟装置及方法 |
| EP4439070B1 (de) * | 2023-03-27 | 2025-12-03 | Siemens Healthcare Diagnostics Products GmbH | Automatisches analysesystem |
| CN120227529B (zh) * | 2025-05-29 | 2025-08-12 | 鼎科医疗技术(苏州)有限公司 | 一种血管外支架 |
Family Cites Families (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4418691A (en) * | 1981-10-26 | 1983-12-06 | Massachusetts Institute Of Technology | Method of promoting the regeneration of tissue at a wound |
| US4787900A (en) * | 1982-04-19 | 1988-11-29 | Massachusetts Institute Of Technology | Process for forming multilayer bioreplaceable blood vessel prosthesis |
| US4820626A (en) * | 1985-06-06 | 1989-04-11 | Thomas Jefferson University | Method of treating a synthetic or naturally occuring surface with microvascular endothelial cells, and the treated surface itself |
| IL78950A (en) | 1985-06-06 | 1991-12-15 | Univ Jefferson | Coating for prosthetic devices |
| US4732155A (en) * | 1985-08-27 | 1988-03-22 | The Children's Medical Center Corporation | Implantable chemoattractant system |
| US5863531A (en) * | 1986-04-18 | 1999-01-26 | Advanced Tissue Sciences, Inc. | In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework |
| US6309635B1 (en) * | 1986-11-20 | 2001-10-30 | Children's Medical Center Corp. | Seeding parenchymal cells into compression resistant porous scaffold after vascularizing in vivo |
| CA1340581C (en) * | 1986-11-20 | 1999-06-08 | Joseph P. Vacanti | Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices |
| US5567612A (en) * | 1986-11-20 | 1996-10-22 | Massachusetts Institute Of Technology | Genitourinary cell-matrix structure for implantation into a human and a method of making |
| US5804178A (en) * | 1986-11-20 | 1998-09-08 | Massachusetts Institute Of Technology | Implantation of cell-matrix structure adjacent mesentery, omentum or peritoneum tissue |
| US5736372A (en) * | 1986-11-20 | 1998-04-07 | Massachusetts Institute Of Technology | Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure |
| US5073492A (en) * | 1987-01-09 | 1991-12-17 | The Johns Hopkins University | Synergistic composition for endothelial cell growth |
| US5145769A (en) * | 1987-08-21 | 1992-09-08 | Cryolife Inc. | Method for cryopreserving blood vessels |
| US5202120A (en) * | 1987-09-11 | 1993-04-13 | Case Western Reserve University | Methods of reducing glial scar formation and promoting axon and blood vessel growth and/or regeneration through the use of activated immature astrocytes |
| US4945086A (en) | 1988-05-03 | 1990-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Smooth muscle cell growth inhibitor |
| US5575815A (en) * | 1988-08-24 | 1996-11-19 | Endoluminal Therapeutics, Inc. | Local polymeric gel therapy |
| US5843156A (en) * | 1988-08-24 | 1998-12-01 | Endoluminal Therapeutics, Inc. | Local polymeric gel cellular therapy |
| CH676195A5 (enExample) * | 1988-10-07 | 1990-12-28 | Sulzer Ag | |
| JPH03133901A (ja) * | 1989-10-19 | 1991-06-07 | Osaka Gas Co Ltd | 生体細胞の凍結保存方法 |
| US5527532A (en) * | 1989-11-13 | 1996-06-18 | President And Fellows Of Harvard College | Extraluminal regulation of the growth and repair of tubular structures in vivo |
| WO1991007154A1 (en) * | 1989-11-13 | 1991-05-30 | President And Fellows Of Harvard College | EXTRALUMINAL REGULATION OF THE GROWTH AND REPAIR OF TUBULAR STRUCTURES ιIN VIVO |
| US5540928A (en) * | 1991-02-27 | 1996-07-30 | President And Fellows Of Harvard College | Extraluminal regulation of the growth and repair of tubular structures in vivo |
| CA2071137A1 (en) * | 1991-07-10 | 1993-01-11 | Clarence C. Lee | Composition and method for revitalizing scar tissue |
| CA2113089C (en) | 1991-07-15 | 2007-11-06 | Peter J. Sims | Universal donor cells |
| US5336615A (en) | 1992-01-06 | 1994-08-09 | Yale University | Genetically engineered endothelial cells exhibiting enhanced migration and plasminogen activator activity |
| JPH0646840A (ja) * | 1992-08-04 | 1994-02-22 | Nippon Zenyaku Kogyo Kk | 細胞凍結保存液 |
| US5399665A (en) * | 1992-11-05 | 1995-03-21 | Massachusetts Institute Of Technology | Biodegradable polymers for cell transplantation |
| US5981568A (en) * | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6491938B2 (en) * | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| GB9306449D0 (en) * | 1993-03-29 | 1993-05-19 | Nat Heart Research Fund | Tissue equivalents |
| US5709854A (en) * | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
| US5645829A (en) * | 1993-06-18 | 1997-07-08 | Beth Israel Hospital Association | Mesothelial cell gene therapy |
| US6176874B1 (en) * | 1993-10-18 | 2001-01-23 | Masschusetts Institute Of Technology | Vascularized tissue regeneration matrices formed by solid free form fabrication techniques |
| US6608182B1 (en) * | 1994-03-08 | 2003-08-19 | Human Genome Sciences, Inc. | Human vascular endothelial growth factor 2 |
| AU2399495A (en) | 1994-04-29 | 1995-11-29 | W.L. Gore & Associates, Inc. | Improved blood contact surfaces using endothelium on a subendothelial extracellular matrix |
| US5834029A (en) * | 1994-07-20 | 1998-11-10 | Cytotherapeutics, Inc. | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
| ES2155534T3 (es) * | 1994-10-12 | 2001-05-16 | Focal Inc | Administracion dirigida por medio de polimeros biodegradables. |
| US6911216B1 (en) * | 1994-10-12 | 2005-06-28 | Genzyme Corporation | Targeted delivery via biodegradable polymers |
| US5914268A (en) * | 1994-11-21 | 1999-06-22 | National Jewish Center For Immunology & Respiratory Medicine | Embryonic cell populations and methods to isolate such populations |
| US5716404A (en) * | 1994-12-16 | 1998-02-10 | Massachusetts Institute Of Technology | Breast tissue engineering |
| US6281015B1 (en) * | 1994-12-16 | 2001-08-28 | Children's Medical Center Corp. | Localized delivery of factors enhancing survival of transplanted cells |
| US5855610A (en) * | 1995-05-19 | 1999-01-05 | Children's Medical Center Corporation | Engineering of strong, pliable tissues |
| US5766584A (en) * | 1995-06-02 | 1998-06-16 | Massachusetts Institute Of Technology | Inhibition of vascular smooth muscle cell proliferation with implanted matrix containing vascular endothelial cells |
| US6615071B1 (en) * | 1995-09-20 | 2003-09-02 | Board Of Regents, The University Of Texas System | Method and apparatus for detecting vulnerable atherosclerotic plaque |
| US5897987A (en) * | 1996-03-25 | 1999-04-27 | Advanced Reproduction Technologies, Inc. | Use of arabinogalactan in cell cryopreservation media |
| US6886568B2 (en) * | 1998-04-08 | 2005-05-03 | The Johns Hopkins University | Method for fabricating cell-containing implants |
| AU766693B2 (en) * | 1998-11-24 | 2003-10-23 | Emory University | Transgenic circulating endothelial cells |
| US6328762B1 (en) * | 1999-04-27 | 2001-12-11 | Sulzer Biologics, Inc. | Prosthetic grafts |
| US6387116B1 (en) * | 1999-06-30 | 2002-05-14 | Pharmasonics, Inc. | Methods and kits for the inhibition of hyperplasia in vascular fistulas and grafts |
| US6461631B1 (en) * | 1999-11-16 | 2002-10-08 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| AU2001243248A1 (en) * | 2000-02-23 | 2001-09-03 | Smith Kline Beecham Corporation | Method for the prevention or reduction of vascular access dysfunction |
| DE60130544T2 (de) * | 2000-03-13 | 2008-06-26 | Biocure, Inc. | Embolische zusammensetzungen |
| WO2001068158A1 (en) * | 2000-03-15 | 2001-09-20 | Orbus Medical Technologies Inc. | Coating that promotes endothelial cell adherence |
| KR20020086678A (ko) * | 2000-03-24 | 2002-11-18 | 가부시끼가이샤 메니콘 | 조직 등가물의 동결 보존 방법 및 동결 보존된 조직 등가물 |
| US6506398B1 (en) * | 2000-04-28 | 2003-01-14 | Hosheng Tu | Device for treating diabetes and methods thereof |
| US20020042131A1 (en) * | 2000-06-09 | 2002-04-11 | Organ Recovery Systems | Cryopreservation method using cryoprotective composition of propanediol and a vehicle solution |
| AU2001277112A1 (en) | 2000-07-21 | 2002-02-05 | Board Of Regents, The University Of Texas System | Device providing regulated growth factor delivery for the regeneration of peripheral nerves |
| WO2002028387A1 (en) * | 2000-10-03 | 2002-04-11 | Oncopharmaceutical, Inc. | Inhibitors of angiogenesis and tumor growth for local and systemic administration |
| JP2002200161A (ja) * | 2000-10-24 | 2002-07-16 | Menicon Co Ltd | 培養皮膚代替物の製造方法およびそれにより得られる培養皮膚代替物 |
| US6565601B2 (en) * | 2000-11-15 | 2003-05-20 | Micro Therapeutics, Inc. | Methods for vascular reconstruction of diseased arteries |
| EP1389078A4 (en) * | 2000-12-27 | 2004-03-17 | Ortec International Inc | METHOD FOR THE PRODUCTION OF CRYCONSERVED COMPOSED LIVING CONSTRUCTS AND PRODUCTS PRODUCED FROM THEM |
| ES2621652T3 (es) * | 2001-01-16 | 2017-07-04 | Vascular Therapies, Inc. | Dispositivo implantable que contiene material de matriz reabsorbible y rapamicina para evitar o tratar enfermedades vasculoproliferativas |
| US6723131B2 (en) * | 2001-02-28 | 2004-04-20 | The Cleveland Clinic Foundation | Composite bone marrow graft material with method and kit |
| WO2003026489A2 (en) | 2001-09-28 | 2003-04-03 | University Of Florida | Biopolymer and biopolymer-cell compositions for nerve tissue repair |
| US7297540B2 (en) * | 2002-01-15 | 2007-11-20 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Methods of generating tissue using devitalized, acellular scaffold matrices derived from micro-organs |
| US20040047843A1 (en) * | 2002-02-12 | 2004-03-11 | Uab Research Foundation | Method for spinal cord reconnection |
| WO2003083044A2 (en) * | 2002-03-25 | 2003-10-09 | Condros, Inc. | Tissue analogs for in vitro testing and method of use therefor |
| US20050008629A1 (en) * | 2002-05-08 | 2005-01-13 | Interpore Orthopaedics, A Delaware Corporation | Encapsulated AGF cells |
| AU2003250858A1 (en) * | 2002-06-28 | 2004-01-19 | Novartis Ag | Use of organic compounds |
| FR2845691B1 (fr) * | 2002-10-10 | 2004-12-10 | Centre Nat Rech Scient | Nouvelles cellules endotheliales, anticorps diriges contre ces cellules et leur utilisation, notamment pour le criblage de substances inhibant l'angiogenese |
| US20040156878A1 (en) * | 2003-02-11 | 2004-08-12 | Alireza Rezania | Implantable medical device seeded with mammalian cells and methods of treatment |
| WO2004111207A1 (en) * | 2003-06-09 | 2004-12-23 | Centelion | Multicellular in vitro model of angiogenesis and methods for using the same |
| US8192348B2 (en) * | 2003-07-01 | 2012-06-05 | Regents Of The University Of Minnesota | Engineered blood vessels |
| GB0322789D0 (en) * | 2003-09-30 | 2003-10-29 | Lifeforce Group Plc | Blood pack for leukocyte banking |
| US20050106554A1 (en) * | 2003-11-19 | 2005-05-19 | Palecek Sean P. | Cryopreservation of pluripotent stem cells |
| US8067368B2 (en) * | 2004-01-27 | 2011-11-29 | The Ohio State University Research Foundation | Vascular endothelial growth factors and methods of their use |
| ATE506431T1 (de) * | 2004-04-23 | 2011-05-15 | Bioe Llc | Mehrfachlinien-vorläuferzellen |
| FR2869533B1 (fr) | 2004-05-03 | 2006-07-28 | Sedat Sa | Seringue pour interventions medicales et necessaire de reconstitution de substances extemporanees comportant une telle seringue |
| US7842304B2 (en) | 2004-10-29 | 2010-11-30 | Nexeon Medsystems, Inc. | Methods and apparatus for treating an injured nerve pathway |
| WO2006062871A2 (en) | 2004-12-08 | 2006-06-15 | Pervasis Therapeutics, Inc. | Materials and methods for minimally-invasive administration of a cell-containing flowable composition |
| DE602005022481D1 (de) | 2004-12-08 | 2010-09-02 | Pervasis Therapeutics Inc | Zusammensetzungen und deren verwendung für besseren gefässzugang |
| WO2006062909A2 (en) * | 2004-12-08 | 2006-06-15 | Pervasis Therapeutics, Inc. | Methods and compositions for enhancing vascular access |
| AU2006238892B2 (en) | 2005-04-21 | 2011-01-27 | Massachusetts Institute Of Technology | Materials and methods for altering an immune response to exogenous and endogenous immunogens, including syngeneic and non-syngeneic cells, tissues or organs |
| GB0509845D0 (en) | 2005-05-13 | 2005-06-22 | Btg Int Ltd | Preparation of therapeutic foam |
| US20090035346A1 (en) | 2005-06-21 | 2009-02-05 | Pervasis Therpeutics, Inc. | Methods and Compositions for Enhancing Vascular Access |
| JP5015160B2 (ja) | 2005-10-12 | 2012-08-29 | セルラー・バイオエンジニアリング・インコーポレイテッド | 再吸収可能な角膜ボタン(resorbablecorneabutton) |
| US7882863B2 (en) * | 2005-10-19 | 2011-02-08 | Cd Solutions, Llc | Apparatus and method for mixing and transferring medications |
| AU2006348410B2 (en) * | 2005-11-07 | 2011-12-15 | Industrie Borla S.P.A. | Vented safe handling vial adapter |
-
2006
- 2006-06-05 US US11/922,729 patent/US20090035346A1/en not_active Abandoned
- 2006-06-05 AU AU2006262682A patent/AU2006262682B2/en not_active Ceased
- 2006-06-05 EP EP20110001333 patent/EP2361591A3/en not_active Withdrawn
- 2006-06-05 SG SG201002482-6A patent/SG161258A1/en unknown
- 2006-06-05 CN CN2006800279776A patent/CN101257861B/zh not_active Expired - Fee Related
- 2006-06-05 WO PCT/US2006/021755 patent/WO2007001744A2/en not_active Ceased
- 2006-06-05 CA CA 2612751 patent/CA2612751A1/en not_active Abandoned
- 2006-06-05 CA CA 2818182 patent/CA2818182C/en not_active Expired - Fee Related
- 2006-06-05 ES ES06772165.4T patent/ES2541684T3/es active Active
- 2006-06-05 CN CN2010102362140A patent/CN101878757A/zh active Pending
- 2006-06-05 CN CN201210246619.1A patent/CN102743792B/zh not_active Expired - Fee Related
- 2006-06-05 SG SG2013075387A patent/SG195537A1/en unknown
- 2006-06-05 JP JP2008518189A patent/JP5632580B2/ja not_active Expired - Fee Related
- 2006-06-05 EP EP20060772165 patent/EP1901680B1/en not_active Not-in-force
-
2007
- 2007-12-19 IL IL188263A patent/IL188263A/en not_active IP Right Cessation
-
2012
- 2012-06-12 JP JP2012133043A patent/JP2012166084A/ja not_active Withdrawn
- 2012-07-05 IL IL220806A patent/IL220806A/en not_active IP Right Cessation
- 2012-11-02 US US13/667,227 patent/US9023377B2/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2926510B2 (ja) | 1990-08-09 | 1999-07-28 | 京都電子工業株式会社 | アンモニア濃度測定装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| US9023377B2 (en) | 2015-05-05 |
| CA2818182C (en) | 2015-04-14 |
| CN101878757A (zh) | 2010-11-10 |
| JP2008546406A (ja) | 2008-12-25 |
| IL188263A0 (en) | 2009-02-11 |
| ES2541684T3 (es) | 2015-07-23 |
| SG161258A1 (en) | 2010-05-27 |
| WO2007001744A2 (en) | 2007-01-04 |
| CN102743792B (zh) | 2014-09-24 |
| US20130210142A1 (en) | 2013-08-15 |
| US20090035346A1 (en) | 2009-02-05 |
| SG195537A1 (en) | 2013-12-30 |
| IL220806A0 (en) | 2012-08-30 |
| EP1901680B1 (en) | 2015-04-15 |
| CN101257861A (zh) | 2008-09-03 |
| EP2361591A3 (en) | 2011-12-21 |
| CA2612751A1 (en) | 2007-01-04 |
| EP2361591A2 (en) | 2011-08-31 |
| WO2007001744B1 (en) | 2007-12-21 |
| CA2818182A1 (en) | 2007-01-04 |
| IL188263A (en) | 2014-05-28 |
| WO2007001744A3 (en) | 2007-10-04 |
| AU2006262682A1 (en) | 2007-01-04 |
| EP1901680A2 (en) | 2008-03-26 |
| AU2006262682B2 (en) | 2012-07-05 |
| CN102743792A (zh) | 2012-10-24 |
| JP2012166084A (ja) | 2012-09-06 |
| IL220806A (en) | 2014-05-28 |
| CN101257861B (zh) | 2012-12-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2005314263B2 (en) | Methods and compositions for enhancing vascular access | |
| JP2012166084A (ja) | 脈管アクセスを改善するための方法および組成物 | |
| US20100204783A1 (en) | Methods and compositions for enhancing vascular access | |
| ES2348961T3 (es) | Composiciones y su uso para aumentar el acceso vascular. | |
| WO2006062909A2 (en) | Methods and compositions for enhancing vascular access | |
| AU2012238220B2 (en) | Methods and compositions for enhancing vascular access | |
| AU2011211370B2 (en) | Methods and compositions for enhancing vascular access | |
| HK1143517A (en) | Compositions and their use for enhancing vascular access | |
| HK1174859A (en) | Methods and compositions for enhancing vascular access | |
| HK1178466A (en) | Methods and compositions for enhancing vascular access | |
| HK1112429B (en) | Compositions and their use for enhancing vascular access |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20090528 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20090528 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20100524 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20111212 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20120309 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20120312 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20120316 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20120319 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20120612 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20120723 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20121122 |
|
| A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A711 Effective date: 20130118 |
|
| A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20130212 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130416 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20130716 |
|
| A912 | Re-examination (zenchi) completed and case transferred to appeal board |
Free format text: JAPANESE INTERMEDIATE CODE: A912 Effective date: 20130816 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140825 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20141010 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 5632580 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |