JP5626619B2 - 効率的な核初期化方法 - Google Patents
効率的な核初期化方法 Download PDFInfo
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- JP5626619B2 JP5626619B2 JP2008335129A JP2008335129A JP5626619B2 JP 5626619 B2 JP5626619 B2 JP 5626619B2 JP 2008335129 A JP2008335129 A JP 2008335129A JP 2008335129 A JP2008335129 A JP 2008335129A JP 5626619 B2 JP5626619 B2 JP 5626619B2
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
- C12N2310/141—MicroRNAs, miRNAs
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/602—Sox-2
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/604—Klf-4
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/65—MicroRNA
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- C12N2510/00—Genetically modified cells
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- Bioinformatics & Cheminformatics (AREA)
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- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
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- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
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- Emergency Medicine (AREA)
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- Hematology (AREA)
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- Obesity (AREA)
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Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008335129A JP5626619B2 (ja) | 2008-12-08 | 2008-12-26 | 効率的な核初期化方法 |
| US12/379,564 US9683232B2 (en) | 2007-12-10 | 2009-02-25 | Efficient method for nuclear reprogramming |
| EP09252749.8A EP2202309B1 (en) | 2008-12-08 | 2009-12-08 | Efficient method for nuclear reprogramming |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008312745 | 2008-12-08 | ||
| JP2008312745 | 2008-12-08 | ||
| JP2008335129A JP5626619B2 (ja) | 2008-12-08 | 2008-12-26 | 効率的な核初期化方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010158171A JP2010158171A (ja) | 2010-07-22 |
| JP2010158171A5 JP2010158171A5 (enExample) | 2012-02-16 |
| JP5626619B2 true JP5626619B2 (ja) | 2014-11-19 |
Family
ID=42046366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008335129A Active JP5626619B2 (ja) | 2007-12-10 | 2008-12-26 | 効率的な核初期化方法 |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP2202309B1 (enExample) |
| JP (1) | JP5626619B2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2530168Y2 (ja) | 1991-04-12 | 1997-03-26 | 株式会社エヌテック | 製びん機におけるトランスファー装置 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2659945C (en) * | 2005-08-03 | 2014-12-16 | Advanced Cell Technology, Inc. | Improved methods of reprogramming animal somatic cells |
| KR101532442B1 (ko) | 2007-12-10 | 2015-06-29 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 효율적인 핵 초기화 방법 |
| JP5751548B2 (ja) * | 2009-08-07 | 2015-07-22 | 国立大学法人京都大学 | イヌiPS細胞及びその製造方法 |
| WO2011037270A1 (en) * | 2009-09-24 | 2011-03-31 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| EP2537930A4 (en) * | 2010-02-18 | 2013-10-02 | Univ Osaka | METHOD FOR THE PRODUCTION OF INDUCED PLURIPOTENTAL STEM CELLS |
| WO2012073253A1 (en) * | 2010-09-30 | 2012-06-07 | Lakshmanane Boominathan | Therapeutic uses of mirnas/compounds that activate tumor suppressor genes/mirnas |
| JP5888852B2 (ja) * | 2010-12-08 | 2016-03-22 | 学校法人近畿大学 | 免疫不全動物を用いた細胞の製法 |
| WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
| ITRM20110685A1 (it) | 2011-12-23 | 2013-06-24 | Internat Ct For Genetic En Gineering And | Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci |
| CA2876868A1 (en) * | 2012-06-13 | 2013-12-19 | Stemgent, Inc. | Methods of preparing pluripotent stem cells |
| WO2014037574A1 (en) * | 2012-09-10 | 2014-03-13 | Sanofi | Methods for reprogramming a somatic cell |
| JP6893633B2 (ja) * | 2014-07-16 | 2021-06-23 | 国立大学法人京都大学 | 分化細胞の抽出方法 |
| EP4470544A3 (en) * | 2015-11-23 | 2025-06-18 | The Regents of the University of Colorado, a body corporate | Methods and compositions for reprogramming cells |
| CN106939299B (zh) * | 2017-02-04 | 2022-11-15 | 滨州医学院 | microRNA重编程体细胞为神经干细胞的制备方法及应用 |
| JP2023538206A (ja) * | 2020-06-25 | 2023-09-07 | ネクストアンドバイオ インコーポレイテッド | ハイドロゲルを用いない人工多能性幹細胞の製造方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004024940A2 (en) * | 2002-09-16 | 2004-03-25 | University Of Southern California | Rna-mediated gene modulation |
| US9567591B2 (en) * | 2003-05-15 | 2017-02-14 | Mello Biotechnology, Inc. | Generation of human embryonic stem-like cells using intronic RNA |
| WO2005056797A1 (en) * | 2003-12-15 | 2005-06-23 | Kye-Seong Kim | Novel mirna molecules isolated from human embryonic stem cell |
| KR101420740B1 (ko) * | 2005-12-13 | 2014-07-17 | 교또 다이가꾸 | 핵초기화 인자 |
| CN105861443A (zh) * | 2007-04-07 | 2016-08-17 | 怀特黑德生物医学研究所 | 体细胞重编程 |
-
2008
- 2008-12-26 JP JP2008335129A patent/JP5626619B2/ja active Active
-
2009
- 2009-12-08 EP EP09252749.8A patent/EP2202309B1/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2530168Y2 (ja) | 1991-04-12 | 1997-03-26 | 株式会社エヌテック | 製びん機におけるトランスファー装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2202309A1 (en) | 2010-06-30 |
| EP2202309B1 (en) | 2014-04-16 |
| JP2010158171A (ja) | 2010-07-22 |
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