JP5604631B2 - 鉄関連眼病障害の治療および予防へのデフェリプロンの使用 - Google Patents

鉄関連眼病障害の治療および予防へのデフェリプロンの使用 Download PDF

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JP5604631B2
JP5604631B2 JP2011546542A JP2011546542A JP5604631B2 JP 5604631 B2 JP5604631 B2 JP 5604631B2 JP 2011546542 A JP2011546542 A JP 2011546542A JP 2011546542 A JP2011546542 A JP 2011546542A JP 5604631 B2 JP5604631 B2 JP 5604631B2
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Prior art keywords
iron
deferiprone
unit
eye
retinal
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Japanese (ja)
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JP2012515725A (ja
JP2012515725A5 (enExample
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スピーノ,マイケル
ローレンス ドゥナイエフ,ジョシュア
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Apotex Technologies Inc
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Apotex Technologies Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2011546542A 2009-01-26 2009-11-12 鉄関連眼病障害の治療および予防へのデフェリプロンの使用 Expired - Fee Related JP5604631B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14724509P 2009-01-26 2009-01-26
US61/147,245 2009-01-26
PCT/CA2009/001639 WO2010083582A1 (en) 2009-01-26 2009-11-12 Use of deferiprone for treatment and prevention of iron-related eye disorders

Publications (3)

Publication Number Publication Date
JP2012515725A JP2012515725A (ja) 2012-07-12
JP2012515725A5 JP2012515725A5 (enExample) 2012-12-06
JP5604631B2 true JP5604631B2 (ja) 2014-10-08

Family

ID=42355449

Family Applications (1)

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JP2011546542A Expired - Fee Related JP5604631B2 (ja) 2009-01-26 2009-11-12 鉄関連眼病障害の治療および予防へのデフェリプロンの使用

Country Status (24)

Country Link
US (1) US20130023569A1 (enExample)
EP (1) EP2389179A4 (enExample)
JP (1) JP5604631B2 (enExample)
KR (1) KR20120078667A (enExample)
CN (1) CN102348456A (enExample)
AP (1) AP2011005843A0 (enExample)
AU (1) AU2009338093B2 (enExample)
BR (1) BRPI0920492A2 (enExample)
CA (1) CA2750599A1 (enExample)
CL (1) CL2011001812A1 (enExample)
CR (1) CR20110456A (enExample)
EA (1) EA201170970A1 (enExample)
IL (1) IL214291A (enExample)
MA (1) MA33090B1 (enExample)
MX (1) MX2011007947A (enExample)
MY (1) MY161269A (enExample)
NI (1) NI201100148A (enExample)
NZ (1) NZ594728A (enExample)
PE (1) PE20120515A1 (enExample)
SG (1) SG173145A1 (enExample)
TN (1) TN2011000366A1 (enExample)
UA (1) UA103366C2 (enExample)
WO (1) WO2010083582A1 (enExample)
ZA (1) ZA201105514B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016205030B2 (en) * 2015-01-09 2021-04-01 The Board Of Trustees Of The University Of Illinois Restoring physiology in iron-deficient organisms using small molecules
CN111918646B (zh) 2017-10-25 2022-02-22 奇斯药制品公司 延迟释放去铁酮片剂及其使用方法
US12016851B2 (en) 2022-04-11 2024-06-25 Chiesi Farmaceutici S.P.A. Modified release pharmaceutical formulations comprising deferiprone
US12016850B2 (en) 2022-04-11 2024-06-25 Chiesi Farmaceutici S.P.A. Modified release pharmaceutical formulations comprising deferiprone

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046219A (en) * 1995-01-20 2000-04-04 Cornell Research Foundation, Inc. Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation
US5674888A (en) * 1995-06-07 1997-10-07 University Of California Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
AUPQ262499A0 (en) * 1999-09-02 1999-09-23 University Of Queensland, The Novel iron chelators
WO2004041151A2 (en) * 2002-11-07 2004-05-21 Technion Research And Development Foundation Ltd. Neuroprotective iron chelators and pharmaceutical compositions comprising them
EP1601367A2 (en) * 2003-02-06 2005-12-07 Bioresponse L.L.C. The combined use of cruciferous indoles and chelators for the treatment of papillomavirus-related conditions
DK1991225T3 (da) * 2006-02-22 2013-12-16 Apotex Technologies Inc Anvendelse af deferipron og fremgangsmåder til at behandle og/eller forebygge Friedreichs ataksi, der resulterer af intracellulær fejlhåndtering af jern
JP5290147B2 (ja) 2006-04-14 2013-09-18 プラナ バイオテクノロジー リミティッド 加齢黄斑変性症(amd)の処置方法
ITMI20061770A1 (it) * 2006-09-18 2008-03-19 Carlo Ghisalberti Metodo cosmetico di riduzione delle occhiaie
US8501789B2 (en) * 2007-01-19 2013-08-06 The Trustees Of The University Of Pennsylvania Use of salicylaldehyde isonicotinoyl hydrazone (SIH) for protection against retinal disease

Also Published As

Publication number Publication date
EA201170970A1 (ru) 2012-03-30
MA33090B1 (fr) 2012-03-01
NI201100148A (es) 2012-03-06
BRPI0920492A2 (pt) 2019-07-09
UA103366C2 (ru) 2013-10-10
AU2009338093A1 (en) 2011-09-08
EP2389179A1 (en) 2011-11-30
AU2009338093B2 (en) 2014-08-28
JP2012515725A (ja) 2012-07-12
MY161269A (en) 2017-04-14
TN2011000366A1 (en) 2013-03-27
EP2389179A4 (en) 2012-08-29
SG173145A1 (en) 2011-08-29
MX2011007947A (es) 2011-12-14
NZ594728A (en) 2013-03-28
AP2011005843A0 (en) 2011-08-31
CR20110456A (es) 2012-05-31
PE20120515A1 (es) 2012-05-20
WO2010083582A1 (en) 2010-07-29
IL214291A (en) 2015-03-31
CA2750599A1 (en) 2010-07-29
US20130023569A1 (en) 2013-01-24
IL214291A0 (en) 2011-09-27
CL2011001812A1 (es) 2012-02-03
CN102348456A (zh) 2012-02-08
KR20120078667A (ko) 2012-07-10
ZA201105514B (en) 2012-10-31

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