JP5596975B2 - 腫瘍と関連している遺伝的変異 - Google Patents

腫瘍と関連している遺伝的変異 Download PDF

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JP5596975B2
JP5596975B2 JP2009534839A JP2009534839A JP5596975B2 JP 5596975 B2 JP5596975 B2 JP 5596975B2 JP 2009534839 A JP2009534839 A JP 2009534839A JP 2009534839 A JP2009534839 A JP 2009534839A JP 5596975 B2 JP5596975 B2 JP 5596975B2
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nucleotide
mutation
tumor
pro
amino acid
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JP2010508025A (ja
JP2010508025A5 (enExample
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ツェンギャン カン，
デニス エム． ケンスキ，
ブロック ピータース，
ソマセカール セシャギリ，
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ジェネンテック， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2009534839A 2006-10-26 2007-10-24 腫瘍と関連している遺伝的変異 Active JP5596975B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86310606P 2006-10-26 2006-10-26
US60/863,106 2006-10-26
US91781407P 2007-05-14 2007-05-14
US60/917,814 2007-05-14
PCT/US2007/082397 WO2008070325A2 (en) 2006-10-26 2007-10-24 Genetic variations associated with tumors

Publications (3)

Publication Number Publication Date
JP2010508025A JP2010508025A (ja) 2010-03-18
JP2010508025A5 JP2010508025A5 (enExample) 2010-12-16
JP5596975B2 true JP5596975B2 (ja) 2014-10-01

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Family Applications (1)

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JP2009534839A Active JP5596975B2 (ja) 2006-10-26 2007-10-24 腫瘍と関連している遺伝的変異

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US (2) US8680041B2 (enExample)
EP (1) EP2089540B1 (enExample)
JP (1) JP5596975B2 (enExample)
AU (1) AU2007329740B2 (enExample)
CA (1) CA2666057C (enExample)
IL (1) IL198354A (enExample)
MX (1) MX2009004382A (enExample)
NZ (1) NZ576852A (enExample)
WO (1) WO2008070325A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ576852A (en) * 2006-10-26 2012-02-24 Genentech Inc Genetic variations (in the phosphatidylinositol 3-kinase regulatory subunit 1 pik3r1 protein) associated with tumors and method of testing for
GB201001602D0 (en) 2010-02-01 2010-03-17 Cytovation As Oligopeptidic compounds and uses therof
EP2554551A1 (en) * 2011-08-03 2013-02-06 Fundacio Institut mar d'Investigacions Médiques (IMIM) Mutations in the epidermal growth factor receptor gene
JPWO2014017491A1 (ja) * 2012-07-26 2016-07-11 国立研究開発法人国立がん研究センター Ｃｅｐ５５遺伝子とｒｅｔ遺伝子との融合遺伝子
KR101501826B1 (ko) * 2013-04-05 2015-03-13 연세대학교 산학협력단 위암에 대한 예후 예측 모형의 제조방법
WO2015161277A1 (en) * 2014-04-18 2015-10-22 Blueprint Medicines Corporation Met fusions
CN108948175B (zh) * 2018-07-23 2020-11-20 首都医科大学附属北京胸科医院 与人类蛋白smad2相互作用的结核蛋白及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355623B2 (en) * 1998-09-24 2002-03-12 Hopital-Sainte-Justine Method of treating IBD/Crohn's disease and related conditions wherein drug metabolite levels in host blood cells determine subsequent dosage
CA2427858A1 (en) * 2000-11-03 2002-05-10 University Of Vermont And State Agricultural College Compositions for inhibiting grb7
NZ576852A (en) * 2006-10-26 2012-02-24 Genentech Inc Genetic variations (in the phosphatidylinositol 3-kinase regulatory subunit 1 pik3r1 protein) associated with tumors and method of testing for

Also Published As

Publication number Publication date
AU2007329740A1 (en) 2008-06-12
JP2010508025A (ja) 2010-03-18
IL198354A0 (en) 2010-02-17
AU2007329740B2 (en) 2014-05-01
MX2009004382A (es) 2009-06-11
US8680041B2 (en) 2014-03-25
EP2089540A2 (en) 2009-08-19
WO2008070325A2 (en) 2008-06-12
AU2007329740A2 (en) 2009-06-18
CA2666057C (en) 2016-10-11
CA2666057A1 (en) 2008-06-12
IL198354A (en) 2014-11-30
EP2089540B1 (en) 2017-04-19
NZ576852A (en) 2012-02-24
US9631240B2 (en) 2017-04-25
US20100055095A1 (en) 2010-03-04
US20150010537A1 (en) 2015-01-08
WO2008070325A3 (en) 2009-03-05

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