CA2666057C - Genetic variations associated with tumors - Google Patents

Genetic variations associated with tumors Download PDF

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Publication number
CA2666057C
CA2666057C CA2666057A CA2666057A CA2666057C CA 2666057 C CA2666057 C CA 2666057C CA 2666057 A CA2666057 A CA 2666057A CA 2666057 A CA2666057 A CA 2666057A CA 2666057 C CA2666057 C CA 2666057C
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CA
Canada
Prior art keywords
tumor
amino acid
nucleotide
variation
pro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2666057A
Other languages
English (en)
French (fr)
Other versions
CA2666057A1 (en
Inventor
Zhengyan Kan
Denise M. Kenski
Brock Peters
Somasekar Seshagiri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CA2666057A1 publication Critical patent/CA2666057A1/en
Application granted granted Critical
Publication of CA2666057C publication Critical patent/CA2666057C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2666057A 2006-10-26 2007-10-24 Genetic variations associated with tumors Expired - Fee Related CA2666057C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86310606P 2006-10-26 2006-10-26
US60/863,106 2006-10-26
US91781407P 2007-05-14 2007-05-14
US60/917,814 2007-05-14
PCT/US2007/082397 WO2008070325A2 (en) 2006-10-26 2007-10-24 Genetic variations associated with tumors

Publications (2)

Publication Number Publication Date
CA2666057A1 CA2666057A1 (en) 2008-06-12
CA2666057C true CA2666057C (en) 2016-10-11

Family

ID=39462092

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2666057A Expired - Fee Related CA2666057C (en) 2006-10-26 2007-10-24 Genetic variations associated with tumors

Country Status (9)

Country Link
US (2) US8680041B2 (enExample)
EP (1) EP2089540B1 (enExample)
JP (1) JP5596975B2 (enExample)
AU (1) AU2007329740B2 (enExample)
CA (1) CA2666057C (enExample)
IL (1) IL198354A (enExample)
MX (1) MX2009004382A (enExample)
NZ (1) NZ576852A (enExample)
WO (1) WO2008070325A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ576852A (en) * 2006-10-26 2012-02-24 Genentech Inc Genetic variations (in the phosphatidylinositol 3-kinase regulatory subunit 1 pik3r1 protein) associated with tumors and method of testing for
GB201001602D0 (en) 2010-02-01 2010-03-17 Cytovation As Oligopeptidic compounds and uses therof
EP2554551A1 (en) * 2011-08-03 2013-02-06 Fundacio Institut mar d'Investigacions Médiques (IMIM) Mutations in the epidermal growth factor receptor gene
JPWO2014017491A1 (ja) * 2012-07-26 2016-07-11 国立研究開発法人国立がん研究センター Cep55遺伝子とret遺伝子との融合遺伝子
KR101501826B1 (ko) * 2013-04-05 2015-03-13 연세대학교 산학협력단 위암에 대한 예후 예측 모형의 제조방법
WO2015161277A1 (en) * 2014-04-18 2015-10-22 Blueprint Medicines Corporation Met fusions
CN108948175B (zh) * 2018-07-23 2020-11-20 首都医科大学附属北京胸科医院 与人类蛋白smad2相互作用的结核蛋白及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355623B2 (en) * 1998-09-24 2002-03-12 Hopital-Sainte-Justine Method of treating IBD/Crohn's disease and related conditions wherein drug metabolite levels in host blood cells determine subsequent dosage
CA2427858A1 (en) * 2000-11-03 2002-05-10 University Of Vermont And State Agricultural College Compositions for inhibiting grb7
NZ576852A (en) * 2006-10-26 2012-02-24 Genentech Inc Genetic variations (in the phosphatidylinositol 3-kinase regulatory subunit 1 pik3r1 protein) associated with tumors and method of testing for

Also Published As

Publication number Publication date
AU2007329740A1 (en) 2008-06-12
JP2010508025A (ja) 2010-03-18
IL198354A0 (en) 2010-02-17
JP5596975B2 (ja) 2014-10-01
AU2007329740B2 (en) 2014-05-01
MX2009004382A (es) 2009-06-11
US8680041B2 (en) 2014-03-25
EP2089540A2 (en) 2009-08-19
WO2008070325A2 (en) 2008-06-12
AU2007329740A2 (en) 2009-06-18
CA2666057A1 (en) 2008-06-12
IL198354A (en) 2014-11-30
EP2089540B1 (en) 2017-04-19
NZ576852A (en) 2012-02-24
US9631240B2 (en) 2017-04-25
US20100055095A1 (en) 2010-03-04
US20150010537A1 (en) 2015-01-08
WO2008070325A3 (en) 2009-03-05

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