JP5578776B2 - デンドリマー粒子、ｍｒｉ用造影剤及びデンドリマー粒子の製造方法 - Google Patents

デンドリマー粒子、ｍｒｉ用造影剤及びデンドリマー粒子の製造方法 Download PDF

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Publication number
JP5578776B2
JP5578776B2 JP2008230241A JP2008230241A JP5578776B2 JP 5578776 B2 JP5578776 B2 JP 5578776B2 JP 2008230241 A JP2008230241 A JP 2008230241A JP 2008230241 A JP2008230241 A JP 2008230241A JP 5578776 B2 JP5578776 B2 JP 5578776B2
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Japan
Prior art keywords
group
dendrimer
formula
polymerization
fluorine atom
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JP2008230241A
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English (en)
Japanese (ja)
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JP2009235372A (ja
JP2009235372A5 (enExample
Inventor
紳三郎 伊藤
智 仁田原
裕之 青木
公博 吉村
英寿 都築
哲哉 矢野
佳紀 富田
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Canon Inc
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Canon Inc
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Priority to JP2008230241A priority Critical patent/JP5578776B2/ja
Priority to PCT/JP2009/054107 priority patent/WO2009110523A2/en
Publication of JP2009235372A publication Critical patent/JP2009235372A/ja
Publication of JP2009235372A5 publication Critical patent/JP2009235372A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/124—Macromolecular compounds dendrimers, dendrons, hyperbranched compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/028—Polyamidoamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C08L101/02—Compositions of unspecified macromolecular compounds characterised by the presence of specified groups, e.g. terminal or pendant functional groups
    • C08L101/04—Compositions of unspecified macromolecular compounds characterised by the presence of specified groups, e.g. terminal or pendant functional groups containing halogen atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polymerization Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2008230241A 2008-03-03 2008-09-08 デンドリマー粒子、ｍｒｉ用造影剤及びデンドリマー粒子の製造方法 Active JP5578776B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2008230241A JP5578776B2 (ja) 2008-03-03 2008-09-08 デンドリマー粒子、ｍｒｉ用造影剤及びデンドリマー粒子の製造方法
PCT/JP2009/054107 WO2009110523A2 (en) 2008-03-03 2009-02-26 Dendrimer particle, mri contrast medium, and method of manufacturing a dendrimer particle

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008052408 2008-03-03
JP2008052408 2008-03-03
JP2008230241A JP5578776B2 (ja) 2008-03-03 2008-09-08 デンドリマー粒子、ｍｒｉ用造影剤及びデンドリマー粒子の製造方法

Publications (3)

Publication Number Publication Date
JP2009235372A JP2009235372A (ja) 2009-10-15
JP2009235372A5 JP2009235372A5 (enExample) 2011-10-27
JP5578776B2 true JP5578776B2 (ja) 2014-08-27

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JP2008230241A Active JP5578776B2 (ja) 2008-03-03 2008-09-08 デンドリマー粒子、ｍｒｉ用造影剤及びデンドリマー粒子の製造方法

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JP (1) JP5578776B2 (enExample)
WO (1) WO2009110523A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8153729B2 (en) * 2008-05-29 2012-04-10 The Regents Of The University Of California Highly efficient agents for dispersion of nanoparticles in matrix materials
WO2012070681A1 (ja) * 2010-11-26 2012-05-31 国立大学法人九州大学 常磁性を有する水溶性ハイパーブランチポリマー
WO2012074051A1 (ja) * 2010-12-01 2012-06-07 国立大学法人九州大学 含フッ素ハイパーブランチポリマー及びその製造方法
WO2012142670A1 (en) * 2011-04-20 2012-10-26 The University Of Queensland Nuclear magnetic resonance agent
GB2521655A (en) * 2013-12-27 2015-07-01 Nipsea Technologies Pte Ltd Water dispersible dendritic polymers
CN107189075B (zh) * 2017-06-06 2018-03-02 东北石油大学 一种树枝状大分子化合物及其合成方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3653535B2 (ja) * 2000-11-24 2005-05-25 独立行政法人情報通信研究機構 新規チオエーテル誘導体、その製造方法及び用途
US8252778B2 (en) * 2006-03-24 2012-08-28 University Of Utah Research Foundation Highly fluorinated oils and surfactants and methods of making and using same
US8445016B2 (en) * 2006-04-14 2013-05-21 Interface Biologics, Inc. Grafted polymers and uses thereof
US7842390B2 (en) * 2006-10-03 2010-11-30 The Penn State Research Foundation Chain end functionalized fluoropolymers having good electrical properties and good chemical reactivity
JP2008163056A (ja) * 2006-12-26 2008-07-17 Lion Corp ハイパーブランチポリマーの合成方法、ハイパーブランチポリマー、レジスト組成物、半導体集積回路、および半導体集積回路の製造方法
JP2007231292A (ja) * 2007-05-09 2007-09-13 Kaneka Corp 星形重合体の製造方法
US8710151B2 (en) * 2007-12-25 2014-04-29 Nippon Soda Co., Ltd. Onium salt-containing polymer

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WO2009110523A2 (en) 2009-09-11
JP2009235372A (ja) 2009-10-15
WO2009110523A3 (en) 2009-12-10

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