JP5559056B2 - ガンの診断、予測、および予後試験 - Google Patents
ガンの診断、予測、および予後試験 Download PDFInfo
- Publication number
- JP5559056B2 JP5559056B2 JP2010529444A JP2010529444A JP5559056B2 JP 5559056 B2 JP5559056 B2 JP 5559056B2 JP 2010529444 A JP2010529444 A JP 2010529444A JP 2010529444 A JP2010529444 A JP 2010529444A JP 5559056 B2 JP5559056 B2 JP 5559056B2
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- JP
- Japan
- Prior art keywords
- biomarker
- cancer
- level
- aurora
- cell cycle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0720113.0 | 2007-10-15 | ||
| GBGB0720113.0A GB0720113D0 (en) | 2007-10-15 | 2007-10-15 | Diagnostic, prognostic and predictive testing for cancer |
| PCT/GB2008/003501 WO2009050461A1 (en) | 2007-10-15 | 2008-10-15 | Diagnostic, predictive and prognostic testing for cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014018906A Division JP5837630B2 (ja) | 2007-10-15 | 2014-02-03 | ガンの診断、予測、および予後試験 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011501809A JP2011501809A (ja) | 2011-01-13 |
| JP5559056B2 true JP5559056B2 (ja) | 2014-07-23 |
Family
ID=38813827
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010529444A Expired - Fee Related JP5559056B2 (ja) | 2007-10-15 | 2008-10-15 | ガンの診断、予測、および予後試験 |
| JP2014018906A Expired - Fee Related JP5837630B2 (ja) | 2007-10-15 | 2014-02-03 | ガンの診断、予測、および予後試験 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014018906A Expired - Fee Related JP5837630B2 (ja) | 2007-10-15 | 2014-02-03 | ガンの診断、予測、および予後試験 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US8512716B2 (https=) |
| EP (1) | EP2208070B1 (https=) |
| JP (2) | JP5559056B2 (https=) |
| CN (1) | CN101896819A (https=) |
| AU (1) | AU2008313459B2 (https=) |
| CA (1) | CA2702653A1 (https=) |
| DK (1) | DK2208070T3 (https=) |
| ES (1) | ES2395890T3 (https=) |
| GB (1) | GB0720113D0 (https=) |
| PT (1) | PT2208070E (https=) |
| WO (1) | WO2009050461A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0921873D0 (en) * | 2009-12-15 | 2010-01-27 | Cytosystems Ltd | Assay |
| WO2012012693A2 (en) * | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods for detecting signatures of disease or conditions in bodily fluids |
| AU2013388864B2 (en) * | 2013-05-09 | 2017-06-08 | The Procter & Gamble Company | Method and system for assessing health condition |
| CN103592444A (zh) * | 2013-11-27 | 2014-02-19 | 中国人民解放军沈阳军区总医院 | 一种检测乳腺癌中cyclin G1蛋白表达并进行预后评估的方法 |
| US9857354B2 (en) | 2014-06-01 | 2018-01-02 | Novazoi Theranostics, Inc. | Compositions and methods for prognosis and treatment of neoplasm |
| WO2016131875A1 (en) * | 2015-02-17 | 2016-08-25 | Biontech Diagnostics Gmbh | Methods and kits for the molecular subtyping of bladder cancer |
| CN107771285A (zh) | 2015-06-08 | 2018-03-06 | 阿奎尔诊断有限公司 | 方法 |
| EP4060344A1 (en) | 2015-06-08 | 2022-09-21 | Arquer Diagnostics Limited | Methods and kits |
| CN105986034A (zh) * | 2016-06-15 | 2016-10-05 | 南京卡迪睿伯生物技术有限公司 | 一组胃癌基因的应用 |
| CN108344867B (zh) * | 2018-01-23 | 2020-05-15 | 郑州大学第一附属医院 | 人组蛋白H3 Ser10和Ser28在鉴定人卵母细胞成熟分期中的应用 |
| CN108344868B (zh) * | 2018-01-23 | 2020-05-15 | 郑州大学第一附属医院 | 人组蛋白H3 Ser10和Ser28在鉴定人早期胚胎的发育分期中的应用 |
| CN111187833A (zh) * | 2018-11-14 | 2020-05-22 | 上海生物芯片有限公司 | Plk1和bub1b基因联合作为肺癌生物标志物的用途 |
| GB201820867D0 (en) * | 2018-12-20 | 2019-02-06 | Arquer Diagnostics Ltd | Detection method |
| CN109988708B (zh) * | 2019-02-01 | 2022-12-09 | 碳逻辑生物科技(中山)有限公司 | 一种用于对患有结肠直肠癌的患者进行分型的系统 |
| CN110846413B (zh) * | 2019-11-23 | 2023-05-26 | 中南大学湘雅三医院 | Mafg/mafg-as1/mafg正反馈环作为靶位点检测试剂的应用 |
| CN114019163B (zh) * | 2021-11-02 | 2024-07-23 | 复旦大学附属中山医院 | 基于活化b细胞表达的结肠癌预后诊断用标记物及其用途 |
| WO2023150578A2 (en) * | 2022-02-01 | 2023-08-10 | 4D Path Inc. | Systems and methods for image-based disease characterization |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4329177A1 (de) * | 1993-08-30 | 1995-03-02 | Chemotherapeutisches Forschungsinstitut Georg Speyer Haus | Klonierung eines neuen Mitgliedes der Familie der Serin-Threonin-Kinasen |
| DE19915057A1 (de) | 1999-04-01 | 2000-10-19 | Forschungszentrum Borstel | Monoklonale Antikörper gegen das humane Mcm3 Protein, Verfahren zu ihrer Herstellung und ihre Verwendung |
| EP1422526A1 (en) | 2002-10-28 | 2004-05-26 | MTM Laboratories AG | Method for improved diagnosis of dysplasias |
| US20040231909A1 (en) * | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| GB0323225D0 (en) * | 2003-10-03 | 2003-11-05 | Ncc Technology Ventures Pte Lt | Materials and methods relating to breast cancer classification |
| CA2563074C (en) * | 2004-04-09 | 2014-05-20 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| CA2563168A1 (en) * | 2004-04-14 | 2005-11-17 | President And Fellows Of Harvard College | Nucleic-acid programmable protein arrays |
| EP1805676A1 (en) * | 2004-09-22 | 2007-07-11 | Tripath Imaging, Inc. | Methods and computer program products for analysis and optimization of marker candidates for cancer prognosis |
| ATE464395T1 (de) * | 2005-02-18 | 2010-04-15 | Astrazeneca Ab | Verfahren zur bestimmung der reaktionsfähigkeit gegenüber chk1-inhibitoren |
| EP1968579A1 (en) * | 2005-12-30 | 2008-09-17 | Astex Therapeutics Limited | Pharmaceutical compounds |
| ATE456053T1 (de) * | 2005-12-30 | 2010-02-15 | Ventana Med Syst Inc | Na+, k+-atpase-expression bei zervixdysplasie und krebs |
-
2007
- 2007-10-15 GB GBGB0720113.0A patent/GB0720113D0/en not_active Ceased
-
2008
- 2008-10-15 DK DK08840139.3T patent/DK2208070T3/da active
- 2008-10-15 WO PCT/GB2008/003501 patent/WO2009050461A1/en not_active Ceased
- 2008-10-15 AU AU2008313459A patent/AU2008313459B2/en not_active Ceased
- 2008-10-15 EP EP08840139A patent/EP2208070B1/en not_active Not-in-force
- 2008-10-15 US US12/738,062 patent/US8512716B2/en not_active Expired - Fee Related
- 2008-10-15 CN CN2008801209233A patent/CN101896819A/zh active Pending
- 2008-10-15 JP JP2010529444A patent/JP5559056B2/ja not_active Expired - Fee Related
- 2008-10-15 PT PT88401393T patent/PT2208070E/pt unknown
- 2008-10-15 ES ES08840139T patent/ES2395890T3/es active Active
- 2008-10-15 CA CA2702653A patent/CA2702653A1/en not_active Abandoned
-
2013
- 2013-04-30 US US13/873,487 patent/US20140154680A1/en not_active Abandoned
-
2014
- 2014-02-03 JP JP2014018906A patent/JP5837630B2/ja not_active Expired - Fee Related
-
2016
- 2016-04-29 US US15/141,908 patent/US20180223366A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US8512716B2 (en) | 2013-08-20 |
| CN101896819A (zh) | 2010-11-24 |
| US20140154680A1 (en) | 2014-06-05 |
| PT2208070E (pt) | 2013-01-08 |
| CA2702653A1 (en) | 2009-04-23 |
| EP2208070A1 (en) | 2010-07-21 |
| GB0720113D0 (en) | 2007-11-28 |
| DK2208070T3 (da) | 2012-12-17 |
| US20180223366A1 (en) | 2018-08-09 |
| JP2014095726A (ja) | 2014-05-22 |
| AU2008313459A1 (en) | 2009-04-23 |
| ES2395890T3 (es) | 2013-02-15 |
| JP5837630B2 (ja) | 2015-12-24 |
| US20100285474A1 (en) | 2010-11-11 |
| EP2208070B1 (en) | 2012-10-03 |
| WO2009050461A1 (en) | 2009-04-23 |
| AU2008313459B2 (en) | 2013-01-24 |
| JP2011501809A (ja) | 2011-01-13 |
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