JP5557740B2 - 不連続用量の薬剤を投与するためのモジュラー型薬品送達デバイス - Google Patents
不連続用量の薬剤を投与するためのモジュラー型薬品送達デバイス Download PDFInfo
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1413—Modular systems comprising interconnecting elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
Description
この請求項において開示されるものは、特に、複数の、不連続用量の薬剤を供給するように適応され、かつ、ユーザーによって装着されるように適応される使い捨ての送達ユニット、及び別個の、再使用可能なベースユニットを含む、薬品送達デバイスである。この使い捨ての送達ユニットは、送達される薬剤を保持するためのリザーバー、薬剤の経皮送達のために適応される注入部材、及び、送達される薬剤をリザーバーから注入部材へ汲み出すように適応されるポンプを含む。別個の、再使用可能なベースユニットは、ポンプを駆動するための駆動モジュールを含む。ベースユニットを送達ユニットに一時的にドッキングし、それによってベースユニットが送達ユニットとパワーを通じてポンプを駆動すると、使い捨ての送達ユニット中のポンプが活性化されて、ある用量の薬剤を送達する。本明細書では、「経皮」という用語は、もっとも広い意味で理解しなければならず、皮膚の中に浸透するか、又は横断する薬品送達であるならばいずれのタイプの薬品送達でも、皮下、筋肉内、腹腔内、静脈内、脊髄性、動脈内、及び皮内を含む薬品送達も含むことが意図される。
ポンプを駆動するための駆動モジュールを含む、別個の、再使用可能なベースユニットを一時的に送達ユニットと通じ合う状態に置き、それによって、ポンプを活性化してある用量の薬剤をリザーバーから注入部材に輸送すること、を含む方法が提供される。
Claims (15)
- 複数の不連続用量の薬剤を供給するための薬品送達デバイスであって、前記薬品送達デバイスは、ユーザーによって装着されるように構成される使い捨ての送達ユニットと、別個の再使用可能なベースユニットとを含み、
前記送達ユニットが、送達される薬剤を保持するためのリザーバーを含むチャンバーを定める筐体と、経皮薬剤輸送のために適応される注入部材と、前記送達される薬剤を前記リザーバーから前記注入部材に向けて汲み出すためのポンプと、前記ユーザーの皮膚に対し前記送達ユニットを接着的に搭載するように適応される接着性ベースを含む搭載下面と、外方ドッキング界面とを含み、
前記ベースユニットが、前記ポンプを駆動してある用量の薬剤を送達するための駆動モジュールと、前記送達ユニットの外方ドッキング界面に対して設置されるように構成される相補的外方ドッキング界面とを有し、
前記ベースユニットと前記送達ユニットとの間にどのような機械的接続又は取り付けも必要とせずに、前記ベースユニットを前記使い捨ての送達ユニットと一時的に近接して配置させることによって、前記ベースユニットが前記送達ユニットと一時的に無接触パワーが通じ合う状態に設置されるように構成され、それによって、前記ポンプが活性化され、ある用量の薬剤を前記リザーバーから前記注入部材に向けて汲み出すように構成され、
前記設置は、前記ベースユニットが前記送達ユニットに対し無接触パワーが通じ合う状態となるように前記ベースユニットを前記送達ユニットの上に一時的に位置づける際に前記ベースユニットがガイドされるように行われる
ことを特徴とする薬品送達デバイス。
- 前記ベースユニットが、電源と、前記ポンプ及びユーザーインターフェイスの操作を調節するための電子回路とを含む請求項1記載の薬品送達デバイス。
- 前記ベースユニットが、少なくとも最終送達投与の量、1回以上の投与以後に経過した時間、及び/又は、ある期間に投与された投与の数及び/又は量、のうちの一つ以上を監視するように適応されるメモリーデバイスを含む請求項1又は2記載の薬品送達デバイス。
- 前記メモリーデバイスがアラーム機能を含む請求項3記載の薬品送達デバイス。
- 前記メモリーデバイスが時間予告を含む請求項3又は4記載の薬品送達デバイス。
- 前記注入部材が、注射針又はカニューレである請求項1ないし5いずれか1項に記載の薬品送達デバイス。
- 前記送達ユニットは、この送達ユニットのパラメータが指定の範囲を逸脱した場合、アラームを活性化するように適応されるコンデンサーを含む請求項1ないし6いずれか1項に記載の薬品送達デバイス。
- 前記ポンプが、永久磁石付きのローターを含む請求項1ないし7いずれか1項に記載の薬品送達デバイス。
- 前記送達ユニットが、前記ベースユニットによって生起される変動性磁場からのパワーを受容するように構成される一つ又は複数の変換コイルを含む請求項1ないし8いずれか1項に記載の薬品送達デバイス。
- 前記駆動モジュールが、前記送達ユニットポンプのローター上に配される永久磁石を駆動するための、又は前記送達ユニット中の1個以上のコイルに電流を誘起するための電磁石を含む請求項8記載の薬品送達デバイス。
- 前記駆動モジュールが、前記送達ユニットポンプのローター上に配される永久磁石を駆動するために、又は前記送達ユニット中の1個以上のコイルに電流を誘起するために、前記ローター上に永久磁石と、前記ローターを駆動し回転させるように構成されるモーターとを含む請求項8記載の薬品送達デバイス。
- 前記ローター及び前記駆動モジュールが、パルスモーターとして動作する請求項8記載の薬品送達デバイス。
- 前記ベースユニットは、前記送達ユニットの非搭載上面に対し本質的に相補的形状を持つ陥凹部分を有する密着下面を含み、そのために前記ベースユニットを前記送達ユニットの上に位置づけかつガイドすることが可能とされる請求項1ないし12いずれか1項に記載の薬品送達デバイス。
- 前記リザーバーが、潰すことができるリザーバーか、又はコイル型リザーバーである請求項1ないし13いずれか1項に記載の薬品送達デバイス。
- 前記薬剤がインスリンである請求項1ないし14いずれか1項に記載の薬品送達デバイス。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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EP07405230.9 | 2007-08-07 | ||
EP07405230A EP2022518A1 (en) | 2007-08-07 | 2007-08-07 | Modular drug delivery device for administering discrete doses of a medicament |
PCT/IB2008/053113 WO2009019648A1 (en) | 2007-08-07 | 2008-08-04 | Modular drug delivery device for administering discrete doses of a medicament |
Publications (3)
Publication Number | Publication Date |
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JP2010535569A JP2010535569A (ja) | 2010-11-25 |
JP2010535569A5 JP2010535569A5 (ja) | 2011-03-24 |
JP5557740B2 true JP5557740B2 (ja) | 2014-07-23 |
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JP2010519555A Active JP5557740B2 (ja) | 2007-08-07 | 2008-08-04 | 不連続用量の薬剤を投与するためのモジュラー型薬品送達デバイス |
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US (1) | US8414532B2 (ja) |
EP (2) | EP2022518A1 (ja) |
JP (1) | JP5557740B2 (ja) |
CN (1) | CN101772359B (ja) |
AU (1) | AU2008285173B2 (ja) |
CA (1) | CA2693913C (ja) |
WO (1) | WO2009019648A1 (ja) |
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AU2008285173A1 (en) | 2009-02-12 |
CA2693913C (en) | 2016-03-29 |
CN101772359A (zh) | 2010-07-07 |
CA2693913A1 (en) | 2009-02-12 |
EP2022518A1 (en) | 2009-02-11 |
WO2009019648A1 (en) | 2009-02-12 |
JP2010535569A (ja) | 2010-11-25 |
EP2190499A1 (en) | 2010-06-02 |
US20110196337A1 (en) | 2011-08-11 |
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