JP5539653B2 - 細胞脂肪を減少させるため、心毒性を予測するため、チロシンキナーゼ阻害剤による処置による組成物および方法 - Google Patents
細胞脂肪を減少させるため、心毒性を予測するため、チロシンキナーゼ阻害剤による処置による組成物および方法 Download PDFInfo
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Classifications
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- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5061—Muscle cells
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- C—CHEMISTRY; METALLURGY
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
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- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
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- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
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| US86773606P | 2006-11-29 | 2006-11-29 | |
| US60/867,736 | 2006-11-29 | ||
| PCT/US2007/062871 WO2007101191A2 (en) | 2006-02-27 | 2007-02-27 | Compositions and methods for reducing cellular fat and for predicting cardiac toxicity and upon treatment with tyrosine kinase inhibitors |
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| JP2012282502A Pending JP2013063090A (ja) | 2006-02-27 | 2012-12-26 | 細胞脂肪を減少させるため、心毒性を予測するため、チロシンキナーゼ阻害剤による処置による組成物および方法 |
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| US (2) | US8709738B2 (https=) |
| EP (1) | EP1996939B1 (https=) |
| JP (2) | JP5539653B2 (https=) |
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| ES (1) | ES2475162T3 (https=) |
| IL (1) | IL193715A (https=) |
| NZ (2) | NZ594178A (https=) |
| WO (1) | WO2007101191A2 (https=) |
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| WO2010036910A1 (en) * | 2008-09-26 | 2010-04-01 | Yoshikazu Ohta | Heart protection by administering an amp-activated protein kinase activator |
| WO2015027171A1 (en) * | 2013-08-23 | 2015-02-26 | Quintiles Transnational Corporation | Methods for predicting toxicity in response to treatment with a drug by assessing activation of the sterol regulatory binding protein (srebp) pathway |
| EP3739041A1 (en) | 2014-03-27 | 2020-11-18 | The Salk Institute for Biological Studies | Compositions and methods for treating type 1 and type 2 diabetes and related disorders |
| AU2016225076B2 (en) | 2015-02-27 | 2018-09-13 | Salk Institute For Biological Studies | Reprogramming progenitor compositions and methods of use therefore |
| AU2017269364B2 (en) | 2016-05-25 | 2023-08-31 | Salk Institute For Biological Studies | Compositions and methods for organoid generation and disease modeling |
| JP7032723B2 (ja) * | 2017-07-21 | 2022-03-09 | 公立大学法人福島県立医科大学 | 薬剤の心毒性評価方法及びそのための試薬又はキット |
| WO2019084395A1 (en) * | 2017-10-27 | 2019-05-02 | University Of Virginia Patent Foundation | COMPOUNDS AND METHODS FOR REGULATING, LIMITING OR INHIBITING AVIL EXPRESSION |
| TWI711458B (zh) * | 2019-07-08 | 2020-12-01 | 大江生醫股份有限公司 | 植物發酵物及其製備方法與用於胃臟保健的用途 |
| KR102493664B1 (ko) | 2020-01-29 | 2023-02-01 | 한국화학연구원 | 심장 독성 예측 모델링 시스템 및 모델링 방법 |
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| DE19932555A1 (de) * | 1999-07-13 | 2001-01-18 | Solvay Pharm Gmbh | Arzneimittel mit protektiver Wirkung gegen oxidativ-toxische und insbesondere gegen kardiotoxische Substanzen |
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| CA2459508A1 (en) * | 2001-09-24 | 2003-04-03 | Lipomics Technologies, Inc. | Methods of using quantitative lipid metabolome data |
| JP4611025B2 (ja) * | 2002-11-04 | 2011-01-12 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 体内のブドウ糖または脂肪酸の代謝に関する高処理量測定のための重水素化ブドウ糖または脂肪の耐性試験 |
| EP1980629A3 (en) | 2003-08-28 | 2008-12-17 | Ipsogen | Identification of an erbb2 gene expression signature in breast cancers |
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| KR20090008194A (ko) | 2009-01-21 |
| CN103217520A (zh) | 2013-07-24 |
| EP1996939A2 (en) | 2008-12-03 |
| NZ594178A (en) | 2013-02-22 |
| AU2007220094B2 (en) | 2013-12-05 |
| EP1996939A4 (en) | 2009-07-15 |
| IL193715A (en) | 2014-06-30 |
| KR101390625B1 (ko) | 2014-04-29 |
| WO2007101191A2 (en) | 2007-09-07 |
| NZ571465A (en) | 2011-09-30 |
| CN101438155A (zh) | 2009-05-20 |
| EP1996939B1 (en) | 2014-03-26 |
| WO2007101191A3 (en) | 2007-12-13 |
| JP2009533017A (ja) | 2009-09-17 |
| CA2643846A1 (en) | 2007-09-07 |
| ES2475162T3 (es) | 2014-07-10 |
| US20090186910A1 (en) | 2009-07-23 |
| JP2013063090A (ja) | 2013-04-11 |
| CN101438155B (zh) | 2013-04-24 |
| US20130288285A1 (en) | 2013-10-31 |
| US8709738B2 (en) | 2014-04-29 |
| AU2007220094A1 (en) | 2007-09-07 |
| IL193715A0 (en) | 2009-05-04 |
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