JP5528331B2 - イオン検出方法およびイオン検出器システム - Google Patents

イオン検出方法およびイオン検出器システム Download PDF

Info

Publication number
JP5528331B2
JP5528331B2 JP2010508903A JP2010508903A JP5528331B2 JP 5528331 B2 JP5528331 B2 JP 5528331B2 JP 2010508903 A JP2010508903 A JP 2010508903A JP 2010508903 A JP2010508903 A JP 2010508903A JP 5528331 B2 JP5528331 B2 JP 5528331B2
Authority
JP
Japan
Prior art keywords
mass
signal
intensity
ion
charge ratio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2010508903A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010528280A (ja
JP2010528280A5 (enExample
Inventor
グリーン・マーティン
プリングル・スティーブン・デレク
ワイルドグース・ジェイソン・リー
Original Assignee
マイクロマス ユーケー リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マイクロマス ユーケー リミテッド filed Critical マイクロマス ユーケー リミテッド
Publication of JP2010528280A publication Critical patent/JP2010528280A/ja
Publication of JP2010528280A5 publication Critical patent/JP2010528280A5/ja
Application granted granted Critical
Publication of JP5528331B2 publication Critical patent/JP5528331B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/022—Circuit arrangements, e.g. for generating deviation currents or voltages ; Components associated with high voltage supply
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
JP2010508903A 2007-05-22 2008-05-22 イオン検出方法およびイオン検出器システム Active JP5528331B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB0709799.1A GB0709799D0 (en) 2007-05-22 2007-05-22 Mass spectrometer
GB0709799.1 2007-05-22
US94621107P 2007-06-26 2007-06-26
US60/946,211 2007-06-26
PCT/GB2008/001756 WO2008142418A2 (en) 2007-05-22 2008-05-22 Mass spectrometer

Publications (3)

Publication Number Publication Date
JP2010528280A JP2010528280A (ja) 2010-08-19
JP2010528280A5 JP2010528280A5 (enExample) 2011-09-01
JP5528331B2 true JP5528331B2 (ja) 2014-06-25

Family

ID=38234872

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010508903A Active JP5528331B2 (ja) 2007-05-22 2008-05-22 イオン検出方法およびイオン検出器システム

Country Status (6)

Country Link
US (3) US8354634B2 (enExample)
EP (3) EP2184763B1 (enExample)
JP (1) JP5528331B2 (enExample)
CA (1) CA2687420C (enExample)
GB (2) GB0709799D0 (enExample)
WO (1) WO2008142418A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3286852B2 (ja) 1992-08-20 2002-05-27 株式会社キーエンス 荷重変化点検出装置の基準変動量設定装置

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0709799D0 (en) * 2007-05-22 2007-06-27 Micromass Ltd Mass spectrometer
GB0909289D0 (en) * 2009-05-29 2009-07-15 Micromass Ltd Method of processing mass spectral data
IT1395787B1 (it) * 2009-09-16 2012-10-19 Dani Instr Spa Spettrometro di massa ad ampio intervallo di dinamica.
DE102010056152A1 (de) * 2009-12-31 2011-07-07 Spectro Analytical Instruments GmbH, 47533 Simultanes anorganisches Massenspektrometer und Verfahren zur anorganischen Massenspektrometrie
US9330892B2 (en) 2009-12-31 2016-05-03 Spectro Analytical Instruments Gmbh Simultaneous inorganic mass spectrometer and method of inorganic mass spectrometry
JP5781545B2 (ja) * 2010-02-02 2015-09-24 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 飛行時間型質量分析検出システムを操作する方法およびシステム
GB201002447D0 (en) * 2010-02-12 2010-03-31 Micromass Ltd Mass spectrometer
DE102010011974B4 (de) 2010-03-19 2016-09-15 Bruker Daltonik Gmbh Sättigungskorrektur für Ionensignale in Flugzeitmassenspektrometern
CA2819024C (en) 2010-12-17 2016-07-12 Thermo Fisher Scientific (Bremen) Gmbh Data acquisition system and method for mass spectrometry
GB201106689D0 (en) * 2011-04-20 2011-06-01 Micromass Ltd Function switching with fast asynchronous acquisition
JP5889403B2 (ja) * 2011-06-03 2016-03-22 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド スキャン内ダイナミックレンジを改善するための可変窓バンドパスフィルタリングを使用する調査スキャンからのイオンの除去
GB201208841D0 (en) * 2012-05-18 2012-07-04 Micromass Ltd Calibrating dual adc acquisition system
US10354849B2 (en) * 2013-07-09 2019-07-16 Micromass Uk Limited Method of recording ADC saturation
GB201312266D0 (en) * 2013-07-09 2013-08-21 Micromass Ltd Method of recording ADC saturation
US9576781B2 (en) * 2013-07-09 2017-02-21 Micromass Uk Limited Intelligent dynamic range enhancement
DE112015002258B4 (de) * 2014-05-13 2023-09-21 Micromass Uk Limited Mehrdimensionale Ionentrennung
US9928999B2 (en) 2014-06-11 2018-03-27 Micromass Uk Limited Flagging ADC coalescence
GB201410382D0 (en) * 2014-06-11 2014-07-23 Micromass Ltd Flagging ADC coalescence
GB201514643D0 (en) * 2015-08-18 2015-09-30 Micromass Ltd Mass Spectrometer data acquisition
GB201515357D0 (en) 2015-08-28 2015-10-14 Micromass Ltd Mass spectrometer with digitial step attenuator
GB2544959B (en) * 2015-09-17 2019-06-05 Thermo Fisher Scient Bremen Gmbh Mass spectrometer
US10026598B2 (en) * 2016-01-04 2018-07-17 Rohde & Schwarz Gmbh & Co. Kg Signal amplitude measurement and calibration with an ion trap
CN105609401B (zh) * 2016-02-17 2017-10-24 广州禾信分析仪器有限公司 一种提高飞行时间质谱仪器动态检测范围的方法及系统
US20170263426A1 (en) * 2016-03-10 2017-09-14 Leco Corporation Dynamic Baseline Adjuster
GB201613988D0 (en) 2016-08-16 2016-09-28 Micromass Uk Ltd And Leco Corp Mass analyser having extended flight path
GB201618023D0 (en) 2016-10-25 2016-12-07 Micromass Uk Limited Ion detection system
GB2567794B (en) 2017-05-05 2023-03-08 Micromass Ltd Multi-reflecting time-of-flight mass spectrometers
GB2563571B (en) 2017-05-26 2023-05-24 Micromass Ltd Time of flight mass analyser with spatial focussing
US11211238B2 (en) 2017-08-06 2021-12-28 Micromass Uk Limited Multi-pass mass spectrometer
WO2019030472A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov IONIC MIRROR FOR MULTI-REFLECTION MASS SPECTROMETERS
EP3662503A1 (en) 2017-08-06 2020-06-10 Micromass UK Limited Ion injection into multi-pass mass spectrometers
WO2019030477A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov ACCELERATOR FOR MASS SPECTROMETERS WITH MULTIPASSES
WO2019030474A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov IONIC MIRROR WITH PRINTED CIRCUIT WITH COMPENSATION
WO2019030473A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov FIELDS FOR SMART REFLECTIVE TOF SM
WO2019030471A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov ION GUIDE INSIDE PULSED CONVERTERS
GB201806507D0 (en) 2018-04-20 2018-06-06 Verenchikov Anatoly Gridless ion mirrors with smooth fields
GB201807605D0 (en) 2018-05-10 2018-06-27 Micromass Ltd Multi-reflecting time of flight mass analyser
GB201807626D0 (en) 2018-05-10 2018-06-27 Micromass Ltd Multi-reflecting time of flight mass analyser
GB201808530D0 (en) 2018-05-24 2018-07-11 Verenchikov Anatoly TOF MS detection system with improved dynamic range
GB201810573D0 (en) 2018-06-28 2018-08-15 Verenchikov Anatoly Multi-pass mass spectrometer with improved duty cycle
GB201901411D0 (en) 2019-02-01 2019-03-20 Micromass Ltd Electrode assembly for mass spectrometer
GB201903779D0 (en) 2019-03-20 2019-05-01 Micromass Ltd Multiplexed time of flight mass spectrometer
GB202110412D0 (en) * 2021-07-20 2021-09-01 Micromass Ltd Mass spectrometer for generating and summing mass spectral data
CN120604117A (zh) * 2023-02-03 2025-09-05 株式会社岛津制作所 质量分析方法及质量分析装置
CN116593569B (zh) * 2023-05-18 2025-10-28 北京清谱科技有限公司 一种拓展检测器动态范围的方法、装置及电子设备
WO2025144683A1 (en) * 2023-12-28 2025-07-03 Intabio, Llc External ion source spatial positioning analysis
US20250322913A1 (en) * 2024-04-11 2025-10-16 MOBILion Systems, Inc. Systems and Methods for Enhanced Acquisition of Mass Spectrometry Data

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5760654A (en) * 1980-09-26 1982-04-12 Jeol Ltd Spectral detecting method
US4490806A (en) * 1982-06-04 1984-12-25 Research Corporation High repetition rate transient recorder with automatic integration
JPS61207962A (ja) * 1985-03-12 1986-09-16 Jeol Ltd 質量分析計の質量較正方法
JPH09184823A (ja) * 1995-12-28 1997-07-15 Shimadzu Corp 分析装置の検出信号処理装置
JP2001524808A (ja) * 1996-12-10 2001-12-04 ジーントレイス・システムズ・インコーポレイテッド 放出可能な不揮発性の質量標識分子
US6259101B1 (en) * 1997-09-23 2001-07-10 University Of Delaware Method and instruments for the on-line detection, sizing or analysis of aerosol particles
US6195031B1 (en) * 1998-12-28 2001-02-27 Siemens Aktiengesellschaft Analog-to-digital converter with level converter and level recognition unit and correction memory
GB9920711D0 (en) * 1999-09-03 1999-11-03 Hd Technologies Limited High dynamic range mass spectrometer
US7038197B2 (en) * 2001-04-03 2006-05-02 Micromass Limited Mass spectrometer and method of mass spectrometry
US7265346B2 (en) * 2001-05-25 2007-09-04 Analytica Of Brandford, Inc. Multiple detection systems
DE10206173B4 (de) 2002-02-14 2006-08-31 Bruker Daltonik Gmbh Hochauflösende Detektion für Flugzeitmassenspektrometer
EP1766438A2 (en) * 2004-07-01 2007-03-28 Ciphergen Biosystems, Inc. Non-linear signal amplifiers and uses thereof in a mass spectrometer device
US7238936B2 (en) * 2004-07-02 2007-07-03 Thermo Finnigan Llc Detector with increased dynamic range
GB0511332D0 (en) * 2005-06-03 2005-07-13 Micromass Ltd Mass spectrometer
US7423259B2 (en) * 2006-04-27 2008-09-09 Agilent Technologies, Inc. Mass spectrometer and method for enhancing dynamic range
US7501621B2 (en) * 2006-07-12 2009-03-10 Leco Corporation Data acquisition system for a spectrometer using an adaptive threshold
GB0709799D0 (en) * 2007-05-22 2007-06-27 Micromass Ltd Mass spectrometer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3286852B2 (ja) 1992-08-20 2002-05-27 株式会社キーエンス 荷重変化点検出装置の基準変動量設定装置

Also Published As

Publication number Publication date
CA2687420C (en) 2016-09-13
JP2010528280A (ja) 2010-08-19
EP2184763A3 (en) 2010-07-07
GB2457112C (en) 2016-02-03
GB2457112B (en) 2010-02-03
GB0709799D0 (en) 2007-06-27
US8754364B2 (en) 2014-06-17
EP2184763A2 (en) 2010-05-12
WO2008142418A2 (en) 2008-11-27
EP2156460B1 (en) 2013-01-30
CA2687420A1 (en) 2008-11-27
EP2184763B1 (en) 2012-07-18
US20130119247A1 (en) 2013-05-16
WO2008142418A3 (en) 2009-11-05
GB0809338D0 (en) 2008-07-02
US8941056B2 (en) 2015-01-27
EP2434526A1 (en) 2012-03-28
EP2156460A2 (en) 2010-02-24
GB2457112A (en) 2009-08-05
US8354634B2 (en) 2013-01-15
US20100213361A1 (en) 2010-08-26
US20140326867A1 (en) 2014-11-06

Similar Documents

Publication Publication Date Title
JP5528331B2 (ja) イオン検出方法およびイオン検出器システム
JP4921588B2 (ja) 質量分析計
JP5295762B2 (ja) 質量分析計
JP5730291B2 (ja) 質量スペクトルデータを処理する方法
US9324545B2 (en) Calibrating dual ADC acquisition system
JP5059105B2 (ja) 質量分析計

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20110520

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110712

A871 Explanation of circumstances concerning accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A871

Effective date: 20110712

A975 Report on accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A971005

Effective date: 20110726

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110802

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20111031

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20111108

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120202

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120228

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120628

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20120710

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20120802

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20120824

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130625

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130628

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140225

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20140415

R150 Certificate of patent or registration of utility model

Ref document number: 5528331

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250