CA2687420C - Mass spectrometer - Google Patents

Mass spectrometer Download PDF

Info

Publication number
CA2687420C
CA2687420C CA2687420A CA2687420A CA2687420C CA 2687420 C CA2687420 C CA 2687420C CA 2687420 A CA2687420 A CA 2687420A CA 2687420 A CA2687420 A CA 2687420A CA 2687420 C CA2687420 C CA 2687420C
Authority
CA
Canada
Prior art keywords
mass
signal
intensity
digitised
charge ratio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2687420A
Other languages
English (en)
French (fr)
Other versions
CA2687420A1 (en
Inventor
Martin Green
Steven Derek Pringle
Jason Lee Wildgoose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Publication of CA2687420A1 publication Critical patent/CA2687420A1/en
Application granted granted Critical
Publication of CA2687420C publication Critical patent/CA2687420C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/022—Circuit arrangements, e.g. for generating deviation currents or voltages ; Components associated with high voltage supply
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
CA2687420A 2007-05-22 2008-05-22 Mass spectrometer Expired - Fee Related CA2687420C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB0709799.1A GB0709799D0 (en) 2007-05-22 2007-05-22 Mass spectrometer
GB0709799.1 2007-05-22
US94621107P 2007-06-26 2007-06-26
US60/946,211 2007-06-26
PCT/GB2008/001756 WO2008142418A2 (en) 2007-05-22 2008-05-22 Mass spectrometer

Publications (2)

Publication Number Publication Date
CA2687420A1 CA2687420A1 (en) 2008-11-27
CA2687420C true CA2687420C (en) 2016-09-13

Family

ID=38234872

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2687420A Expired - Fee Related CA2687420C (en) 2007-05-22 2008-05-22 Mass spectrometer

Country Status (6)

Country Link
US (3) US8354634B2 (enExample)
EP (3) EP2156460B1 (enExample)
JP (1) JP5528331B2 (enExample)
CA (1) CA2687420C (enExample)
GB (2) GB0709799D0 (enExample)
WO (1) WO2008142418A2 (enExample)

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US9330892B2 (en) 2009-12-31 2016-05-03 Spectro Analytical Instruments Gmbh Simultaneous inorganic mass spectrometer and method of inorganic mass spectrometry
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US8785845B2 (en) * 2010-02-02 2014-07-22 Dh Technologies Development Pte. Ltd. Method and system for operating a time of flight mass spectrometer detection system
GB201002447D0 (en) * 2010-02-12 2010-03-31 Micromass Ltd Mass spectrometer
DE102010011974B4 (de) 2010-03-19 2016-09-15 Bruker Daltonik Gmbh Sättigungskorrektur für Ionensignale in Flugzeitmassenspektrometern
WO2012080443A1 (en) 2010-12-17 2012-06-21 Thermo Fisher Scientific (Bremen) Gmbh Data acquisition system and method for mass spectrometry
GB201106689D0 (en) * 2011-04-20 2011-06-01 Micromass Ltd Function switching with fast asynchronous acquisition
WO2012164378A2 (en) * 2011-06-03 2012-12-06 Dh Technologies Development Pte. Ltd. Removal of ions from survey scans using variable window band-pass filtering to improve intrascan dynamic range
GB201208841D0 (en) 2012-05-18 2012-07-04 Micromass Ltd Calibrating dual adc acquisition system
WO2015004457A1 (en) * 2013-07-09 2015-01-15 Micromass Uk Limited Intelligent dynamic range enhancement
US10354849B2 (en) * 2013-07-09 2019-07-16 Micromass Uk Limited Method of recording ADC saturation
GB201312266D0 (en) * 2013-07-09 2013-08-21 Micromass Ltd Method of recording ADC saturation
DE112015002258B4 (de) * 2014-05-13 2023-09-21 Micromass Uk Limited Mehrdimensionale Ionentrennung
GB201410382D0 (en) * 2014-06-11 2014-07-23 Micromass Ltd Flagging ADC coalescence
DE112015002758T5 (de) 2014-06-11 2017-04-20 Micromass Uk Limited Markieren von ADC-Koaleszenz
GB201514643D0 (en) * 2015-08-18 2015-09-30 Micromass Ltd Mass Spectrometer data acquisition
GB201515357D0 (en) 2015-08-28 2015-10-14 Micromass Ltd Mass spectrometer with digitial step attenuator
GB2544959B (en) * 2015-09-17 2019-06-05 Thermo Fisher Scient Bremen Gmbh Mass spectrometer
US10026598B2 (en) * 2016-01-04 2018-07-17 Rohde & Schwarz Gmbh & Co. Kg Signal amplitude measurement and calibration with an ion trap
CN105609401B (zh) * 2016-02-17 2017-10-24 广州禾信分析仪器有限公司 一种提高飞行时间质谱仪器动态检测范围的方法及系统
US20170263426A1 (en) * 2016-03-10 2017-09-14 Leco Corporation Dynamic Baseline Adjuster
GB201613988D0 (en) 2016-08-16 2016-09-28 Micromass Uk Ltd And Leco Corp Mass analyser having extended flight path
GB201618023D0 (en) 2016-10-25 2016-12-07 Micromass Uk Limited Ion detection system
GB2567794B (en) 2017-05-05 2023-03-08 Micromass Ltd Multi-reflecting time-of-flight mass spectrometers
GB2563571B (en) 2017-05-26 2023-05-24 Micromass Ltd Time of flight mass analyser with spatial focussing
WO2019030471A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov ION GUIDE INSIDE PULSED CONVERTERS
EP3662501A1 (en) 2017-08-06 2020-06-10 Micromass UK Limited Ion mirror for multi-reflecting mass spectrometers
WO2019030473A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov FIELDS FOR SMART REFLECTIVE TOF SM
WO2019030477A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov ACCELERATOR FOR MASS SPECTROMETERS WITH MULTIPASSES
EP3662503A1 (en) 2017-08-06 2020-06-10 Micromass UK Limited Ion injection into multi-pass mass spectrometers
WO2019030474A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov IONIC MIRROR WITH PRINTED CIRCUIT WITH COMPENSATION
US11211238B2 (en) 2017-08-06 2021-12-28 Micromass Uk Limited Multi-pass mass spectrometer
GB201806507D0 (en) 2018-04-20 2018-06-06 Verenchikov Anatoly Gridless ion mirrors with smooth fields
GB201807626D0 (en) 2018-05-10 2018-06-27 Micromass Ltd Multi-reflecting time of flight mass analyser
GB201807605D0 (en) 2018-05-10 2018-06-27 Micromass Ltd Multi-reflecting time of flight mass analyser
GB201808530D0 (en) 2018-05-24 2018-07-11 Verenchikov Anatoly TOF MS detection system with improved dynamic range
GB201810573D0 (en) 2018-06-28 2018-08-15 Verenchikov Anatoly Multi-pass mass spectrometer with improved duty cycle
GB201901411D0 (en) 2019-02-01 2019-03-20 Micromass Ltd Electrode assembly for mass spectrometer
GB201903779D0 (en) 2019-03-20 2019-05-01 Micromass Ltd Multiplexed time of flight mass spectrometer
GB202110412D0 (en) * 2021-07-20 2021-09-01 Micromass Ltd Mass spectrometer for generating and summing mass spectral data
WO2024161624A1 (ja) * 2023-02-03 2024-08-08 株式会社島津製作所 質量分析方法及び質量分析装置
CN116593569B (zh) * 2023-05-18 2025-10-28 北京清谱科技有限公司 一种拓展检测器动态范围的方法、装置及电子设备
WO2025144683A1 (en) * 2023-12-28 2025-07-03 Intabio, Llc External ion source spatial positioning analysis
US20250322913A1 (en) * 2024-04-11 2025-10-16 MOBILion Systems, Inc. Systems and Methods for Enhanced Acquisition of Mass Spectrometry Data

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JPH09184823A (ja) * 1995-12-28 1997-07-15 Shimadzu Corp 分析装置の検出信号処理装置
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US6195031B1 (en) * 1998-12-28 2001-02-27 Siemens Aktiengesellschaft Analog-to-digital converter with level converter and level recognition unit and correction memory
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US7038197B2 (en) * 2001-04-03 2006-05-02 Micromass Limited Mass spectrometer and method of mass spectrometry
EP1405055A4 (en) 2001-05-25 2007-05-23 Analytica Of Branford Inc MULTIPLE DETECTTON SYSTEM
DE10206173B4 (de) 2002-02-14 2006-08-31 Bruker Daltonik Gmbh Hochauflösende Detektion für Flugzeitmassenspektrometer
CA2571206A1 (en) * 2004-07-01 2006-01-19 Ciphergen Biosystems, Inc. Non-linear signal amplifiers and uses thereof in a mass spectrometer device
US7238936B2 (en) * 2004-07-02 2007-07-03 Thermo Finnigan Llc Detector with increased dynamic range
GB0511332D0 (en) * 2005-06-03 2005-07-13 Micromass Ltd Mass spectrometer
US7423259B2 (en) 2006-04-27 2008-09-09 Agilent Technologies, Inc. Mass spectrometer and method for enhancing dynamic range
US7501621B2 (en) * 2006-07-12 2009-03-10 Leco Corporation Data acquisition system for a spectrometer using an adaptive threshold
GB0709799D0 (en) * 2007-05-22 2007-06-27 Micromass Ltd Mass spectrometer

Also Published As

Publication number Publication date
US20140326867A1 (en) 2014-11-06
EP2184763A2 (en) 2010-05-12
US20130119247A1 (en) 2013-05-16
US8941056B2 (en) 2015-01-27
CA2687420A1 (en) 2008-11-27
EP2156460A2 (en) 2010-02-24
US8754364B2 (en) 2014-06-17
GB2457112C (en) 2016-02-03
GB2457112A (en) 2009-08-05
JP2010528280A (ja) 2010-08-19
EP2434526A1 (en) 2012-03-28
EP2184763B1 (en) 2012-07-18
GB2457112B (en) 2010-02-03
JP5528331B2 (ja) 2014-06-25
WO2008142418A3 (en) 2009-11-05
GB0709799D0 (en) 2007-06-27
EP2184763A3 (en) 2010-07-07
US20100213361A1 (en) 2010-08-26
GB0809338D0 (en) 2008-07-02
US8354634B2 (en) 2013-01-15
WO2008142418A2 (en) 2008-11-27
EP2156460B1 (en) 2013-01-30

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Effective date: 20130521

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