JP5522635B2 - 血液適合性、及び/又は治癒促進性を有する上塗りを備えた、薬物溶出性の埋込型医療デバイス - Google Patents

血液適合性、及び/又は治癒促進性を有する上塗りを備えた、薬物溶出性の埋込型医療デバイス Download PDF

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JP5522635B2
JP5522635B2 JP2010518261A JP2010518261A JP5522635B2 JP 5522635 B2 JP5522635 B2 JP 5522635B2 JP 2010518261 A JP2010518261 A JP 2010518261A JP 2010518261 A JP2010518261 A JP 2010518261A JP 5522635 B2 JP5522635 B2 JP 5522635B2
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lactide
drug
layer
implantable medical
medical device
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JP2010534513A5 (enExample
JP2010534513A (ja
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ローター, ウォルター クライナー,
イーウェン タン,
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アボット カーディオヴァスキュラー システムズ インコーポレイテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M25/0045Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • A61L2300/608Coatings having two or more layers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00Materials or methods for coatings medical devices
    • A61L2420/08Coatings comprising two or more layers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2010518261A 2007-07-27 2008-06-30 血液適合性、及び/又は治癒促進性を有する上塗りを備えた、薬物溶出性の埋込型医療デバイス Expired - Fee Related JP5522635B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/881,668 2007-07-27
US11/881,668 US8182829B2 (en) 2007-07-27 2007-07-27 Drug eluting implantable medical device with hemocompatible and/or prohealing topcoat
PCT/US2008/068850 WO2009017924A2 (en) 2007-07-27 2008-06-30 Drug eluting implantable medical device with hemocompatible and/or prohealing topcoat

Publications (3)

Publication Number Publication Date
JP2010534513A JP2010534513A (ja) 2010-11-11
JP2010534513A5 JP2010534513A5 (enExample) 2011-07-07
JP5522635B2 true JP5522635B2 (ja) 2014-06-18

Family

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Family Applications (1)

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JP2010518261A Expired - Fee Related JP5522635B2 (ja) 2007-07-27 2008-06-30 血液適合性、及び/又は治癒促進性を有する上塗りを備えた、薬物溶出性の埋込型医療デバイス

Country Status (5)

Country Link
US (5) US8182829B2 (enExample)
EP (2) EP3053606A1 (enExample)
JP (1) JP5522635B2 (enExample)
ES (1) ES2576636T3 (enExample)
WO (1) WO2009017924A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8685430B1 (en) 2006-07-14 2014-04-01 Abbott Cardiovascular Systems Inc. Tailored aliphatic polyesters for stent coatings
US20090228097A1 (en) * 2008-03-07 2009-09-10 Abbott Cardiovascular Systems Inc. A1 Adenosine Receptor Antagonist-Coated Implantable Medical Device
US20090299466A1 (en) * 2008-06-02 2009-12-03 Medtronic Vascular, Inc. Local Delivery of Matrix Metalloproteinase Inhibitors
EP2367505B1 (en) 2008-09-29 2020-08-12 Edwards Lifesciences CardiAQ LLC Heart valve
EP2845569A1 (en) 2008-10-01 2015-03-11 Cardiaq Valve Technologies, Inc. Delivery system for vascular implant
US8668919B2 (en) * 2009-03-03 2014-03-11 Abbott Cardiovascular Systems Inc. Polymer for creating hemocompatible surface
US9492587B2 (en) * 2009-04-13 2016-11-15 Abbott Cardiovascular Systems Inc. Stent made from an ultra high molecular weight bioabsorbable polymer with high fatigue and fracture resistance
WO2010121076A2 (en) 2009-04-15 2010-10-21 Cardiaq Valve Technologies, Inc. Vascular implant and delivery system
US8685433B2 (en) * 2010-03-31 2014-04-01 Abbott Cardiovascular Systems Inc. Absorbable coating for implantable device
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
DE102010041341A1 (de) * 2010-09-24 2012-03-29 Universität Rostock Ohrimplantat und Stimulationselektrode für ein Ohrimplantat
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US10583002B2 (en) 2013-03-11 2020-03-10 Neovasc Tiara Inc. Prosthetic valve with anti-pivoting mechanism
US9681951B2 (en) 2013-03-14 2017-06-20 Edwards Lifesciences Cardiaq Llc Prosthesis with outer skirt and anchors
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
US12049640B2 (en) * 2018-03-15 2024-07-30 Toray Industries, Inc. Cell adhesive material
US11931485B2 (en) * 2021-01-13 2024-03-19 Adnan I. Qureshi Implantable sustained release device and a method of use therefor in the treatment of brain disorders
CN115845151A (zh) * 2021-09-24 2023-03-28 王浩 一种亲水超滑的医用导管

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485227A (en) 1983-06-16 1984-11-27 Howmedica, Inc. Biocompatible poly-(ether-urethane-urea) and process for its preparation
US5477864A (en) 1989-12-21 1995-12-26 Smith & Nephew Richards, Inc. Cardiovascular guidewire of enhanced biocompatibility
US6284854B1 (en) 1991-07-05 2001-09-04 Biccompatibles Limited Polymeric surface coatings
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6890546B2 (en) * 1998-09-24 2005-05-10 Abbott Laboratories Medical devices containing rapamycin analogs
US6153252A (en) * 1998-06-30 2000-11-28 Ethicon, Inc. Process for coating stents
US20060093771A1 (en) * 2002-02-15 2006-05-04 Frantisek Rypacek Polymer coating for medical devices
US7629049B2 (en) 2002-10-18 2009-12-08 Medasorb, Inc. Hemocompatible polymer systems and related devices
US6884829B2 (en) 2002-10-18 2005-04-26 Robert L. Albright Hemocompatible coated polymer and related one-step methods
US7491234B2 (en) * 2002-12-03 2009-02-17 Boston Scientific Scimed, Inc. Medical devices for delivery of therapeutic agents
US7709439B2 (en) * 2004-02-20 2010-05-04 Boston Scientific Scimed, Inc. Biomaterials for enhanced healing
US20060088571A1 (en) 2004-10-21 2006-04-27 Medtronic Vascular, Inc. Biocompatible and hemocompatible polymer compositions
US8007775B2 (en) * 2004-12-30 2011-08-30 Advanced Cardiovascular Systems, Inc. Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same
US20060172895A1 (en) * 2005-02-02 2006-08-03 Halliburton Energy Services, Inc. Degradable particulate generation and associated methods
US8663673B2 (en) 2005-07-29 2014-03-04 Surmodics, Inc. Devices, articles, coatings, and methods for controlled active agent release or hemocompatibility
JP2009505726A (ja) 2005-08-25 2009-02-12 メドトロニック ヴァスキュラー インコーポレイテッド 生分解性ポリマーを含むことにより向上した官能性を有する医療機器及びコーティング
US20070149640A1 (en) * 2005-12-28 2007-06-28 Sasa Andjelic Bioabsorbable polymer compositions exhibiting enhanced crystallization and hydrolysis rates
US20070212387A1 (en) 2006-03-08 2007-09-13 Sahajanand Medical Technologies Pvt. Ltd. Coatings for implantable medical devices

Also Published As

Publication number Publication date
EP3053606A8 (en) 2016-10-05
US8545868B2 (en) 2013-10-01
US20090030505A1 (en) 2009-01-29
US8357390B2 (en) 2013-01-22
EP2185213A2 (en) 2010-05-19
EP2185213B1 (en) 2016-03-30
EP3053606A1 (en) 2016-08-10
US20120209371A1 (en) 2012-08-16
US20120209372A1 (en) 2012-08-16
JP2010534513A (ja) 2010-11-11
ES2576636T3 (es) 2016-07-08
US20140031919A1 (en) 2014-01-30
US8182829B2 (en) 2012-05-22
WO2009017924A3 (en) 2010-03-11
US20130178832A1 (en) 2013-07-11
WO2009017924A2 (en) 2009-02-05

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