JP5475419B2 - Redness unevenness improver - Google Patents
Redness unevenness improver Download PDFInfo
- Publication number
- JP5475419B2 JP5475419B2 JP2009275860A JP2009275860A JP5475419B2 JP 5475419 B2 JP5475419 B2 JP 5475419B2 JP 2009275860 A JP2009275860 A JP 2009275860A JP 2009275860 A JP2009275860 A JP 2009275860A JP 5475419 B2 JP5475419 B2 JP 5475419B2
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- JP
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- Prior art keywords
- extract
- mass
- skin
- component
- redness
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Landscapes
- Cosmetics (AREA)
Description
本発明は、赤みムラ改善剤に関する。 The present invention relates to a redness unevenness improving agent.
エイジングケアを目的としたスキンケア化粧料のカテゴリーの1つに美白化粧料がある。この美白化粧料は、一般的にはシミやソバカスなど日光曝露による刺激やホルモンの異常又は遺伝的要素によりメラノサイトが活性化され、その結果メラノサイトで合成されたメラニン色素が皮膚内に異常沈着することを予防または改善するものである。このようなシミ・ソバカスの予防・改善には、従来、トラネキサム酸およびその誘導体、ハイドロキノン誘導体、あるいは油溶性カミツレ抽出物等のメラニン生成抑制効果を有する成分を配合した美白化粧料が使用されている(たとえば、特許文献1〜3参照)。 One of the categories of skin care cosmetics intended for aging care is whitening cosmetics. In this whitening cosmetic, in general, melanocytes are activated by irritation caused by exposure to sunlight such as spots and buckwheat, hormonal abnormalities, or genetic elements, and as a result, melanin pigments synthesized in melanocytes are abnormally deposited in the skin. Is to prevent or improve. For the prevention and improvement of such spots and freckles, whitening cosmetics containing ingredients having an inhibitory effect on melanin production such as tranexamic acid and its derivatives, hydroquinone derivatives, or oil-soluble chamomile extract have been used. (For example, refer to Patent Documents 1 to 3).
しかしながら、上述した特許文献1〜3に開示された美白化粧料はメラニン色素の異常沈着を防止できるものの、消費者が実感する美肌感の一つである素肌が明るくなる効果を得ることが難しかった。 However, although the whitening cosmetics disclosed in Patent Documents 1 to 3 described above can prevent abnormal deposition of melanin pigment, it is difficult to obtain an effect of brightening the skin, which is one of the beautiful skin feelings that consumers feel. .
本発明者らは、被験者の素肌の色を解析した結果、人の素肌にはメラニン由来の色素沈着だけでなく、ヘモグロビン色素由来の赤みムラも存在していることがわかった。
本発明者らは、特開2002-200050号公報に開示されている画像処理装置を用いて、被験者の1枚の顔画像から被験者の素肌の色をメラニン色素由来の色みとヘモグロビン色素由来の色みとに分解した2枚の顔画像を得た。ヘモグロビン色素由来の色みを有する顔画像を観察すると、画像に色みムラがあることを見出した。この色みムラに係る成分をシミュレーションにより取り除き、この画像と先に得たメラニン色素由来の画像と重ね合わせた合成画像を被験者らに閲覧させると、元の画像よりも素肌が明るくなったという美肌感を感じることがわかった。すなわち、素肌が明るくなるという美肌感を得るためには、メラニン色素由来の黒みムラだけでなく、ヘモグロビン色素由来の赤みムラを改善させることが重要であることがわかった。この結果に基づき、本発明者らは、素肌のヘモグロビン色素由来の赤みムラを改善させる剤について種々の検討を行った結果、アスナロ抽出物とキキョウ抽出物とを組み合わせることで、皮膚に存在している赤みムラが改善していくことを見出した。
As a result of analyzing the color of the skin of the subject, the present inventors have found that not only pigmentation derived from melanin but also redness unevenness derived from hemoglobin pigment exist in human skin.
Using the image processing device disclosed in Japanese Patent Application Laid-Open No. 2002-200050, the present inventors have obtained the color of the subject's bare skin from the color image derived from the melanin and the hemoglobin pigment from one face image of the subject. Two face images separated into color were obtained. When a face image having a color derived from a hemoglobin pigment was observed, it was found that the image had color unevenness. By removing the components related to this color unevenness by simulation and allowing the subjects to view a composite image obtained by superimposing this image and the previously obtained melanin pigment-derived image, the skin becomes brighter than the original image I understood that I felt a feeling. That is, in order to obtain a beautiful skin feeling that the skin becomes bright, it has been found that it is important to improve not only the melanin-derived blackness unevenness but also the hemoglobin pigment-derived redness unevenness. Based on this result, the present inventors have conducted various studies on agents that improve the redness unevenness derived from the hemoglobin pigment of the bare skin, and as a result, the combination of Asunaro extract and Kyoko extract is present in the skin. I found that the unevenness of redness is improving.
すなわち、本発明によれば、(A)アスナロ抽出物、(B)キキョウ抽出物を有効成分とする赤みムラ改善剤が提供される。
さらに、本発明によれば、上述した(A)アスナロ抽出物、(B)キキョウ抽出物を含む皮膚化粧料も提供することができる。
That is, according to this invention, the redness nonuniformity improving agent which uses (A) Asunaro extract and (B) Kyoko extract as an active ingredient is provided.
Furthermore, according to this invention, the skin cosmetics containing the (A) Asunaro extract mentioned above and (B) Kyodo extract can also be provided.
本発明は、皮膚の赤みムラを改善する赤みムラ改善剤を提供するものである。更には、皮膚の赤みムラを改善し、素肌が明るくなるという美肌感を得ることができる皮膚化粧料が提供される。 The present invention provides a redness unevenness improving agent that improves redness unevenness of the skin. Furthermore, a skin cosmetic that can improve skin redness unevenness and provide a beautiful skin feeling that the skin becomes brighter is provided.
以下、本発明の実施形態を説明する。
(赤みムラ改善剤)
本発明の赤みムラ改善剤は、(A)アスナロ抽出物、(B)キキョウ抽出物を有効成分として含む。
このような赤みムラ改善剤は、皮膚(頭皮を除く)に塗布することで、ヘモグロビン色素由来の皮膚の赤みムラを改善し、結果として素肌を明るくさせることができ、美肌感を得ることができる。
人の素肌の色は、前述したように、大まかにメラニン色素由来の黒み成分と、ヘモグロビン色素由来の赤み成分により構成されると考える。この黒み成分と赤み成分は、特開2002−200050号の装置により分解され、赤み成分として独立した画像として表示することが出来る。この結果、人の素肌の赤み成分の分布を目視で観察することができ、素肌がくすんでいると感じていた被験者の顔画像をみると、赤み成分は、均一なものではなく、部分的に濃淡が存在することがわかった。
赤みムラとはヘモグロビンの分布状態により生じる部分的な濃淡に由来するものである。赤みムラの発生する原因は、血流の状態、皮膚の厚みなどさまざまであると考えられる。
メラニン由来の黒みムラの改善には、美白剤が知られている。これは、メラニンの生成を抑えたあと、メラニンを含む細胞がターンオーバーにより皮膚外に垢となって排出させる必要があり、一般的に少なくとも4週間以上はかかってしまう。一方で、ヘモグロビン色素由来の赤みムラは基底層直下のヘモグロビンの分布状態をコントロールする、或いは、表皮、真皮の状態を改善すればよく、ターンオーバーとは直接関係なく改善させることができるので、比較的短期に改善効果を生み出すことが期待できる。従って、本発明の赤みムラ改善剤は、赤みムラを改善するため、比較的短期間で素肌が明るくなるという美肌感を得ることが可能となる。
なお、赤みムラ改善剤は、ヘモグロビン色素由来の皮膚の赤みムラ(赤みの濃淡のある不均一な状態)を改善するものであり、皮膚の炎症を抑制する抗炎症効果とは異なるものである。
Embodiments of the present invention will be described below.
(Redness unevenness improver)
The redness unevenness improving agent of the present invention contains (A) an asunalo extract and (B) a red pepper extract as active ingredients.
By applying such a redness unevenness improving agent to the skin (excluding the scalp), the redness unevenness of the skin derived from the hemoglobin pigment can be improved, and as a result, the skin can be brightened and a beautiful skin feel can be obtained. .
As described above, the color of human skin is roughly composed of a dark component derived from a melanin pigment and a red component derived from a hemoglobin pigment. The black component and the red component are decomposed by an apparatus disclosed in JP-A-2002-200050, and can be displayed as an independent image as a red component. As a result, it is possible to visually observe the distribution of the redness component of the human skin, and when looking at the face image of the subject who felt that the skin was dull, the redness component was not uniform and partially It was found that there was a shading.
Redness unevenness is derived from partial shading caused by the distribution state of hemoglobin. The cause of the occurrence of redness unevenness is considered to be various, such as the state of blood flow and the thickness of the skin.
A whitening agent is known for the improvement of melanin-derived blackness unevenness. This is because, after suppressing the production of melanin, cells containing melanin need to be removed from the skin as dirt by turnover, and generally takes at least 4 weeks. On the other hand, the redness unevenness derived from the hemoglobin pigment can control the distribution of hemoglobin directly under the basal layer, or improve the state of the epidermis and dermis, and can be improved regardless of the turnover. It can be expected to produce improvement effects in the short term. Therefore, since the redness unevenness improving agent of the present invention improves redness unevenness, it is possible to obtain a beautiful skin feeling that the skin becomes bright in a relatively short period of time.
The redness unevenness-improving agent improves the redness unevenness of the skin derived from the hemoglobin pigment (a non-uniform state with reddish shades) and is different from the anti-inflammatory effect that suppresses skin inflammation.
(成分(A))
成分(A)のアスナロ抽出物は、ヒノキ科(Cupressaceae)、アスナロ属(Thujopsis)のアスナロ(Thujopsis dolabrata)から得られる抽出物である。アスナロは、全体又は葉部、小枝部、根部、幹部等のいずれの部位も用いることができるが、葉部又は小枝部(花実、毬果も含む)が特に好ましい。
(Ingredient (A))
The asunalo extract of component (A) is an extract obtained from the Cupressaceae, Thujopsis dolabrata. Asunaro can be used as a whole or any part such as a leaf part, a twig part, a root part, a trunk part, etc., but a leaf part or a twig part (including flower seeds and fruits) is particularly preferable.
抽出に用いる溶剤としては、例えば、水;石油エーテル、n−ヘキサン、シクロヘキサン、トルエン、ベンゼン等の炭化水素類;ジクロロメタン、クロロホルム、四塩化炭素等のハロゲン化炭化水素類;テトラヒドロフラン、ジエチルエーテル等のエーテル類;酢酸メチル、酢酸エチル等のエステル類;アセトン、メチルエチルケトン等のケトン類;ピリジン類;ブタノール、プロパノール、エタノール、メタノール、ポリエチレングリコール(分子量1000以下)、プロピレングリコール、ブチレングリコール等の一価又は多価アルコール類などが挙げられ、これらを1種又は2種以上混合して用いることができる。これらのうち、水、一価アルコール及び多価アルコールから選ばれる1種又は2種以上が好ましく、特に、水及び/又はエタノールが最も好ましい。 Examples of the solvent used for extraction include water; hydrocarbons such as petroleum ether, n-hexane, cyclohexane, toluene, and benzene; halogenated hydrocarbons such as dichloromethane, chloroform, and carbon tetrachloride; tetrahydrofuran, diethyl ether, and the like. Ethers; Esters such as methyl acetate and ethyl acetate; Ketones such as acetone and methyl ethyl ketone; Pyridines; Monovalent such as butanol, propanol, ethanol, methanol, polyethylene glycol (molecular weight 1000 or less), propylene glycol, butylene glycol, etc. Examples thereof include polyhydric alcohols, and these can be used alone or in combination of two or more. Of these, one or more selected from water, monohydric alcohols and polyhydric alcohols are preferred, with water and / or ethanol being most preferred.
本発明に用いる抽出物は、例えば、アスナロまたはアスナロを乾燥もしくは乾燥することなく裁断、粉砕等したものを上記溶媒を用いて抽出し、適宜希釈、濃縮、又は凍結乾燥等を行うことにより得ることができる。 The extract used in the present invention can be obtained by, for example, extracting asnalo or a product obtained by cutting or crushing asnalo without drying or drying using the above solvent, and appropriately diluting, concentrating, lyophilizing, or the like. Can do.
成分(A)の含有量は、赤みムラ改善剤全体に対し、0.0025質量%以上、0.02質量%以下であることが好ましい。0.0025質量%以上含有させ、さらにキキョウ抽出物と合わせることで赤みムラに対する効果が確実に発揮される。また、0.02質量%以下とすることで使用感を損なわず、安定性が維持できる。なかでも、成分(A)の含有量は、赤みムラ改善剤全体に対し、0.005質量%以上、0.0175質量%以下、さらには、0.0075質量%以上、0.015質量%以下であることが好ましい。 It is preferable that content of a component (A) is 0.0025 mass% or more and 0.02 mass% or less with respect to the whole redness nonuniformity improving agent. By containing 0.0025% by mass or more and further combining with Kyoko extract, the effect on unevenness of redness is reliably exhibited. Moreover, stability can be maintained, without impairing usability by setting it as 0.02 mass% or less. Especially, it is preferable that content of a component (A) is 0.005 mass% or more and 0.0175 mass% or less with respect to the whole redness nonuniformity improving agent, Furthermore, 0.0075 mass% or more and 0.015 mass% or less.
(成分(B))
成分(B)キキョウ抽出物は、キキョウ(Platycodon grandiflorum A. De Candolle(キキョウ科))から得られる抽出物である。キキョウは、全体又は葉部、小枝部、根部、幹部等のいずれの部位も用いることができるが、根部が特に好ましい。
抽出に用いられる溶剤としては、成分(A)で述べたものと同様のものを使用することができる。
本発明に用いる抽出物は、例えば、キキョウを乾燥もしくは乾燥することなく裁断、粉砕等したものを上記溶媒を用いて抽出し、適宜希釈、濃縮、又は凍結乾燥等を行うことにより得ることができる。
(Ingredient (B))
Ingredient (B) Kyokyo extract is an extract obtained from Kyoyou (Platycodon grandiflorum A. De Candolle). As for Scotch, the whole or any part such as a leaf part, a twig part, a root part or a trunk part can be used, but the root part is particularly preferable.
As the solvent used for extraction, the same solvents as those described for the component (A) can be used.
The extract used in the present invention can be obtained, for example, by extracting, using the above-mentioned solvent, cutting, pulverizing, or the like without drying or drying kyoto and appropriately diluting, concentrating, lyophilizing, or the like. .
成分(B)の含有量は、赤みムラ改善剤全体に対し、0.025質量%以上、0.25質量%以下であることが好ましい。0.025質量%以上含有させ、さらにアスナロ抽出物と合わせることで赤みムラに対する効果が確実に発揮される。また、0.25質量%以下とすることで使用感を損なわず、安定性が維持できる。なかでも、成分(B)の含有量は、赤みムラ改善剤全体に対し、0.075質量%以上、0.2質量%以下、さらには、0.1質量%以上、0.2質量%以下であることが好ましい。
成分(A)および成分(B)は、上述した量を含むものであるが、前記成分(A)と、前記成分(B)との質量比である(A)/(B)が0.001以上、1.0以下であることが好ましい。なかでも、(A)/(B)が0.02以上、さらには、0.06以上であることが好ましく、(A)/(B)が0.5以下、さらには、0.25以下、とくには0.2以下であることが好ましい。
(A)/(B)を0.001以上とすることで、赤みムラ改善効果があらわれはじめることを確実に実感できるという効果があり、(A)/(B)を1.0以下とすることで、赤みムラ改善効果を確実に発揮させることができる。
It is preferable that content of a component (B) is 0.025 mass% or more and 0.25 mass% or less with respect to the whole redness nonuniformity improving agent. By containing 0.025% by mass or more and further combining with an asunalo extract, the effect on unevenness in redness is reliably exhibited. Moreover, stability is maintainable without impairing usability by setting it as 0.25 mass% or less. Especially, it is preferable that content of a component (B) is 0.075 mass% or more and 0.2 mass% or less with respect to the whole redness nonuniformity improving agent, Furthermore, 0.1 mass% or more and 0.2 mass% or less.
The component (A) and the component (B) include the above-described amounts, and (A) / (B), which is a mass ratio of the component (A) and the component (B), is 0.001 or more. It is preferable that it is 1.0 or less. Among these, (A) / (B) is preferably 0.02 or more, more preferably 0.06 or more, and (A) / (B) is 0.5 or less, further 0.25 or less, In particular, it is preferably 0.2 or less.
By setting (A) / (B) to 0.001 or more, there is an effect that the effect of improving redness unevenness can be surely realized, and (A) / (B) is set to 1.0 or less. Thus, the effect of improving redness unevenness can be surely exhibited.
以上のような赤みムラ改善剤は、成分(A)および成分(B)を含むものであればよいが、たとえば、水中に、成分(A)又は成分(A)と成分(A)の抽出溶媒を含むアスナロエキス、成分(B)又は成分(B)と成分(B)の抽出溶媒を含むキキョウエキスとを混合することで得られる。 The redness unevenness improving agent as described above may contain the component (A) and the component (B). For example, the extraction solvent for the component (A) or the component (A) and the component (A) in water. It can be obtained by mixing the asunalo extract containing, component (B) or component (B) and a kyoukyo extract containing the extraction solvent for component (B).
(皮膚化粧料)
本発明の皮膚化粧料は、上述した成分(A)および成分(B)を含む皮膚化粧料である。
この皮膚化粧料は、皮膚(頭皮を除く)に塗布されるものである。
成分(A)の含有量は、皮膚化粧料全体に対し、0.0025質量%以上、0.02質量%以下であることが好ましい。0.0025質量%以上含有させ、さらにキキョウ抽出物と合わせることで赤みムラに対する効果が確実に発揮される。また、0.02質量%以下とすることで使用感を損なわず、安定性が維持できる。なかでも、成分(A)の含有量は、皮膚化粧料全体に対し、0.005質量%以上、0.0175質量%以下、さらには、0.0075質量%以上、0.015質量%以下であることが好ましい。
成分(B)の含有量は、皮膚化粧料全体に対し、0.025質量%以上、0.25質量%以下であることが好ましい。0.025質量%以上含有させ、さらにアスナロ抽出物と合わせることで赤みムラに対する効果が確実に発揮される。また、0.25質量%以下とすることで使用感を損なわず、安定性が維持できる。なかでも、成分(B)の含有量は、皮膚化粧料全体に対し、0.075質量%以上、0.2質量%以下、さらには、0.1質量%以上、0.2質量%以下であることが好ましい。
成分(A)および成分(B)は、上述した量を含むものであるが、前記成分(A)と、前記成分(B)との質量比である(A)/(B)が0.001以上、1.0以下であることが好ましい。なかでも、(A)/(B)が0.02以上、さらには、0.06以上であることが好ましく、(A)/(B)が0.5以下、さらには、0.25以下、とくには0.2以下であることが好ましい。
(A)/(B)を0.001以上とすることで、赤みムラ改善効果があらわれはじめることを確実に実感できるという効果があり、(A)/(B)を1.0以下とすることで、赤みムラ改善効果を確実に発揮させることができる。
皮膚化粧料は、上述した赤みムラ改善剤以外に、更に、美白有効成分、保湿剤、油剤、界面活性剤、水溶性高分子を含んでいてもよい。
(Skin cosmetic)
The skin cosmetic of the present invention is a skin cosmetic containing the component (A) and the component (B) described above.
This skin cosmetic is applied to the skin (excluding the scalp).
It is preferable that content of a component (A) is 0.0025 mass% or more and 0.02 mass% or less with respect to the whole skin cosmetics. By containing 0.0025% by mass or more and further combining with Kyoko extract, the effect on unevenness of redness is reliably exhibited. Moreover, stability can be maintained, without impairing usability by setting it as 0.02 mass% or less. Especially, it is preferable that content of a component (A) is 0.005 mass% or more and 0.0175 mass% or less with respect to the whole skin cosmetics, Furthermore, 0.0075 mass% or more and 0.015 mass% or less.
It is preferable that content of a component (B) is 0.025 mass% or more and 0.25 mass% or less with respect to the whole skin cosmetics. By containing 0.025% by mass or more and further combining with an asunalo extract, the effect on unevenness in redness is reliably exhibited. Moreover, stability is maintainable without impairing usability by setting it as 0.25 mass% or less. Especially, it is preferable that content of a component (B) is 0.075 mass% or more and 0.2 mass% or less with respect to the whole skin cosmetics, Furthermore, 0.1 mass% or more and 0.2 mass% or less.
The component (A) and the component (B) include the above-described amounts, and (A) / (B), which is a mass ratio of the component (A) and the component (B), is 0.001 or more. It is preferable that it is 1.0 or less. Among these, (A) / (B) is preferably 0.02 or more, more preferably 0.06 or more, and (A) / (B) is 0.5 or less, further 0.25 or less, In particular, it is preferably 0.2 or less.
By setting (A) / (B) to 0.001 or more, there is an effect that the effect of improving redness unevenness can be surely realized, and (A) / (B) is set to 1.0 or less. Thus, the effect of improving redness unevenness can be surely exhibited.
The skin cosmetic may further contain a whitening active ingredient, a moisturizing agent, an oil agent, a surfactant, and a water-soluble polymer in addition to the above-described redness unevenness improving agent.
(美白有効成分)
美白の化合物としては、例えば、ビタミンC及びその誘導体、アルブチン、エラグ酸、コハク酸、リノール酸、トラネキサム酸、2,4レゾルシノール誘導体、サリチル酸、アスコルビン酸またはその誘導体、ハイドロキノン及びその誘導体が挙げられる。これらのなかから1種以上を含むことが好ましく、また、美白効果や安定性の観点から、0.1〜5質量%含むことが好ましい。
美白効果のある植物エキスとしては、例えば、カミツレエキス、バラエキス、オノニスエキス、アセンヤクエキス、パリエタリアエキス、アンソッコウエキス、サボンソウエキス、クロレラエキス、ユーカリエキス、アロエエキス、リョクチャエキス、カッコンエキス、アロエエキス、チョウジエキス、ワレモコウエキス、マロニエ樹皮エキス、アダパレン、リンゴエキス、クララエキス、シラカバエキス、クワエキスが挙げられる。これらのなかから1種以上を含むことが好ましく、また、美白効果や安定性の観点から、抽出物としては、0.0025〜0.25質量%含むことが好ましい。
特に、ビタミンC及びその誘導体、トラネキサム酸、カミツレエキスが美肌感が早く現れる点で好ましく、これらのなかから美白成分として1種以上を含むことが好ましい。
(Whitening active ingredient)
Examples of the whitening compound include vitamin C and its derivatives, arbutin, ellagic acid, succinic acid, linoleic acid, tranexamic acid, 2,4 resorcinol derivatives, salicylic acid, ascorbic acid or derivatives thereof, hydroquinone and derivatives thereof. Among these, it is preferable to include one or more, and from the viewpoint of whitening effect and stability, it is preferable to include 0.1 to 5% by mass.
Examples of plant extracts that have a whitening effect include chamomile extract, rose extract, onionis extract, papaver extract, parietalia extract, anthony extract, savory extract, chlorella extract, eucalyptus extract, aloe extract, ryokcha extract, cuckoo extract, aloe Examples include extract, clove extract, bitumen extract, marronnier bark extract, adapalene, apple extract, clara extract, birch extract, mulberry extract. Among these, it is preferable to contain one or more kinds, and from the viewpoint of whitening effect and stability, the extract preferably contains 0.0025 to 0.25% by mass.
In particular, vitamin C and its derivatives, tranexamic acid, and chamomile extract are preferable in terms of early appearance of a beautiful skin, and among these, it is preferable to include one or more as a whitening component.
(保湿剤)
保湿剤としては、皮膚化粧料に配合できるものであればどのようなものでもよいが、例えば、エチレングリコール、プロピレングリコール、1,3−ブチレングリコール、ジエチレングリコール、ジプロピレングリコール、トリエチレングリコール、ヘキシレングリコール、ポリエチレングリコール、エトキシジグリコールグリセリン等の多価アルコールやタンパク質、ムコ多糖、コラーゲン、エラスチン、ベタイン、ヒアルロン酸が挙げられる。
これらのなかから保湿成分として1種以上を含むことが好ましく、また、保湿やべたつきの観点から、1〜5質量%含むことが好ましい。
(Humectant)
Any moisturizing agent may be used as long as it can be incorporated into skin cosmetics. For example, ethylene glycol, propylene glycol, 1,3-butylene glycol, diethylene glycol, dipropylene glycol, triethylene glycol, hexylene. Examples include polyhydric alcohols such as glycol, polyethylene glycol, and ethoxydiglycol glycerin, proteins, mucopolysaccharides, collagen, elastin, betaine, and hyaluronic acid.
Among these, it is preferable to include one or more kinds as a moisturizing component, and it is preferable to include 1 to 5% by mass from the viewpoint of moisturizing and stickiness.
(油剤)
油剤としては、皮膚化粧料に配合できるものであればどのようなものでもよいが、例えば流動パラフィン、ワセリン、パラフィンワックス、スクワラン、ミツロウ、カルナウバロウ、オリーブ油、ラノリン、高級アルコール、脂肪酸、高級アルコールと脂肪酸の合成エステル油、シリコーン油等が挙げられ、これらの中で流動パラフィンが好ましい。
また、保湿やべたつきの観点から、1〜5質量%含むことが好ましい。
(Oil)
Any oil can be used as long as it can be incorporated into skin cosmetics. For example, liquid paraffin, petrolatum, paraffin wax, squalane, beeswax, carnauba wax, olive oil, lanolin, higher alcohol, fatty acid, higher alcohol and fatty acid. Synthetic ester oils, silicone oils, and the like, and liquid paraffin is preferable among them.
Moreover, it is preferable to contain 1-5 mass% from a viewpoint of moisture retention or stickiness.
(界面活性剤)
界面活性剤としては、皮膚化粧料に一般に用いられている界面活性剤であればよく、例えばポリオキシエチレンアルキルエーテル、ポリオキシエチレン脂肪酸エステル、ポリオキシエチレンソルビタン脂肪酸エステル、グリセリン脂肪酸エステル、ポリグリセリン脂肪酸エステル、ポリオキシエチレングリセリン脂肪酸エステル、ポリオキシエチレン硬化ヒマシ油、ポリオキシエチレンソルビトール脂肪酸エステル等の非イオン性界面活性剤が挙げられ、これらの中でポリオキシエチレン硬化ヒマシ油が好ましい。
また、肌へのなじみの観点から、0.1〜0.3質量%含むことが好ましい。
(Surfactant)
As the surfactant, any surfactant generally used in skin cosmetics may be used, for example, polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyoxyethylene sorbitan fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid. Nonionic surfactants such as esters, polyoxyethylene glycerin fatty acid esters, polyoxyethylene hydrogenated castor oil, polyoxyethylene sorbitol fatty acid esters and the like are mentioned, and among these, polyoxyethylene hydrogenated castor oil is preferred.
Moreover, it is preferable to contain 0.1-0.3 mass% from a viewpoint of familiarity with skin.
(水溶性高分子)
水溶性高分子としては、皮膚化粧料に配合できるものであればどのようなものでもよいが、例えばトラガントガム、キサンタンガム、カルボキシビニルポリマー、アクリル酸/アクリル酸アルキル(C10−30))コポリマー、ポリアクリル酸ソーダ、ポリエチレンオキシド、エチレンオキシド・プロピレンオキシド共重合体、両性メタクリル酸エステル共重合体、ポリビニルピロリドン、ポリアクリル酸エステル共重合体エマルション、ポリ酢酸ビニルエマルション、ニトロセルロース等が挙げられ、これらの中で アクリル酸アルキル(C10−30))コポリマーが好ましい。
また、肌へのなじみの観点から、0.1〜0.5質量%含むことが好ましい。
(Water-soluble polymer)
Any water-soluble polymer may be used as long as it can be incorporated into skin cosmetics. Examples include tragacanth gum, xanthan gum, carboxyvinyl polymer, acrylic acid / alkyl acrylate (C10-30) copolymer, and polyacrylic. Acid soda, polyethylene oxide, ethylene oxide / propylene oxide copolymer, amphoteric methacrylate copolymer, polyvinyl pyrrolidone, polyacrylate copolymer emulsion, polyvinyl acetate emulsion, nitrocellulose, etc. Alkyl acrylate (C10-30)) copolymers are preferred.
Moreover, it is preferable to contain 0.1-0.5 mass% from a viewpoint of familiarity with skin.
(希釈剤)
希釈剤としては、水を用いることができる。水は、上記成分の残部を占めることができ、具体的には、50〜99.9725質量%含むことができる。
(Diluent)
Water can be used as the diluent. Water can occupy the balance of the above components, and specifically, it can be contained in an amount of 50 to 99.9925% by mass.
(その他の成分)
本発明の皮膚化粧料には、更に通常皮膚化粧料に用いられる成分、例えばセラミド類、セラミド類似構造物質、抗炎症剤、一重項酸素消去剤、抗酸化剤、アルコール類、ステロール類、血行促進剤等の薬効成分、粉体、油剤、有機酸、防腐剤、香料、紫外線吸収剤などを、本発明の効果を損なわない範囲で適宜配合できる。
(Other ingredients)
The skin cosmetic of the present invention further includes components usually used in skin cosmetics, such as ceramides, ceramide-like structural substances, anti-inflammatory agents, singlet oxygen scavengers, antioxidants, alcohols, sterols, blood circulation promoters. Medicinal components such as agents, powders, oils, organic acids, preservatives, fragrances, ultraviolet absorbers and the like can be appropriately blended within a range not impairing the effects of the present invention.
以上のような皮膚化粧料は、たとえば、水および油剤の混合液中に、美白有効成分、界面活性剤、水溶性高分子等を添加し、さらに、成分(A)および成分(A)の抽出溶媒を含むアスナロエキス、成分(B)および成分(B)の抽出溶媒を含むキキョウエキスを添加することで得られる。 The skin cosmetics as described above, for example, add a whitening active ingredient, a surfactant, a water-soluble polymer, etc. to a mixed solution of water and an oil agent, and further extract components (A) and (A). It can be obtained by adding an asunalo extract containing a solvent, an extract of the component (B) and an extract solvent containing the component (B).
なお、本発明は前述の実施形態に限定されるものではなく、本発明の目的を達成できる範囲での変形、改良等は本発明に含まれるものである。 It should be noted that the present invention is not limited to the above-described embodiments, and modifications, improvements, and the like within the scope that can achieve the object of the present invention are included in the present invention.
次に、本発明の実施例について説明する。
<赤みムラ改善剤>
(実施例1〜10、比較例1〜8)
表1に示す配合の赤みムラ改善剤を作製した。
具体的には、パラオキシ安息香酸メチルおよび精製水を80℃に加熱し、室温まで冷却した(混合液1)。
次に、上述したキキョウ根エキス、アスナロエキス、必要に応じてその他の植物エキス(クワエキス、クララエキス、アセンヤクエキス)を室温で混合し、撹拌し、均一なエキス混合液を作製した。その後、エキス混合液を混合液1に室温で添加し、撹拌して、混合液1中にエキス混合液を均一分散させた。
Next, examples of the present invention will be described.
<Redness unevenness improver>
(Examples 1-10, Comparative Examples 1-8)
A redness unevenness improving agent having the composition shown in Table 1 was prepared.
Specifically, methyl paraoxybenzoate and purified water were heated to 80 ° C. and cooled to room temperature (mixed solution 1).
Next, the above-mentioned root extract, asunaro extract, and other plant extracts (mulberry extract, clara extract, asenyaku extract) as necessary were mixed at room temperature and stirred to prepare a uniform extract mixture. Thereafter, the extract mixed solution was added to the mixed solution 1 at room temperature and stirred to uniformly disperse the extract mixed solution in the mixed solution 1.
(評価方法)
被験者(被験者:30〜60歳。シミの悩みを持つ。過去3ヶ月間に美白化粧料を使用していない。)20名に被験者自身が使用している化粧水の塗布後、各赤みムラ改善剤を適量(パール粒大)全顔に朝・晩に2週間連用塗布してもらい、10名の専門パネラーで赤みムラ改善効果の評価を行った。赤みムラ改善剤使用前に特開2002-200050号公報に開示されている装置で被験者の顔を撮影し、ヘモグロビン色素由来の色みを有する顔画像を入手し、更に2週間連用後、同様に被験者の顔を撮影し同様の顔画像を入手した。10名の専門パネラーは、使用前の画像と2週間使用後の全顔の画像を比較して赤みムラの改善度合いについて5段階評価した。改善効果が非常に高い場合を5点、非常に低い場合を1点と5段階で評価し、その平均点(少数点以下四捨五入)を求めた。
1.変化なし
2.どちらとも言えない
3.やや改善した
4.改善した
5.とても改善した
(Evaluation method)
Subjects (subjects: 30-60 years old. Have suffered from stains. No whitening cosmetics have been used in the past 3 months.) After applying the lotion used by the subjects themselves to 20 subjects, each redness unevenness was improved. Appropriate amount of agent (pearl grain size) was applied to the entire face for 2 weeks in the morning and evening, and the effect of improving redness unevenness was evaluated by 10 expert panelists. Before using the redness unevenness-improving agent, the subject's face was photographed with an apparatus disclosed in Japanese Patent Application Laid-Open No. 2002-200050, and a facial image having a color derived from a hemoglobin pigment was obtained. The face of the subject was photographed and a similar face image was obtained. Ten professional panelists compared the images before use with the images of all faces after 2 weeks of use, and evaluated the degree of improvement in redness unevenness on a five-point scale. Five points were evaluated when the improvement effect was very high, and one point was evaluated as five points when the effect was very low.
1. No change
2. I can't say either
3. Slightly improved Improved 5. So much improved
実施例1〜10の赤みムラ改善剤を使用した場合には、赤みムラ改善効果があることがわかる。実施例1〜10では、アスナロ抽出物を0.0025質量%以上、0.02質量%以下含み、キキョウ抽出物を0.025質量%以上、0.25質量%以下含んでいるため、赤みムラ改善効果が顕著なものとなっている。
特に、キキョウ抽出物の含有量が0.075質量%以上、かつ、アスナロ抽出物の含有量が0.0075質量%以上の場合には、赤みムラ改善効果が非常に大きいことがわかる。
さらに、実施例1〜10の赤みムラ改善剤を使用した場合には、素肌が明るくなったと被験者は感じていた。
一方、比較例1〜8では、キキョウ抽出物、アスナロ抽出物を併用していないため、赤みムラ改善効果がほとんどないことがわかる。
なお、ここでは、赤みムラ改善剤を作製したが、アスナロ抽出物量、キキョウ抽出物量を同じ含有量とした、皮膚化粧料を作製すれば、同様の効果があることがわかる。
It can be seen that when the redness unevenness improving agents of Examples 1 to 10 are used, there is an effect of improving redness unevenness. In Examples 1 to 10, the asunaro extract is contained in an amount of 0.0025% by mass or more and 0.02% by mass or less, and the red pepper extract is contained in an amount of 0.025% by mass or more and 0.25% by mass or less. The improvement effect is remarkable.
In particular, it can be seen that the effect of improving redness unevenness is very large when the content of the Kyodo extract is 0.075% by mass or more and the content of the Asunaro extract is 0.0075% by mass or more.
Furthermore, when using the redness unevenness improving agents of Examples 1 to 10, the subject felt that the skin became bright.
On the other hand, in Comparative Examples 1-8, it is understood that there is almost no effect of improving redness unevenness because the Kyoko extract and Asunaro extract are not used in combination.
In addition, although the redness nonuniformity improving agent was produced here, it turns out that the same effect will be produced if the skin cosmetics which made the same amount of asunaro extract amount and the amount of Kyoko extract are produced.
<皮膚化粧料>
(実施例11〜14、比較例9〜15)
表2に示す配合の皮膚化粧料を作製した。
必要に応じてカモミラET、トラネキサム酸、L−アスコルビン酸2−グルコシドのなかから選択したもの、さらには、ポリオキシエチレン硬化ヒマシ油、流動イソパラフィン、アクリル酸・メタクリル酸アルキル共重合体を80℃で加熱溶解し、この混合液に、80℃で加熱溶解したパラオキシ安息香酸メチルおよび精製水の混合液を撹拌しながら加えた(混合液3)。次に混合液3を水酸化カリウムで中和した後、さらに、撹拌しながら室温まで冷却した(混合液4)。必要に応じて、キキョウ根エキス、アスナロエキス、クワエキス、クララエキス、アセンヤクエキスを室温で撹拌してエキス混合液を得た。混合液4にエキス混合液を室温で撹拌しながら加え、ジェルを得た。
<Skin cosmetic>
(Examples 11-14, Comparative Examples 9-15)
Skin cosmetics having the formulation shown in Table 2 were prepared.
One selected from chamomile ET, tranexamic acid, L-ascorbic acid 2-glucoside as needed, and further polyoxyethylene hydrogenated castor oil, liquid isoparaffin, acrylic acid / alkyl methacrylate copolymer at 80 ° C. The mixture was heated and dissolved, and a mixed solution of methyl paraoxybenzoate and purified water dissolved by heating at 80 ° C. was added to the mixed solution with stirring (mixed solution 3). Next, the mixed solution 3 was neutralized with potassium hydroxide, and further cooled to room temperature with stirring (mixed solution 4). As necessary, the root extract, asunalo extract, mulberry extract, clara extract, and asenyaku extract were stirred at room temperature to obtain an extract mixture. The extract mixture was added to the mixture 4 with stirring at room temperature to obtain a gel.
(素肌の明るさ改善効果)
被験者20名に被験者自身が使用している化粧水の塗布後、各皮膚化粧料を適量(パール粒大)全顔に朝・晩に2週間連用塗布してもらい、素肌の明るさ改善効果の評価を行ってもらった。改善効果が高い場合を5点、低い場合を1点と5段階で自己評価を行ってもらい、その平均点(少数点以下四捨五入)を求めた。
1.改善していない
2.あまり改善していない
3.どちらともいえない
4.やや改善した
5.改善した
赤みムラ改善効果については、前記実施例1〜10と同様にして評価した。
(Skin brightness improvement effect)
After applying the lotion used by the subjects themselves to 20 subjects, the appropriate amount of each skin cosmetic (pearl size) was applied to the entire face for two weeks in the morning and evening to improve the brightness of the skin. We had you evaluate. Self-assessment was performed in 5 steps when the improvement effect was high and 1 point when the improvement effect was low, and the average (rounded to the nearest decimal point) was obtained.
1. Not improved
2. Not much improved
3. Neither Agree Nor Disagree
4). Slightly improved
5. The improved effect of improving redness unevenness was evaluated in the same manner as in Examples 1-10.
実施例11〜14では、いずれも赤みムラが改善し、被験者が素肌が明るくなったと感じていた。
これに対し、比較例9〜15では、いずれも赤みムラ改善効果がなく、また、被験者が素肌が明るくなったと感じていなかった。
In each of Examples 11 to 14, the redness unevenness was improved, and the subject felt that the skin became brighter.
On the other hand, in Comparative Examples 9 to 15, none of the redness unevenness was improved, and the subject did not feel that the skin became bright.
Claims (4)
(A)アスナロ抽出物
(B)キキョウ抽出物
を有効成分とする皮膚(頭皮を除く)の赤みムラ改善剤であって、
前記成分(A)を、当該赤みムラ改善剤全体に対して0.0075質量%以上0.015質量%以下含み、
前記成分(B)を、当該赤みムラ改善剤全体に対して0.075質量%以上0.2質量%以下含む、赤みムラ改善剤。 The following components A and B:
(A) Asunaro extract (B) Redness unevenness improving agent for skin (excluding scalp) containing Kyoko extract as an active ingredient ,
The component (A) is contained in an amount of 0.0075% by mass or more and 0.015% by mass or less based on the entire redness unevenness improving agent,
The redness nonuniformity improving agent which contains the said component (B) 0.075 mass% or more and 0.2 mass% or less with respect to the said said redness nonuniformity improving agent whole .
(A)アスナロ抽出物
(B)キキョウ抽出物
を含有する皮膚(頭皮を除く)化粧料であって、
前記成分(A)を、当該皮膚化粧料全体に対して0.0075質量%以上0.015質量%以下含み、
前記成分(B)を、当該皮膚化粧料全体に対して0.075質量%以上0.2質量%以下含む、皮膚化粧料。 The following components A and B:
(A) Asunalo extract (B) Skin (excluding scalp) cosmetics containing Kyoko extract ,
The component (A) is contained in an amount of 0.0075% by mass or more and 0.015% by mass or less based on the whole skin cosmetic,
A skin cosmetic comprising the component (B) in an amount of 0.075% by mass to 0.2% by mass with respect to the entire skin cosmetic .
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JPH0975046A (en) * | 1995-09-07 | 1997-03-25 | Masayoshi Yagisawa | Drink for taste and health food |
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